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Longo, US
Curtis Longo, Alta Loma, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20080237908 | Vibration apparatus and methods of vibration - The present invention relates to apparatus and methods of vibration. In particular, the present invention relates to apparatus and methods of vibration for tooling in a structure, such as, for example, a fuselage. In one implementation, the tooling comprises at least two conductors that create a force to vibrate the media in the tooling, which improves the compaction of the media in the tooling and the extraction of the media from the tooling. Other implementations may be used for compaction and/or extraction of the media in the tooling. | 10-02-2008 |
Dan Longo, Kensington, MD US
| Patent application number | Description | Published |
|---|---|---|
| 20090068234 | Methods and compositions for the treatment and prevention of cancer - The instant invention provides compositions for the treatment of cancer. Specifically, the invention provides polypeptides and nucleic acid molecules comprising tumor-associated embryonic antigens, e.g., OFA-iLRP, and chemoattractant ligands, e.g., a proinflammatory chemokine such as MIP3α/CCL20 or β-defensin mDF2β. The invention further provides cancer vaccines and methods for treating subjects having, or at risk of developing, cancer. | 03-12-2009 |
Dan L. Longo, Kensington, MD US
| Patent application number | Description | Published |
|---|---|---|
| 20110014204 | Cancer Chemoprevention Strategy Based on Loss of Imprinting of IGF2 - The present invention relates to targets of loss of imprinting (LOI) affected IGF2 gene products in pre-malignant tissues, where methods of inhibiting those targets, including IGFR1, are disclosed to prevent tumor development in subjects at risk for developing colorectal cancer (CRC). The present invention also relates to methods of identifying increased risk in developing CRC in a subject, including methods of assessing the efficacy of a chemotherapeutic regimen. Further, the present invention relates to methods for identifying anti-neoplastic agents. | 01-20-2011 |
Diane Longo, Foster City, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20110262468 | Method for Monitoring Vaccine Response Using Single Cell Network Profiling - The present invention provides methods for determining safety and efficacy of a vaccine by monitoring cellular pathways prior to and after vaccine treatment using single cell network profiling | 10-27-2011 |
Frank M. Longo, Menlo Park, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20100267727 | PHARMACEUTICAL FORMULATIONS COMPRISING NEUROTROPHIN MIMETICS - Methods and compounds for treating neurodegenerative and other disorders. Included is the administering to a subject in need thereof an effective amount of a compound having binding specificity for a p75 | 10-21-2010 |
| 20110003819 | METHODS OF TREATING MULTIPLE SCLEROSIS USING NEUROTROPHIN MIMETICS - Methods and compounds for treating neurodegenerative and other disorders. Included is the administering to a subject in need thereof an effective amount of a compound having binding specificity for a p75 | 01-06-2011 |
| 20110230479 | NEUROTROPHIN MIMETICS AND USES THEREOF - The present application is related to compounds which are novel neurotrophin mimetics. The application also discloses the treatment of disorders associated with p75 expression, such as degradation or dysfunction of cells expressing p75 in a mammal by administering an effective amount of such compounds. | 09-22-2011 |
| 20120004310 | NON-PEPTIDE BDNF NEUROTROPHIN MIMETICS - Methods and compounds for treating neurological and other disorders are provided. Included is the administering to a subject in need thereof an effective amount of a compound having binding and/or modulation specificity for a TrkB receptor molecule. | 01-05-2012 |
Frank N. Longo, East Northport, NY US
| Patent application number | Description | Published |
|---|---|---|
| 20080219944 | Polymer based antifouling coating - A coating composition comprising (i) at least one resin powder and (ii) at least one component selected from the group consisting of a metal compound, biocide and fluoropolymers. In particular, one antifouling composition that can be used on underwater stationary structures that sit in highly fouling environments comprises polyethylene as a resin powder, and copper in the form of cuprous or cupric oxide. | 09-11-2008 |
John M. Longo, Houston, TX US
| Patent application number | Description | Published |
|---|---|---|
| 20090254283 | METHOD FOR PETROPHYSICAL EVALUATION OF SHALE GAS RESERVOIRS - A method for evaluating an earth formation from a well bore, that includes: collecting at least one of geochemical data, petrophysical data and geomechanical data from a wellbore; and identifying depositional facies of the earth surrounding the wellbore. A computer program product and a system are provided. | 10-08-2009 |
