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László Balázs, God HU
| Patent application number | Description | Published |
|---|---|---|
| 20100210838 | FLUOROPYRROLIDINES HAVING DIPEPTIDYL PEPTIDASE ENZYME INHIBITORY ACTIVITY - The present invention relates to new, potent DPP-IV enzyme inhibitors of the general formula (I), which contain fluorine atoms. | 08-19-2010 |
László BalÁzs, Dunakeszi HU
| Patent application number | Description | Published |
|---|---|---|
| 20110118305 | COMPOUNDS - Heterocyclic amides useful as inhibitors of dipeptylpeptidase-IV (DPP-IV) enzyme, process for the preparation thereof and intermediates therefore. | 05-19-2011 |
László Bánkuti, Budapest HU
| Patent application number | Description | Published |
|---|---|---|
| 20110012509 | COMPACT FLUORESCENT LAMP AND METHOD FOR MANUFACTURING - This compact fluorescent lamp comprises a discharge tube arrangement with at least one discharge tube. The tube is formed of glass, encloses a discharge volume filled with a discharge gas and has a fluorescent phosphor coating disposed on the inner surface of the tube. The tube forms a continuous arc path and the tube is provided with electrodes disposed at each end of the arc path. The lamp also comprises a ballast circuit connected to the electrodes for controlling the current in the tube and a lamp base for connecting said lamp to a power supply through a socket. The lamp is enclosed in an outer envelope comprising a substantially spherical portion enclosing the tube arrangement and an elongated end portion enclosing the ballast circuit. The end portion of the outer envelope is closed and sealed by a sealing means of the same material as the material of the outer envelope. The sealing means is connected to the envelope in a hermetically sealing way. | 01-20-2011 |
László Bánkuti, Budapest HU
| Patent application number | Description | Published |
|---|---|---|
| 20080278057 | BULB-SHAPED OUTER ENVELOPE FOR LAMPS, METHOD FOR MANUFACTURE THEREOF, AND COMPACT FLUORESCENT LAMP THEREWITH - A bulb-shaped outer envelope for accommodating at least one lamp including a light-emitting body and a control gear is disclosed. The envelope has a substantially spherical section for receiving the light-emitting body, and an elongated end section for receiving at least a part of the control gear components. The elongated end section is provided with a neck section. A substantially tubular neck-extension portion connects to an inner surface portion of and protruding from the neck section. The neck-extension portion is suitable for accommodating a remaining part of the control gear components. In a method for the manufacture of a glass outer envelope, a flare that is normally used in the manufacture of incandescent lamps is turned around by 180°, put into a skirted bulbous envelope, melted into the envelope while the skirt is detached and the flare is formed into a neck-extension portion. A self-ballasted compact fluorescent lamp with the bulb-shaped outer envelope is also disclosed. A part of the ballast components are disposed in the neck-extension portion of the outer envelope. | 11-13-2008 |
| 20090066250 | DIELECTRIC BARRIER DISCHARGE LAMP - A dielectric barrier discharge lamp comprises multiple tubular discharge vessels of a substantially equivalent size and having a principal axis. Each discharge vessel encloses a discharge volume filled with a discharge gas. The discharge vessels are arranged substantially parallel to their principal axis and adjacent to each other. The lamp also comprises a first set of interconnected electrodes and a second set of interconnected electrodes. The electrodes are isolated from the discharge volume by at least one dielectric layer. At least one of the dielectric layers is constituted by the wall of the discharge vessel, and the electrodes of at least one electrode set are located between the discharge vessels. In one embodiment, the discharge vessels are adjacent to each other in a lattice, and the first and second electrode sets are located between the discharge vessels in interstitial voids of the lattice. In another embodiment, the discharge vessels are arranged adjacent to each other along generatrices of a prism. | 03-12-2009 |
| 20090167184 | COMPACT FLUORESCENT LAMP WITH MECHANICAL SUPPORT MEANS AND STARTING AID - The compact fluorescent lamp comprises a bulb shaped outer envelope enclosing a discharge tube having a coiled configuration and a ballast unit for controlling the current in the tube. The lamp further comprises at least one joint mechanical support and starting aid means for positioning the discharge tube and the ballast unit and reducing a breakdown voltage path of the discharge tube. The at least one mechanical support and starting aid means is made of an electrically conducting material and connected electrically to at least one of the electrodes. The neck portion has a retaining member, and the mechanical support and starting aid means is supported by the retaining member and clamped on the discharge tube at least at a location in a vicinity of a middle section of the arc path. The mechanical support means further comprises at least one support section to provide support against an apex of the outer envelope, and at least one fixing section for fixing of the discharge tube. | 07-02-2009 |
| 20100026182 | ELECTRIC LAMP WITH INNER ASSEMBLY AND OUTER BULB AND METHOD FOR MANUFACTURING - An electric lamp comprises an inner assembly including a light source and a control gear circuit. An outer envelope encloses the light source and at least a part of the control gear and has a predetermined wall thickness and an end portion. The outer envelope is comprised of two parts separated along a circumferential line. The two parts of the envelope are connectable and sealable to form a uniform outer envelope with a seal region. The seal region has a wall thickness and is merged in a surface portion of the two parts of the envelope so that the surface unevenness of the seal region is not greater than 0.5 millimeters, and the maximum difference of the wall thickness of the seal region with respect to the wall thickness of the outer envelope is not greater than 0.3 millimeters. | 02-04-2010 |
| 20110012509 | COMPACT FLUORESCENT LAMP AND METHOD FOR MANUFACTURING - This compact fluorescent lamp comprises a discharge tube arrangement with at least one discharge tube. The tube is formed of glass, encloses a discharge volume filled with a discharge gas and has a fluorescent phosphor coating disposed on the inner surface of the tube. The tube forms a continuous arc path and the tube is provided with electrodes disposed at each end of the arc path. The lamp also comprises a ballast circuit connected to the electrodes for controlling the current in the tube and a lamp base for connecting said lamp to a power supply through a socket. The lamp is enclosed in an outer envelope comprising a substantially spherical portion enclosing the tube arrangement and an elongated end portion enclosing the ballast circuit. The end portion of the outer envelope is closed and sealed by a sealing means of the same material as the material of the outer envelope. The sealing means is connected to the envelope in a hermetically sealing way. | 01-20-2011 |
