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Liu, PA

Changbao Liu, Radnor, PA US

Patent application numberDescriptionPublished
20090130661Method for Detecting IL-16 Activity and Modulation of IL-16 Activity Based on Phosphorylated Stat-6 Proxy Levels - Methods for detecting IL-16 biological activity, detecting modulation of IL-16 biological activity, and diagnosing the presence of, or susceptibility to, an IL-16-related disorder in a subject involve measuring and comparing the levels of a phosphorylated STAT-6 proxy produced by eukaryotic cells expressing CD4 or CD9, peripheral blood mononuclear cells, HuT-78 cells, or THP-1 cells.05-21-2009

Changbao Liu, Malvern, PA US

Patent application numberDescriptionPublished
20110027294Anti-Respiratory Syncytial Virus Antibodies, Antigens and Uses Thereof - Anti-Respiratory Syncytial Virus (RSV) monoclonal antibodies, RSV F protein antigens and their uses are disclosed.02-03-2011

Changchun Liu, Philadelphia, PA US

Patent application numberDescriptionPublished
20100035349Biodetection Cassette with Automated Actuator - Provided are analysis cassettes that include removable sealing layers and deformable connector layers that place various channels, chambers, and reservoirs on the cassettes into fluid communication with one another. The cassettes are suitable for use in self-contained, immunoassay devices that may be operated in an automated fashion. Also disclosed are methods for analyzing samples by use of the disclosed cassettes.02-11-2010

Changsheng Liu, State College, PA US

Patent application numberDescriptionPublished
20090090630Automated parallel capillary electrophoresis system with hydrodynamic sample injection - An automated capillary zone electrophoretic system is disclosed. The system employs a capillary cartridge having a plurality of capillary tubes. The cartridge has a first array of capillary ends projecting from one side of a plate. The first array of capillary ends is spaced apart in substantially the same manner as the wells of a microtitre tray of standard size. This allows one to simultaneously perform capillary electrophoresis on samples present in each of the wells of the tray. The system includes a stacked, dual carrousel arrangement to eliminate cross-contamination resulting from reuse of the same buffer tray on consecutive executions from electrophoresis. The system also has a container connected to the detection end of the capillaries. The container is provided with valving which facilitate cleaning the capillaries, loading buffer into the capillaries, introducing samples to be electrophoresed into the capillaries, and performing capillary zone electrophoresis on the thus introduced samples.04-09-2009
20090301884Electrophoretic analysis system having in-situ calibration - An electrophoretic system having a plurality of separation lanes is provided with an automatic calibration feature in which each lane is separately calibrated. For each lane, the calibration coefficients map a spectrum of received channel intensities onto values reflective of the relative likelihood of each of a plurality of dyes being present. Individual peaks, reflective of the influence of a single dye, are isolated from among the various sets of detected light intensity spectra, and these can be used to both detect the number of dye components present, and also to establish exemplary vectors for the calibration coefficients which may then be clustered and further processed to arrive at a calibration matrix for the system. The system thus permits one to use different dye sets to tag DNA nucleotides in samples which migrate in separate lanes, and also allows for in-situ calibration with new, previously unused dye sets.12-10-2009
20100116659Multidimensional Separations Employing an Array of Electrophoresis Channels - The present invention relates to a method for separating components of a sample. The method includes obtaining a first separation of the sample components along a first dimension wherein the sample components are at least partially resolved, wherein the first separation can be performed in the absence of an electric field applied to the first dimension. An electric field is used to obtain a second separation of the sample components along a second dimension comprising a plurality of substantially isolated volumes. An intensity-time data record is obtained from each of the isolated volumes, the intensity-time data records containing peaks, each peak being indicative of a migration time. The migration time of a first peak is normalized with respect to a migration time of at least a second peak to correct for migration time differences between the isolated volumes.05-13-2010
20100147692Automated Parallel Capillary Electrophoresis System with Hydrodynamic Sample Injection - An automated capillary zone electrophoretic system is disclosed. The system employs a capillary cartridge having a plurality of capillary tubes. The cartridge has a first array of capillary ends projecting from one side of a plate. The first array of capillary ends is spaced apart in substantially the same manner as the wells of a microtitre tray of standard size. This allows one to simultaneously perform capillary electrophoresis on samples present in each of the wells of the tray. The system includes a stacked, dual carrousel arrangement to eliminate cross-contamination resulting from reuse of the same buffer tray on consecutive executions from electrophoresis. The system also has a container connected to the detection end of the capillaries. The container is provided with valving which facilitate cleaning the capillaries, loading buffer into the capillaries, introducing samples to be electrophoresced into the capillaries, and performing capillary zone electrophoresis on the thus introduced samples.06-17-2010

Patent applications by Changsheng Liu, State College, PA US

Changsheng Jonathan Liu, State College, PA US

Patent application numberDescriptionPublished
20090318310DNA Sequence Assembly Methods of Short Reads - Certain embodiments of the invention provide systems and methods for the automated assembly of DNA sequence data into contiguous DNA segments using a computer a system. DNA sequence data is entered into the system. The system indexes and groups a plurality of DNA fragment reads utilizing an anchor sequence and consolidates the fragments into larger sequences by merging the fragment reads within a group.12-24-2009

Chau-Ching Liu, Pittsburgh, PA US

Patent application numberDescriptionPublished
20090298198DIAGNOSING AND MONITORING INFLAMMATORY DISEASES BY MEASURING COMPLEMENT COMPONENTS ON WHITE BLOOD CELLS - The invention is related to methods of diagnosing inflammatory diseases or conditions by determining levels of components of the complement pathway on the surface of white blood cells.12-03-2009

Chengyang Liu, Philidelphia, PA US

Patent application numberDescriptionPublished
20100272697PANCREATIC ISLET CELLS COMPOSITION AND METHODS - A composition comprising islet cells and an extracellular matrix component as well as methods of transplanting same are described. Retroperitoneal and subcutaneous islet cells transplants maintain their viability and increased insulin production for prolonged periods of time.10-28-2010

