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| 20100112063 | METHOD FOR PREPARING A HYDROGEL ADHESIVE HAVING EXTENDED GELATION TIME AND DECREASED DEGRADATION TIME - A method for extending the gelation time of an oxidized polysaccharide to react with a water-dispersible, multi-arm amine to form a hydrogel is disclosed. The extension of the gelation time is accomplished by using a chemical additive. The method also extends the time for the hydrogel to become tack-free, and may also be used to decrease the degradation time of the hydrogel. The chemical additive reacts with the functional groups of the oxidized polysaccharide or the water-dispersible, multi-arm amine, thereby reducing the number of groups available for crosslinking. The use of the resulting hydrogel for medical and veterinary applications is described. | 05-06-2010 |
| 20100255101 | DEXTRAN-BASED POLYMER TISSUE ADHESIVE FOR MEDICAL USE - A tissue adhesive formed by reacting an aminodextran containing primary amine groups with an oxidized dextran containing aldehyde groups is described. The dextran-based polymer tissue adhesive is particularly useful in medical applications where low swell and slow degradation are needed, for example sealing the dura, ophthalmic procedures, tissue repair, antiadhesive applications, drug delivery, and as a plug to seal a fistula or the punctum. | 10-07-2010 |
| 20100272804 | OXIDIZED CATIONIC POLYSACCHARIDE-BASED POLYMER TISSUE ADHESIVE FOR MEDICAL USE - A tissue adhesive formed by reacting an oxidized cationic polysaccharide containing aldehyde groups and amine groups with a multi-arm amine is described. The oxidized cationic polysaccharide-based polymer tissue adhesive may be useful for medical applications including wound closure, supplementing or replacing sutures or staples in internal surgical procedures such as intestinal anastomosis and vascular anastomosis, ophthalmic procedures, drug delivery, anti-adhesive applications and as a bulking agent to treat urinary incontinence. Additionally, due to the presence of the positively charged amine groups on the oxidized polysaccharide, the polymer tissue adhesive disclosed herein may promote wound healing and blood coagulation, and may possess antimicrobial properties. | 10-28-2010 |
| 20110017985 | ELECTRONIC DEVICE UTILIZING FLUORINATED CARBON NANOTUBES - The present invention is an electronic device and a process for making the electronic device in which the semiconductor component comprises at least one carbon nanotube functionalized with a fluorinated olefin. Functionalization with the fluorinated olefin renders the carbon nanotube semiconducting. | 01-27-2011 |
| 20110224724 | HYDROGEL TISSUE ADHESIVE FORMED FROM AMINATED POLYSACCHARIDE AND ALDEHYDE-FUNCTIONALIZED MULTI-ARM POLYETHER - A hydrogel tissue adhesive formed by reacting an aminated polysaccharide with a water-dispersible, aldehyde-functionalized multi-arm polyether is described. The hydrogel tissue adhesive may be useful as a general tissue adhesive and sealant for medical and veterinary applications such as wound closure, supplementing or replacing sutures or staples in internal surgical procedures such as intestinal anastomosis and vascular anastomosis, tissue repair, ophthalmic procedures, drug delivery, and to prevent post-surgical adhesions. Additionally, due to the presence of the aminated polysaccharide, the hydrogel tissue adhesive may also promote wound healing and blood coagulation, and provide antimicrobial properties. | 09-15-2011 |
| 20120004194 | ALDEHYDE-FUNCTIONALIZED POLYSACCHARIDES - Novel aldehyde-functionalized polysaccharide compositions are described that are more stable in aqueous solution than oxidized polysaccharides or other types of polysaccharides containing pendant aldehyde groups. The aldehyde-functionalized polysaccharides may be reacted with various amine-containing polymers to form hydrogel tissue adhesives and sealants that may be useful for medical applications such as wound closure, supplementing or replacing sutures or staples in internal surgical procedures such as intestinal anastomosis and vascular anastomosis, tissue repair, preventing leakage of fluids such as blood, bile, gastrointestinal fluid and cerebrospinal fluid, ophthalmic procedures, drug delivery, and preventing post-surgical adhesions. | 01-05-2012 |