| 20110181176 | POSITIONING OF AUXILIARY AMALGAM - A fluorescent lamp includes a discharge tube and an auxiliary amalgam assembly held in the discharge tube by a holder. The holder has first and second regions with attaching portions adapted to receive an associated attachment member. The holder has a first dimension prior to disposition in the discharge tube. | 07-28-2011 |
| 20110304258 | POSITIONING OF AUXILIARY AMALGAM - A compact fluorescent lamp includes a discharge tube such as a spiral discharge tube having a wall forming a discharge chamber between cathodes at first and second ends thereof. At least one auxiliary amalgam assembly is disposed in the discharge chamber at an intermediate region disposed between the first and second ends. The auxiliary amalgam assembly is secured at a location spaced from the inner wall of the discharge chamber. | 12-15-2011 |
| 20120019136 | COMPACT FLUORESCENT LAMP WITH IMPROVED THERMAL MANAGEMENT - A compact fluorescent lamp includes an inverted compact fluorescent light source housed within an outer envelope. Locating the first and second ends of the coiled CFL source positions the electrodes within a substantially spherical outer envelope at a location remotely spaced from the ballast compartment. In this manner, only small diameter first and second lead wires that mechanically and electrically engage the electrodes pass through small dimensioned passages in a separation member in the outer envelope cavity. This substantially reduces the thermal stress on the components. | 01-26-2012 |
László Csizmadia, Gyor HU
| Patent application number | Description | Published |
|---|---|---|
| 20100086245 | Method for producing and/or assembling a bearing as well as bearing - The invention relates to a method for producing and/or assembling a bearing with a bearing bore, a journal which is located in the bearing bore and at least two bearing shells which at least partially encompass the journal in the bearing bore, there being a number n of tolerance classes. Here the bearing class width C | 04-08-2010 |
László Csizmadia, Gyor HU
| Patent application number | Description | Published |
|---|---|---|
| 20100086245 | Method for producing and/or assembling a bearing as well as bearing - The invention relates to a method for producing and/or assembling a bearing with a bearing bore, a journal which is located in the bearing bore and at least two bearing shells which at least partially encompass the journal in the bearing bore, there being a number n of tolerance classes. Here the bearing class width C | 04-08-2010 |
László Czibula, Budapest HU
| Patent application number | Description | Published |
|---|---|---|
| 20120059034 | NOVEL CRYSTALLINE HYDRATE, AMORPHOUS AND POLYMORPHIC FORMS OF DIHYDRO-BENZOXAZOLE-6-YL-ACETAMIDE DERIVATIVE AND PROCESSES FOR THEIR PREPARATION - The invention relates to novel crystalline hydrate, amorphous and crystalline polymorphic forms of 2-[4-(4-Fluoro-benzyl)-piperidine-1-yl]-2-oxo-N-(2-oxo-2,3-dihydro-benzoxazole-6-yl)-acetamide (I) (radiprodil). Processes for the preparation of these forms, compositions containing these forms, and methods of use thereof are also described. | 03-08-2012 |
László Czirják, Pécs HU
| Patent application number | Description | Published |
|---|---|---|
| 20110136140 | DIAGNOSIS OF SYSTEMIC DISEASES - It has been found that the pattern of recognized topo I epitopes is different between dcSSc, IcSSc and SLE patients. Fragment F4 (amino acid (AA) 450-600) was recognized by all patients tested. Fragment F1 (AA 5-30) and Fragment F8 (AA 350-400) represent characteristic epitopes for dcSSc and SLE, respectively. The invention relates to diagnostic uses and methods as well as kits for use in diagnosis. | 06-09-2011 |
László Domjan, Budapest HU
| Patent application number | Description | Published |
|---|---|---|
| 20090015920 | MULTIPLE IMAGING ARRANGEMENTS FOR HEAD MOUNTED DISPLAYS - A head mounted display is disclosed that utilizes a single video display screen to transport images to both eyes. Multiple reflections are created by illuminating the display screen form a plurality of directions, or by illuminating the display screen with light beams of differing polarizations. The reflections of the display screen are focused in order to reduce the splitting volume and then redirected by a plurality of reflective surfaces located near the focal point of the display images. Different images may be sent to each eye of a user by interlacing multiple data streams for the display and linking each data stream with a specific illumination direction, or specific polarization. | 01-15-2009 |
| 20090097086 | Lens system for common aperture holographic storage system - The present invention relates to a lens system for an apparatus for reading from and/or writing to holographic storage media, and more specifically to a lens system optimized for an apparatus with a coaxial common aperture arrangement of an object beam and a reference beam. | 04-16-2009 |
| 20100290126 | Multiple Imaging Arrangements for Head Mounted Displays - A head mounted display is disclosed that utilizes a single video display screen to transport images to both eyes. Multiple reflections are created by illuminating the display screen form a plurality of directions, or by illuminating the display screen with light beams of differing polarizations. The reflections of the display screen are focused in order to reduce the splitting volume and then redirected by a plurality of reflective surfaces located near the focal point of the display images. Different images may be sent to each eye of a user by interlacing multiple data streams for the display and linking each data stream with a specific illumination direction, or specific polarization. | 11-18-2010 |
László Domjan, Budapest HU
| Patent application number | Description | Published |
|---|---|---|
| 20100290126 | Multiple Imaging Arrangements for Head Mounted Displays - A head mounted display is disclosed that utilizes a single video display screen to transport images to both eyes. Multiple reflections are created by illuminating the display screen form a plurality of directions, or by illuminating the display screen with light beams of differing polarizations. The reflections of the display screen are focused in order to reduce the splitting volume and then redirected by a plurality of reflective surfaces located near the focal point of the display images. Different images may be sent to each eye of a user by interlacing multiple data streams for the display and linking each data stream with a specific illumination direction, or specific polarization. | 11-18-2010 |
László Dudás, Beremend HU
| Patent application number | Description | Published |
|---|---|---|
| 20110261447 | Optical Microscope System And Method Carried Out Therewith For Reconstructing An Image Of An Object - The invention is an optical microscope system ( | 10-27-2011 |
László Ébert, Budaors HU
| Patent application number | Description | Published |
