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Luan, US
Binquan Luan, Ossining, NY US
| Patent application number | Description | Published |
|---|---|---|
| 20110223652 | PIEZOELECTRIC-BASED NANOPORE DEVICE FOR THE ACTIVE CONTROL OF THE MOTION OF POLYMERS THROUGH THE SAME - Apparatus, system, and methods are provided for utilizing piezoelectric material for controlling a polymer through a nanopore. A reservoir is formed filled with conductive fluid. A membrane is formed that separates the reservoir. A nanopore is formed through the membrane. The membrane comprises electrical conductive layers, piezoelectric layers, and insulating layers. The piezoelectric layers are operative to control a size of the nanopore for clamping/releasing a polymer as well as to control the thickness of part of the membrane when a voltage is applied to the piezoelectric layers. Combinations of clamping/releasing the polymer and changing the thickness of part of the membrane can move a polymer through the nanopore at any electrically controlled speed and also stretch or break a polymer in the nanopore. | 09-15-2011 |
| 20110224098 | Nanopore Based Device for Cutting Long DNA Molecules into Fragments - Apparatus, system, and method are provided for cutting a linear charged polymer inside a nanopore. A first voltage is applied to create an electric field in a first direction. A second voltage is applied to create an electric field in a second direction, and the first direction is opposite to the second direction. When the electric field in the first direction and the electric field in the second direction are applied to a linear charged polymer inside a nanopore, the linear charged polymer is cut at a location with predetermined accuracy. | 09-15-2011 |
Hao Luan, Plano, TX US
| Patent application number | Description | Published |
|---|---|---|
| 20100031209 | Partial Timing Modeling for Gate Level Simulation - Various apparatuses, methods and systems for creating an integrated circuit and performing a gate level simulation of a circuit are disclosed herein. For example, some embodiments of the present invention provide a system for performing a gate level simulation of a circuit including a computer system, a design verification tool and an output device. The design verification tool, executable on the computer system, includes a simulator and a partial timing model generator. The partial timing model generator is operable to generate a representation of the circuit for simulation by cutting a first portion of a circuit out of a full gate level netlist for the circuit and leaving a second portion of the circuit represented by the full gate level netlist, and to overlay a simplified representation of the first portion of the circuit over the representation of the circuit. The first portion of the circuit is cut out at timing paths. The simulator is operable to perform a gate level simulation of the circuit based on the representation of the circuit. The output device is connected to the computer system and is operable to provide an indication of a result of the gate level simulation of the circuit. | 02-04-2010 |
Hongfa Luan, Austin, TX US
| Patent application number | Description | Published |
|---|---|---|
| 20110284970 | Transistor Device and Methods of Manufacture Thereof - Methods of forming transistor devices and structures thereof are disclosed. A first dielectric material is formed over a workpiece, and a second dielectric material is formed over the first dielectric material. The workpiece is annealed, causing a portion of the second dielectric material to combine with the first dielectric material and form a third dielectric material. The second dielectric material is removed, and a gate material is formed over the third dielectric material. The gate material and the third dielectric material are patterned to form at least one transistor. | 11-24-2011 |
Laura Z. Luan, Scarsdale, NY US
| Patent application number | Description | Published |
|---|---|---|
| 20080270406 | SYSTEM AND METHOD FOR ADDING COMMENTS TO KNOWLEDGE DOCUMENTS AND EXPEDITING FORMAL AUTHORING OF CONTENT - A method for modifying knowledge documents, includes: retrieving an authored document per a client request; wiki-fying a copy of the retrieved authored document; accepting client comments into the wiki-fied authored document, while maintaining the integrity of the authored documents; notifying one or more authors of the authored document of the client comments in the wiki-fied copy of the authored document; modifying the authored document based on the determination of the one or more authors to the validity of the client comments; and replacing the authored document with the modified authored document. | 10-30-2008 |
