Patent application number | Description | Published |
20120117051 | MULTI-MODAL APPROACH TO SEARCH QUERY INPUT - Search queries containing multiple modes of query input are used to identify responsive results. The search queries can be composed of combinations of keyword or text input, image input, video input, audio input, or other modes of input. The multiple modes of query input can be present in an initial search request, or an initial request containing a single type of query input can be supplemented with a second type of input. In addition to providing responsive results, in some embodiments additional query refinements or suggestions can be made based on the content of the query or the initially responsive results. | 05-10-2012 |
20120296776 | ADAPTIVE INTERACTIVE SEARCH - A method, system, and computer-readable medium for searching for items in a set of items using a similarity model. These search techniques may be used in an online purchasing system. Receiving orders for items may comprise receiving input from a user indicating a request for a first item in the set of items, picking a first plurality of items from the set of items based on the first item and a similarity model, presenting the first plurality of items to the user, and receiving a request from the user for a second item in the first plurality of items. The similarity model may represent similarity between items in the set of items and may be used to select a subset of items to quickly to lead to identification of an item of interest. | 11-22-2012 |
20120296900 | ADAPTIVELY LEARNING A SIMILARITY MODEL - A method, system, and computer-readable storage medium for computing a representation of similarity among items in a set of items. Computing a representation of similarity items may comprise generating a first similarity model that represents characteristics of the set of items, the characteristics being indicative of similarity among the items in the set of items. Additionally, computing the representation of similarity may comprise adaptively selecting a subset of the set of items for similarity evaluation based on the first similarity model, receiving a similarity evaluation for the adaptively-selected subset of items, and generating a second similarity model based on the first to similarity model and the received similarity evaluation. | 11-22-2012 |
20120300122 | ADAPTIVE SUPER RESOLUTION FOR VIDEO ENHANCEMENT - A method of operating a computer system to reconstruct a high-resolution frame from a set of low-resolution frames of a video sequence is described. The high-resolution frame may be displayed on a high-resolution display device such as a high-definition television (HDTV). Initial estimates and priors for each of a plurality of quantities including blur kernel, motion between frames, noise level, and the estimate of the high-resolution frame are determined. The initial estimates are refined using an iterative process that iterates between estimating each of the plurality of quantities based on the current estimates for the plurality of quantities. When it is determined that a quality metric is above a threshold, further iteration is halted and the high-resolution frame is output for storage and/or display. The process may be repeated for outputting a high-resolution video sequence based on an input low-resolution video sequence. | 11-29-2012 |
20130202205 | SYSTEM AND METHOD FOR SEMANTICALLY ANNOTATING IMAGES - Techniques for semantically annotating images in a plurality of images, each image in the plurality of images comprising at least one image region. The techniques include identifying at least two similar images including a first image and a second image, identifying corresponding image regions in the first image and the second image, and assigning, using at least one processor, annotations to image regions in one or more images in the plurality of images by using a metric of fit indicative of a degree of match between the assigned annotations and the corresponding image regions. The metric of fit may depend on at least one annotation for each image in a subset of the plurality of images and the identified correspondence between image regions in the first image and the second image. | 08-08-2013 |
20140169700 | BAYESIAN APPROACH TO ALIGNMENT-BASED IMAGE HALLUCINATION - Various technologies described herein pertain to enhancing a quality attribute of an input image. The input image can have a first level of the quality attribute. Dense correspondences between the input image and candidate exemplar images, which are included in an image database, can be computed utilizing a dense image alignment technique. The candidate exemplar images can have a second level of the quality attribute. Further, the candidate exemplar images can be warped to align with the input image based upon the dense correspondences. Moreover, patches from the candidate exemplar images as warped can be integrated with the input image to generate an output image. The output image can have the second level of the quality attribute. | 06-19-2014 |
20140354693 | LAYERED IMAGE UNDERSTANDING - The subject disclosure is directed towards layered image understanding by which a layered scene representation is generated for an image. Providing such a scene representation explains a scene being presenting in the image by defining that scene's semantic structure. To generate the layered scene representation, the subject disclosure recognizes objects within the image by combining objects sampled from annotated image data and determining whether that combination is both semantically well-formed and matches the visual appearance of the image. The objects are transformed and then can be used to modify the query image. The subject disclosure models the objects into semantic segments that form a portion of the scene representation. | 12-04-2014 |
20140376819 | IMAGE RECOGNITION BY IMAGE SEARCH - One or more aspects of the subject disclosure are directed towards identifying objects within an image via image searching/matching. In one aspect, an image is processed into bounding boxes, with the bounding boxes further processed to each surround a possible object. A sub-image of pixels corresponding to the bounding box is featurized for matching with tagged database images. The information (tags) associated with any matched images is processed to identify/categorize the sub-image and thus the object corresponding thereto. | 12-25-2014 |
Patent application number | Description | Published |
20110243450 | MATERIAL RECOGNITION FROM AN IMAGE - A method of operating a computer system to perform material recognition based on multiple features extracted from an image is described. A combination of low-level features extracted directly from the image and multiple novel mid-level features extracted from transformed versions of the image are selected and used to assign a material category to a single image. The novel mid-level features include non-reflectance based features such as the micro-texture features micro jet and micro-SIFT and the shape feature curvature, and reflectance-based features including edge slice and edge ribbon. An augmented Latent Dirichlet Allocation (LDA) model is provided as an exemplary Bayesian framework for selecting a subset of features useful for material recognition of objects in an image. | 10-06-2011 |
20120105728 | METHODS AND APPARATUS FOR REDUCING STRUCTURED NOISE IN VIDEO - A method of operating a computer system to reduce structured noise in a video is described. Patches in a frame of a sequence of video frames are selected using a modified non-local means (NLM) search algorithm with a reduced search complexity compared to conventional NLM search algorithms. The set of spatial neighboring patches in a frame is extended to include patches in adjacent frames of the video sequence. Patches in the adjacent frames are selected based, at least in part, on a projection of a location of a pixel in the frame into the adjacent frames using a motion estimation algorithm. An average value determined from the combined set of patches is used to replace the pixel currently being processed. | 05-03-2012 |
20130147911 | AUTOMATIC 2D-TO-STEREOSCOPIC VIDEO CONVERSION - In general, a “Stereoscopic Video Converter” (SVC) provides various techniques for automatically converting arbitrary 2D video sequences into perceptually plausible stereoscopic or “3D” versions while optionally generating dense depth maps for every frame of the video sequence. In particular, the automated 2D-to-3D conversion process first automatically estimates scene depth for each frame of an input video sequence via a label transfer process that matches features extracted from those frames with features from a database of images and videos having known ground truth depths. The estimated depth distributions for all image frames of the input video sequence are then used by the SVC for automatically generating a “right view” of a corresponding stereoscopic image for each frame (assuming that each original input frame represents the “left view” of the stereoscopic image). | 06-13-2013 |