|---|---|---|
| 20120067739 | COLLOID DECOMPOSITION METHOD AND APPARATUS FOR ELECTROCHEMICALLY RESOLVING EMULSIONS - Decomposition is performed with the application of the method and apparatus by separating solid contaminants from the emulsion, absorbing CO | 03-22-2012 |
László Fésüs, Debrecen HU
| Patent application number | Description | Published |
|---|---|---|
| 20100008886 | APPLICATION OF THE OIL FRACTION OBTAINED FROM SOUR CHERRY (PRUNUS CESARUS) SEED KERNEL - The present invention relates to the use of the oil components of sour cherry ( | 01-14-2010 |
| 20110129553 | PROCESS FOR THE PREPARATION OF SOUR CHERRY SEED EXTRACT, USE OF THE EXTRACT FOR THE PREPARATION OF PHARMACEUTICAL COMPOSITIONS AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAID EXTRACT - The present invention relates to a process for the isolation of the components of seed of | 06-02-2011 |
László Fésüs, Debrecen HU
| Patent application number | Description | Published |
|---|---|---|
| 20100008886 | APPLICATION OF THE OIL FRACTION OBTAINED FROM SOUR CHERRY (PRUNUS CESARUS) SEED KERNEL - The present invention relates to the use of the oil components of sour cherry ( | 01-14-2010 |
László Hévizi, Piliscsaba HU
| Patent application number | Description | Published |
|---|---|---|
| 20120009926 | SECONDARY RADIO-NODES FOR MOBILE COMMUNICATIONS NETWORKS AND RELATED METHODS - A mobile communications network may include a primary and secondary radio-nodes, and the secondary radio-node may include a radio-node transmitter and a radio-node receiver. A method of operating the secondary radio-node may include monitoring through the radio-node receiver of the secondary radio-node to detect user terminal signals transmitted to the primary radio-node while maintaining the secondary radio-node in a sleep mode. Responsive to detecting user terminal signals during monitoring in the sleep-mode, operation of the secondary radio-node may be changed from the sleep mode to an active mode. | 01-12-2012 |
László Hiripi, Godollo HU
| Patent application number | Description | Published |
|---|---|---|
| 20100041743 | TRANSGENIC ANIMAL WITH ENHANCED IMMUNE RESPONSE AND METHOD FOR THE PREPARATION THEREOF - The present invention provides a method for producing a transgenic (Tg) non-human animal capable of developing an enhanced humoral immune response against an antigen as compared to a non-transgenic control animal of the same species, comprising introducing into said non-human animal a genetic construct providing for enhanced MHC class I-related neonatal Fc receptor (FcRn) activity. Also provided a Tg non-human animal comprising a genetic construct providing for enhanced FcRn activity, as well as the use of such animal in a non-therapeutical method. Therapeutic genetic constructs and methods are also provided. The present invention further provides methods for producing immunoglobulins. | 02-18-2010 |
László Janovák, Kunbaja HU
| Patent application number | Description | Published |
|---|---|---|
| 20100239672 | LAYER SILICATE NANOCOMPOSITES OF POLYMER HYDROGELS AND THEIR USE IN TISSUE EXPANDERS - The invention relates to nanocomposites comprising of (i) hydrogels synthetized by copolymerization of N-isopropylacrylamide and/or acrylamide and/or acrylic acid monomers and of (ii) layer silicates, and to the process for preparing them. The invention covers osmotically active hydrogel expanders containing said nano-composites, suitable for tissue expansion and the use of said materials for obtaining live skin. | 09-23-2010 |
László Janovák, Kunbaja HU
| Patent application number | Description | Published |
|---|---|---|
| 20100239672 | LAYER SILICATE NANOCOMPOSITES OF POLYMER HYDROGELS AND THEIR USE IN TISSUE EXPANDERS - The invention relates to nanocomposites comprising of (i) hydrogels synthetized by copolymerization of N-isopropylacrylamide and/or acrylamide and/or acrylic acid monomers and of (ii) layer silicates, and to the process for preparing them. The invention covers osmotically active hydrogel expanders containing said nano-composites, suitable for tissue expansion and the use of said materials for obtaining live skin. | 09-23-2010 |
László Jaszlits, Budapest HU
| Patent application number | Description | Published |
|---|---|---|
| 20100267711 | METHOD OF ENHANCING CELLULAR PRODUCTION OF MOLECULAR CHAPERONE, HYDROXYLAMINE DERIVATIVES USEFUL FOR ENHANCING THE CHAPERONE PRODUCTION AND THE PREPARATION THEREOF - A method of increasing expression of a molecular chaperon by a cell and/or enhancing the activity of a molecular chaperon in cells is provided. The method comprises treating a cell that is exposed to a physiological stress which induces expression of a molecular chaperon by the cell with an effective amount of a certain hydroxylamine derivative to increase the stress. Alternatively, an hydroxylamine derivative can be administrated to a cell before it is exposed to a physiological stress which induces expression of a molecular chaperon by the cell. Preferably, the cell to which an hydroxylamine derivative is administered is an eukaryotic cell. The hydroxylamine derivative corresponds to the formulae (I) or (II). | 10-21-2010 |
László Jaszlits, Budapest HU
| Patent application number | Description | Published |
|---|---|---|
| 20090214677 | Pharmaceutical Composition Containing an Extract of a Solidago Species - An extract of a part of a | 08-27-2009 |
| 20100267711 | METHOD OF ENHANCING CELLULAR PRODUCTION OF MOLECULAR CHAPERONE, HYDROXYLAMINE DERIVATIVES USEFUL FOR ENHANCING THE CHAPERONE PRODUCTION AND THE PREPARATION THEREOF - A method of increasing expression of a molecular chaperon by a cell and/or enhancing the activity of a molecular chaperon in cells is provided. The method comprises treating a cell that is exposed to a physiological stress which induces expression of a molecular chaperon by the cell with an effective amount of a certain hydroxylamine derivative to increase the stress. Alternatively, an hydroxylamine derivative can be administrated to a cell before it is exposed to a physiological stress which induces expression of a molecular chaperon by the cell. Preferably, the cell to which an hydroxylamine derivative is administered is an eukaryotic cell. The hydroxylamine derivative corresponds to the formulae (I) or (II). | 10-21-2010 |
László Korányi, Budapest HU
| Patent application number | Description | Published |
|---|---|---|
| 20100267711 | METHOD OF ENHANCING CELLULAR PRODUCTION OF MOLECULAR CHAPERONE, HYDROXYLAMINE DERIVATIVES USEFUL FOR ENHANCING THE CHAPERONE PRODUCTION AND THE PREPARATION THEREOF - A method of increasing expression of a molecular chaperon by a cell and/or enhancing the activity of a molecular chaperon in cells is provided. The method comprises treating a cell that is exposed to a physiological stress which induces expression of a molecular chaperon by the cell with an effective amount of a certain hydroxylamine derivative to increase the stress. Alternatively, an hydroxylamine derivative can be administrated to a cell before it is exposed to a physiological stress which induces expression of a molecular chaperon by the cell. Preferably, the cell to which an hydroxylamine derivative is administered is an eukaryotic cell. The hydroxylamine derivative corresponds to the formulae (I) or (II). | 10-21-2010 |