Dahui Liu, Wynnewood, PA US

Patent application numberDescriptionPublished
20100081665Anti-Malarial Compounds - The present invention provides tricyclic compounds, arylamide compounds, and other compounds, and compositions comprising the same, for treating malaria, and methods of treating malaria comprising administering such compounds to an animal.04-01-2010
20100105703Synthetic Mimetics Of Host Defense And Uses Thereof - The present invention provides arylamide compounds and methods of making and using them as antibiotics.04-29-2010
20100144761Antimicrobial Molecules For Treating Multi-Drug Resistant And Extensively Drug Resistant Strains Of Mycobacterium - The present invention provides methods of inhibiting the growth of 06-10-2010
20100298344Polycationic Compounds And Uses Thereof - Aspects of the present invention relate to compounds and methods useful in modulating angiogenesis and methods of treating or preventing diseases associated with angiogenesis by administering a polycationic compound. The present invention relates to methods of use and compositions for inhibiting angiogenesis-mediated disorders in mammals including animals and humans. Additionally, this invention relates to the combined use of polycations with other anti-angiogenesis agents for the treatment of different angiogenesis-mediated disorders. Additionally, those polycationic compounds can be used with various anti-inflammatory and cytotoxic agents as well as with radio-therapeutic agents in cancer patients to prevent and treat tumor growth and metastasis.11-25-2010
20110124664Polycationic Compounds And Uses Thereof - Aspects of the present invention relate to compounds and methods useful in modulating angiogenesis and methods of treating or preventing diseases associated with angiogenesis by administering a polycationic compound. The present invention relates to methods of use and compositions for inhibiting angiogenesis-mediated disorders in mammals including animals and humans. Additionally, this invention relates to the combined use of polycations with other anti-angiogenesis agents for the treatment of different angiogenesis-mediated disorders. Additionally, those polycationic compounds can be used with various anti-inflammatory and cytotoxic agents as well as with radio-therapeutic agents in cancer patients to prevent and treat tumor growth and metastasis.05-26-2011

Patent applications by Dahui Liu, Wynnewood, PA US

Dahui Liu, Radnor, PA US

Patent application numberDescriptionPublished
20110098498Processes For Preparing A Polymeric Compound - The present invention provides methods for preparing a polymeric compound of Formula I:04-28-2011
20110178104Anti-Heparin Compounds - The present invention provides compounds and methods for antagonizing the anticoagulant effect of an anticoagulant agent that is selected from UFH, LMWH, and a heparin/LMWH derivative in a patient comprising administering to the patient a compound of the invention or a salt thereof, or a composition comprising the same.07-21-2011

Dan Liu, Washington, PA US

Patent application numberDescriptionPublished
20100153583SYSTEM AND METHOD FOR DELIVERING CUSTOMIZED CONTENT TO MOBILE DEVICES - The illustrative embodiment of the present invention provides a platform that enables a content developer to distribute uniform content to multiple types of requesting mobile devices. By authoring content in a generic markup language and using the technologies included in the Mobile Content Framework (MCF), the content developer is able to provide content to multiple types devices without providing different versions of the content. The content may be authored originally in the generic markup language or translated from other languages into the generic markup language by the MCF. The MCF exploits the capabilities and accommodates the limitations of different types of wireless devices by converting generic markup language content to device-specific content. The MCF interacts with device registries holding records of the device attributes in order to provide the device-specific content. The MCF handles these issues for current mobile devices while also being extensible for future mobile devices.06-17-2010

George Dacai Liu, Collegeville, PA US

Patent application numberDescriptionPublished
20100304999SYSTEM AND METHOD FOR ANTIGEN STRUCTURE-INDEPENDENT DETECTION OF ANTIGENS CAPTURED ON ANTIBODY ARRAYS - The present invention provides a system and method for detecting antigens captured on an antibody array. The method comprises the following steps of providing the antibody array having at least two antibodies, contacting the antibody array with a sample containing at least one antigen that may be captured by the antibodies disposed on the antibody array, and detecting the at least one antigen captured by the antibody array with a detecting agent that specifically binds to the antigen-bound antibodies on the antibody array, thereby the at least one antigen captured by the antibody array can be detected independent of the structures of the antigens. In a preferred embodiment, C1q is used as the detecting agent to detect antigen-bound antibodies.12-02-2010

Guangyu Liu, Bethlehem, PA US

Patent application numberDescriptionPublished
20110133157SURFACE PLASMON DISPERSION ENGINEERING VIA DOUBLE-METALLIC AU/AG LAYERS FOR NITRIDE LIGHT-EMITTING DIODES - A double-metallic deposition process is used whereby adjacent layers of different metals are deposited on a substrate. The surface plasmon frequency of a base layer of a first metal is tuned by the surface plasmon frequency of a second layer of a second metal formed thereon. The amount of tuning is dependent upon the thickness of the metallic layers, and thus tuning can be achieved by varying the thicknesses of one or both of the metallic layers. In a preferred embodiment directed to enhanced LED technology in the green spectrum regime, a double-metallic Au/Ag layer comprising a base layer of gold (Au) followed by a second layer of silver (Ag) formed thereon is deposited on top of InGaN/GaN quantum wells (QWs) on a sapphire/GaN substrate.06-09-2011
20110147702NITRIDE BASED QUANTUM WELL LIGHT-EMITTING DEVICES HAVING IMPROVED CURRENT INJECTION EFFICIENCY - A III-nitride based device provides improved current injection efficiency by reducing thermionic carrier escape at high current density. The device includes a quantum well active layer and a pair of multi-layer barrier layers arranged symmetrically about the active layer. Each multi-layer barrier layer includes an inner layer abutting the active layer; and an outer layer abutting the inner layer. The inner barrier layer has a bandgap greater than that of the outer barrier layer. Both the inner and the outer barrier layer have bandgaps greater than that of the active layer. InGaN may be employed in the active layer, AlInN, AlInGaN or AlGaN may be employed in the inner barrier layer, and GaN may be employed in the outer barrier layer. Preferably, the inner layer is thin relative to the other layers. In one embodiment the inner barrier and active layers are 15 Å and 24 Å thick, respectively.06-23-2011

Guihua Liu, Radnor, PA US

Patent application numberDescriptionPublished
20090270480Markers and Methods for Assessing and Treating Psoriasis and Related Disorders - A method for prognostic or diagnostic assessment of a skin-related disorder, such as psoriasis, in a subject correlates the presence, absence, and/or magnitude of a gene in a sample with a reference standard to determine the presence and/or severity of the disorder, and/or the response to treatment for the disorder. The method enables identification of the effectiveness of candidate therapies.10-29-2009

Guopeng Liu, Plymouth Meeting, PA US

Patent application numberDescriptionPublished
20100318230Kitchens exhaust hood and make-up air handling unit optimal speed control system - Disclosed is a kitchen exhaust hood and makeup unit control system comprising a control device for controlling the variable speed drive (VSD) for the associated fan, and measurement devices comprising Volatile Organic Compound (VOC) gas transmitter devices and temperature transmitters devices. The exhaust fan VSD speed is controlled to maintain the kitchen hood area at certain comfort level (indoor air quality and thermal comfort) by monitoring the VOC concentration and exhaust duct temperature. The air quality sensors measure the concentration of multiple gases and odorous substances in the air with constant output. These substances, for example, may be cooking smoke, kitchen vapors, human odors and unpleasant smells. The exhaust fan speed is controlled using the proportional-integral-derivative (PID) control loop. The kitchen exhaust and make-up unit supply airflow rate may be measured by an airflow measurement means such as Fan Airflow Station. The kitchen make-up unit fan speed is controlled to maintain the constant airflow difference between the exhaust air and make-up air to maintain the slightly negative pressure in the kitchen area.12-16-2010