20130294685 | MATERIAL RECOGNITION FROM AN IMAGE - A method of operating a computer system to perform material recognition based on multiple features extracted from an image is described. A combination of low-level features extracted directly from the image and multiple novel mid-level features extracted from transformed versions of the image are selected and used to assign a material category to a single image. The novel mid-level features include non-reflectance based features such as the micro-texture features micro-jet and micro-SIFT and the shape feature curvature, and reflectance-based features including edge slice and edge ribbon. An augmented Latent Dirichlet Allocation (LDA) model is provided as an exemplary Bayesian framework for selecting a subset of features useful for material recognition of objects in an image. | 11-07-2013 |
Patent application number | Description | Published |
20100239504 | IMAGING NUCLEIC ACID BINDING PROTEINS - Reporter conjugates for non-invasive in vivo detection, e.g., imaging, of expression or activity of nucleic acid binding proteins are disclosed. The conjugates include a targeting nucleic acid linked to a reporter group, e.g., a contrast agent, such as a paramagnetic label that can be used with magnetic resonance imaging. The targeting nucleic acid can be a double-stranded nucleic acid that binds to the nucleic acid binding protein the expression of which is to be imaged. In some embodiments, the contrast agent is a chelated metal such as gadolinium or dysprosium. The invention also features methods to image protein expression in various tissues, including the brain, and therapeutic methods. | 09-23-2010 |
20110129421 | MATRIX METALLOPROTEASE TARGETING NUCLEIC ACIDS - A reporter conjugate for non-invasive detection (e.g., imaging) of matrix metalloprotease (MMP) gene expression in vivo is disclosed. The conjugate includes a targeting nucleic acid linked to a contrast agent, such as a paramagnetic label that can be used with magnetic resonance (MR) imaging. The targeting nucleic acid can be an antisense strand that hybridizes to a portion of a messenger RNA encoded by the gene whose expression is to be imaged. In some embodiments, the contrast agent is a chelated metal such as gadolinium or dysprosium. The invention also features methods to detect MMP gene expression in various tissues, including the brain. | 06-02-2011 |
20130344004 | MATRIX METALLOPROTEASE TARGETING NUCLEIC ACIDS - A reporter conjugate for non-invasive detection (e.g., imaging) of matrix metalloprotease (MMP) gene expression in vivo is disclosed. The conjugate includes a targeting nucleic acid linked to a contrast agent, such as a paramagnetic label that can be used with magnetic resonance (MR) imaging. The targeting nucleic acid can be an antisense strand that hybridizes to a portion of a messenger RNA encoded by the gene whose expression is to be imaged. In some embodiments, the contrast agent is a chelated metal such as gadolinium or dysprosium. The invention also features methods to detect MMP gene expression in various tissues, including the brain. | 12-26-2013 |
Patent application number | Description | Published |
20100305022 | LOW MOLECULAR WEIGHT HEPARIN COMPOSITION AND USES THEREOF - Preparations of low molecular weight heparins (LMWHs) having improved properties, e.g., properties that provide a clinical advantage, are provided herein. Methods of making and using such preparations as well as methods of analyzing starting materials, processing, intermediates and final products in the production of such LMWH preparations are provided. | 12-02-2010 |
20110045496 | GAL ALPHA 1-3GAL-CONTAINING N-GLYCANS IN GLYCOPROTEIN PRODUCTS DERIVED FROM CHO CELLS - The present invention provides methods of evaluating CHO cells. | 02-24-2011 |
20110136682 | ANTENNARY FUCOSYLATION IN GLYCOPROTEINS FROM CHO CELLS - The present invention provides methods of evaluating CHO cells and producing recombinant glycoproteins. | 06-09-2011 |
20110287465 | CHARACTERIZATION OF O-LINKED GLYCANS - The present disclosure provides methods for analyzing structure and/or composition of glycoproteins and glycans of glycoproteins. Such methods can include subjecting a glycoprotein preparation to a condition that removes at least one O-linked glycan from the glycoprotein. Such methods can include subjecting a glycoprotein preparation to a condition that releases an N-glycan from the glycoprotein, e.g., prior to subjecting the glycoprotein to a condition that releases an O-glycan from the glycoprotein. | 11-24-2011 |
20140045204 | EVALUATION OF COPOLYMER DIETHYLAMIDE - Methods of analyzing glatiramer acetate (GA) or a polymeric precursor thereof are provided. The methods can include determining a level of one or more diethylamide-modified amino acids in a sample comprising GA or a polymeric precursor thereof, and selecting at least a portion of the sample based on the assessment of the one or more diethylamide-modified amino acids in the sample. | 02-13-2014 |
20140045212 | GAL ALPHA 1-3GAL-CONTAINING N-GLYCANS IN GLYCOPROTEIN PRODUCTS DERIVED FROM CHO CELLS - The present invention provides methods of evaluating CHO cells. | 02-13-2014 |
20140046024 | EVALUATION OF COPOLYMER DIETHYLAMIDE - Methods of analyzing glatiramer acetate (GA) or a polymeric precursor thereof are provided. The methods can include determining a level of one or more diethylamide-modified amino acids in a sample comprising GA or a polymeric precursor thereof, and selecting at least a portion of the sample based on the assessment of the one or more diethylamide-modified amino acids in the sample. | 02-13-2014 |
Patent application number | Description | Published |
20110175770 | High Resolution SAR Imaging Using Non-Uniform Pulse Timing - A synthetic aperture radar (SAR) system includes a non-uniform pulse generator, and an echo receiver. A SAR image is reconstructed from samples of received echoes, wherein transmitted pulses and reflected echoes overlap in time. | 07-21-2011 |
20130129201 | Method for Pan-Sharpening Panchromatic and Multispectral Images Using Wavelet Dictionaries - A method Pan-sharpens a single panchromatic (Pan) image and a single multispectral (MS) image. A wavelet transform is applied to the Pan image and the MS image to obtain a wavelet transformed Pan image and a wavelet transformed MS image. Features, in the form of vectors, are extracted from the wavelet transformed Pan image and the wavelet transformed MS image. The features are separated into features without missing values and features with missing values. A dictionary is learned from features without missing values and used to predict the values for the features with the missing values. After the predicting, the features of the low frequency wavelet coefficients and the high frequency coefficients to form a fused wavelet coefficient map, and an inverse wavelet transform is applied to the fused wavelet coefficient map to obtain a fused MS image. | 05-23-2013 |
20130129207 | Method for Pan-Sharpening Panchromatic and Multispectral Images Using Dictionaries - A single panchromatic (Pan) image and a single multispectral (MS) image are Pan-sharpened by extracting features from the Pan image and the MS image. The features are decomposed into features without missing values and features with missing values. A dictionary is learned from the features without missing values. The values for the features with the missing values are learned using the dictionary. The MS image is merged with the Pan image including the predicted values into a merged image, and the merged image is then Pan sharpened. | 05-23-2013 |
20140232591 | System and Method for Multiple Spotlight Synthetic Radar Imaging Using Random Beam Steering - A spotlight synthetic aperture radar (SAR) image is generated by directing randomly a beam of transmitted pulses at a set of two or more areas using a steerable array of antennas. Each area is illuminated by an approximately equal number of the transmitted pulses. Then, a reconstruction procedure is applied independently to received signals from each area due to reflecting the transmitted pulses to generate the image corresponding to the set of areas. | 08-21-2014 |
20140266869 | Method and System for Random Steerable Sar Using Compressive Sensing - A synthetic aperture radar image is generated by directing randomly a beam of transmitted pulses at an area using a steerable array of antennas, wherein the area is uniformly by the transmitted pulses while the array of antennas moves along a path. A sparse reconstruction procedure is applied to received signals from the area due to reflecting the transmitted pulses to generate the image corresponding to the area. The radar system can operate in either sliding spotlight mode, or scan mode. The area can be of an arbitrary shape, and a resolution of the image can be increased. | 09-18-2014 |
Patent application number | Description | Published |
20110189127 | TRICYCLIC INDOLE DERIVATIVES AND METHODS OF USE THEREOF - The present invention relates to Tricyclic Indole Derivatives, compositions comprising at least one Tricyclic Indole Derivatives, and methods of using the Tricyclic Indole Derivatives for treating or preventing a viral infection or a virus-related disorder in a patient. | 08-04-2011 |
20120114739 | PYRAZOLO[1,5-a]PYRIMIDINE DERIVATIVES AS mTOR INHIBITORS - The present invention provides methods for inhibiting mTOR using pyrazolo[1,5-a]pyrimidine compounds and methods of treatment, prevention, inhibition, or amelioration of one or more diseases associated with mTOR using such compounds. | 05-10-2012 |