| 20100312479 | USE OF CHEMICALLY AND GEOLOGICALLY CONSISTENT CONSTRAINTS FOR OBTAINING ELEMENTAL CHEMISTRY DOWNHOLE - A method for estimating a lithotype of an earth formation, the method includes: obtaining at least two different energy spectra of radiation received from the earth formation using the logging tool, each energy spectrum having at least one of a natural gamma-ray spectrum, a fast neutron-induced inelastic spectrum, and a thermal neutron induced capture spectrum; establishing at least one geochemically-based constraint related to elemental spectral yields to be determined; determining the elemental spectral yields from the at least two different energy spectra by decomposing the at least two different energy spectra over weighted sum of monoelemental standards wherein at least one weight is constrained by the at least one geochemically-based constraint and each weight represents a proportion of one monoelemental standard; converting the elemental spectral yields to elemental concentrations; and using a classifier to receive the elemental concentrations as input and to provide a lithotype as output. | 12-09-2010 |
Joseph Cosimo Longo, Feed Hills, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20100282118 | Chemiluminescent impact activated projectile - The present invention relates to a non-pyrotechnic, self-illuminating projectile useful for marking, target illumination, or targeting adjustment which produces chemiluminescent light upon impact with an object. Because the production of light is delayed until impact, the projectile is not visualized until impact and the intensity of light upon impact is greater than light produced by projectiles that provide intermixing of light generating chemicals during flight. | 11-11-2010 |
Joseph Cosimo Longo, Feeding Hills, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20090103279 | Evacuation station with multiple lightstick activation - A chemiluminescent lightstick evacuation station consisting of a wall mountable fixture that stores a plurality of lightsticks that are accessed by opening the fixture cover. The fixture cover is opened by pivoting from a closed position to an open position wherein a lightstick restraint causes the activation of all stored lightsticks so as to facilitate their removal and use during an emergency. One lightstick may be retained in the device by use of restricted movement housing, and all lightsticks may be made to rotate outwardly for ease of access. | 04-23-2009 |
| 20090175024 | Chemiluminescent tactical illumination baton - A light stick for providing chemiluminescent light to provide general illumination of an otherwise darkened area. The device is thrown into position causing the chemiluminescent components to mix upon impact with a rigid object thereby generating chemiluminescent light after a predetermined delay. The device will provide illumination to an area of possible criminal activity and can be used tactically by law enforcement officials to help avoid danger to themselves and possibly others. | 07-09-2009 |
| 20100097778 | Emergency light station with mechanically activated radio frequency signaling - A signaling system for an emergency light station containing chemiluminescent light sticks. The light station includes a cover that generates mechanical energy upon opening that is then transformed into electrical power. The electrical power is then utilized to transmit a radio frequency signal to a remote location is alert an observer to the fact that the light station has been opened. The alert provides an immediate indication that an emergency is in progress or that the safety emergency light station is being vandalized. | 04-22-2010 |
| 20120020050 | Chemiluminescent grenade - The present invention discloses a non-pyrotechnic, light emitting projectile for marking and illuminating a target. The projectile generally contains a main body having frangible side walls, at least one frangible ampoule containing chemiluminescent reactant components, a substantially incompressible filler material positioned between the frangible side walls and ampoule, and a first and second end cap. The first end cap is designed to be traversable between a first position and a second position upon impact with an object, thus provides a force sufficient to rupture the frangible side walls and ampoules. Rupture of the ampoules causes intermixing of the chemiluminescent reactant components and formation of a chemiluminescent slurry. The second end cap provides sufficient energy transfer to the chemiluminescent slurry upon impact with a target to disperse the chemiluminescent slurry radially and outwardly with respect to the longitudinal axis of the main body. | 01-26-2012 |
Kenneth A. Longo, Ann Arbor, MI US