Hang Liu, Bucks, PA US

Patent application numberDescriptionPublished
20090319846ADAPTIVE ERROR CORRECTION METHOD FOR DATA TRANSMISSION AND DEVICES THEREOF - An adaptive error correction method for data transmission and the devices thereof are disclosed. By comparing the announced recovery data and data requested for error correction, no redundant join messages will be sent if the recovery data have been announced before. This will greatly reduce the number messages and save the band width of transmission.12-24-2009

Hongqi Liu, Wynnewood, PA US

Patent application numberDescriptionPublished
20100035829METHOD OF TREATING INTRAUTERINE INFLAMMATION - A method of treating intrauterine inflammation in a subject associated with intrauterine bacterial infection includes administering to the subject a therapeutically effective amount of a toll-like receptor 4 antagonist. The therapeutically effective amount administered to the subject is an amount effective in reducing intrauterine inflammation in the subject.02-11-2010

Hongzhou Liu, Pittsburgh, PA US

Patent application numberDescriptionPublished
20090144671DESIGNING INTEGRATED CIRCUITS FOR YIELD - Method and system for designing integrated circuits for yield are described. Integrated circuits are designed for yield by finding worst yield corners based on design, statistical, and environmental variables and optimizing the design in light of the worst yield corners found.06-04-2009

Patent applications by Hongzhou Liu, Pittsburgh, PA US

Hongzhou Liu, Sewickley, PA US

Patent application numberDescriptionPublished
20110153271METHODS AND SYSTEMS FOR HIGH SIGMA YIELD ESTIMATION - For an integrated circuit associated with a plurality of parameters whose values are described by a first probability distribution function, a method for estimating a failure probability includes selecting a first plurality of samples, performing a first test to determine an outcome for each of the first plurality of samples and identifying failed samples, and clustering the failed samples using a computer-implemented cluster forming method that, in some cases, returns multiple clusters. The method also includes forming a probability distribution function for each of the clusters, forming a composite probability distribution function that includes a weighted combination of the first probability distribution function and the probability distribution function for each of the clusters. The method further includes selecting a second plurality of samples using the composite probability distribution function and performing a second test to determine an outcome for each of the second plurality of samples. A failure probability can then be computed.06-23-2011
20110153272METHODS AND SYSTEMS FOR HIGH SIGMA YIELD ESTIMATION USING REDUCED DIMENSIONALITY - For an integrated circuit associated with a first plurality of parameters whose values are described by a first probability distribution function, a method for estimating a failure probability includes selecting a first plurality of samples, performing a first test to determine an outcome for each of the first plurality of samples and identifying failed samples. A second plurality of parameters is selected that has fewer parameters than the first plurality of parameters. The failed samples are clustered in the space of the second plurality of parameters using a computer-implemented cluster forming method that, in some cases, returns multiple clusters. The method also includes forming a probability distribution function for each of the clusters, forming a composite probability distribution function that includes a weighted combination of the first probability distribution function and the probability distribution function for each of the clusters. The method further includes selecting a second plurality of samples using the composite probability distribution function and performing a second test to determine an outcome for each of the second plurality of samples. A failure probability can then be computed.06-23-2011

Hsin-Yi Liu, Pittsburgh, PA US

Patent application numberDescriptionPublished
20100276975ANGLE ADJUSTABLE BACKREST MOUNTING - Angle adjustable backrest made of a lightweight, durable, adjustable, backrest for ultralight manual wheelchairs. Light-weight material can include composites for a rigid backrest for promotion of healthier and functional interface. Angle adjustment can be any desired range such as a range from −5 degree to 55 degrees (i.e. 85 degrees to 145 degree with respect to horizontal with the seat). No tools are necessary for any of the angle adjustments. The backrest has a horizontal adjustment (fore-aft) that can be any desired range such as 1 inch. The height selection depends on the length of the wheelchair frame tubes. The present invention improves the ease and simplicity of adjusting the backrest by or for the user, as well as enhances the aesthetic appearance and adds features necessary for achieving commercial readiness. The present invention can be retro fit onto a wide range for ultralight wheelchairs.11-04-2010

James Zhou Liu, Downingtown, PA US

Patent application numberDescriptionPublished
20100206244Animal Potty Chair - The present invention discloses an animal potty chair, particularly for a dog or cat, to be used indoor and/or outdoor to aid civilization of domestic animals and to improve quality of life for millions of families with animals. The animal potty chair comprising: (1) a defined space to guide an animal to release waste to a designated area; (2) a supporting mean covered with a mesh for an animal to stand and to release waste (3) a sealer-adaptor of the toilet; (4) a receptacle mean for animal waste; (5) a sensor to monitor an animal to come to a designated place; (6) a signal to indicate that an animal is/was at a designated place. The current invention has caused the revolutionary transformation of a pet from an accident-causing animal to a civilized non-human member of the family. There will be no more wet urine paw tracks left anywhere in the owner's house. Solid wastes stay on the top of the mesh, semi-liquid or loose feces fall into the toilet. The owner only needs to do minimal housekeeping, much easier than taking care of a human baby. The smell of the animal waste is reduced dramatically after the animal gets acquainted with using the current invention of an animal toilet.08-19-2010
20110146671PHARMACEUTICAL COMPOSITIONS AND METHODS OF DELIVERING THE SAME - The present invention provides a pharmaceutical composition comprising a chemical compound or a herb extract or the combination having at least one of the activities of antiviral, antibacterial, antifungal, anti-inflammatory, anti-allergy, anti-cancer, promoting membrane healing or immunomodulating, for the treatment and prevention of a disease of a mammal. The present invention also provides a system for delivering the composition to the hard-to-reach sinuses of a mammal to reduce the load of the pathogen, to reduce the amount of inflammatory mediators, to heal pathological changes, and collectively to treat a disease of a mammal, such as allergic fungal rhinosinusitis. The invented method of treating a human disease reduces infectious and inflammatory agents without causing antibiotic resistance or adverse event. The present invention additionally provides a kit for collecting the nasal wash specimen to analyze how much drug is administered into sinonasal cavities or to determine the load of microbes in rhino-sinuses.06-23-2011

Jiantao T. Liu, Murrysville, PA US

Patent application numberDescriptionPublished
20110056597METHODS OF AGING ALUMINUM ALLOYS TO ACHIEVE IMPROVED BALLISTICS PERFORMANCE - Aluminum alloy products having improved ballistics performance are disclosed. The aluminum alloy products may be underaged. In one embodiment, the underaged aluminum alloy products realize an FSP resistance that it is better than that of a peak strength aged version of the aluminum alloy product. In one embodiment, ballistics performance criteria is selected and the aluminum alloy product is underaged an amount sufficient to achieve a ballistics performance that is at least as good as the ballistics performance criteria.03-10-2011

