Patent application number | Description | Published |
20090269384 | BIOACTIVE THERMOGELLING POLYMER SYSTEMS AND METHODS OF THEIR USE - Hydrogels comprising poly(N-alkylacrylamide), poly(alkyleneglyco)di-acrylate or methacrylate, cross-linking agent, a source of calcium ions, and water are described, as well as methods of their preparation and use. | 10-29-2009 |
20090304771 | Local Delivery System for the Chemotherapeutic Drug Paclitaxel - The present invention provides methods for producing a semi-degradable polymeric composite drug delivery device for localized delivery of chemotherapeutic agents to be used in conjunction with total vertebral body replacement surgery that requires placement of a vertebral replacement cage for the treatment of a spinal neoplasm. | 12-10-2009 |
20100047437 | HYDROGEL BALLOON PROSTHESIS FOR NUCLEUS PULPOSUS - A prosthesis for replacing or supplementing a nucleus pulposus of an intervertebral disk is an expandable container having flexible walls, the container being adapted to be inserted into a central cavity of an intervertebral disk through a narrow cannula, and the flexible walls are made from a biocompatible hydrogel. A preferred hydrogel is a cryogel formed from an aqueous solution of poly(vinyl alcohol) and poly(vinyl pyrrolidone). The prosthesis may be prepared by dip-coating a mandrel with an aqueous solution of a hydrogel-forming polymer or mixture of such polymers, gelling the coated solution by chilling, and subjecting the gelled coating to a series of repeated freeze-thaw treatments. In use, the prosthesis is inserted into a central cavity of an intervertebral disk and filled with biocompatible material, e.g., a biocompatible liquid, a biocompatible polymer, and a biocompatible hydrogel, particularly a thermogelling hydrogel. | 02-25-2010 |
20100272672 | CROSSLINKED HYDROGELS - The present invention preferably provides for a method of forming and the resulting solid polymer gel composition comprising polyethylene imine and at least one hydrogen bonding polymer. The composition has a greater viscosity than either of the polyethylene imine or the hydrogen bonding polymer alone and is injectable immediately after mixing of the polyethylene imine and the at least one hydrogen bonding polymer. A method of tissue repair may include mixing about 9.25% (w/w) to about 13.65% (w/w) polyethylene imine and about 18.02% (w/w) to about 26.62% (w/w) polyvinyl alcohol to form an injectable composition; injecting the injectable composition into a cavity within a human body; and allowing the composition to solidify in situ. A kit may include a multi-barrel syringe at least one barrel is loaded with polyethylene imine and at least another barrel is loaded with at least one hydrogen bonding polymer. | 10-28-2010 |
20100286786 | BIOADHESIVE HYDROGELS - A method of forming and the resulting bioadhesive hydrogel composition for repairing or supplementing a nucleus pulposus of an intervertebral disc comprises at least a first component, a second component and a third component, wherein the first component, the second component and the third component are crosslinked. The first component comprises an amine-containing polymer component at a concentration from about 0.1% weight by weight to about 13.65% weight by weight. The second component comprises a hydrophilic polymer or pre-polymer component at a concentration from about 3% weight by weight to about 35% weight by weight. The third component comprises an aldehyde component at a concentration from about 0.1% weight by weight to about 30% weight by weight. A method of repairing or supplementing a nucleus pulposus of an intervertebral disc comprises implanting the bioadhesive hydrogel composition in a patient. | 11-11-2010 |
20110153022 | BALLOON-ASSISTED ANNULUS REPAIR - The present invention is directed to an inflatable annulus repair device ( | 06-23-2011 |
20110270400 | PHASE TRANSITIONING HYDROGELS - A method of forming and the resulting hydrogel composition comprising poly(vinyl alcohol) at a final concentration of about 20% (w/w) to about 65% (w/w) and polyethylene glycol at a final concentration of about 2% (w/w) to about 20% (w/w), wherein the hydrogel composition has a total polymer content, above about 30% (w/w), higher than the total polymer content of a precursor polymer solution formulated prior to the formulation of the hydrogel composition. The hydrogel composition may further comprise poly(vinyl pyrrolidone) at a fmal concentration of about 0.10% (w/w) to about 0.75% (w/w). | 11-03-2011 |
20110288199 | Fiber-Hydrogel Composite for Tissue Replacement - The present invention includes tailored fiber-reinforced hydrogel composites for implantation into a subject. The present invention also includes systems and methods for controlling the relative percent volume of the hydrogel and fibers, cross-linking, fiber orientation, weave and density, such that the material properties of the composite can be controlled and/or customized to match particular tissue types. The composites of the present invention are suitable for repairing or replacing musculoskeletal tissues and/or fibrocartilage, such as the meniscus, ligaments and tendons. | 11-24-2011 |
20130012913 | INJECTABLE CROSS-LINKED HYDROGELS FOR BIOMATERIAL APPLICATIONS - An injectable hydrogel composition comprising: water; and poly(vinyl alcohol) chemically cross-linked with a second polymer to form a cross-linked resin, wherein the second polymer is selected from the group consisting of: a polyhydric alcohol compound, a polyvalent epoxy compound, a polyvalent amine compound, a dialdehyde compound, a diisocyanate compound, and mixtures thereof, wherein the cross-linked resin has a degree of cross-linking of from about 0.0001 mol/mL to about 0.002 mol/mL, and wherein the hydrogel is flowable when heated above its melting point. | 01-10-2013 |
Patent application number | Description | Published |
20110063139 | EXPLOSION PROOF ELECTRO-MECHANICAL JOYSTICK - A joystick comprising a housing, a ball supported and held within the housing, and a joystick handle attached to the ball. The joystick also includes a first device held within the housing, and a second device held within the housing. The joystick also includes a first engagement shaft extending from the first device to the ball, the first engagement shaft having an end adjacent the ball and engaging the ball, and a second engagement shaft extending from the second device to the ball, the second engagement shaft having an end adjacent the ball and engaging the ball. | 03-17-2011 |
20110156470 | CUTTER HEAD CONTAINING ITS MOTORS AND GEARCASE - An apparatus for mining a mineral seam, comprising a motor, and a cutting drum carried on the frame for winning aggregate material from the mineral seam. The cutting drum encloses the motor, and a gear case drivingly connected between the motor and the cutting drum transmits power from the motor to the cutting drum. The gear case is also enclosed within the cutting drum. | 06-30-2011 |
20130192944 | OVERHEAD POWER GRID FOR MOBILE MINING MACHINES - A vehicle is provided that connects to an overhead power structure for powering and guiding the vehicle. The overhead power structure includes a trolley, a track along which the trolley runs, a power source connected to the track, and a cable connected to the trolley and configured to attach to the vehicle moving on a surface. The vehicle includes a chassis and a cable connected to the chassis and configured to mechanically and electrically connect the vehicle to the overhead power structure. The chassis includes a connector rotatable 360 degrees, and the cable connects to the chassis through the connector. | 08-01-2013 |