László Korányi, Budapest HU
| Patent application number | Description | Published |
|---|---|---|
| 20100267711 | METHOD OF ENHANCING CELLULAR PRODUCTION OF MOLECULAR CHAPERONE, HYDROXYLAMINE DERIVATIVES USEFUL FOR ENHANCING THE CHAPERONE PRODUCTION AND THE PREPARATION THEREOF - A method of increasing expression of a molecular chaperon by a cell and/or enhancing the activity of a molecular chaperon in cells is provided. The method comprises treating a cell that is exposed to a physiological stress which induces expression of a molecular chaperon by the cell with an effective amount of a certain hydroxylamine derivative to increase the stress. Alternatively, an hydroxylamine derivative can be administrated to a cell before it is exposed to a physiological stress which induces expression of a molecular chaperon by the cell. Preferably, the cell to which an hydroxylamine derivative is administered is an eukaryotic cell. The hydroxylamine derivative corresponds to the formulae (I) or (II). | 10-21-2010 |
László Makai, Tamasi HU
| Patent application number | Description | Published |
|---|---|---|
| 20110084589 | VIBRATION RESISTANT ELECTRIC INCANDESCENT LAMP AND METHOD FOR REDUCING VIBRATION - An electric incandescent lamp comprising at least one incandescent filament is provided. The incandescent filament is arranged inside a translucent envelope. The lamp also comprises support wires that protrude out of a stem. The filament has end portions, and each end portion is fixed to a corresponding support wire at a junction point. At least one of the support wires comprises at least one narrowed portion for reducing vibration. The narrowed portions are disposed between the junction point and the stem. In an exemplary embodiment of another aspect of this invention, at least one of the support wires has a second section overhanging beyond the junction point of the end portion of the filament. The at least one narrowed portion for reducing vibration is comprised by the second section. A method for reducing vibration is also disclosed. This method comprises a step of forming at least one narrowed portion in at least one of the support wires. | 04-14-2011 |
László Makai, Tamasi HU
| Patent application number | Description | Published |
|---|---|---|
| 20110084589 | VIBRATION RESISTANT ELECTRIC INCANDESCENT LAMP AND METHOD FOR REDUCING VIBRATION - An electric incandescent lamp comprising at least one incandescent filament is provided. The incandescent filament is arranged inside a translucent envelope. The lamp also comprises support wires that protrude out of a stem. The filament has end portions, and each end portion is fixed to a corresponding support wire at a junction point. At least one of the support wires comprises at least one narrowed portion for reducing vibration. The narrowed portions are disposed between the junction point and the stem. In an exemplary embodiment of another aspect of this invention, at least one of the support wires has a second section overhanging beyond the junction point of the end portion of the filament. The at least one narrowed portion for reducing vibration is comprised by the second section. A method for reducing vibration is also disclosed. This method comprises a step of forming at least one narrowed portion in at least one of the support wires. | 04-14-2011 |
László Nacsa, Algyo HU
| Patent application number | Description | Published |
|---|---|---|
| 20110068572 | SWAGED COUPLING FOR HIGH-PRESSURE HOSE, HIGH-PRESSURE HOSE WITH SWAGED COUPLING, AND METHOD FOR MAKING THE SAME - A hose coupling for high-pressure hoses includes a stem and a ridged outer ferrule connected to the stem, wherein a staggered portion is disposed on the stem in the proximity of the connection of the stem and the ridged outer ferrule, where the diameter of the staggered portion is larger than the diameter of the stem, and the staggered portion has an undercut and a cutting edge. Also, a high-pressure hose fitted with the above swaged coupling, and a method for producing it. In the method, prior to swaging, the cover of the hose is removed at the portion where the cover is in connection with the ridges of the ridged outer ferrule of the hose coupling, and the hose liner and an optionally included load distribution textile ply or cord fabric ply are also removed from the hose end before swaging at a length not longer than the length of the staggered portion of the stem. | 03-24-2011 |
László Nacsa, Algyo HU
| Patent application number | Description | Published |
|---|---|---|
| 20110068572 | SWAGED COUPLING FOR HIGH-PRESSURE HOSE, HIGH-PRESSURE HOSE WITH SWAGED COUPLING, AND METHOD FOR MAKING THE SAME - A hose coupling for high-pressure hoses includes a stem and a ridged outer ferrule connected to the stem, wherein a staggered portion is disposed on the stem in the proximity of the connection of the stem and the ridged outer ferrule, where the diameter of the staggered portion is larger than the diameter of the stem, and the staggered portion has an undercut and a cutting edge. Also, a high-pressure hose fitted with the above swaged coupling, and a method for producing it. In the method, prior to swaging, the cover of the hose is removed at the portion where the cover is in connection with the ridges of the ridged outer ferrule of the hose coupling, and the hose liner and an optionally included load distribution textile ply or cord fabric ply are also removed from the hose end before swaging at a length not longer than the length of the staggered portion of the stem. | 03-24-2011 |
László Nyirö, Nagykovacsi HU
| Patent application number | Description | Published |
|---|---|---|
| 20110272844 | METHOD FOR PRODUCTION OF BUILDING MATERIALS AND BUILDING PRODUCTS MANUFACTURED THEREBY - A method for the production of an additive for building materials, wherein a hidrophobization agent is mixed with a solvent and the resulting emulsion is applied to quicklime, and then the material obtained is hydrated by adding water, wherein the hidrophobization agent is an oil having a dry matter content of 3 to 50% by weight, the quicklime in a quantity of 60 to 96% by weight is soaked with a quantity of 4 to 40% by weight of the mixture of the oil and the solvent, and after dying of the hydrated material a foaming agent is admixed thereto in a quantity of 0.25 to 0.6 part by weight of the foaming agent, preferably sodium bicarbonate, to one part by weight of the hydrated material. By using this additive, a binder comprising an additive is produced so that a hydraulic binding component and/or an isocyanate based binding component are/is added to the additive in a quantity of 4.8 to 14.8 parts by weight of the binding component to one part by weight of the additive. By using the binder comprising an additive, a building material is produced so that an expansion material is added to the binder comprising an additive in a proportion of 2 to 12 units by volume of the expansion material to one unit by volume of the binder comprising an additive, and the material obtained is mixed with added water to a homogenous consistency, then left or made to solidify. The building material according to the invention is preferably a heat-insulating plaster or lightweight concrete, or it can be a heat-insulating building element ( | 11-10-2011 |