Jianto Liu, Murrysville, PA US

Patent application numberDescriptionPublished
20100127125METAL SHEETS AND PLATES HAVING FRICTION-REDUCING TEXTURED SURFACES AND METHODS OF MANUFACTURING SAME - Metal sheets and plates having friction-reducing textured surfaces and methods of manufacturing these metal sheets and plates are disclosed herein. In an embodiment, there is provided a transportation vessel that includes at least one metal product having at least one surface that is substantially grooved, wherein the substantially grooved surface forms a riblet topography, the riblet topography including a multiplicity of adjacent permanently rolled longitudinal riblets running along at least a part of the surface, and wherein the riblet topography is coated with at least one coating sufficiently designed and applied to preserve the riblet topography. In an embodiment, the multiplicity of adjacent permanently rolled longitudinal riblets results in a friction-reducing textured surface. In an embodiment, metal product is used in fabricating at least a portion of an aircraft. In an embodiment, metal product is used in fabricating at least a portion of a rotor blade.05-27-2010

Jianxin Liu, North Huntingdon, PA US

Patent application numberDescriptionPublished
20080277837Gas Permeable Molds - Gas permeable molds and mold segments having open porosity (11-13-2008

Jinfang Liu, Lancaster, PA US

Patent application numberDescriptionPublished
20080221684Devices, systems, and methods to fixate tissue within the regions of body, such as the pharyngeal conduit - Devices, systems and methods develop static and/or kinetic and/or pressure forces to fixate or brace tissue in targeted pharyngeal structures and individual anatomic components within the pharyngeal conduit.09-11-2008
20110057756Rare Earth Composite Magnets with Increased Resistivity - Dielectric rare earth fluorides are blended with rare earth magnet powders to produce high-resistivity fluoride composite rare earth magnets.03-10-2011
20110200839Rare Earth Laminated, Composite Magnets With Increased Electrical Resistivity - Laminated, composite, permanent magnets comprising layers of permanent magnets separated by layers of dielectric or high electrical resistivity substances, wherein the laminated magnets indicate increased electrical resistivity.08-18-2011

Patent applications by Jinfang Liu, Lancaster, PA US

John Liu, Murrysville, PA US

Patent application numberDescriptionPublished
20090011272METAL BODIES CONTAINING MICROCAVITIES AND APPARATUS AND METHODS RELATING THERETO - Monolithic metal bodies (e.g., hard aluminum alloys) comprising a continuous microcavity contained within the body are disclosed. The ratio of the cross-sectional area of the metal body to the cross-sectional area of the microcavity may be not greater than 10. The produced metal bodies may be used in structural applications (e.g., aerospace vehicles) to monitor or test the integrity of the metal body.01-08-2009
20100127125METAL SHEETS AND PLATES HAVING FRICTION-REDUCING TEXTURED SURFACES AND METHODS OF MANUFACTURING SAME - Metal sheets and plates having friction-reducing textured surfaces and methods of manufacturing these metal sheets and plates are disclosed herein. In an embodiment, there is provided a transportation vessel that includes at least one metal product having at least one surface that is substantially grooved, wherein the substantially grooved surface forms a riblet topography, the riblet topography including a multiplicity of adjacent permanently rolled longitudinal riblets running along at least a part of the surface, and wherein the riblet topography is coated with at least one coating sufficiently designed and applied to preserve the riblet topography. In an embodiment, the multiplicity of adjacent permanently rolled longitudinal riblets results in a friction-reducing textured surface. In an embodiment, metal product is used in fabricating at least a portion of an aircraft. In an embodiment, metal product is used in fabricating at least a portion of a rotor blade.05-27-2010

Li H. Liu, South Williamsport, PA US

Patent application numberDescriptionPublished
20080276411Wall hanging vacuum cleaner - A new vacuum cleaner/bracket combination has a bracket that mates with an indented side on a vacuum cleaner or blower. The indented side has a downwardly-facing upper lip portion and a laterally-facing side lip portion. There is an upper groove portion behind the downwardly-facing upper lip portion, and a side groove portion behind the side lip portion. The bracket has an upper rim portion that is configured to fit within the upper groove portion on the indented side. A side rim portion on the bracket is positioned below the upper rim portion. It is configured to fit within the side groove portion on the indented side when the upper rim portion on the bracket fits within the upper groove portion.11-13-2008
20110107547Combination vacuum cleaner, dolly, and mounting bracket - The disclosed bracket can be used to hang vacuum cleaners that have a detachable dolly. A plate on the bracket mounts to a wall. A stem portion fits within a slot on the dolly. Lower wall segments on the stem portion extend from the wall plate and have vertical outer edges. Intermediate wall segments extend between the lower wall segments and upper wall segments that have lower horizontal limits that are closer together than the lower wall segments are, are positioned laterally outwards from the stem portion, and taper toward each other above their lower limits. Side rim portions extend from the upper wall segments and fit within grooves on the vacuum cleaner. The outer edges of the lower wall segments are farther apart than the inner edges of the side rim portions are, and closer together than the outer edges of the side rim portions are.05-12-2011

Patent applications by Li H. Liu, South Williamsport, PA US

Liming Liu, Upper Dublin, PA US

Patent application numberDescriptionPublished
20090324614FC RECEPTOR BINDING PROTEINS - This disclosure provides, inter alia, proteins that bind to FcRn, e.g., immunoglobulins that inhibit FcRn with high affinity and selectivity. The FcRn-binding proteins can be used to treat a variety of disorders including autoimmune disorders.12-31-2009

Nannan Liu, Collegeville, PA US

Patent application numberDescriptionPublished
20080214640Thrombopoietin mimetics - Invented are non-peptide TPO mimetics. Also invented are novel processes and intermediates used in the preparation of the presently invented compounds. Also invented is a method of treating thrombocytopenia, in a mammal, including a human, in need thereof which comprises administering to such mammal an effective amount of a selected hydroxy-1-azobenzene derivative.09-04-2008
20090155203THROMBOPOIETIN MIMETICS - Invented are non-peptide TPO mimetics. Also invented are novel processes and intermediates used in the preparation of the presently invented compounds. Also invented is a method of treating thrombocytopenia, in a mammal, including a human, in need thereof which comprises administering to such mammal an effective amount of a selected hydroxy-1-azobenzene derivative.06-18-2009
20090176746THROMBOPOIETIN MIMETICS - Invented are non-peptide TPO mimetics. Also invented are novel processes and intermediates used in the preparation of the presently invented compounds. Also invented is a method of treating thrombocytopenia, in a mammal, including a human, in need thereof which comprises administering to such mammal an effective amount of a selected hydroxy-1-azobenzene derivative.07-09-2009
20090176973THROMBOPOIETIN MIMETICS - Invented are non-peptide TPO mimetics. Also invented are novel processes and intermediates used in the preparation of the presently invented compounds. Also invented is a method of treating thrombocytopenia, in a mammal, including a human, in need thereof which comprises administering to such mammal an effective amount of a selected hydroxy-1-azobenzene derivative.07-09-2009