20120178744 | FUSED TRICYCLIC COMPOUNDS AS NOVEL mTOR INHIBITORS - The present invention provides Fused Tricyclic Compounds of the Formula (I) wherein Q, R | 07-12-2012 |
20120322791 | PYRAZOLO[1,5-a]PYRIMIDINE COMPOUNDS AS mTOR INHIBITORS - The present invention provides Pyrazolopyrimidine Compounds of Formula (I): | 12-20-2012 |
20130150353 | Fused Tricyclic Inhibitors of Mammalian Target of Rapamycin - This invention relates to novel fused tricyclic compounds that are inhibitors of mammalian Target of Rapamycin (mTOR) kinase, which is also known as FRAP, RAFT, RAPT or SEP, and are useful in the treatment of cellular proliferative diseases, for example cancer and other proliferative disorders. | 06-13-2013 |
20130150362 | NOVEL PYRAZOLO[1,5-a]PYRIMIDINE DERIVATIVES AS mTOR INHIBITORS - The present invention relates to certain pyrazolo[1,5-a]pyrimidine compounds of Formula (I) as inhibitors of mammalian Target Of Rapamycin (mTOR) kinase, which is also known as FRAP, RAFT, RAPT or SEP. The compounds may be used in the treatment of cancer and other disorders where mTOR is deregulated. The present invention further provides pharmaceutical compositions comprising the pyrazolo[1,5-a]pyrimidine compounds. | 06-13-2013 |
20140243309 | CYCLOALKYLNITRILE PYRAZOLE CARBOXAMIDES AS JANUS KINASE INHIBITORS - The instant invention provides compounds of formula I which are JAK inhibitors, and as such are useful for the treatment of JAK-mediated diseases such as rheumatoid arthritis, asthma, COPD and cancer. | 08-28-2014 |
Patent application number | Description | Published |
20090205409 | SOLVENT DELIVERY SYSTEM FOR LIQUID CHROMATOGRAPHY THAT MAINTAINS FLUID INTEGRITY AND PRE-FORMS GRADIENTS - A solvent delivery subsystem for a chromatography device performs relatively low pressure, high flow mixing of solvents to form a gradient and subsequent high pressure, low flow delivery of the gradient to the separation column. The mixing of the gradient is independent and does not interfere with the gradient delivery. To form the gradient, the outputs of an aqueous pump and an organic pump are mixed to fill a storage capillary while a downstream point from the storage capillary is vented to atmosphere. After gradient formation, the vent to atmosphere is closed, the solvent delivery system rises to high pressure, and only the aqueous pump runs for gradient delivery. To maintain integrity of the fluid stream, the solvent delivery system uses feed forward compensation and controls at least one parameter selected from the group consisting of pressure and flow in the conduit means to follow a gradual ramp. | 08-20-2009 |
20090294363 | METHODS AND APPARATUS FOR GENERATING SOLVENT GRADIENTS IN LIQUID CHROMATOGRAPHY - Embodiments of the present invention feature methods and apparatus for performing chromatographic separations. The invention feature methods and control means in the form of computer programs and software that control the formation of a concentration gradient at two or more total flow rates, with an elution period occurring in a slow flow rate and at least other portions of the gradient occurring during a fast total flow rate. | 12-03-2009 |
20100107742 | APPARATUS AND METHODS OF FLUID CHROMATOGRAPHY - The invention provides improved methods and apparatus for fluid chromatography, and is particularly appropriate to high-pressure liquid chromatography carried out using eluent flow rates less than 1 μl/minute, for example on nanoflow columns. In both single- and multi-dimensional chromatography systems, especially those comprising trapping media to facilitate injection of relatively large volumes of sample on to nanoflow columns, the on-line addition of a diluting solvent enables stronger eluents and sample solvents to be employed without causing premature release of analytes from the trapping media or the degradation of the second dimension chromatographic separation. The invention may be advantageously used for two-dimension reverse phase/reverse phase separations, especially for the separation of complex mixtures of peptides. | 05-06-2010 |
20110247403 | Apparatus And Methods For Multidimensional Analysis - The invention provides improved methods and apparatus for multidimensional analysis, especially for multidimensional liquid chromatography. Methods and apparatus for the quantitative determination of one or more components comprised in a sample mixture are described. Methods and apparatus of the invention typically allow accurate quantitative determination of more components of the mixture than prior multidimensional methods. The invention is particularly useful for, but is not limited to the analysis of complex mixtures of peptides and proteins. | 10-13-2011 |
Patent application number | Description | Published |
20090245253 | Computing Point-to-Multipoint Paths - An apparatus comprising a path computation element (PCE) configured to communicate with a path computation client (PCC) and compute a point-to-multipoint (P2MP) path across an autonomous system (AS) domain. Also included is a network component comprising at least one processor configured to implement a method comprising obtaining a computation request for a P2MP path across a plurality of AS domains, attempting to calculate the P2MP path across the AS domains, thereby generating a computed path or a failure reason, and transmitting a reply comprising the computed path or an indication of the failure reason. Included is a method comprising exchanging a request message and a reply message about a P2MP path across an AS domain between a PCC and a PCE. | 10-01-2009 |
20090252058 | Multi-Protocol Label Switching Multi-Topology Support - A network component comprising at least one processor configured to implement a method comprising receiving a packet, determining whether the packet comprises a topology label, and adding the topology label to the packet if the packet does not comprise the topology label. Included is a method comprising routing a plurality of packets corresponding to a plurality of forwarding equivalence classes (FECs) over a plurality of network topologies using a topology label and plurality of forwarding labels for each network topology. Also included is a network comprising a plurality of nodes in communication with each other and having a plurality of network topologies, wherein at least some of the nodes are configured to route data packets for a plurality of FECs along a path in each network topology using a topology label corresponding to each network topology and an inner label corresponding to each FEC. | 10-08-2009 |
20120057593 | Computing Point-to-Multipoint Paths - An apparatus comprising a path computation element (PCE) configured to communicate with a path computation client (PCC) and compute a point-to-multipoint (P2MP) path across an autonomous system (AS) domain. Also included is a network component comprising at least one processor configured to implement a method comprising obtaining a computation request for a P2MP path across a plurality of AS domains, attempting to calculate the P2MP path across the AS domains, thereby generating a computed path or a failure reason, and transmitting a reply comprising the computed path or an indication of the failure reason. Included is a method comprising exchanging a request message and a reply message about a P2MP path across an AS domain between a PCC and a PCE. | 03-08-2012 |
20120250583 | Multi-Protocol Label Switching Multi-Topology Support - A network component comprising at least one processor configured to implement a method comprising receiving a packet, determining whether the packet comprises a topology label, and adding the topology label to the packet if the packet does not comprise the topology label. Included is a method comprising routing a plurality of packets corresponding to a plurality of forwarding equivalence classes (FECs) over a plurality of network topologies using a topology label and plurality of forwarding labels for each network topology. Also included is a network comprising a plurality of nodes in communication with each other and having a plurality of network topologies, wherein at least some of the nodes are configured to route data packets for a plurality of FECs along a path in each network topology using a topology label corresponding to each network topology and an inner label corresponding to each FEC. | 10-04-2012 |
Patent application number | Description | Published |
20090136557 | Methods, Devices, And Compositions For Lysis Of Occlusive Blood Clots While Sparing Wound Sealing Clots - It has now been discovered that certain mutant forms of pro-urokinase (“pro-UK”), such as so-called pro-UK mutant “M5” (Lys.sup.300.fwdarw.His)-, perform in the manner of pro-UK in lysing “bad” blood clots (those clots that occlude blood vessels), while sparing hemostatic fibrin in the so-called “good” blood clots (those clots that seal wounds, e.g., after surgery or other tissue injury). Thus, these pro-UK mutants are excellent and safe thrombolytic agents. These advantages allow them to be used in a variety of new methods, devices, and compositions useful for thrombolysis and treating various cardiovascular disorders in clinical situations where administration of other known thrombolytic agents has been too risky or even contraindicated. | 05-28-2009 |