| Patent application number | Description | Published |
|---|---|---|
| 20090074886 | GSK-3 INHIBITORS - This invention relates to methods of treating or preventing bone loss by administering to a human or animal subject pyrimidine and pyridine derivatives that inhibit the activity of glycogen synthase kinase 3 (GSK3), to pharmaceutical compositions containing the compounds, and to the use of the compounds and compositions alone or in combination with other pharmaceutically active agents. | 03-19-2009 |
Martin D. Longo, Petaluma, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20110106920 | Mapping Network Addresses to Organizations - Network addresses (e.g., IP addresses) are considered candidates for association with organizational entities (organizations or various subgroups thereof), based on some evidence of a relationship between them. The candidate addresses are scored based on one or more factors that indicate a probability that the candidate address actually belongs to the organizational entity. The candidate addresses with sufficient scores are stored as actual associations between the candidate address and the organizational entity. | 05-05-2011 |
Mary Longo, Germantown, MD US
| Patent application number | Description | Published |
|---|---|---|
| 20110108420 | METHODS FOR PRODUCTION OF PROTEINS - The current invention provides methods for producing a polypeptide as inclusion bodies in bacterial host cells. The present methods are carried out by forming a gene construct comprising the genetic sequence encoding a polypeptide operatively linked to that of an inclusion partner protein, such as | 05-12-2011 |
Michael A. Longo, Glenmoore, PA US
| Patent application number | Description | Published |
|---|---|---|
| 20120071965 | IMPLANTABLE GRAFT CONNECTOR - A connector for fluidically connecting a graft to a patient's natural vessel to enable fluid to flow through the graft into the vessel. The connector comprises a main conduit having opposing ends each configured to be implanted in the vessel; and a branch conduit having a first end integral with the main conduit and a second end connectable to the graft, wherein the branch conduit extends at angle from the main conduit at a point between the opposing ends of the main conduit. | 03-22-2012 |
Nathan B. Longo, Calais, VT US
| Patent application number | Description | Published |
|---|---|---|
| 20100170481 | Fog carburetor - A conversion system for a gasoline engine based generator enables the use of heavier fuels. A vertically disposed vortex separation chamber includes an inlet proximate the bottom of the chamber and tangential to the longitudinal axis of the chamber for delivering to the chamber partially vaporized fuel in an air-fuel mixture from a carburetor associated with the engine. An outlet proximate the top of the chamber also tangential to the longitudinal axis of the chamber for delivering vaporized fuel from the chamber to the engine. An electric heater is in communication with the bottom of the chamber for heating the chamber wall to vaporize any fuel thereon so vaporized fuel is reintroduced in swirling air-fuel mixture in the chamber. A battery source charged by the generator provides power to the electric heater. A jacket is disposed about and spaced from the chamber wall creating an annulus between the jacket and the chamber wall. An inlet through the jacket is connected to receive exhaust gas from the engine and to deliver the exhaust gas into the annulus for heating the chamber. | 07-08-2010 |
Peter P. Longo, Hopewell Junction, NY US
| Patent application number | Description | Published |
|---|---|---|
| 20090107964 | DEBRIS MINIMIZATION AND IMPROVED SPATIAL RESOLUTION IN PULSED LASER ABLATION OF MATERIALS - A method of minimizing the deposition of debris onto a sample being ablated. The method comprises: 1) reducing a laser pulse energy to approximately a threshold level for ablation; 2) focusing the energy using an immersion object lens having a final element and 3) ablating a region of the sample using a multitude of laser pulses, each pulse being sufficiently separated in time to reduce a concentration of ablation products in a gas phase. | 04-30-2009 |