Patent applications by Nannan Liu, Collegeville, PA US

Qindu Liu, Upper Darby, PA US

Qingdu Liu, Bala Cynwyd, PA US

Patent application numberDescriptionPublished
20090286737ERBB INTERFACE PEPTIDOMIMETICS AND METHODS OF USE THEREOF - Peptides, mimetics and antibodies of erbB, TNF, and IgSF receptors and pharmaceutical compositions comprising the same are described. Methods of using such antibodies, peptides, and mimetics in therapeutic, prophylactic, imaging and diagnostic applications are disclosed.11-19-2009
20100076174ErbB Interface Peptidomimetics And Methods Of Use Thereof - Peptides, mimetics and antibodies of erbB, TNF, and IgSF receptors and pharmaceutical compositions comprising the same are described. Methods of using such antibodies, peptides, and mimetics in therapeutic, prophylactic, imaging and diagnostic applications are disclosed.03-25-2010
20100120688ErbB Interface Peptidomimetics And Methods Of Use Thereof - Peptides, mimetics and antibodies of erbB, TNF, and IgSF receptors and pharmaceutical compositions comprising the same are described. Methods of using such antibodies, peptides, and mimetics in therapeutic, prophylactic, imaging and diagnostic applications are disclosed.05-13-2010
20100239587ErbB Interface Peptidomimetics And Methods Of Use Thereof - Peptides, mimetics and antibodies of erbB, TNF, and IgSF receptors and pharmaceutical compositions comprising the same are described. Methods of using such antibodies, peptides, and mimetics in therapeutic, prophylactic, imaging and diagnostic applications are disclosed.09-23-2010

Qingjie Liu, Newtown, PA US

Patent application numberDescriptionPublished
20100160303CARBAZOLE CARBOXAMIDE COMPOUNDS USEFUL AS KINASE INHIBITORS - Compounds having the formula (I), and enantiomers, and diastereomers, pharmaceutically-acceptable salts, thereof,06-24-2010

Ronggang Liu, King Of Prussia, PA US

Patent application numberDescriptionPublished
20100113444PROLYL HYDROXYLASE INHIBITORS - The invention described herein relates to certain pyrimidinetrione N-substituted glycine derivatives of formula (I), (I) which are antagonists of HIF prolyl hydroxylases and are useful for treating diseases benefiting from the inhibition of this enzyme, anemia being one example.05-06-2010
20110034499SPIROINDOLINES AS MODULATORS OF CHEMOKINE RECEPTORS - The present invention relates to a compound of the following formula:02-10-2011
20110124671SPIROINDENES AND SPIROINDANES AS MODULATORS OF CHEMOKINE RECEPTORS - The present invention relates to a compound of the following formula:05-26-2011

Ruiyan Liu, Yardley, PA US

Patent application numberDescriptionPublished
20090093472ORTHO PYRROLIDINE, BENZYL-SUBSTITUTED HETEROCYCLE CCR1 ANTAGONISTS FOR AUTOIMMUNE DISEASES & INFLAMMATION - Compounds of the formula04-09-2009
20100173823ALPHA2C ADRENORECEPTOR AGONISTS - In its many embodiments, the present invention relates to a novel class of phenylmorpholine and phenylthiomorpholine compounds useful as α2C adrenergic receptor agonists, pharmaceutical compositions containing the compounds, and methods of treatment, prevention, inhibition, or amelioration of one or more diseases associated with the α2C adrenergic receptor agonists using such compounds or pharmaceutical compositions.07-08-2010

Patent applications by Ruiyan Liu, Yardley, PA US

Shaiw Wen Liu, Honeybrook, PA US

Patent application numberDescriptionPublished
20110200625PHARMACEUTICAL COMPOSITION - A nonirritant, thickened pharmaceutical composition comprising a drug which is normally solid and which has anti-angiogenesis properties and/or immunosuppressant properties, a normally solid dermal penetration-facilitator for the drug, a solvent which is capable of dissolving the drug and the facilitator; and a thickening agent.08-18-2011

Tie Liu, Emmaus, PA US

Patent application numberDescriptionPublished
20090275322PREVENTION OF AUDIO POP IN A DIGITAL AUDIO DEVICE - An electronic audio device with a digital audio output channel in which an amplifier output voltage is gradually ramped up and down to avoid causing a popping sound when the device is turned on and off. This is accomplished without employing any additional hardware, by incrementally changing a digital input word applied to a digital audio source, such as a DSP, so as to gradually change the amplifier output voltage between a minimum, such as zero volts, and a DC working voltage. On powering up, the amplifier is only turned on after the digital word is applied, but while it still results in a minimum amplifier output, and on powering down the amplifier is turned off after it's output has been ramped down, but before removing the digital input word. Sources and output channels can also be switched over by powering down, and then powering up, following the same method.11-05-2009

Wansheng Liu, State College, PA US

Patent application numberDescriptionPublished
20100009374SIRE EARLY SELECTION FOR MALE FERTILITY USING SINGLE NUCLEOTIDE POLYMORPHISMS (SNPS) OF THE DAZL GENE - Methods and materials for identifying bovine males which will produce semen which will exhibit a higher rate of successfully impregnation by either artificial insemination or natural mating. The method employs SNPs that have been identified in the bDAZL gene which are associated with enhanced (or decreased) male fertility in bovine males and haplotypes formed from such SNPs. The method herein can be used to identify male dairy or beef cattle. The method herein can be applied to bovine animals at an appropriate time and particularly at birth or in utero. The invention further provides kits for conduction assays to assess bovine male fertility/infertility. The invention additionally provides a method of breeding cattle employing the methods and materials herein.01-14-2010

Wenjun Liu, King Of Prussia, PA US

Patent application numberDescriptionPublished
20080264855METHOD AND APPARATUS FOR TREATING WASTEWATER - This invention is directed to a wastewater treatment system having a fluidizable media carrying anoxic bacteria in a first treatment zone and a filter membrane positioned in a second treatment zone. A wastewater is contacted with the fluidizable media and further contacted with air and a filter membrane.10-30-2008
20080314829Dynamic Control of Membrane Bioreactor System - A method of controlling the operating parameters of a membrane bioreactor system, the method including the steps of determining a control algorithm based on the relationship between the value of a parameter of the influent provided to the membrane bioreactor system and an optimal performance measurement parameter of the system and controlling one or more operating parameters of the membrane bioreactor system using the determined control algorithm.12-25-2008
20090026120METHOD AND APPARATUS FOR TREATING WASTEWATER - This invention is directed to a wastewater treatment system having a fluidizable media carrying anoxic bacteria in a first treatment zone and a filter membrane positioned in a second treatment zone. A wastewater is contacted with the fluidizable media and further contacted with air and a filter membrane.01-29-2009
20090090670WASTEWATER TREATMENT SYSTEM AND METHOD - The invention is directed to a wastewater treatment system having an anoxic biological treatment zone, an aerobic biological treatment zone and a separator. The concentration of oxygen in streams within the system is strategically managed for improved removal of nutrient from the wastewater. A source of biodegradable carbon may be introduced to reduce the concentration of oxygen within the system. An effective treatment time under anoxic or aerobic conditions may further be varied.04-09-2009
20100170847MEMBRANE CLEANING USING AN AIRLIFT PUMP - A membrane module (07-08-2010