20090226410 | Methods, Devices, And Compositions For Lysis Of Occlusive Blood Clots While Sparing Wound Sealing Clots - It has now been discovered that certain mutant forms of pro-urokinase (“pro-UK”), such as so-called pro-UK mutant “M5” (Lys.sup.300.fwdarw.His)-, perform in the manner of pro-UK in lysing “bad” blood clots (those clots that occlude blood vessels), while sparing hemostatic fibrin in the so-called “good” blood clots (those clots that seal wounds, e.g., after surgery or other tissue injury). Thus, these pro-UK mutants are excellent and safe thrombolytic agents. These advantages allow them to be used in a variety of new methods, devices, and compositions useful for thrombolysis and treating various cardiovascular disorders in clinical situations where administration of other known thrombolytic agents has been too risky or even contraindicated. | 09-10-2009 |
20100234274 | Use of Nestafin-1 in the Treatment for Diabetes - The present invention provides a method of treating diabetes by increasing peripheral nesfatin-1. Peripheral nesfatin-1 can be increased by administration of nesfatin-1, conjugated nesfatin-1 that would not penetrate the blood-brain barrier, or plasmin inhibitors. The present invention also provides a method of screening for an agent that would increase peripheral or brain nesfatin-1. | 09-16-2010 |
20100235935 | PLASMA ANTI-DIABETIC NUCB2 PEPTIDE (PLADIN) AND USES THEREOF - The present invention provides pladin (plasma anti-diabetic nucb2 peptide) polypeptide and functional equivalent thereof that are useful for treating diabetes. The present invention provides a method of treating diabetes by administering to a subject nesfatin-1, pladin, or a functional equivalent thereof. The present invention also provides a method of treating diabetes by administering to subject plasmin inhibitors. | 09-16-2010 |
20140005105 | PLASMA ANTI-DIABETIC NUCB2 PEPTIDE (PLADIN) AND USES THEREOF | 01-02-2014 |
Patent application number | Description | Published |
20100158476 | Methods, Systems and Computer Program Products for Local DVR Scheduling Conflict Management - This disclosure details the implementation of methods, systems and computer program products for local DVR scheduling conflict management (hereinafter, “SCM”). SCM systems allow for automatic organization, prioritization, and conflict resolution for multiple scheduled recording specifications. Conflicting scheduled recordings may be re-organized based on single-stage and/or multi-stage conflict resolution procedures. Embodiments of SCM systems may also implement weighted conflict resolution, wherein user preferences and/or prioritizations may be assigned to scheduled recordings and considered in the re-organization of conflicting recordings. In one embodiment, a method is disclosed, comprising: receiving a new scheduled recording instruction comprising at least a new program identifier and a new time; comparing the new scheduled recording instruction to an existing recording schedule to determine if a recording conflict exists; performing a conflict resolution for an existing conflict to yield a new recording schedule; and storing the new recording schedule in a scheduling database. | 06-24-2010 |
20100319048 | PUBLICATION OF TELEVISION CONTENT TO TELEVISION DISTRIBUTION SITES - A device receives updated television content, and generates a file that provides an indication to copy the updated television content to multiple television distribution sites, where each television distribution site includes multiple television distribution devices. The device identifies one of the multiple television distribution devices, associated with each of the multiple television distribution sites, to receive the file, packages the updated television content with the file, for the identified one of the multiple television distribution devices, and provides the updated television content and the file to the identified one of the multiple television distribution devices. | 12-16-2010 |
20110099488 | METHOD AND APPARATUS FOR PRESENTING VIDEO ASSETS - An approach is provided for presenting video assets. An asset manager determines a plurality of factors for positioning of video assets represented on a graphical user interface. The asset manager then determines weighting of the factors using one or more rules that are based on a search operation or a browse operation relating to the assets. From the determined plurality of factors and weighting of the factors, the asset manager computes a score for ranking of a particular one of the assets with respect to the positioning of other ones of the assets. | 04-28-2011 |
20110131594 | BOOSTING FACTOR FOR TELEVISION CONTENT - A method includes receiving viewership data associated with television contents; calculating one or more local boosting factors and a national boosting factor for each of the television contents based on the viewership data; applying boosting factor assignment heuristics to the one or more local and national boosting factors for each of the television contents; selecting one or more boosting factors based the applying of the boosting factor assignment heuristics for each of the television contents; and publishing the one or more boosting factors to one or more television distribution sites for each of the television contents. | 06-02-2011 |
20120159543 | AUTOMATED QUERY GENERATION FOR TELEVISON CONTENT SEARCHING - A system is configured to receive a portion of a word; retrieve a group of words matching the portion of the word; retrieve information associated with a set of words in the group, where the information, for a particular one of the words, indicates a measure of popularity of the particular word, geographic location information associated with the particular word, time information associated with the particular word, or user preference information associated with the particular word; rank the set of words based on the information; present a list of words from the set of words for display based on the ranking; receive selection of a word from the list of words; perform a search for television content based on the selected word to identify a group of television content; receive selection of television content from the group of television content; and present the selected television content for display. | 06-21-2012 |
Patent application number | Description | Published |
20100260668 | Dual Variable Domain Immunoglobulins and Uses Thereof - The present invention relates to engineered multivalent and multispecific binding proteins, methods of making, and specifically to their uses in the prevention, diagnosis, and/or treatment of disease. | 10-14-2010 |
20110008766 | Dual Variable Domain Immunoglobulins and Uses Thereof - Engineered multivalent and multispecific binding proteins, methods of making, and specifically to their uses in the prevention, diagnosis, and/or treatment of disease. | 01-13-2011 |
20110044980 | Dual Variable Domain Immunoglobulins and Uses Thereof - The present invention relates to engineered multivalent and multispecific binding proteins, methods of making, and specifically to their uses in the prevention, diagnosis, and/or treatment of disease. | 02-24-2011 |
20110091372 | Dual Variable Domain Immunoglobulins and Uses Thereof - The present invention relates to engineered multivalent and multispecific binding proteins, methods of making, and specifically to their uses in the prevention, diagnosis, and/or treatment of disease. | 04-21-2011 |
20110212094 | DUAL VARIABLE DOMAIN IMMUNOGLOBULINS AND USES THEREOF - The present invention relates to engineered multivalent and multispecific binding proteins, methods of making, and specifically to their uses in the prevention, diagnosis, and/or treatment of disease. | 09-01-2011 |
20110263827 | Dual Variable Domain Immunnoglobulins and Uses Thereof - The present invention relates to engineered multivalent and multispecific binding proteins, methods of making, and specifically to their uses in the prevention, diagnosis, and/or treatment of disease. | 10-27-2011 |
20110318349 | DUAL VARIABLE DOMAIN IMMUNOGLOBULINS AND USES THEREOF - The present invention relates to engineered multivalent and multispecific binding proteins, methods of making, and specifically to their uses in the prevention, diagnosis, and/or treatment of disease. | 12-29-2011 |
20120014957 | DUAL VARIABLE DOMAIN IMMUNOGLOBULINS AND USES THEREOF - Engineered multivalent and multispecific binding proteins, methods of making, and specifically to their uses in the prevention, diagnosis, and/or treatment of disease are provided. | 01-19-2012 |
20120201746 | HALF IMMUNOGLOBULIN BINDING PROTEINS AND USES THEREOF - The invention provides compositions, methods, and kits related to half-Ig binding proteins that include a functional antibody binding site and a CH3 domain wherein the CH3 domain includes at least one mutation to inhibit CH3-CH3 dimerization. | 08-09-2012 |
20120258108 | Dual Variable Domain Immunoglobulins and Uses Thereof - Engineered multivalent and multispecific binding proteins, methods of making, and their uses in the prevention, diagnosis, and/or treatment of disease are provided. | 10-11-2012 |