| 20100006550 | METHOD FOR MINIMIZING SAMPLE DAMAGE DURING THE ABLATION OF MATERIAL USING A FOCUSED ULTRASHORT PULSED LASER BEAM WHEREIN THE SLOPE OF FLUENCE BREAKDOWN IS A FUNCTION OF THE PULSE WIDTH - In one aspect the invention provides a method for laser induced breakdown of a material with a pulsed laser beam where the material is characterized by a relationship of fluence breakdown threshold (Fth) versus laser beam pulse width (T) that exhibits an abrupt, rapid, and distinct change or at least a clearly detectable and distinct change in slope at a predetermined laser pulse width value. The method comprises generating a beam of laser pulses in which each pulse has a pulse width equal to or less than the predetermined laser pulse width value. The beam is focused above the surface of a material where laser induced breakdown is desired. The region of least confusion (minimum beam waist or average spot size) is above the surface of the material in which laser induced breakdown is desired since the intensity of the beam falls off in the forward direction, preferably the region of the beam at or within the surface is between the region of least confusion and sufficient to remove material and the minimum intensity necessary for laser induced breakdown of the material to be removed, most preferably the region of minimum intensity is disposed at the surface of the material to be removed. The beam may be used in combination with a mask in the beam path. The beam or mask may be moved in the x, y, and Z directions to produce desired features. The technique can produce features smaller than the spot size and Rayleigh range due to enhanced damage threshold accuracy in the short pulse regime. | 01-14-2010 |
| 20100289186 | ENHANCED QUALITY OF LASER ABLATION BY CONTROLLING LASER REPETITION RATE - A method of enhancing the quality of laser ablation by controlling the laser repetition rate during the ablation process, wherein the method enhances the quality of laser ablation of a photomask in order to improve the optical quality thereof. Also provided is a system employing the method of enhancing the quality of laser ablation. | 11-18-2010 |
| 20110110578 | Evaluation of Image Processing Algorithms - One exemplary aspect of this invention pertains to a method to evaluate an image processing algorithm. The method includes varying a parameter of a model of an imaging system and, for each variation of the parameter, calculating with a data processor a corresponding image of a sample; applying an image processing algorithm to the calculated corresponding images of the sample; and determining an ability of the image processing algorithm to detect the variation in the parameter. | 05-12-2011 |
Richard V. Longo, North Kingstown, RI US
| Patent application number | Description | Published |
|---|---|---|
| 20110295283 | SOFT TISSUE REPAIR PROSTHESIS, EXPANDABLE DEVICE, AND METHOD OF SOFT TISSUE REPAIR - A hernia repair device is provided which may include a soft tissue repair prosthesis and an expandable device configured to be removably connected with the soft tissue repair prosthesis. When expanded, the expandable device may be configured to position the soft tissue repair prosthesis adjacent a hernia defect. The soft tissue repair prosthesis may include at least one loop or slit configured to receive a portion of the expandable device. The prosthesis may include a tether to hoist, locate or position the soft tissue repair prosthesis. The expandable device may include indicia for positioning the prosthesis relative to the edge of the hernia defect. | 12-01-2011 |
Sheila A. Longo, Somerville, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20080276408 | AUTONOMOUS COVERAGE ROBOT - A surface treatment robot includes a chassis having forward and rear ends and a drive system carried by the chassis. The drive system includes right and left driven wheels and is configured to maneuver the robot over a cleaning surface. The robot includes a vacuum assembly, a collection volume, a supply volume, an applicator, and a wetting element, each carried by the chassis. The wetting element engages the cleaning surface to distribute a cleaning liquid applied to the surface by the applicator. The wetting element distributes the cleaning liquid along at least a portion of the cleaning surface when the robot is driven in a forward direction. The wetting element is arranged substantially forward of a transverse axis defined by the right and left driven wheels, and the wetting element slidably supports at least about ten percent of the mass of the robot above the cleaning surface. | 11-13-2008 |
| 20080281470 | AUTONOMOUS COVERAGE ROBOT SENSING - An autonomous coverage robot detection system includes an emitter configured to emit a directed beam, a detector configured to detect the directed beam and a controller configured to direct the robot in response to a signal detected by the detector. In some examples, the detection system detects a stasis condition of the robot. In some examples, the detection system detects a wall and can follow the wall in response to the detected signal. | 11-13-2008 |
Stephen Longo, Northport, NY US
| Patent application number | Description | Published |
|---|---|---|