Patent applications by Wenjun Liu, King Of Prussia, PA US

Wenjun Liu, Wayne, PA US

Patent application numberDescriptionPublished
20100300968MEMBRANE CLEANING WITH PULSED GAS SLUGS - Aspects and embodiments of the present application are direction to systems and methods for treating fluids and to systems and methods for cleaning membrane modules used in the treatment of fluids. Disclosed herein is a membrane filtration system and a method of operating same. The membrane filtration system comprises a plurality of membrane modules positioned in a feed tank, at least one of the membrane modules having a gas slug generator positioned below a lower header thereof, the gas slug generator configured and arranged to deliver a gas slug along surfaces of membranes within the at least one of the membrane modules and a global aeration system configured to operate independently from an aeration system providing a gas to the gas slug generator, the global aeration system configured and arranged to induce a global circulatory flow of fluid throughout the feed tank.12-02-2010
20110089105HYBRID AEROBIC AND ANAEROBIC WASTEWATER AND SLUDGE TREATMENT SYSTEMS AND METHODS - A hybrid method and system of treating wastewater with reduced energy usage is disclosed. The treatment system has a sorption system, an anaerobic digester that digests or converts at least a portion of the solids or sludge from the sorption system, and an aerobic treatment tank that partially reduces oxygen demand of a portion of the sludge from the sorption tank.04-21-2011

Xiang-Qian Liu, Norristown, PA US

Patent application numberDescriptionPublished
20080227032ENVIRONMENTAL FRIENDLY PHOTOACID GENERATORS (PAGs) WITH NO PERFLUOROOCTYL SULFONATES - Novel classes of ionic photoacid generator (PAGs) compounds having relatively environmentally friendly anions with no perfluorooctyl sulfonate (no-PFOS) are provided and photoresist composition that comprise such compounds. The new PAGs produce a photoacid having a short or no perfluoro alkyl chain (i.e., no-PFOS) attached to a variety of functional groups. The PAGs of the invention are useful as photoactive component in the chemically amplified resist compositions used for microfabrication.09-18-2008

Patent applications by Xiang-Qian Liu, Norristown, PA US

Xiaoli Liu, State College, PA US

Patent application numberDescriptionPublished
20090125238Method for Mechanical and Capillary Seal Analysis of a Hydrocarbon Trap - Method for making a probabilistic determination of total seal capacity for a hydrocarbon trap, simultaneously considering both capillary entry pressure and mechanical seal capacity, and where capillary entry pressure is estimated by relating it directly to the buoyancy pressure applied by the hydrocarbon column to the top seal. The method thus considers the substantial uncertainty associated with input parameters, which uncertainty limits the utility of such analyses for robust hydrocarbon column height and fluid contact predictions. The method disclosed for estimating seal capillary entry pressure, the requisite input parameter for capillary seal capacity analysis, by inverting trap parameters avoids the need for direct measurement by mercury injection capillary capacity tests on small pieces of rock, which test results often are not available for all desired locations nor are they necessarily representative of adjacent rocks in the seal.05-14-2009

Xiaoming Liu, Orefield, PA US

Patent application numberDescriptionPublished
20090041971POLARIZER FILMS AND METHODS OF MAKING THE SAME - In general, in one aspect, the invention features an article that includes a layer including a plurality of spaced-apart portions of a first material extending along a first direction. The layer transmits about 20% or more of light of wavelength λ having a first polarization state incident on the layer along a path. The layer transmits about 2% or less of light of wavelength λ having a second polarization state incident on the layer along the path, the first and second polarization states being orthogonal. For wavelength λ, the first material has a refractive index of 1.8 or more and an extinction coefficient of 1.8 or more, and λ is 300 nm or less.02-12-2009
20090053655Methods for forming patterned structures - In general, in a first aspect, the invention features a method that includes forming a first layer comprising a first material over a surface of a second layer, wherein forming the first layer includes sequentially forming a plurality of monolayers of the second material over the surface of the second layer, the second layer comprises a plurality of rows of a second material extending along a first direction and spaced from one another in a second direction orthogonal to the first direction, and the first layer conforms to the surface of the second layer. The method further includes removing portions of the first layer to produce a plurality of rows of the first material extending along the first direction and spaced from one another in the second direction and removing portions of a third layer comprising a third material, where the portions correspond to intervals between the second plurality of rows so that removing the portions forms a plurality of rows of the third material extending along the first direction and spaced apart from one another. The first and second materials are different.02-26-2009

Xiaoyu Liu, Pittsburgh, PA US

Patent application numberDescriptionPublished
20110101788Wireless Energy Transfer System - A wireless energy transfer system includes a first energy transfer unit having at least one resonant frequency, a second energy transfer unit having the at least one resonant frequency, and a load. The first wireless energy transfer unit includes a first coil magnetically coupled to a first wireless energy transfer cell, and the second wireless energy transfer unit includes a second coil magnetically coupled to a second wireless energy transfer cell. The first coil receives first energy and through the magnetic coupling between the first coil and the first wireless energy transfer cell, the first wireless energy transfer cell is caused to generate second energy, wherein the second wireless energy transfer cell receives the second energy and through the magnetic coupling between the second wireless energy transfer cell and the second coil, the second coil is caused to provide third electromagnetic wave energy to the load.05-05-2011

Xinping Liu, Doylestown, PA US

Patent application numberDescriptionPublished
20110075156RANGE FINDER - A system and method for measuring a height of objects on a moving surface comprising providing a linear image sensor positioned transverse to a direction of travel of the moving surface, and at least one light source positioned collinear to the linear image sensor and proximate to an edge of the moving surface so that the light source projects a unique patterned light sequence across a width of the moving surface, detecting a transverse shift in a portion of the unique patterned light sequence with respect to the direction of travel of the moving surface as an object passes through the unique patterned light sequence, determining an amount of shift of the portion of the unique patterned light sequence, and determining a height of the object based on the portion of the unique patterned light sequence shift.03-31-2011