László Örfi, Budapest HU
| Patent application number | Description | Published |
|---|---|---|
| 20080207677 | Napthyridine Compounds As Rock Inhibitors - The present invention relates to compounds having a naphthyridine scaffold, and stereoisomeric forms, prodrugs, solvates, hydrates and/or pharmaceutically acceptable salts of these compounds as well as pharmaceutical compositions containing at least one of these naphthyridine derivatives together with pharmaceutically acceptable carrier, excipient and/or diluents. Said naphthyridine compounds have been identified as inhibitors of the protein kinase ROCK2, also known as Rho-kinase, and are useful for the treatment of cancers (tumor growth and metastases), erectile dysfunction, cardiovascular diseases, hypertension, angina pectoris, cerebral ischaemia, cerebral vasospasm, myocardial ischaemia, coronary vasospasm, heart failure, myocardial hypertrophy, atherosclerosis, restenosis, spinal cord injuries, neuronal degeneration, thrombotic disorders, asthma, glaucoma, inflammation, anti-viral diseases (e.g. HIV), and osteoporosis. | 08-28-2008 |
| 20080214583 | 7H-Pyrrolo[2,3-D]Pyrimidine Derivatives, As Well As Their Therapeutically Acceptable Salts, Pharmaceutical Preparations Containing Them And Process For Production The Active Agent - The invention relates to new 7H-pyrrolo[2,3-d]pyrimidine derivatives, as well as their therapeutically acceptable salts, pharmaceutical preparations containing them and process for producing the active agent. The pharmaceutical preparation is adventageously antiphlogistic and analgetic one, a preparation reducing neuropathic hyperalgesia and rheumatic arthritis, a preparation for hindering destruction of bones chondrus, being applicable for treatment of other diseases, which may be connected with other inflammatory processes e.g. asthma, eczema or psoriasis. | 09-04-2008 |
| 20090018149 | 4,5,6,7-tetrahydrobenzo[b]thiophene derivatives and methods for medical intervention against mycobacterial infections - Described are 4,5,6,7-tetrahydrobenzo[b]thiophene derivatives and pharmaceutically acceptable salts thereof, the use of these derivatives for the prophylaxis and/or treatment of mycobacteria-induced infections and opportunistic infections, as well as compositions containing at least one 4,5,6,7-tetrahydrobenzo[b]thiophene derivative and/or pharmaceutically acceptable salts thereof. Furthermore, the present application refers to the use of mycobacterial protein serine/threonine kinases for developing methods for detection and determination of these kinases for recognising and monitoring diseases and for controlling therapy of diseases. | 01-15-2009 |
| 20090298842 | Novel therapeutic targets for the treatment of mycobacterial infections and compounds useful therefor - Described herein is the discovery that certain mycobacterial serine/threonine protein kinases, particularly protein kinase G (PknG), are effective therapeutic targets for the treatment of mycobacterial infections. Furthermore, the present application refers to the use of mycobacterial serine/threonine protein kinases for developing methods for detection and determination of these kinases for recognizing and monitoring diseases and for controlling therapy of diseases. Additionally disclosed are novel 4,5,6,7-tetrahydrobenzo[b]thiophene compounds, benzo(g)quinoxaline compounds, and pharmaceutically acceptable salts thereof, and methods of using such compounds and salts thereof for the prophylaxis and/or treatment of virally and/or bacterially induced infections, particularly mycobacteria-induced infections, including opportunistic infections, as well as pharmaceutical compositions containing at least one 4,5,6,7-tetrahydrobenzo[b]thiophene compound and/or benzo(g)quinoxaline compound and/or pharmaceutically acceptable salts thereof in a pharmaceutically acceptable carrier. | 12-03-2009 |
| 20110015214 | TRICYCLIC BENZO[4,5]THIENO-[2,3-D]PYRIMIDINE-4-YL-AMIN DERIVATIVES, THEIR SALTS, PROCESS FOR PRODUCING THE COMPOUNDS AND THEIR PHARMACEUTICAL USE - The invention relates to novel tricyclic benzo[4,5]thieno-[2,3-d]pyrimidine-4-yl-amin derivatives, as well as their pharmaceutically acceptable salts. The subject of the invention too the process for producing the compounds and their use as a pharmaceutically active agent and as pharmaceutical compositions for prophylaxis and/or treatment of proliferative diseases such as cancer. | 01-20-2011 |
| 20110092503 | QUINOLINE DERIVATIVES AS AXL KINASE INHIBITORS - Novel compounds which are inhibitors of receptor tyrosine kinases of the AXL receptor family are described herein. These compounds are suitable for the treatment or prevention of disorders associated with, accompanied by or caused by hyperfunction of a receptor of the AXL family. The compounds are suitable for the treatment of hyperproliferative disorders, such as cancer, particularly cancer metastases. | 04-21-2011 |
László Örfi, Budapest HU
| Patent application number | Description | Published |
|---|---|---|
| 20090298842 | Novel therapeutic targets for the treatment of mycobacterial infections and compounds useful therefor - Described herein is the discovery that certain mycobacterial serine/threonine protein kinases, particularly protein kinase G (PknG), are effective therapeutic targets for the treatment of mycobacterial infections. Furthermore, the present application refers to the use of mycobacterial serine/threonine protein kinases for developing methods for detection and determination of these kinases for recognizing and monitoring diseases and for controlling therapy of diseases. Additionally disclosed are novel 4,5,6,7-tetrahydrobenzo[b]thiophene compounds, benzo(g)quinoxaline compounds, and pharmaceutically acceptable salts thereof, and methods of using such compounds and salts thereof for the prophylaxis and/or treatment of virally and/or bacterially induced infections, particularly mycobacteria-induced infections, including opportunistic infections, as well as pharmaceutical compositions containing at least one 4,5,6,7-tetrahydrobenzo[b]thiophene compound and/or benzo(g)quinoxaline compound and/or pharmaceutically acceptable salts thereof in a pharmaceutically acceptable carrier. | 12-03-2009 |
| 20110015214 | TRICYCLIC BENZO[4,5]THIENO-[2,3-D]PYRIMIDINE-4-YL-AMIN DERIVATIVES, THEIR SALTS, PROCESS FOR PRODUCING THE COMPOUNDS AND THEIR PHARMACEUTICAL USE - The invention relates to novel tricyclic benzo[4,5]thieno-[2,3-d]pyrimidine-4-yl-amin derivatives, as well as their pharmaceutically acceptable salts. The subject of the invention too the process for producing the compounds and their use as a pharmaceutically active agent and as pharmaceutical compositions for prophylaxis and/or treatment of proliferative diseases such as cancer. | 01-20-2011 |