| 20120148523 | HYDROGEL TISSUE ADHESIVE FOR MEDICAL USE - A hydrogel tissue adhesive formed by reacting an aldehyde-functionalized polysaccharide containing pendant aldehyde groups with a water-dispersible, multi-arm amine is described. The hydrogel may be useful as a tissue adhesive or sealant for medical applications that require a more rapid degradation time, such as the prevention of undesired tissue-to tissue adhesions resulting from trauma or surgery. | 06-14-2012 |
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| 20090087466 | PROCESS FOR PROVIDING ANTIMICROBIAL SURFACES - Processes for providing durable antimicrobial surfaces are disclosed that comprise treating a polymer substrate surface with formaldehyde followed by treatment with an antimicrobial peptide. Further embodiments include articles, including medical devices, characterized by a durable antimicrobial surface provided by the processes of the invention. | 04-02-2009 |
| 20100015231 | LOW SWELL, LONG-LIVED HYDROGEL SEALANT - A low swell, long-lived hydrogel sealant formed by reacting a highly oxidized polysaccharide containing aldehyde groups with a multi-arm amine is described. The hydrogel sealant may be particularly suitable for applications requiring low swell and slow degradation, for example, ophthalmic applications such as sealing wounds resulting from trauma such as corneal lacerations, or from surgical procedures such as vitrectomy procedures, cataract surgery, LASIK surgery, glaucoma surgery, and corneal transplants; neurosurgery applications, such as sealing the dura; and as a plug to seal a fistula or the punctum. The low swell, long-lived hydrogel sealant may also be useful as a tissue sealant and adhesive, and as an anti-adhesion barrier. | 01-21-2010 |
| 20100016886 | HIGH SWELL, LONG-LIVED HYDROGEL SEALANT - A high swell, long-lived hydrogel sealant formed by reacting a highly oxidized polysaccharide containing aldehyde groups with a multi-arm amine is described. The hydrogel sealant may be particularly suitable for applications requiring high swell and slow degradation, for example, tissue augmentation, both cosmetic and reconstructive; void filling; tissue bulking, for example treatment of urinary incontinence and acid reflux; and embolization. The high swell, long-lived hydrogel sealant may also be useful as a tissue sealant and adhesive, and as an anti-adhesion barrier. | 01-21-2010 |
| 20100140590 | TRANSISTOR COMPRISING CARBON NANOTUBES FUNCTIONALIZED WITH A NON-FLUORO CONTAINING ELECTRON DEFICIENT OLEFIN OR ALKYNE - The present invention is a transistor and a process for making the transistor in which the semiconductor component comprises at least one carbon nanotube functionalized by cycloaddition with a fluorinated olefin. Functionalization with the fluorinated olefin renders the carbon nanotube semiconducting. | 06-10-2010 |
| 20120142787 | ALDEHYDE-FUNCTIONALIZED POLYSACCHARIDES - Novel aldehyde-functionalized polysaccharide compositions containing pendant dialdehyde groups are described that are more stable in aqueous solution than oxidized polysaccharides. The aldehyde-functionalized polysaccharides may be reacted with various amine-containing polymers to form hydrogel tissue adhesives and sealants that may be useful for medical applications such as wound closure, supplementing or replacing sutures or staples in internal surgical procedures such as intestinal anastomosis and vascular anastomosis, tissue repair, preventing leakage of fluids such as blood, bile, gastrointestinal fluid and cerebrospinal fluid, ophthalmic procedures, drug delivery, and preventing post-surgical adhesions. | 06-07-2012 |
| 20120285930 | PRINTING FORM AND PROCESS FOR PREPARING THE PRINTING FORM WITH CURABLE COMPOSITION HAVING EPOXY NOVOLAC RESIN - The invention pertains to a printing form and a process for preparing the printing form from a curable composition that includes an epoxy novolac resin having an epoxide equivalent weight of 156 to 300 g/equivalent, and an amine curing agent selected from primary amines and secondary amines, the agent having an amine equivalent weight of less than or equal to 60 g/equivalent. The process includes applying the curable composition to a supporting substrate to form a layer, curing the layer at one or more temperatures in a temperature range, and engraving to form at least one cell in the cured layer. The process prepares printing forms, particularly gravure printing forms, having a cured resin composition layer that is engravable, resistant to solvent inks and to mechanical wear, and capable of printing gravure-quality images. | 11-15-2012 |