Xinyin Liu, Exton, PA US

Patent application numberDescriptionPublished
20100041770POLYMER-CERAMIC COMPOSITE AND METHOD - Methods and devices are shown for a composite material that is easily applied to a surface such as a bone defect in need of filling or reinforcement, etc. The composite material provides good mechanical properties such as compressive strength upon curing in the presence of water. Selected materials and methods as described are further bioabsorbable with absorption rates that are controllable to provide desired morphology over time. In selected embodiments a pharmaceutical agent further provides benefits such as bone growth, infection resistance, pain management, etc.02-18-2010

Yixiong Liu, Greensburg, PA US

Patent application numberDescriptionPublished
20090004440CUTTING INSERT WITH A WEAR-RESISTANT COATING SCHEME EXHIBITING WEAR INDICATION AND METHOD OF MAKING THE SAME - A coated cutting insert for use in a chip-forming material removal operation wherein the coated cutting insert includes a substrate that has a flank surface and a rake surface and the flank surface intersects the rake surface to form a cutting edge at the intersection. There is a wear-resistant coating scheme that adheres to at least a portion of the substrate. The wear-resistant coating scheme includes one or more coating layers of one or more of alumina, hafnia and zirconia. There is a wear indicating coating that adheres to at least a portion of the wear-resistant coating scheme. The wear indicating coating includes M(O01-01-2009
20090004449Cutting insert with a wear-resistant coating scheme exhibiting wear indication and method of making the same - A coated cutting insert for use in a chip-forming material removal operation wherein the coated cutting insert includes a substrate that has a flank surface and a rake surface and the flank surface intersects the rake surface to form a cutting edge at the intersection. There is a wear-resistant coating scheme that adheres to at least a portion of the substrate. The wear-resistant coating scheme includes one or more coating layers of one or more of alumina, hafnia and zirconia. There is a wear indicating coating that adheres to at least a portion of the wear-resistant coating scheme. The wear indicating coating includes M(O01-01-2009
20090155559Coated article with nanolayered coating scheme - A coated article that includes a substrate and a wear-resistant coating scheme. The coated article may be a cutting insert shown to improve performance in chip-forming material removal operations or a wear-resistant component used in chipless forming operations. The wear-resistant coating scheme has an underlayer and top layer containing aluminum, chromium, and nitrogen. The coating scheme also includes a mediate multi-periodicity nanolayer coating scheme containing titanium, aluminum, chromium and nitrogen. The mediate multi-periodicity nanolayer coating scheme includes a plurality of sets of alternating layer arrangements. Each one of the alternating layer arrangements has a base layer comprising titanium, aluminum and nitrogen and a nanolayer region having a plurality of sets of alternating nanolayers. Each set of alternating nanolayers has one nanolayer having aluminum, chromium, titanium and nitrogen and another nanolayer having aluminum, chromium, titanium and nitrogen. The base layer has a base layer thickness and the nanolayer region has a nanolayer region thickness. The base layer thickness is smaller than the nanolayer region thickness.06-18-2009
20110081539Aluminum Titanium Nitride Coating and Method of Making Same - Hard coatings and methods of making the hard coatings comprising aluminum titanium nitride which are usable on cutting tools are disclosed. The coatings include at least one aluminum titanium nitride layer having between about 0 and about 15 weight percent hexagonal phase and a composition of (Al04-07-2011
20110107679COATED CUTTING INSERT AND METHOD FOR MAKING THE SAME - A coated cutting insert for removing material from a workpiece that includes a substrate is disclosed. A wear-resistant coating on the substrate that includes an α-alumina layer and a Zr— or Hf— carbonitride outer layer deposited on the α-alumina layer. The Zr— or Hf— carbonitride outer layer is subjected to a post-coat wet blasting treatment. The wet blasting changes the stress condition of the exposed alumina coating layer from an initial tensile stress condition to a compressive stress condition.05-12-2011

Yixiong Liu, Latrobe, PA US

Patent application numberDescriptionPublished
20100255345COATED PCBN CUTTING INSERT, COATED PCBN CUTTING TOOL USING SUCH COATED PCBN CUTTING INSERT, AND METHOD FOR MAKING THE SAME - A coated polycrystalline cubic boron nitride cutting insert useful in a cutting tool for removing material from a workpiece, and a method for making the same. The cutting insert including a polycrystalline cubic boron nitride substrate with a rake surface and at least one flank surface, and a cutting edge formed at the juncture between the rake surface and the flank surface. A wear-resistant coating scheme is on the polycrystalline cubic boron nitride substrate. The wear-resistant coating scheme includes the following coating layers. An inner coating layer region is on at least some of the rake surface and at least some of the flank surface of the polycrystalline cubic boron nitride substrate. An alumina-containing coating layer region, which has at least one exposed alumina coating layer, is on the inner coating layer region. The exposed alumina coating layer exhibiting a post-blasted stress condition with stress ranging between about 50 MPa (tensile stress) and about −2 GPa (compressive stress) as measured by XRD using the Psi tilt method and the (024) reflection of alumina. The exposed coating layer is the result of wet blasting an outer titanium-containing coating layer from the surface of the alumina-containing coating layer region.10-07-2010
20110064530COATED CERAMIC CUTTING INSERT AND METHOD FOR MAKING THE SAME - A coated ceramic cutting insert for removing material from a workpiece, as well as a method for making the same, that includes a ceramic substrate with a rake surface and at least one flank surface wherein a cutting edge is at the juncture therebetween. A wear-resistant coating scheme that includes an alumina-containing base coating layer region, which has at least one exposed alumina coating layer, deposited by chemical vapor deposition on the substantially all of the surfaces of the ceramic substrate that experience wear during removal of material from the workpiece. The exposed alumina coating layer exhibits a blasted stress condition ranging between about 50 MPa (tensile stress) and about −2 GPa (compressive) as measured by XRD using the Psi tilt method and the (024) reflection of alumina. The exposed alumina coating layer is the result of wet blasting a titanium-containing outer coating layer region from the surface of the alumina-containing base coating layer region.03-17-2011

Yuan Liu, Lansdale, PA US

Patent application numberDescriptionPublished
20090117590Human calcium sensitive potassium channel beta3 subunit proteins, encoding nucleic acid and uses thereof - The present invention is directed to novel human DNA sequences encoding calcium sensitive potassium channel subunits β2, β3a, β3b, β3c, and β3d, the proteins encoded by the DNA sequences, vectors comprising the DNA sequences, host cells containing the vectors, and methods of identifying inhibitors and agonists of calcium sensitive potassium channels containing human β2, β3a, β3b, β3c, or β3d subunits and inhibitors and agonists of β3 gene transcription.05-07-2009

Zhan-Bin Liu, West Chester, PA US

Patent application numberDescriptionPublished
20080220143Production of Very Long Chain Polyunsaturated Fatty Acids in Oil Seed Plants - Oilseed plants which have been transformed to produce at least 8.0% arachidonic acid (ARA) as well as uses of oils and seeds obtained from such transformed plants in a variety of food and feed applications are described.09-11-2008