| 20110092503 | QUINOLINE DERIVATIVES AS AXL KINASE INHIBITORS - Novel compounds which are inhibitors of receptor tyrosine kinases of the AXL receptor family are described herein. These compounds are suitable for the treatment or prevention of disorders associated with, accompanied by or caused by hyperfunction of a receptor of the AXL family. The compounds are suitable for the treatment of hyperproliferative disorders, such as cancer, particularly cancer metastases. | 04-21-2011 |
| 20110318409 | FRACTIONS OF WHEAT GERM FERMENT - The invention concerns wheat germ ferment, its biologically active fractions, the process for their production, the pharmaceutical preparations containing them and their uses. | 12-29-2011 |
László Rovó, Szeged HU
| Patent application number | Description | Published |
|---|---|---|
| 20100297648 | METHOD FOR DIAGNOSING SUSCEPTIBILITY TO POST-TRAUMATIC SCAR-TISSUE FORMATION - Disclosed is an in vitro method for diagnosing susceptibility to post-traumatic scar tissue formation, wherein from a biological sample of a patient the nucleotide of the -509 position of the TGF-β1 gene is determined and if said -509 position contains exclusively C, thus it is the homozygotic wild type allele, then said patient is considered to be susceptible to post-traumatic scar tissue formation. The invention relates furthermore to diagnostic kits for the detection of susceptibility to post-traumatic scar tissue formation, preferably for the detection of susceptibility to tracheal stenosis from a biological sample. | 11-25-2010 |
László Rovó, Szeged HU
| Patent application number | Description | Published |
|---|---|---|
| 20100297648 | METHOD FOR DIAGNOSING SUSCEPTIBILITY TO POST-TRAUMATIC SCAR-TISSUE FORMATION - Disclosed is an in vitro method for diagnosing susceptibility to post-traumatic scar tissue formation, wherein from a biological sample of a patient the nucleotide of the -509 position of the TGF-β1 gene is determined and if said -509 position contains exclusively C, thus it is the homozygotic wild type allele, then said patient is considered to be susceptible to post-traumatic scar tissue formation. The invention relates furthermore to diagnostic kits for the detection of susceptibility to post-traumatic scar tissue formation, preferably for the detection of susceptibility to tracheal stenosis from a biological sample. | 11-25-2010 |
László Solymosi, Erd HU
| Patent application number | Description | Published |
|---|---|---|
| 20110061264 | FOOTWEAR WITH UNSTABLE SOLE STRUCTURE - Footwear with unstable sole structure for statically optimal body posture and healthy dynamics comprising an upper and a sole structure attached to the upper, the sole structure having a wearing layer contacting the ground, a bottom layer attached to the wearing layer, an upper layer attached to the bottom layer, and a stiffener plate contacting the upper layer. A bottom layer covering the tread surface is attached to the wearing layer extending at least over the side surfaces of the bottom layer, An upper layer covering the tread surface is attached to the bottom layer, the upper layer comprising a support projection dimensioned to at least match the print of the arch of the foot, with the material of the bottom layer being more resilient than that of the upper layer. The stiffener plate contacting the upper layer covers the tread surface with a cross-section decreasing towards the toes. | 03-17-2011 |
László Solymosi, Erd HU
| Patent application number | Description | Published |
|---|---|---|
| 20110061264 | FOOTWEAR WITH UNSTABLE SOLE STRUCTURE - Footwear with unstable sole structure for statically optimal body posture and healthy dynamics comprising an upper and a sole structure attached to the upper, the sole structure having a wearing layer contacting the ground, a bottom layer attached to the wearing layer, an upper layer attached to the bottom layer, and a stiffener plate contacting the upper layer. A bottom layer covering the tread surface is attached to the wearing layer extending at least over the side surfaces of the bottom layer, An upper layer covering the tread surface is attached to the bottom layer, the upper layer comprising a support projection dimensioned to at least match the print of the arch of the foot, with the material of the bottom layer being more resilient than that of the upper layer. The stiffener plate contacting the upper layer covers the tread surface with a cross-section decreasing towards the toes. | 03-17-2011 |
László Soós, Budapest HU
| Patent application number | Description | Published |
|---|---|---|
| 20110107550 | Vacuum Cleaner - A vacuum cleaner having a main body and a dust collecting bin, the dust collecting bin is removably mounted in a mounting portion of the main body. | 05-12-2011 |
László Szilák, Szeged HU
| Patent application number | Description | Published |
|---|---|---|
| 20090305329 | INTRACELLULAR TARGETING OF MOLECULES - The present invention provides methods for intracellular and/or nuclear targeting of an agent capable of specifically binding to syndecan-4. The present invention further provides methods for the modification of the intracellular and/or nuclear targeting of said agent, as well methods for identifying compounds capable of modifying the syndecan-4 delivery pathway. The present invention further provides experimental kits to perform the methods according to the invention. | 12-10-2009 |
László Szilák, Szeged HU
| Patent application number | Description | Published |
|---|---|---|
| 20090305329 | INTRACELLULAR TARGETING OF MOLECULES - The present invention provides methods for intracellular and/or nuclear targeting of an agent capable of specifically binding to syndecan-4. The present invention further provides methods for the modification of the intracellular and/or nuclear targeting of said agent, as well methods for identifying compounds capable of modifying the syndecan-4 delivery pathway. The present invention further provides experimental kits to perform the methods according to the invention. | 12-10-2009 |
| 20110124572 | SYNDECAN-4 IS A REGULATOR OF RAC1-GTP - The present invention provides a method for modulating the activity of Rac1, comprising modifying the phosphorylation state of Ser179 in syndecan-4 through influencing the interaction between syndecan-4 and the guanin nucleotide exchange factor of Rac1 (RacGEF) named Tiam1 in a GTP-dependent manner. In particular, methods are provided for enhancing the epithelial phenotype of a cell and for initiating the polarization of a cell by increasing the de-phosphorylation of said Ser179 of syndecan-4, and for enhancing the migratory phenotype of a cell and for initiating the neuronal differentiation of a cell by increasing the phosphorylation of said Ser179 of syndecan-4. Polypeptides for use in modulating the activity of the small GTPase Rac are also provided, as well as a method for identifying an agent capable of indirectly modulating the activity of the small GTPase Rac 1. | 05-26-2011 |
László Tabár, Cave Creek, AZ US
| Patent application number | Description | Published |
|---|---|---|