20120263722 | Dual Variable Domain Immunoglobulins and Uses Thereof - Engineered multivalent and multispecific binding proteins, methods of making, and their uses in the prevention, diagnosis, and/or treatment of disease are provided. | 10-18-2012 |
20130171059 | DUAL VARIABLE DOMAIN IMMUNOGLOBULINS AND USES THEREOF - Multivalent and multispecific binding proteins, methods of making, and their uses in the diagnosis, prevention, and/or treatment diseases are provided. | 07-04-2013 |
20140134171 | Dual Variable Domain Immunoglobulins and Uses Thereof - The present invention relates to engineered multivalent and multispecific binding proteins, methods of making, and specifically to their uses in the prevention, diagnosis, and/or treatment of disease. | 05-15-2014 |
20140186377 | PROSTAGLANDIN E2 BINDING PROTEINS AND USES THEREOF - The present invention encompasses prostaglandin E | 07-03-2014 |
20140219912 | DUAL VARIABLE DOMAIN IMMUNOGLOBULINS AND USES THEREOF - Engineered multivalent and multispecific binding proteins, methods of making, and their uses in the prevention, diagnosis, and/or treatment of disease are provided. | 08-07-2014 |
20140220019 | DUAL VARIABLE DOMAIN IMMUNOGLOBULINS AND USES THEREOF - Engineered multivalent and multispecific binding proteins, methods of making, and their uses in the prevention, diagnosis, and/or treatment of disease are provided. | 08-07-2014 |
20140234208 | DUAL VARIABLE DOMAIN IMMUNOGLOBULINS AND USES THEREOF - Engineered multivalent and multispecific binding proteins, methods of making, and their uses in the prevention, diagnosis, and/or treatment of disease are provided. | 08-21-2014 |
20140308286 | DUAL VARIABLE DOMAIN IMMUNOGLOBULINS AND USES THEREOF - The present invention relates to engineered multivalent and multispecific binding proteins, methods of making, and specifically to their uses in the prevention, diagnosis, and/or treatment of disease. | 10-16-2014 |
20150038337 | METHODS OF SELECTING BIOLOGIC-PRODUCING CELL LINES BY NEXT GENERATION SEQUENCING - An optimized multi-step cell line screening method based on next generation sequencing (NGS) and mass spec (MS) is disclosed. The method helps reduce variants in the biologic-producing cell line and improve the efficiency of cell line development process. | 02-05-2015 |
Patent application number | Description | Published |
20110218403 | SYSTEMS, METHODS AND COMPUTER-ACCESSIBLE MEDIUM WHICH PROVIDE MICROSCOPIC IMAGES OF AT LEAST ONE ANATOMICAL STRUCTURE AT A PARTICULAR RESOLUTION - Exemplary embodiments of probes, apparatus, systems and methods can be provided which provide at least one electro-magnetic radiation to at least one sample. For example, a plurality of axicon lenses can be provided which are configured to provide the electro-magnetic radiation(s) having at least partially annulus shape. In addition or alternatively, at least one optical arrangement can be provided which is configured to forward at least one radiation to the sample therethrough having at least partially circularly-symmetric pattern. For example, at least one first portion of the radiation transmitted through a circular section of the pattern can have an optical path-length that is different from an optical path-length of at least one second portion of the radiation transmitted through at least one other section of the pattern. | 09-08-2011 |
20110261366 | SYSTEMS, METHODS AND COMPUTER-ACCESSIBLE MEDIUM WHICH PROVIDE MICROSCOPIC IMAGES OF AT LEAST ONE ANATOMICAL STRUCTURE AT A PARTICULAR RESOLUTION - Exemplary embodiments of systems and methods can be provided which can generate data associated with at least one portion of a sample. For example, at least one first radiation can be forwarded to the portion through at least one optical arrangement. At least one second radiation can be received from the portion which is based on the first radiation. Based on an interaction between the optical arrangement and the first radiation and/or the second radiation, the optical arrangement can have a first transfer function. Further, it is possible to forward at least one third radiation to the portion through such optical arrangement (or through another optical arrangement), and receive at least one fourth radiation from the portion which is based on the third radiation. Based on an interaction between the optical arrangement (or the other optical arrangement) and the third radiation and/or the fourth radiation, the optical arrangement (or the other optical arrangement) can have a second transfer function. The first transfer function can be at least partially different from the second transfer function. The data can be generated based on the second and fourth radiations. | 10-27-2011 |
20120008146 | Systems, Methods and Computer-Accessible Medium Which Provide Microscopic Images of at Least One Anatomical Structure at a Particular Resolution - Exemplary embodiments of apparatus, systems and methods can be provided for providing at least one electro-magnetic radiation to at least one sample. For example, a plurality of wave-guiding arrangements can be provided which are configured to (i) provide the electro-magnetic radiation(s), and (ii) at a point of emission of each of the wave guiding arrangements, cause a phase of each of the electro-magnetic radiation(s) to have a predetermined value. The exemplary apparatus can be part of a probe. Further the exemplary apparatus can include an interferometric arrangement provided in communication with the probe and/or be part of the probe. | 01-12-2012 |
Patent application number | Description | Published |
20100239504 | IMAGING NUCLEIC ACID BINDING PROTEINS - Reporter conjugates for non-invasive in vivo detection, e.g., imaging, of expression or activity of nucleic acid binding proteins are disclosed. The conjugates include a targeting nucleic acid linked to a reporter group, e.g., a contrast agent, such as a paramagnetic label that can be used with magnetic resonance imaging. The targeting nucleic acid can be a double-stranded nucleic acid that binds to the nucleic acid binding protein the expression of which is to be imaged. In some embodiments, the contrast agent is a chelated metal such as gadolinium or dysprosium. The invention also features methods to image protein expression in various tissues, including the brain, and therapeutic methods. | 09-23-2010 |
20110129421 | MATRIX METALLOPROTEASE TARGETING NUCLEIC ACIDS - A reporter conjugate for non-invasive detection (e.g., imaging) of matrix metalloprotease (MMP) gene expression in vivo is disclosed. The conjugate includes a targeting nucleic acid linked to a contrast agent, such as a paramagnetic label that can be used with magnetic resonance (MR) imaging. The targeting nucleic acid can be an antisense strand that hybridizes to a portion of a messenger RNA encoded by the gene whose expression is to be imaged. In some embodiments, the contrast agent is a chelated metal such as gadolinium or dysprosium. The invention also features methods to detect MMP gene expression in various tissues, including the brain. | 06-02-2011 |
20130344004 | MATRIX METALLOPROTEASE TARGETING NUCLEIC ACIDS - A reporter conjugate for non-invasive detection (e.g., imaging) of matrix metalloprotease (MMP) gene expression in vivo is disclosed. The conjugate includes a targeting nucleic acid linked to a contrast agent, such as a paramagnetic label that can be used with magnetic resonance (MR) imaging. The targeting nucleic acid can be an antisense strand that hybridizes to a portion of a messenger RNA encoded by the gene whose expression is to be imaged. In some embodiments, the contrast agent is a chelated metal such as gadolinium or dysprosium. The invention also features methods to detect MMP gene expression in various tissues, including the brain. | 12-26-2013 |
Patent application number | Description | Published |
20110014170 | NOVEL ALPHA-GALACTOSIDASES - This invention relates to novel α-galactosidases for the enzymatic removal of the immunodominant monosaccharides on blood products and tissues. Specifically this invention provides a novel family of α3 glycosidases, used for the enzymatic removal of type B antigens from blood group B and AB reactive blood products, and the Galili antigen from non-human animal tissues, thereby converting these to non-immunogenic cells and tissues suitable for transplantation. | 01-20-2011 |
20110045569 | ENZYMATIC CONVERSION OF BLOOD GROUP A, B, AND AB RED BLOOD CELLS USING ALPHA-N- ACETYLGALACTOSAMINIDASES AND ALPHA-GALACTOSIDASES WITH UNIQUE SUBSTRATE SPECIFICITIES AND KINETIC PROPERTIES - This invention relates to enzymatic removal of type A and B antigens from blood group A, B, and AB reactive cells in blood products, and thereby converting these to non-A and non-B reactive cells. The invention further relates to using unique α-N-acetylgalactosaminidases and α-galactosidases with superior kinetic properties for removing the immunodominant monosaccharides of the blood group A and B antigens and improved performance in enzymatic conversion of red blood cells. The preferred unique α-N-acetylgalactosaminidases and α-galactosidases exhibit the following characteristics: (i) exclusive, preferred or no less than 10% substrate specificity for the type A and B branched polysaccharide structures relative to measurable activity with simple mono- and disaccharide structures and aglycon derivatives hereof; (ii) optimal performance at neutral pH with blood group oligosaccharides and in enzymatic conversion of cells; and (iii) a favorable kinetic constant K | 02-24-2011 |