Patent applications by Zhan-Bin Liu, West Chester, PA US

Zhendong Liu, King Of Prussia, PA US

Patent application numberDescriptionPublished
20100112906Chemical mechanical polishing composition and methods relating thereto - A method for chemical mechanical polishing of a substrate comprising a germanium-antimony-tellurium chalcogenide phase change alloy using a chemical mechanical polishing composition comprising water; 1 to 40 wt % colloidal silica abrasive particles having an average particle size of ≦50 nm; and 0 to 5 wt % quarternary ammonium compound; wherein the chemical mechanical polishing composition is oxidizer free and chelating agent free; and, wherein the chemical mechanical polishing composition has a pH >6 to 12.05-06-2010
20100151683Chemical mechanical polishing composition and methods relating thereto - A method for chemical mechanical polishing of a substrate comprising a barrier material in the presence of at least one of an interconnect metal and a low-k dielectric material using a chemical mechanical polishing composition comprising water; 1 to 40 wt % abrasive having an average particle size of ≦100 nm; 0.001 to 5 wt % quaternary compound; a material having a formula (I):06-17-2010
20110111595Chemical mechanical polishing composition and methods relating thereto - A chemical mechanical polishing composition useful for chemical mechanical polishing of a substrate, wherein the substrate comprises a silicon oxide material and a silicon nitride material; and methods of making and using the chemical mechanical polishing composition. The chemical mechanical polishing composition comprises, as initial components: at least one of a first substance and a second substance; wherein the first substance is according to formula I05-12-2011

Zhendong Liu, Prussia, PA US

Patent application numberDescriptionPublished
20100279507 Method for chemical mechanical polishing a substrate - A method for chemical mechanical polishing of a substrate, comprising: providing a substrate, wherein the substrate comprises silicon dioxide; providing a chemical mechanical polishing composition, wherein the chemical mechanical polishing composition comprises: water, an abrasive; a diquaternary cation according to formula (I); and optionally a quaternary alkylammonium compound; providing a chemical mechanical polishing pad; creating dynamic contact at an interface between the chemical mechanical polishing pad and the substrate; and dispensing the chemical mechanical polishing composition onto the chemical mechanical polishing pad at or near the interface between the chemical mechanical polishing pad and the substrate; wherein the chemical mechanical polishing composition has a pH of 2 to 6; wherein the chemical mechanical polishing composition exhibits a silicon dioxide removal rate of at least 1,500 Å/min.11-04-2010

Zhijing Liu, Audubon, PA US

Patent application numberDescriptionPublished
20080306897System for Providing Healthcare Operation Specific User Interface Display Images - A system provides a user interface for viewing nursing problems with multiple levels of granularity in a knowledge base and rendered in an application that are dependent on context of problems, patient demographic information and information needed by a user interface image. A user interface system presents patient medical problem information to a user. The system includes a first search processor for automatically searching a knowledge base of information associating multiple different medical problems with corresponding attributes to find an attribute indicating a particular characteristic of a particular medical problem, in response to occurrence of an event. A display processor initiates generation of data representing a display image. The display image includes, a first image area for including data indicating candidate medical problems and associated attributes and a second image area for including data representing assigned medical problems of a particular patient and enabling a user to select a medical problem for transfer from the first image area to the second image area.12-11-2008

Patent applications by Zhijing Liu, Audubon, PA US

Zhi (lewis) Liu, Paoli, PA US

Patent application numberDescriptionPublished
20100293806SYSTEMS AND METHODS FOR DRYING A ROTATING SUBSTRATE - A system of drying a surface of a substrate is provided. The system includes a rotary support for supporting a substrate; and an assembly comprising a first dispenser, a second dispenser, and a third dispenser, the assembly positioned above the surface of the substrate, the second and third dispensers positioned on the assembly adjacent to and in contact with one another and spaced from the first dispenser, the second dispenser having an opening that is larger than an opening of the third dispenser, and the second dispenser being located between the first and third dispensers; and means for translating the assembly generally parallel to the surface of the substrate.11-25-2010

Patent applications by Zhi (lewis) Liu, Paoli, PA US

Zhiwen Liu, State College, PA US

Patent application numberDescriptionPublished
20100309465COHERENT ANTI-STOKES RAMAN HOLOGRAPHY - Apparatus and methods of four wave mixing (FWM) holography are described, including illuminating a sample with a first beam, a second beam, and a third beam, and combining the generated FWM signal with a reference beam at a imaging device to obtain holographic image data. In some examples, the first and second beams may be provided by a single pump-probe beam. The third beam may be a Stokes beam or an anti-Stokes beam. A representative example is coherent anti-Stokes Raman holography (CARS holography), which includes illuminating a sample with a pump/probe beam and a Stokes beam to obtain a CARS signal from the sample; and combining the CARS signal with a reference beam to obtain a CARS hologram.12-09-2010

Zhong-Min Liu, Doylestown, PA US

Patent application numberDescriptionPublished
20080232008Electrostatic discharge safe under conveyor antenna - An antenna for use in a conveyor system in which items on which radio frequency identification tags are disposed are moved on a conveyor along a path of travel, includes a ground plane, a substrate having a bottom surface received adjacent the ground plane, at least one patch element disposed on a top surface of the substrate, a cover received adjacent the top surface of the substrate, and a front static conductive strip disposed along a front edge of the cover. The antenna is disposed beneath the conveyor and a front edge of the antenna is transverse to the path of travel. The front static conductive strip is electrically connected to the ground plane such that an electrostatic discharge event adjacent the front static conductive strip is discharged to the ground plane.09-25-2008
20100277319RADIO FREQUENCY IDENTIFICATION TAG IDENTIFICATION SYSTEM - A conveyor system for processing items on which radio frequency identification tags are disposed has a conveyor that conveys items through a path of travel, and an antenna disposed proximate the path of travel. Circuitry in communication with the antenna may associate RFID tag data with a package on the conveyor based on a difference signal from elements in the antenna.11-04-2010

Patent applications by Zhong-Min Liu, Doylestown, PA US

Zhu Liu, Pittsburgh, PA US

Patent application numberDescriptionPublished
20110045557Novel Fusion Carbonic Anhydrase/Cellulose Binding Polypeptide Encoded by a Novel Hybrid Gene, and Method of Creating and Using the Same - The invention relates a novel hybrid carbonic anhydrase catalyst with the potential to contribute significantly to meeting targeted reductions in greenhouse gas emissions. In a preferred embodiment of the present invention at least a portion of a cellulose binding domain (CBD) of a protein is fused to another protein, carbonic anhydrase, (CA) to create a new multi-functional protein which can bind tightly to cellulose while maintaining its native catalytic ability to process CO02-24-2011