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| 20110058720 | Systems and Methods for Automatic Vertebra Edge Detection, Segmentation and Identification in 3D Imaging - Systems and methods for automatic accurate and efficient segmentation and identification of one or more vertebra in digital medical images using a coarse-to-fine segmentation. | 03-10-2011 |
| 20110064289 | Systems and Methods for Multilevel Nodule Attachment Classification in 3D CT Lung Images - Automated and semi-automated systems and methods for detection and classification of structures within 3D lung CT images using voxel-level segmentation and subvolume-level classification. | 03-17-2011 |
| 20110075920 | Multi-Level Contextual Learning of Data - Described herein is a framework for automatically classifying a structure in digital image data are described herein. In one implementation, a first set of features is extracted from digital image data, and used to learn a discriminative model. The discriminative model may be associated with at least one conditional probability of a class label given an image data observation Based on the conditional probability, at least one likelihood measure of the structure co-occurring with another structure in the same sub-volume of the digital image data is determined. A second set of features may then be extracted from the likelihood measure. | 03-31-2011 |
| 20120088981 | Matching of Regions of Interest Across Multiple Views - Described herein is a framework for multi-view matching of regions of interest in images. According to one aspect, a processor receives first and second digitized images, as well as at least one CAD finding corresponding to a detected region of interest in the first image. The processor determines at least one candidate location in the second image that matches the CAD finding in the first image. The matching is performed based on local appearance features extracted for the CAD finding and the candidate location. In accordance with another aspect, the processor receives digitized training images representative of at least first and second views of one or more regions of interest. Feature selection is performed based on the training images to select a subset of relevant local appearance features to represent instances in the first and second views. A distance metric is then learned based on the subset of local appearance features. The distance metric may be used to perform matching of the regions of interest. | 04-12-2012 |
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| 20090208648 | ARTICLE HAVING NANO-SCALED STRUCTURES AND A PROCESS FOR MAKING SUCH ARTICLE - A process for producing an article having modified optical, chemical, and/or physical properties is disclosed. The process includes (a) fluidizing a starting material; (b) forcing the fluidized starting material toward the article; and (c) passing the fluidized starting material through a high energy zone. The passing step can occur before the forcing step; after the forcing step but before the fluidizing material comes in contact with the surface of the article; and/or after the forcing step and after the fluidized material comes in contact with the surface of the article. The properties of the article are modified because the article has nano-scaled structures distributed on the surface of the article and/or at least partially embedded in the article. | 08-20-2009 |
| 20100124642 | UNDERCOATING LAYERS PROVIDING IMPROVED CONDUCTIVE TOPCOAT FUNCTIONALITY - A coated article includes a substrate and a first coating formed over at least a portion of the substrate. The first coating includes a mixture of oxides including oxides of at least two of P, Si, Ti, Al and Zr. A conductive functional coating is formed over at least a portion of the first coating. In one embodiment, the functional coating includes fluorine doped tin oxide. | 05-20-2010 |
| 20100124643 | UNDERCOATING LAYERS PROVIDING IMPROVED PHOTOACTIVE TOPCOAT FUNCTIONALITY - A coated article includes a substrate and a first coating formed over at least a portion of the substrate. The first coating includes a mixture of oxides including oxides of at least two of P, Si, Ti, Al and Zr. A photoactive functional coating is formed over at least a portion of the first coating. In one embodiment, the functional coating includes titania. | 05-20-2010 |