20120202273 | Enzymatic Conversion Of Blood Group A, B, And AB Red Blood Cells Using Alpha-N-Acetylgalactosaminidases and Alpha-Galactosidases With Unique Substrate Specificities And Kinetic Properties - This invention relates to enzymatic removal of type A and B antigens from blood group A, B, and AB reactive cells in blood products, and thereby converting these to non-A and non-B reactive cells. The invention further relates to using unique α-N-acetylgalactosaminidases and α-galactosidases with superior kinetic properties for removing the immunodominant monosaccharides of the blood group A and B antigens and improved performance in enzymatic conversion of red blood cells. The preferred unique α-N-acetylgalactosaminidases and α-galactosidases exhibit the following characteristics: (i) exclusive, preferred or no less than 10% substrate specificity for the type A and B branched polysaccharide structures relative to measurable activity with simple mono- and disaccharide structures and aglycon derivatives hereof; (ii) optimal performance at neutral pH with blood group oligosaccharides and in enzymatic conversion of cells; and (iii) a favorable kinetic constant K | 08-09-2012 |
20120294842 | Platelet Additive Solution Having a Sialidase Inhibitor - The present invention relates to a platelet additive solution (PAS) having an amount of one or more sialidase inhibitors and optionally one or more glycan-modifying agents; and one or more of PAS components that includes a salt, a citrate source, a carbon source, and any combination thereof. | 11-22-2012 |
20120321601 | Increased In Vivo Circulation Time of Platelets After Storage With A Sialidase Inhibitor - The present invention relates to methods, compositions and kits for increasing the in vivo circulation time of isolated platelets by storing the platelets with one or more sialidase inhibitors. | 12-20-2012 |
20120321722 | Platelet Storage and Reduced Bacterial Proliferation In Platelet Products Using A Sialidase Inhibitor - The present invention relates to methods and compositions for reducing sialidase activity and inhibiting bacterial proliferation of one or more bacteria in a platelet product preparation from one or more donors. In general, the method includes contacting the platelet product preparation with an amount of a sialidase inhibitor, to thereby obtain a sialidase inhibitor-treated platelet product preparation. Sialidase activity is reduced and the proliferation of one or more bacteria is inhibited, as compared to a platelet product preparation not subjected to the sialidase inhibitor treatment. | 12-20-2012 |
20140099629 | Platelet Additive Solution Having a beta-Galactosidase Inhibitor - The present invention relates to a platelet additive solution (PAS) having an amount of one or more β-galactosidase inhibitors with or without an amount of one or more sialidase inhibitors, and optionally one or more glycan-modifying agents; and one or more of PAS components that include a salt, a citrate source, a carbon source, or any combination thereof. | 04-10-2014 |
20140220553 | Enzymatic Conversion of Blood Group A, B, and AB Red Blood Cells Using alpha-N-Acetylgalactosaminidases and alpha-Galactosidases with Unique Substrate Specificities and Kinetic Properties - This invention relates to enzymatic removal of type A and B antigens from blood group A, B, and AB reactive cells in blood products, and thereby converting these to non-A and non-B reactive cells. The invention further relates to using unique α-N-acetylgalactosaminidases and α-galactosidases with superior kinetic properties for removing the immunodominant monosaccharides of the blood group A and B antigens and improved performance in enzymatic conversion of red blood cells. The preferred unique α-N-acetylgalactosaminidases and α-galactosidases exhibit the following characteristics: (i) exclusive, preferred or no less than 10% substrate specificity for the type A and B branched polysaccharide structures relative to measurable activity with simple mono- and disaccharide structures and aglycon derivatives hereof: (ii) optimal performance at neutral pH with blood group oligosaccharides and in enzymatic conversion of cells: and (iii) a favorable kinetic constant Km with mono- and oligosaccharide substrates. The conversion methods of the invention use significantly lower amounts of recombinant glycosidase enzymes than previous and result in complete sera-conversion of all blood group A and B red cells. | 08-07-2014 |
20150087061 | Methods of Preparing Tissues for Xenotransplantation Using Alpha-galactosidases - This invention relates to novel α-galactosidases for the enzymatic removal of the immunodominant monosaccharides on blood products and tissues. Specifically this invention provides a novel family of α3 glycosidases, used for the enzymatic removal of type B antigens from blood group B and AB reactive blood products, and the Galili antigen from non-human animal tissues, thereby converting these to non-immunogenic cells and tissues suitable for transplantation. | 03-26-2015 |
Patent application number | Description | Published |
20110312147 | TRANSISTOR STRUCTURE WITH A SIDEWALL-DEFINED INTRINSIC BASE TO EXTRINSIC BASE LINK-UP REGION AND METHOD OF FORMING THE TRANSISTOR - Disclosed are embodiments of a bipolar or heterojunction bipolar transistor and a method of forming the transistor. The transistor can incorporate a dielectric layer sandwiched between an intrinsic base layer and a raised extrinsic base layer to reduce collector-base capacitance C | 12-22-2011 |
20120112244 | VERTICAL HETEROJUNCTION BIPOLAR TRANSISTORS WITH REDUCED BASE-COLLECTOR JUNCTION CAPACITANCE - Vertical heterojunction bipolar transistors with reduced base-collector junction capacitance, as well as fabrication methods for vertical heterojunction bipolar transistors and design structures for BiCMOS integrated circuits. The vertical heterojunction bipolar transistor includes a barrier layer between the intrinsic base and the extrinsic base that blocks or reduces diffusion of a dopant from the extrinsic base to the intrinsic base. The barrier layer has at least one opening that permits direct contact between the intrinsic base and a portion of the extrinsic base disposed in the opening. | 05-10-2012 |
20120126292 | HETEROJUNCTION BIPOLAR TRANSISTORS WITH REDUCED BASE RESISTANCE - Heterojunction bipolar transistors with reduced base resistance, as well as fabrication methods for heterojunction bipolar transistors and design structures for BiCMOS integrated circuits. The heterojunction bipolar transistor includes a conductive layer between the intrinsic base and the extrinsic base. The conductive layer is comprised of a conductive material, such as a silicide, having a lower resistivity than the materials forming the intrinsic base and the extrinsic base. | 05-24-2012 |
20120146098 | DEVICE ISOLATION WITH IMPROVED THERMAL CONDUCTIVITY - A method of making a semiconductor structure includes forming a trench through a shallow trench isolation (STI) structure and into a substrate, and forming a liner including an electrical insulator material on sidewalls of the trench. The method also includes forming a core including a high thermal conductivity material in the trench and on the liner, and forming a cap in the trench and on the core. | 06-14-2012 |
20120221987 | VERTICAL HETEROJUNCTION BIPOLAR TRANSISTORS WITH REDUCED BASE-COLLECTOR JUNCTION CAPACITANCE - Vertical heterojunction bipolar transistors with reduced base-collector junction capacitance, as well as fabrication methods for vertical heterojunction bipolar transistors and design structures for BiCMOS integrated circuits. The vertical heterojunction bipolar transistor includes a barrier layer between the intrinsic base and the extrinsic base that blocks or reduces diffusion of a dopant from the extrinsic base to the intrinsic base. The barrier layer has at least one opening that permits direct contact between the intrinsic base and a portion of the extrinsic base disposed in the opening. | 08-30-2012 |
20120228611 | BIPOLAR JUNCTION TRANSISTOR WITH A SELF-ALIGNED EMITTER AND BASE - Methods for fabricating bipolar junction transistors with self-aligned emitter and extrinsic base, bipolar junction transistors made by the methods, and design structures for a BiCMOS integrated circuit. The bipolar junction transistor is fabricated using a sacrificial emitter pedestal that provides a sacrificial mandrel promoting self-alignment between the emitter and the extrinsic base. The sacrificial emitter pedestal is subsequently removed to open an emitter window extending to the intrinsic base. An emitter is formed in the emitter window that lands on the intrinsic base. | 09-13-2012 |
