| Patent application number | Description | Published |
|---|
| 20080305141 | Freeze-thaw method for modifying stent coating - Methods are disclosed for controlling the morphology and the release-rate of active agent from a coating layer for medical devices comprising a polymer matrix and one or more active agents. The methods comprise exposing a wet or dry coating to a freeze-thaw cycle. The coating layer can be used for controlled delivery of an active agent or a combination of active agents. | 12-11-2008 |
| 20090030505 | Drug eluting implantable medical device with hemocompatible and/or prohealing topcoat - The present invention relates to implantable medical devices coated with polymer having hemocompatible and/or prohealing moieties appended thereto and to their use in the treatment of vascular diseases. | 01-29-2009 |
| 20090036822 | Electrotransport Agent Delivery Method and Apparatus - An electrotransport device for delivering or sampling an agent through a body surface by electrotransport, the device having a housing including an upper, exterior housing portion and a lower housing portion, the housing enclosing electronic components, and at least one hydratable or hydrated reservoir containing water or an at least partially aqueous solution of the agent. At least a portion of the housing is composed of an ethylene-octene copolymer. | 02-05-2009 |
| 20090036978 | Bioabsorbable coating with tunable hydrophobicity - The present invention relates to implantable medical devices coated with polymer having tunable hydrophobicity and their use in the treatment of vascular diseases. | 02-05-2009 |
| 20090297575 | Implantable Drug Delivery Devices Having Alternating Hyrdrophilic And Amphiphilic Polymer Layers - An implantable drug delivery medical device with alternating hydrophilic and amphiphilic polymer layers and methods of using for the treatment of vascular disease are disclosed. | 12-03-2009 |
| 20090297583 | POLY(ESTER AMIDES) FOR THE CONTROL OF AGENT-RELEASE FROM POLYMERIC COMPOSITIONS - The present invention generally encompasses a medical article, such as a medical device or coating comprising an agent or combination of agents, wherein the agent is distributed throughout a polymeric matrix. The polymeric matrix comprises an agent and a poly(ester amide) having a design that was preselected to provide a predetermined release rate of the combination of agents from the medical article. | 12-03-2009 |
| 20090306120 | TERPOLYMERS CONTAINING LACTIDE AND GLYCOLIDE - The present invention provides an amorphous terpolymer for a coating on an implantable device for controlling release of drug and methods of making and using the same. | 12-10-2009 |
| 20090311301 | COATING CONSTRUCT CONTAINING POLY(VINYL ALCOHOL) - A method of forming a surface layer that includes a hydroxyl polymer on a substrate coating on a medical device is provided. | 12-17-2009 |
| 20100025894 | TUBE EXPANSION PROCESS FOR SEMICRYSTALLINE POLYMERS TO MAXIMIZE FRACTURE TOUGHNESS - Methods of fabricating a polymeric stent with improved fracture toughness including radial expansion of a polymer tube along its entire length at the same time and fabricating a stent from the expanded tube are disclosed herein. | 02-04-2010 |
| 20100189758 | COATING CONTAINING PEGYLATED HYALURONIC ACID AND A PEGYLATED NON-HYALURONIC ACID POLYMER - Provided herein are a method, which comprises implanting in a patient an implantable device comprising a coating that includes a PEGylated hyaluronic acid and a PEGylated non-hyaluronic acid biocompatible polymer and the methods of use thereof. | 07-29-2010 |
| 20100191325 | COATING CONTAINING PEGYLATED HYALURONIC ACID AND A PEGYLATED NON-HYALURONIC ACID POLYMER - Provided herein re a composition and a coating or a device (e.g., absorbable stent) that includes a PEGylated hyaluronic acid and a PEGylated non-hyaluronic acid biocompatible polymer and the methods of use thereof. | 07-29-2010 |
| 20100222872 | Methods, Compositions and Devices for Treating Lesioned Sites Using Bioabsorbable Carriers - Methods and compositions for the sustained release of treatment agents to treat an occluded blood vessel and affected tissue and/or organs are disclosed. Porous or non-porous bioabsorbable glass, metal or ceramic bead, rod or fiber particles can be loaded with a treatment agent, and optionally an image-enhancing agent, and coated with a sustained-release coating for delivery to an occluded blood vessel and affected tissue and/or organs by a delivery device. Implantable medical devices manufactured with coatings including the particles or embedded within the medical device are additionally disclosed. | 09-02-2010 |
| 20100252965 | Fabricating An Implantable Medical Device From An Amorphous Or Very Low Crystallinity Polymer Construct - Methods of fabricating a polymeric implantable device with improved fracture toughness through annealing, nucleating agents, or both are disclosed herein. A polymeric construct that is completely amorphous or that has a very low crystallinity is annealed with no or substantially no crystal growth to increase nucleation density. Alternatively, the polymer construct includes nucleating agent. The crystallinity of the polymer construct is increased with a high nucleation density through an increase in temperature, deformation, or both. An implantable medical device, such as a stent, can be fabricated from the polymer construct after the increase in crystallinity. | 10-07-2010 |
| 20100262223 | Stent Formed from Crosslinked Bioabsorbable Polymer and Methods of Making the Stent - A stent having a stent body made from a crosslinked bioabsorbable polymer is disclosed. A method of making the stent including exposing a tube formed from a bioabsorbable polymer to radiation to crosslink the bioabsorbable polymer and forming a stent body from the exposed tube is disclosed. The tube can include a crosslinking agent which induces crosslinking upon radiation exposure. Additionally or alternatively, the bioabsorbable polymer can be a copolymer that crosslinks upon exposure to radiation in the absence of a crosslinking agent. | 10-14-2010 |
| 20100262224 | Stent Made From An Ultra High Molecular Weight Bioabsorbable Polymer With High Fatigue And Fracture Resistance - A stent made from an ultra high molecular weight bioabsorbable polymer is disclosed herein. The bioabsorbable polymer can have a Mw greater than 1 million g/mole or greater than 2 million g/mole. Methods of making the ultra high molecular weight polymer stent without degrading the molecular weight are further disclosed. | 10-14-2010 |
| 20110027188 | Methods, Compositions and Devices for Treating Lesioned Sites Using Bioabsorbable Carriers - An implantable medical device is disclosed having a plurality of smaller particles contained in a plurality of larger particles and configured to be released from the larger particles when the device is implanted in a patient. The smaller particles and the larger particles are made of bioabsorbable metal, glass or ceramic. A substance can be associated with the smaller particles. The larger particles can be embedded within at least a portion of the device. | 02-03-2011 |
| 20110049751 | Method Of Fabricating A Low Crystallinity Poly(L-Lactide) Tube - Methods of fabricating a low crystallinity polymer tube for polymers subject to strain-induced crystallization. The low crystallinity tube may be further processed to make an implantable medical device. | 03-03-2011 |
| 20110144741 | Coating Construct With Enhanced Interfacial Compatibility - The present invention provides a method of forming a coating on a medical device having a topcoat and a basecoat and an improved compatibility between a topcoat and a basecoat on the medical device. | 06-16-2011 |