| 20100285290 | UNDERCOATING LAYERS PROVIDING IMPROVED TOPCOAT FUNCTIONALITY - A coated article includes a substrate and a first coating formed over at least a portion of the substrate. The first coating includes a mixture of oxides including oxides of at least two of P, Si, Ti, Al and Zr. A functional coating is formed over at least a portion of the first coating. In one embodiment, the functional coating includes fluorine doped tin oxide. In another embodiment, the functional coating includes titania. | 11-11-2010 |
| 20110146767 | SILICON THIN FILM SOLAR CELL HAVING IMPROVED HAZE AND METHODS OF MAKING THE SAME - A method of increasing the haze of a coating stack having a top layer and an undercoating layer using a chemical vapor deposition coating process includes at least one of: increasing a precursor flow rate; decreasing a carrier gas flow rate; increasing a substrate temperature; increasing a water flow rate; decreasing an exhaust flow rate; and increasing a thickness of at least one of the top layer or undercoating layer. | 06-23-2011 |
| 20110146768 | SILICON THIN FILM SOLAR CELL HAVING IMPROVED UNDERLAYER COATING - A silicon thin film solar cell includes a substrate and an undercoating formed over at least a portion of the substrate. The undercoating includes first layer having tin oxide or titania and a second layer having a mixture of oxides of at least two of Sn, P, Si, Ti, Al and Zr. A conductive coating is formed over at least a portion of the first coating, wherein the conductive coating includes oxides of one or more of Zn, Fe, Mn, Al, Ce, Sn, Sb, Hf, Zr, Ni, Zn, Bi, Ti, Co, Cr, Si or In or an alloy of two or more of these materials. | 06-23-2011 |
| 20110154860 | Methods Of Making Colored Glass By Surface Modification - A method of making colored glass in a float glass process includes the steps of: melting glass batch materials in a furnace to form a glass melt; transporting the glass melt into a float glass chamber having a flame spray device, the glass melt forming a float glass ribbon; supplying at least one coating material to the flame spray device to form a spray having coating particles; and directing the spray onto the float glass ribbon to diffuse the particles into the surface of the float glass ribbon to form a glass sheet of a desired color. | 06-30-2011 |
| 20110155685 | REFLECTIVE COATINGS FOR GLASS ARTICLES, METHODS OF DEPOSITION, AND ARTICLES MADE THEREBY - The present invention is directed toward a coating apparatus of the invention comprising at least one coating chamber having at least one makeup air conduit in flow communication with the coating chambers via a makeup air pathway connecting the makeup air conduit to the coating chamber. At least one coating member is positioned in the coating chamber. The coating member is in flow communication with a source of coating material including a titanium-containing coating material. At least one exhaust member is in flow communication with the coating chamber via an exhaust pathway for removing excess coating and air from the coating chamber. | 06-30-2011 |
| 20110262757 | METHOD OF DEPOSITING NIOBIUM DOPED TITANIA FILM ON A SUBSTRATE AND THE COATED SUBSTRATE MADE THEREBY - A coated article includes a pyrolytic applied transparent electrically conductive oxide film of niobium doped titanium oxide. The article can be made by using a coating mixture having a niobium precursor and a titanium precursor. The coating mixture is directed toward a heated substrate to decompose the coating mixture and to deposit a transparent electrically conductive niobium doped titanium oxide film on the surface of the heated substrate. In one embodiment of the invention, the method is practiced using a vaporized coating mixture including a vaporized niobium precursor; a vaporized titanium precursor, and a carrier gas to deposit a niobium doped titanium oxide film having a sheet resistance greater than 1.2 and an index of refraction of 2.3 or greater. The chemical formula for the niobium doped titanium oxide is Nb:TiO | 10-27-2011 |
| 20120114846 | COATED SUBSTRATES HAVING UNDERCOATING LAYERS THAT EXHIBIT IMPROVED PHOTOCATALYTIC ACTIVITY - A coated substrate is disclosed. The coated substrate includes a substrate; an undercoating layer comprising at least one layer selected from a mixture of silica and zirconia; a mixture of silica and alumina; or a mixture of silica, alumina and titania overlaying at least a portion of the substrate; and a functional coating overlaying at least a portion of the undercoating. The coated substrates of the invention exhibit improved properties such as increased durability, photocatalytic activity, etc. as a result of the undercoating layer. | 05-10-2012 |