20130009280 | BIPOLAR JUNCTION TRANSISTORS WITH A LINK REGION CONNECTING THE INTRINSIC AND EXTRINSIC BASES - Methods for fabricating bipolar junction transistors, bipolar junction transistors made by the methods, and design structures for a bipolar junction transistor. The bipolar junction transistor includes a dielectric layer on an intrinsic base and an extrinsic base at least partially separated from the intrinsic base by the dielectric layer. An emitter opening extends through the extrinsic base and the dielectric layer. The dielectric layer is recessed laterally relative to the emitter opening to define a cavity between the intrinsic base and the extrinsic base. The cavity is filled with a semiconductor layer that physically links the extrinsic base and the intrinsic base together. | 01-10-2013 |
20130062668 | HETEROJUNCTION BIPOLAR TRANSISTORS WITH REDUCED BASE RESISTANCE - Heterojunction bipolar transistors with reduced base resistance, as well as fabrication methods for heterojunction bipolar transistors and design structures for BiCMOS integrated circuits. The heterojunction bipolar transistor includes a conductive layer between the intrinsic base and the extrinsic base. The conductive layer is comprised of a conductive material, such as a silicide, having a lower resistivity than the materials forming the intrinsic base and the extrinsic base. | 03-14-2013 |
20130140566 | BIPOLAR JUNCTION TRANSISTOR WITH A SELF-ALIGNED EMITTER AND BASE - Methods for fabricating bipolar junction transistors with self-aligned emitter and extrinsic base, bipolar junction transistors made by the methods, and design structures for a BiCMOS integrated circuit. The bipolar junction transistor is fabricated using a sacrificial emitter pedestal that provides a sacrificial mandrel promoting self-alignment between the emitter and the extrinsic base. The sacrificial emitter pedestal is subsequently removed to open an emitter window extending to the intrinsic base. An emitter is formed in the emitter window that lands on the intrinsic base. | 06-06-2013 |
20130147017 | BIPOLAR JUNCTION TRANSISTORS WITH A LINK REGION CONNECTING THE INTRINSIC AND EXTRINSIC BASES - Methods for fabricating bipolar junction transistors, bipolar junction transistors made by the methods, and design structures for a bipolar junction transistor. The bipolar junction transistor includes a dielectric layer on an intrinsic base and an extrinsic base at least partially separated from the intrinsic base by the dielectric layer. An emitter opening extends through the extrinsic base and the dielectric layer. The dielectric layer is recessed laterally relative to the emitter opening to define a cavity between the intrinsic base and the extrinsic base. The cavity is filled with a semiconductor layer that physically links the extrinsic base and the intrinsic base together. | 06-13-2013 |
20130149832 | TRANSISTOR STRUCTURE WITH A SIDEWALL-DEFINED INTRINSIC BASE TO EXTRINSIC BASE LINK-UP REGION AND METHOD OF FORMING THE TRANSISTOR - Disclosed are embodiments of a bipolar or heterojunction bipolar transistor and a method of forming the transistor. The transistor can incorporate a dielectric layer sandwiched between an intrinsic base layer and a raised extrinsic base layer to reduce collector-base capacitance C | 06-13-2013 |
Patent application number | Description | Published |
20090075915 | 6,11-BICYCLOLIDES: BRIDGED BIARYL MACROLIDE DERIVATIVES - The present invention discloses compounds of formula I, or pharmaceutically acceptable salts, esters, or prodrugs thereof: | 03-19-2009 |
20090118506 | 6,11-BRIDGED BIARYL MACROLIDES - The present invention discloses compounds of formula I, II or, or pharmaceutically acceptable salts, esters, or prodrugs thereof: | 05-07-2009 |
20090264380 | 6,11-BRIDGED BIARYL MACROLIDES - The present invention discloses compounds of formula I, II or X, or pharmaceutically acceptable salts, esters, or prodrugs thereof: | 10-22-2009 |
20090270457 | 6,11-BICYCLOLIDES: BRIDGED BIARYL MACROLIDE DERIVATIVES - The present invention discloses compounds of formula I, or pharmaceutically acceptable salts, esters, or prodrugs thereof: | 10-29-2009 |
20090324577 | 6-11 Bicyclic Ketolide Derivatives - The present invention discloses compounds of formula I, or pharmaceutically acceptable salts, esters, or prodrugs thereof: | 12-31-2009 |
20120035352 | 6-11 Bicyclic Ketolide Derivatives - The present invention discloses compounds of formula I, or pharmaceutically acceptable salts, esters, or prodrugs thereof: | 02-09-2012 |
Patent application number | Description | Published |
20110072137 | INTEGRATED APPLICATION ACCESS - An integration portal provides a user with access to application entities of a plurality of remote applications. An authorization layer included in the integration portal includes a permission map indicating an association between the user and at least one of the application entities of the plurality of remote applications that the user is permitted to access. The authorization layer in the integration portal is synchronized with an authorization layer included in an application portal that provides the user with access to a subset of the remote applications, whereby the permission map is updated with information about at least one of the application entities that the user is permitted to access through the integration portal. Corresponding systems and methods are also disclosed. | 03-24-2011 |
20120011164 | LIFE CYCLE BASED DATA COORDINATION - A system may include a data store storing global data mapped from local data maintained by a plurality of heterogeneous data subsystems. The system may further include a life cycle coordinator including a global data life cycle model defining at least one life cycle for the global data, said life cycle coordinator being configured to receive a data update message defined in accordance with the global data life cycle model and representative of an update of the local data of one of the heterogeneous data subsystems, the data update message including a life cycle status identifier of a data record associated with the update, translate the data update message to at least one global data operation, the translation being based at least in part on the life cycle status identifier, and apply the update to the global data by performing the at least one global data operation | 01-12-2012 |
20120023074 | SCALABLE RULE-BASED DATA SYNCHRONIZATION SYSTEMS AND METHODS - Exemplary scalable, rule-based data synchronization systems and methods are disclosed. An exemplary method includes at least one computing device executing a database trigger process in response to a database trigger event, the database trigger process including writing a general data message to a general message repository. The method further includes the at least one computing device executing an independent process including monitoring the general message repository, detecting the general data message in the general message repository, and processing, in response to the detecting of the general data message in the general message repository, the general data message in accordance with a predefined set of rules. Corresponding systems and methods are also disclosed. | 01-26-2012 |
Patent application number | Description | Published |
20090119348 | DATA STRUCTURE VERSIONING FOR DATA MANAGEMENT SYSTEMS AND METHODS - In one of many possible implementations, an exemplary system includes a data integration subsystem configured to maintain a baseline data structure representing a base set of data relationships. The data integration subsystem in further configure to maintain a mapping of the baseline data structure to local data maintained by a plurality of local data subsystems. The system further includes a portal subsystem configured to provide a first customizable data structure associated with the baseline data structure for user access, create a copy of at least a subset of the baseline data structure, and provide a second customizable data structure associated with the copy of the baseline data structure for user access. The first and second customizable data structures are independently customizable to represent different custom sets of data relationships. | 05-07-2009 |
20090248714 | SELECTIVE MAPPING OF INTEGRATED DATA - In one of many possible implementations, an exemplary system includes a plurality of data subsystems configured to store local data associated with an external party, the data subsystems configured to be maintained by an internal party. The system further includes a data integration subsystem configured to store global data and a defined mapping of the global data to the local data, the global data including a global data record mapped to a local data record having a first data schema type, recognize a migration event in the local data, the migration event including migration of the first schema type local data record to a second schema type local data record, and associate a smart mapping record with the global data record, the smart mapping record configured to selectively map the global data record to one of the first schema type local data record and the second schema type local data record. | 10-01-2009 |