Laura Zaihua Luan, Putnam Valley, NY US
| Patent application number | Description | Published |
|---|---|---|
| 20080222645 | Process Execution Management Based on Resource Requirements and Business Impacts - Techniques are presented for managing execution of processes on a data processing system The data processing system comprises process instances that are each an execution of a corresponding process. Each process instance comprises activity instances. Business impacts are determined for the process instances, the activity instances, or both. Order of execution of the activity instances is managed by allocating resources to activity instances in order to achieve an objective defined in terms of the business impacts. In another embodiment, requests are received for the execution of the processes. For a given request, one or more of the operations of assigning, updating, aggregating, and weighting of first business impacts associated with the given request are performed to create second business impacts associated with the given request. Additionally, requests can be modified. Modification can include changing the process requested or process input as deemed appropriate, combining related requests into a single request, or both. Unmodified requests and any modified requests are managed. | 09-11-2008 |
Peng Luan, Fishers, IN US
| Patent application number | Description | Published |
|---|---|---|
| 20090136495 | ANTI-HEPCIDIN ANTIBODIES AND USES THEREOF - Monoclonal antibodies are provided that selectively bind human hepcidin-25 and are characterized as having high affinity for human hepcidin-25 and strong human mature hepcidin neutralizing properties. The antibodies of the invention are useful therapeutically for increasing serum iron levels, reticulocyte count, red blood cell count, hemoglobin, and/or hematocrit in a human and for the treatment and diagnosis of mature hepcidin-promoted disorders such as anemia, in a human subject. | 05-28-2009 |
| 20090170192 | METHODS AND DNA CONSTRUCTS FOR HIGH YIELD PRODUCTION OF POLYPEPTIDES - The invention provides an inclusion body fusion partner to increase peptide and polypeptide production in a cell. | 07-02-2009 |
| 20110189190 | ANTI-HEPCIDIN-25 SELECTIVE ANTIBODIES AND USES THEREOF - Monoclonal antibodies are provided that bind to the N-terminus of human hepcidin-25 and are characterized as having high affinity and selectivity for the polypeptide. The antibodies of the invention are useful for increasing serum iron levels, reticulocyte count, red blood cell count, hemoglobin, and/or hematocrit in a human and for the treatment of various disorders, such as anemia, in a human subject. The antibodies of the invention are also useful as analytical tools, such as in sandwich ELISA. | 08-04-2011 |
Peng Luan, Omaha, NE US
| Patent application number | Description | Published |
|---|---|---|
| 20110130556 | METHOD FOR ENZYMATIC PRODUCTION OF GLP-2(1-33) AND GLP-2(1-34) PEPTIDES - The invention provides methods for making peptides from a polypeptide containing at least one copy of the peptide using clostripain to excise the peptide from the polypeptide. The methods enable the use of a single, highly efficient enzymatic cleavage to produce any desired peptide sequence. | 06-02-2011 |
Shuan Luan, Alburquerque, NM US
| Patent application number | Description | Published |
|---|---|---|
| 20110160513 | SYSTEM AND METHODS FOR USING A DYNAMIC GAMMA KNIFE FOR RADIOSURGERY - The present invention is a method and system for developing a dynamic scheme for Gamma Knife radiosurgery based on the concept of “dose-painting” to take advantage of robotic patient positioning systems on the Gamma Knife C and Perfexion units. The spherical high dose volume created by the Gamma Knife unit will be viewed as a 3D spherical “paintbrush”, and treatment planning is reduced to finding the best route of this “paintbrush” to “paint” a 3D tumor volume. Under the dose-painting concept, Gamma Knife radiosurgery becomes dynamic, where the patient is moving continuously under the robotic positioning system. | 06-30-2011 |
Shuang Luan, Albuquerqu, NM US
| Patent application number | Description | Published |
|---|---|---|
| 20110091015 | Single-arc dose painting for precision radiation therapy - Provided herein are methods and systems for designing a radiation treatment for a subject using single arc dose painting. The methods and systems comprise an algorithm or a computer-readable product having the same, to plan the radiation treatment. The algorithm converts pairs of multiple leaf collimation (MLC) leaves to sets of leaf aperture sequences that form a shortest path single arc thereof where the pairs of MLC leaves each aligned to an intensity profile of densely-spaced radiation beams, and connects each single arc of leaf apertures to form a final treatment single arc. Also provided is a method for irradiating a tumor in a subject using single arc dose painting. | 04-21-2011 |