| 20120172209 | UNDERCOATING LAYERS PROVIDING IMPROVED PHOTOACTIVE TOPCOAT FUNCTIONALITY - A coated article includes a substrate and a first coating formed over at least a portion of the substrate. The first coating includes a mixture of oxides including oxides of at least two of P, Si, Ti, Al and Zr. A photoactive functional coating is formed over at least a portion of the first coating. In one embodiment, the functional coating includes titanic. | 07-05-2012 |
| 20120200929 | LIGHT EXTRACTING SUBSTRATE FOR ORGANIC LIGHT EMITTING DIODE - A light extraction substrate includes a glass substrate having a first surface and a second surface. A first light extraction region can be defined on and/or adjacent the first surface. The first light extraction region includes nanoparticles. A second light extraction region can be defined on at least a part of the second surface. The second light extraction region has a surface roughness of at least 10 nm. | 08-09-2012 |
| 20120231279 | PROCESS FOR MAKING POLYMERS HAVING NANOSTRUCTURES INCORPORATED INTO THE MATRIX OF THE POLYMER - The present invention is directed toward a method for making a polymer that has nanostructures incorporated into the matrix of the polymer. The method of the present invention involves mixing a precursor solution for the polymer with a precursor for the nanostructures to form a mixture. Nanostructures are formed in the mixture from the precursor of the nanostructures, such that the nanostructures are surrounded by the precursor solution for the polymer. The polymer is formed from the precursor solution of the polymer, which results in the nanostructures being incorporated into the matrix of the polymer. | 09-13-2012 |
| 20120237777 | PROCESS FOR FORMING AN ANTI-FOULING COATING SYSTEM - Provided is a process for forming a durable anti-fouling coating on a substrate including:
| 09-20-2012 |
| 20120275018 | COATED GLASSES HAVING A LOW SOLAR FACTOR - A glass transparency for an automotive roof window includes a solar control coating on a surface of a glass substrate to provide the coated glass with a solar factor in the range of equal to or less 30%, and an Lta in the range of greater than 0% to less than 50%. The solar factor is determined in accordance with ISO 13837 (2008). In another embodiment of the invention, the transparency is a laminated transparency having the solar control coating between two glass sheets. | 11-01-2012 |
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| 20090017457 | IDENTIFICATION OF MODULATORS OF SERINE PROTEASE INHIBITOR KAZAL AND THEIR USE AS ANTI-CANCER AND ANTI-VIRAL AGENTS - This invention describes a relevant etiology of cancer and a novel anti-cancer therapeutic strategy, based on the discovery that a protein named serine protease inhibitor (SPIK/SPINK/PSTI) was up-regulated by hepatitis B and C virus infections consequently suppressing the cell apoptosis. Accordingly, this invention provides an inhibitor of SPIK and/or a technology of suppression of over-expression of SPIK in cells. The inhibitors include: 1) chemical compounds, which can inhibit SPIK transcripts, protein activity, and gene expression, 2) SPIK siRNA (RNAi gene silence or dsRNA of SPIK, 3) DNA anti-sense and anti-SPIK antibody. Further, this invention provides a method of using the inhibitor as an anti-cancer agent to re-instate cancer cell apoptosis (e.g., serine protease dependent cell apoptosis). | 01-15-2009 |
| 20120244160 | IDENTIFICATION OF MODULATORS OF SERINE PROTEASE INHIBITOR KAZAL AND THEIR USE AS ANTI-CANCER AND ANTI-VIRAL AGENTS - This disclosure describes a relevant etiology of cancer and a novel anti-cancer therapeutic strategy, based on the discovery that a protein named serine protease inhibitor (SPIK/SPINK/PSTI) was up-regulated by hepatitis B and C virus infections consequently suppressing the cell apoptosis. Accordingly, the present disclosure provides, inter alia, an inhibitor of SPIK and/or a technology of suppression of over-expression of SPIK in cells. The inhibitors include: 1) chemical compounds, which can inhibit SPIK transcripts, protein activity, and gene expression, 2) SPIK siRNA (RNAi gene silence or dsRNA of SPIK, 3) DNA anti-sense and anti-SPIK antibody. Further, this disclosure provides methods of using the inhibitor as an anti-cancer agent to re-instate cancer cell apoptosis (e.g., serine protease dependent cell apoptosis). | 09-27-2012 |