20110208781 | DATA STRUCTURE VERSIONING FOR DATA MANAGEMENT SYSTEMS AND METHODS - In one of many possible implementations, an exemplary method comprises maintaining a baseline data structure comprising a plurality of baseline data records and a base set of relationships between the baseline data records, providing, for access by an external party, a customizable data structure comprising copies of the baseline data records and a customizable set of relationships between the copies of the baseline data records, fixing the base set of relationships in the baseline data structure to be unchangeable by the external party, and defining the customizable set of relationships in the customizable data structure to be changeable by the external party. Corresponding systems and methods are also disclosed. | 08-25-2011 |
Patent application number | Description | Published |
20100038303 | Disposable polymer-structured filtering kit - The disposable polymer-structured filtering kit includes a disposable, polymer-structured filtering funnel with a stem having a distal tip. A flow discharge end is formed at the distal tip. Preferably, a polymer fritted filter disc is positioned in the funnel, providing filtering for liquids passing therethrough. The kit preferably also includes a glass vacuum take-off adapter having a port for connecting to a vacuum source for providing negative pressure. The adapter securely and snuggly receives the funnel and maintains position of the distal tip thereof with the flow discharge end below the port, thus preventing contaminants from entering the adapter. A reusable, glass round bottle flask or a disposable vial receives the adapter and the stem of the funnel. The funnel and fritted disc are formed from disposable materials, thus removing the necessity of cleaning them following use. The adapter is reusable, since no contaminants come in contact therewith during filtering. | 02-18-2010 |
20100160258 | Bicyclic aryl sphingosine 1-phosphate analogs - Compounds that have agonist activity at one or more of the S1P receptors are provided. The compounds are sphingosine analogs that, after phosphorylation, can behave as agonists at S1P receptors. | 06-24-2010 |
20100160357 | Heterobicyclic sphingosine 1-phosphate analogs - Compounds that have agonist activity at one or more of the S1P receptors are provided. The compounds are sphingosine analogs that, after phosphorylation, can behave as agonists at S1P receptors. | 06-24-2010 |
20120190649 | BICYCLIC ARYL SPHINGOSINE 1-PHOSPHATE ANALOGS - Compounds that have agonist activity at one or more of the S1P receptors are provided. The compounds are sphingosine analogs that, after phosphorylation, can behave as agonists at S1P receptors. | 07-26-2012 |
20130059821 | BICYCLIC ARYL SPHINGOSINE 1-PHOSPHATE ANALOGS - Compounds that have agonist activity at one or more of the SIP receptors are provided. The compounds are sphingosine analogs that, after phosphorylation, can behave as agonists at SIP receptors. | 03-07-2013 |
20130319958 | MULTI-FUNCTIONAL DISPOSABLE SEPARATORY FUNNELS - This invention incorporates barrel-shaped polymer-structured separatory funnels. The separatory funnels are made from an injection molding machine using cheaper plastic resins such as polypropylene, or polyethylene instead of glass in order to lower costs, so they are ready-to-use and disposable. The innovative separatory funnels have multi-functional features, which can be used as regular separatory funnels for liquid-liquid phase separation and extraction, as receiving receptacles to take the filtrate in a solid-liquid filtration apparatus, and also as flasks hooked in a rotary evaporator to evaporate solvents. | 12-05-2013 |
20140309190 | BICYCLIC ARYL SPHINGOSINE 1-PHOSPHATE ANALOGS - Compounds that have agonist activity at one or more of the S | 10-16-2014 |
Patent application number | Description | Published |
20100295225 | METHOD AND APPARATUS FOR FLUID PROCESSING A WORKPIECE - A method of fluid sealing a workpiece is provided. The method includes placing a workpiece on a ring, engaging at least one engagement feature of the ring with at least one retaining feature defined by the member and flexing the member to provide a force to the at least one engagement feature to cause the ring to form a barrier to fluid entry with the workpiece. | 11-25-2010 |
20100301564 | BALANCING PRESSURE TO IMPROVE A FLUID SEAL - A method of fluid sealing a workpiece is provided. The method includes providing a force to cause a ring to form a barrier to fluid entry with the workpiece and preventing fluid from crossing the barrier to fluid entry by forming a pressure differential across the barrier. | 12-02-2010 |
20110139627 | METHOD AND APPARATUS FOR FLUID PROCESSING A WORKPIECE - A method of fluid processing a semiconductor workpiece, including disposing a workpiece holder with a housing capable of containing a fluid, the workpiece holder retaining the workpiece, providing an agitation system connected to the housing and comprising a member disposed within the housing adjacent the workpiece holder, and agitating the fluid by moving the member substantially parallel to a surface of the workpiece with a non-uniform oscillatory motion, the non-uniform oscillatory motion being a series of substantially continuous geometrically asymmetric oscillations wherein each consecutive oscillation of the series is geometrically asymmetric having at least two substantially continuous opposing strokes wherein reversal positions of each substantially continuous stroke of the substantially continuous asymmetric oscillation are disposed asymmetrically with respect to a center point of each immediately preceding substantially continuous stroke of the oscillation. | 06-16-2011 |
20110240481 | SEED LAYER DEPOSITION IN MICROSCALE FEATURES - A method and system for coating the interior surfaces of microscale hole features fabricated into the substantially planar surface of a work piece. The method comprises providing a work piece with a barrier metal coating that is substantially continuous and uniform both along the planar surface of the work piece and the inner surfaces of the microscale hole features wherein said barrier metal coating is applied by a substantially surface reaction limited process. The workpiece is provided with a coating, on the planar surface of the work piece, of a thick metal layer anchored to the barrier metal coat and disposed to provide substantially uniform electrical conduction capability to the microscale features located throughout and across the workpiece. An electrical contact path is provided to the electrically conductive coating at the perimeter of the work piece. The workpiece is immersed in a chemical bath, causing said chemical bath to fully contact the interior surfaces of the microscale hole features, said chemical bath containing metal ions suitable for electrodeposition. An electric potential is applied at the perimeter of the work piece to cause electrodeposition of metal ions onto all surfaces of the work piece including the interior surfaces of the microscale hole features to a predetermined finish coating in one step. | 10-06-2011 |
20120103799 | METHOD AND APPARATUS FOR FLUID PROCESSING A WORKPIECE - A workpiece holder for fluid processing a workpiece including a transportable frame, a flexible member connected to the frame and defining at least one retaining feature, and a ring comprising at least one engagement feature engageable with the at least one retaining feature of the flexible member, wherein the flexible member is flexed to provide a force to the at least one engagement feature to cause the ring to form a barrier to fluid entry with the workpiece. | 05-03-2012 |
20120152752 | SEED LAYER DEPOSITION IN MICROSCALE FEATURES - A method of forming a metal feature on a workpiece with deposition is provided. The method includes providing an under bump metal layer for solder of an electronic device on the workpiece, depositing a substantially pure tin layer directly to the under bump metal layer, and depositing a tin silver alloy layer onto the substantially pure tin layer. | 06-21-2012 |
20120325671 | ELECTROPLATED LEAD-FREE BUMP DEPOSITION - A method of forming a metal feature on a workpiece with deposition is provided. The method includes providing an under bump metal layer for solder of an electronic device on the workpiece, depositing a substantially pure tin layer directly to the under bump metal layer, and depositing a tin silver alloy layer onto the substantially pure tin layer. | 12-27-2012 |
20130334036 | APPARATUS FOR FLUID PROCESSING A WORKPIECE - A method of fluid processing a semiconductor workpiece, including disposing a workpiece holder with a housing capable of containing a fluid, the workpiece holder retaining the workpiece, providing an agitation system connected to the housing and comprising a member disposed within the housing adjacent the workpiece holder, and agitating the fluid by moving the member substantially parallel to a surface of the workpiece with a non-uniform oscillatory motion, the non-uniform oscillatory motion being a series of substantially continuous geometrically asymmetric oscillations wherein each consecutive oscillation of the series is geometrically asymmetric having at least two substantially continuous opposing strokes wherein reversal positions of each substantially continuous stroke of the substantially continuous asymmetric oscillation are disposed asymmetrically with respect to a center point of each immediately preceding substantially continuous stroke of the oscillation. | 12-19-2013 |