Wenqi Luan, Hawthorn Woods, IL US
| Patent application number | Description | Published |
|---|---|---|
| 20090257946 | METHOD AND APPARATUS FOR PRESSURIZED CALCINATION OF GYPSUM - A method for calcining gypsum in a pressurized reactor by injecting combustion gases and air into the pressurized reactor to create a fluidized bed of gypsum, and heating the fluidized bed of gypsum in the pressurized reactor sufficiently to form a calcined hemihydrate. | 10-15-2009 |
| 20110195241 | Low Weight and Density Fire-Resistant Gypsum Panel - An about ⅝ inch to ¾ inch thick low weight, low density gypsum panel with fire resistance capabilities sufficient to provide a Thermal Insulation Index of at least 17.0 minutes which when subjected to U419 test procedures will not fail for at least 30 minutes and, in selected embodiments, also has outstanding water resistance properties. | 08-11-2011 |
Yen-Tung Luan, Chelmsford, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20080274507 | METHODS OF PROTEIN PRODUCTION USING ANTI-SENESCENCE COMPOUNDS - Methods of producing a protein in cell culture comprising an anti-senescence compound, such as the antioxidant carnosine, are provided. According to teachings of the present invention, cells grown in a cell culture medium comprising an anti-senescence compound exhibit increased viability and productivity. Furthermore, cell cultures grown in the presence of an anti-senescence compound exhibit decreased levels of high molecular weight aggregates in the cell culture medium. | 11-06-2008 |
| 20090068705 | Use of Copper Glutamate in Cell Culture for Production of Polypeptides - An improved system for large scale production of polypeptides in cell culture is provided. In accordance with the present invention, cells expressing a polypeptide of interest are grown in media that contain copper, glutamate or both. The use of such a system allows production of polypeptides in which misfolding and/or aggregation are reduced, and in which total glycosylation is increased. Polypeptides expressed in accordance with the present invention may be advantageously used in the preparation of pharmaceutical, agricultural or other commercial compositions. | 03-12-2009 |
| 20090317867 | METHODS FOR ENHANCED PRODUCTION OF BONE MORPHOGENETIC PROTEINS - Methods and processes for improved recombinant protein production are provided. The methods are useful for production of growth factors, particularly those of the TGF-β superfamily, including bone morphogenetic proteins (BMPs), such as BMP-2. Suitable host cells are cultured in media where iron is present at a concentration of at least 2.25 μM and if pyridoxal is present, it makes up less than 55% of the molar concentration of vitamin B6 in the media. | 12-24-2009 |
Zhaohua Luan, Midlothian, VA US
| Patent application number | Description | Published |
|---|---|---|
| 20110017223 | AMPHIPHILE-MODIFIED SORBENTS IN SMOKING ARTICLES AND FILTERS - Smoking articles which involve the use of amphiphile-modified sorbents are disclosed. The amphiphile-modified sorbent has at least one amphiphilic compound bound to an inorganic molecular sieve substrate. The amphiphile-modified sorbent selectively removes certain constituents from cigarette smoke, while maintaining other constituents, such as those that contribute to flavor. Methods for making cigarette filters and smoking articles using amphiphile-modified sorbents, as well as methods for smoking a cigarette containing an amphiphile-modified sorbent, are also provided. | 01-27-2011 |
| 20110083684 | METHODS FOR REMOVING HEAVY METALS FROM AQUEOUS EXTRACTS OF TOBACCO - Disclosed is a method for removing one or more heavy metals from an aqueous plant extract, comprising: contacting the aqueous plant extract with, and sorbing at least a portion of the one or more heavy metals on, at least one sorbent selected from the group consisting of: one or more surface activated titanium oxide particles, one or more chitosans, one or more calcium phosphates, one or more mercaptoalkyl-substituted silica gels, one or more mercaptoalkyl-substituted mesoporous molecular sieves, one or more finely ground γ-aluminas, one or more photocatalytic titanium dioxide particles, one or more Au-anatases, ceria, and combinations thereof, to form a mixture of sorbent and heavy metal-depleted aqueous plant extract; and separating the sorbent from the mixture to provide a heavy metal-depleted aqueous plant extract. | 04-14-2011 |