| 20090185732 | USER INTERFACE AND VIEWING WORKFLOW FOR MAMMOGRAPHY WORKSTATION - This invention provides a simple user interface and sequencing viewing method for a mammography interpretation workstation. In particular, the invention includes the method and apparatus that moves the source images and the associated data using two-level of pre-fetching and caching mechanism, sequences the reading workflow (including worklist, hanging protocol, viewing sequencing), draws markup using electronic grease pan, and automatically generates the recall forms and screening reports. The user interface operates on single button and mouse wheel style to maximize the radiologists' efficiency. | 07-23-2009 |
László Terdy, Budapest HU
| Patent application number | Description | Published |
|---|---|---|
| 20100137622 | INDUSTRIAL METHOD FOR THE SYNTHESIS OF 17-ACETOXY-11beta-[4-(DIMETHYLAMINO)-PHENYL]-21-METHOXY-19-NORPREGNA-4,9-- DIEN-3,20-DIONE AND THE KEY INTERMEDIATES OF THE PROCESS - The present invention relates to a process for the synthesis of the known 17-acetoxy-11-β-[4-(dimethyl amino)-phenyl]-21-methoxy-19-norpregna-4,9-dien-3,20-dione (further on CDB-4124) of formula (I) from 3,3-[1,2-ethandiyl-bis(oxy)]-oestr-5(10),9(11)-dien-17-one of formula (II). Compound CDB-4124 belongs to the group of anti-hormones. The process has the following steps: i) formation of an epoxide; ii) addition of hydrogen cyanide; iii) silylation of a hydroxyl group; iv) reaction with 4-(dimethylamino)-phenyl magnesium bromide Grignard reagent in the presence of CuCl (Teutsch reaction); v) silylation of a hydroxyl group with trimethyl chlorosilane; vi) reaction with diisobutyl aluminum hydride and after addition of acid to the reaction mixture; vii) methoxy-methylation with methoxy-methyl Grignard reagent formed in situ, while hydrolyzing the trimethylsilyl protective groups; viii) oxidation of a hydroxyl group with dicyclohexyl carbodiimide in the presence of dimethyl sulfoxide and a strong organic acid (Swern oxidation), and in given case after purification by chromatography; ix) acetylation of a hydroxyl group with acetic anhydride in the presence of perchloric acid, and in given case, purification by chromatography. The invention also relates to new intermediates of the process. | 06-03-2010 |
László Terdy, Budapest HU
| Patent application number | Description | Published |
|---|---|---|
| 20100137622 | INDUSTRIAL METHOD FOR THE SYNTHESIS OF 17-ACETOXY-11beta-[4-(DIMETHYLAMINO)-PHENYL]-21-METHOXY-19-NORPREGNA-4,9-- DIEN-3,20-DIONE AND THE KEY INTERMEDIATES OF THE PROCESS - The present invention relates to a process for the synthesis of the known 17-acetoxy-11-β-[4-(dimethyl amino)-phenyl]-21-methoxy-19-norpregna-4,9-dien-3,20-dione (further on CDB-4124) of formula (I) from 3,3-[1,2-ethandiyl-bis(oxy)]-oestr-5(10),9(11)-dien-17-one of formula (II). Compound CDB-4124 belongs to the group of anti-hormones. The process has the following steps: i) formation of an epoxide; ii) addition of hydrogen cyanide; iii) silylation of a hydroxyl group; iv) reaction with 4-(dimethylamino)-phenyl magnesium bromide Grignard reagent in the presence of CuCl (Teutsch reaction); v) silylation of a hydroxyl group with trimethyl chlorosilane; vi) reaction with diisobutyl aluminum hydride and after addition of acid to the reaction mixture; vii) methoxy-methylation with methoxy-methyl Grignard reagent formed in situ, while hydrolyzing the trimethylsilyl protective groups; viii) oxidation of a hydroxyl group with dicyclohexyl carbodiimide in the presence of dimethyl sulfoxide and a strong organic acid (Swern oxidation), and in given case after purification by chromatography; ix) acetylation of a hydroxyl group with acetic anhydride in the presence of perchloric acid, and in given case, purification by chromatography. The invention also relates to new intermediates of the process. | 06-03-2010 |
László Ürge, Budapest HU
| Patent application number | Description | Published |
|---|---|---|
| 20110034704 | LABORATORY SCALE CONTINUOUS FLOW HYDROGENATION PROCESS - A process for hydrogenating a sample in a pressure range below supercritical pressure values includes supplying at least a solvent of the sample to be hydrogenated by a feed pump with a constant volume rate into a flow path to create a base solution; adding the sample being dissolved into the flow path; feeding hydrogen into the flow path through a valve configured to transmit hydrogen only into a single direction; leading the dissolved sample in the presence of a catalyst through a hydrogenation reactor, where the reactor is inserted into a section of the flow path located after the hydrogen feeding position; maintaining the pressure of the reaction in a given pressure range by element of a pressure-adjusting unit, and collecting a hydrogenate formed within the hydrogenation reactor in a product receptacle connected to the end of the flow path. | 02-10-2011 |
László Ürge, Budapest HU
| Patent application number | Description | Published |
|---|---|---|
| 20090101519 | FLOW-TYPE LABORATORY OZONOLYSIS APPARATUS AND METHOD OF PERFORMING OZONOLYSIS REACTION - A flow-type laboratory scale ozonolysis apparatus ( | 04-23-2009 |
| 20110034704 | LABORATORY SCALE CONTINUOUS FLOW HYDROGENATION PROCESS - A process for hydrogenating a sample in a pressure range below supercritical pressure values includes supplying at least a solvent of the sample to be hydrogenated by a feed pump with a constant volume rate into a flow path to create a base solution; adding the sample being dissolved into the flow path; feeding hydrogen into the flow path through a valve configured to transmit hydrogen only into a single direction; leading the dissolved sample in the presence of a catalyst through a hydrogenation reactor, where the reactor is inserted into a section of the flow path located after the hydrogen feeding position; maintaining the pressure of the reaction in a given pressure range by element of a pressure-adjusting unit, and collecting a hydrogenate formed within the hydrogenation reactor in a product receptacle connected to the end of the flow path. | 02-10-2011 |
László Ürögdi, Budapest HU
| Patent application number | Description | Published |
|---|---|---|
| 20100267711 | METHOD OF ENHANCING CELLULAR PRODUCTION OF MOLECULAR CHAPERONE, HYDROXYLAMINE DERIVATIVES USEFUL FOR ENHANCING THE CHAPERONE PRODUCTION AND THE PREPARATION THEREOF - A method of increasing expression of a molecular chaperon by a cell and/or enhancing the activity of a molecular chaperon in cells is provided. The method comprises treating a cell that is exposed to a physiological stress which induces expression of a molecular chaperon by the cell with an effective amount of a certain hydroxylamine derivative to increase the stress. Alternatively, an hydroxylamine derivative can be administrated to a cell before it is exposed to a physiological stress which induces expression of a molecular chaperon by the cell. Preferably, the cell to which an hydroxylamine derivative is administered is an eukaryotic cell. The hydroxylamine derivative corresponds to the formulae (I) or (II). | 10-21-2010 |