| 20100326370 | Dog leash assembly - A leash assembly designed to attach at least one waste holding device, such as a plastic bag, in such a manner that the plastic bag is able to swivel about and not get tangled as the dog moves from side to side. This eliminates the need of the person walking the dog to constantly move the leash from one hand to the other hand in order to prevent the waste bag from getting tangled. In other words, as the dog move in different directions the waste bag holding device is able to adjust its' position by swiveling about the device attached to the leash allowing the walker to have their hands free. The swivel can also be adapted to hold other items such as keys, extra bags for dog cleanup and hand wipes. All of these items would also be able to swivel about the device. The present invention eliminates the need for the person walking the dog from carrying the waste bag and switching the bag from hand to hand as the dog moves from side to side until a waste receptacle is reached that the waste can be disposed of properly. | 12-30-2010 |
Stephen A. Longo, Dripping Springs, TX US
| Patent application number | Description | Published |
|---|---|---|
| 20100153300 | DERIVATIVE TRADING STRATEGY BACKTESTING MACHINE - An automated information search, retrieval and reporting system, and more particularly, a system designed for the historical backtesting of financial market positions, for example, the simulation of the execution of derivative trading strategies. A user accesses data in a market information database via user interface by submitting queries in a near natural language format that define a desired derivative trading strategy with respect to one or more tradable securities. Historical daily price information about securities and derivatives are gathered and combined in a single location. Derivative relative data is created from the historical information and stored as a continuous historical series, wherein the derivative relative data is derived from each derivative's relative position to the underlying instrument with respect to price and date information. Reports express the results of the simulated execution of the derivative trading strategy that would have resulted from actual execution of the derivative trading strategy in the historical timeframe, including the daily profits and losses. | 06-17-2010 |
Valter Longo, Los Angeles, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20100004309 | Dietary Compositions and Methods for Protection Against Chemotherapy, Radiotherapy, Oxidative Stress, and Aging - The present invention relates to dietary compositions comprising reduced level of methionine, tryptophan, all amino acids, or protein, dietary compositions comprising glycerol as a substitute for monosaccharides, disaccharides, and polysaccharides, and hypocaloric or calorie free diets with reduced level of energy, carbohydrates, or protein. Also disclosed are methods of using these compositions and diets, as well as fasting, to protect subjects against chemotherapy, radiotherapy, oxidative stress, or aging. | 01-07-2010 |
Valter Longo, Playa Del Rey, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20080242638 | INDUCTION OF DIFFERENTIAL STRESS RESISTANCE AND USES THEREOF - This invention relates to methods of inducing differential stress resistance in a subject with cancer by starving the subject for a short term, administering a cell growth inhibitor to the subject, or reducing the caloric or glucose intake by the subject. The induced differential stress resistance results in improved resistance to cytotoxicity in normal cells, which, in turn, reduces cytotoxic side-effects due to chemotherapy, as well as improved effectiveness of chemotherapeutic agents. | 10-02-2008 |
Valter D. Longo, Playa Del Rey, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20110118528 | Methods and Nutritional Formulations to Increase the Efficacy and Reduce the Side Effects of Cancer Treatment - The present invention relates to methods of protecting patients and sensitizing cancer cells in combination with chemotherapy and/or radiation therapy. More specifically, the invention provides nutritional methods and formulations that are capable of reducing cancer growth without causing chronic weight loss in patients, protecting normal cells, tissues and organs from chemotherapy and/radiation therapy, and sensitizing cancer cells against low, normal and high-dose chemotherapy. Some of the methods also impede cancer growth even without chemotherapy. | 05-19-2011 |
William Longo, Mentor, OH US
| Patent application number | Description | Published |
|---|---|---|
| 20110209424 | SELF ADHERING WINDOW FLASHING TAPE WITH MULTI-DIRECTIONAL DRAINAGE PLANE - The disclosure provides a self adhesive, flexible tape for flashing exterior wall openings. The tape is a composite comprising a barrier layer having an exterior surface and an interior surface and an adhesive layer overlying the interior surface. The barrier layer exterior surface is patterned to provide a gravity drainage path in both the tape machine direction (MD) and tape cross machine direction (CD). | 09-01-2011 |