| 20110021509 | PDE10 INHIBITORS AND RELATED COMPOSITIONS AND METHODS - Compounds that inhibit PDE10 are disclosed that have utility in the treatment of a variety of conditions, including (but not limited to) psychotic, anxiety, movement disorders and/or neurological disorders such as Parkinson's disease, Huntington's disease, Alzheimer's disease, encephalitis, phobias, epilepsy, aphasia, Bell's palsy, cerebral palsy, sleep disorders, pain, Tourette syndrome, schizophrenia, delusional disorders, drug-induced psychosis and panic and obsessive-compulsive disorders. The compounds have the general structure: | 01-27-2011 |
László Ürögdi, Budapest HU
| Patent application number | Description | Published |
|---|---|---|
| 20080300240 | PDE10 INHIBITORS AND RELATED COMPOSITIONS AND METHODS - Compounds that inhibit PDE10 are disclosed that have utility in the treatment of a variety of conditions, including (but not limited to) psychotic, anxiety, movement disorders and/or neurological disorders such as Parkinson's disease, Huntington's disease, Alzheimer's disease, encephalitis, phobias, epilepsy, aphasia, Bell's palsy, cerebral palsy, sleep disorders, pain, Tourette syndrome, schizophrenia, delusional disorders, drug-induced psychosis and panic and obsessive-compulsive disorders. The compounds have the general structure: | 12-04-2008 |
| 20090075993 | Pharmaceutically effective compounds - The subject invention relates to carboxamidine derivatives, to pharmaceutical compositions comprising the same, and the use thereof in the preparation of pharmaceutical compositions for the treatment of vascular diseases. | 03-19-2009 |
| 20090253690 | PHARMACEUTICALLY EFFECTIVE COMPOUNDS - The subject invention relates to carboxamidine derivatives, to pharmaceutical compositions containing the carboxamidine derivatives of the invention, and the use thereof for the treatment of vascular diseases and in the preparation of pharmaceutical compositions for the treatment of vascular diseases. | 10-08-2009 |
| 20100267711 | METHOD OF ENHANCING CELLULAR PRODUCTION OF MOLECULAR CHAPERONE, HYDROXYLAMINE DERIVATIVES USEFUL FOR ENHANCING THE CHAPERONE PRODUCTION AND THE PREPARATION THEREOF - A method of increasing expression of a molecular chaperon by a cell and/or enhancing the activity of a molecular chaperon in cells is provided. The method comprises treating a cell that is exposed to a physiological stress which induces expression of a molecular chaperon by the cell with an effective amount of a certain hydroxylamine derivative to increase the stress. Alternatively, an hydroxylamine derivative can be administrated to a cell before it is exposed to a physiological stress which induces expression of a molecular chaperon by the cell. Preferably, the cell to which an hydroxylamine derivative is administered is an eukaryotic cell. The hydroxylamine derivative corresponds to the formulae (I) or (II). | 10-21-2010 |
| 20110021509 | PDE10 INHIBITORS AND RELATED COMPOSITIONS AND METHODS - Compounds that inhibit PDE10 are disclosed that have utility in the treatment of a variety of conditions, including (but not limited to) psychotic, anxiety, movement disorders and/or neurological disorders such as Parkinson's disease, Huntington's disease, Alzheimer's disease, encephalitis, phobias, epilepsy, aphasia, Bell's palsy, cerebral palsy, sleep disorders, pain, Tourette syndrome, schizophrenia, delusional disorders, drug-induced psychosis and panic and obsessive-compulsive disorders. The compounds have the general structure: | 01-27-2011 |
László Vértesy, Eppstein-Vockenhausen DE
| Patent application number | Description | Published |
|---|---|---|
| 20090298904 | NOVEL PEPTIDES FROM ACTINOMADURA NAMIBIENSIS - The disclosure relates to a compound of the formula (I) | 12-03-2009 |
László Vértesy, Eppstein-Vockenhausen DE
| Patent application number | Description | Published |
|---|---|---|
| 20090298904 | NOVEL PEPTIDES FROM ACTINOMADURA NAMIBIENSIS - The disclosure relates to a compound of the formula (I) | 12-03-2009 |
László Vígh, Szeged HU
| Patent application number | Description | Published |
|---|---|---|
| 20090130234 | Composition for the Treatment of Diabetic Periodontitis - The invention refers to the use of an extract of a part of a | 05-21-2009 |
| 20090214677 | Pharmaceutical Composition Containing an Extract of a Solidago Species - An extract of a part of a | 08-27-2009 |
| 20100267711 | METHOD OF ENHANCING CELLULAR PRODUCTION OF MOLECULAR CHAPERONE, HYDROXYLAMINE DERIVATIVES USEFUL FOR ENHANCING THE CHAPERONE PRODUCTION AND THE PREPARATION THEREOF - A method of increasing expression of a molecular chaperon by a cell and/or enhancing the activity of a molecular chaperon in cells is provided. The method comprises treating a cell that is exposed to a physiological stress which induces expression of a molecular chaperon by the cell with an effective amount of a certain hydroxylamine derivative to increase the stress. Alternatively, an hydroxylamine derivative can be administrated to a cell before it is exposed to a physiological stress which induces expression of a molecular chaperon by the cell. Preferably, the cell to which an hydroxylamine derivative is administered is an eukaryotic cell. The hydroxylamine derivative corresponds to the formulae (I) or (II). | 10-21-2010 |
| 20100311719 | Prevention of Obesity in Antipsychotic, Antidepressant and Antiepileptic Medication - O-(3-piperidino-2-hydroxypropyl)-nicotinic amidoxime or a pharmaceutically suitable acid addition salt thereof (BGP-15) can be used for the prevention or reduction of weight gain or obesity in a patient treated with an antipsychotic drug or an antidepressant drug or an antiepileptic drug. | 12-09-2010 |
László Vígh, Szeged HU
| Patent application number | Description | Published |
|---|---|---|
| 20100267711 | METHOD OF ENHANCING CELLULAR PRODUCTION OF MOLECULAR CHAPERONE, HYDROXYLAMINE DERIVATIVES USEFUL FOR ENHANCING THE CHAPERONE PRODUCTION AND THE PREPARATION THEREOF - A method of increasing expression of a molecular chaperon by a cell and/or enhancing the activity of a molecular chaperon in cells is provided. The method comprises treating a cell that is exposed to a physiological stress which induces expression of a molecular chaperon by the cell with an effective amount of a certain hydroxylamine derivative to increase the stress. Alternatively, an hydroxylamine derivative can be administrated to a cell before it is exposed to a physiological stress which induces expression of a molecular chaperon by the cell. Preferably, the cell to which an hydroxylamine derivative is administered is an eukaryotic cell. The hydroxylamine derivative corresponds to the formulae (I) or (II). | 10-21-2010 |
| 20100311719 | Prevention of Obesity in Antipsychotic, Antidepressant and Antiepileptic Medication - O-(3-piperidino-2-hydroxypropyl)-nicotinic amidoxime or a pharmaceutically suitable acid addition salt thereof (BGP-15) can be used for the prevention or reduction of weight gain or obesity in a patient treated with an antipsychotic drug or an antidepressant drug or an antiepileptic drug. | 12-09-2010 |