Liu, FL
Bai Liu, Cooper City, FL US
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20100303829 | HIV VPR-SPECIFIC T CELL RECEPTORS - The instant invention provides TCRs having one or more amino acid substitutions that bind to the AL9 epitope of the HIV protein vpr (AIIRILQQL (SEQ ID NO: 1)). | 12-02-2010 |
20120177595 | MULTIMERIC IL-15 SOLUBLE FUSION MOLECULES AND METHODS OF MAKING AND USING SAME - The invention provides soluble fusion protein complexes having at least two soluble fusion proteins. The first fusion protein is a biologically active polypeptide covalently linked to an interleukin-15 (IL-15) polypeptide or a functional fragment thereof. The second fusion protein is a second biologically active polypeptide covalently linked to a soluble interleukin-15 receptor alpha (IL-15Rα) polypeptide or a functional fragment thereof. In the complexes of the invention, one or both of the first and second fusion proteins further includes an immunoglobulin Fc domain or a functional fragment thereof; and the first fusion protein binds to the soluble IL-15Rα domain of the second fusion protein to form a soluble fusion protein complex. The invention further provides methods for making and using the complexes of the invention. | 07-12-2012 |
20140134128 | MULTIMERIC IL-15 SOLUBLE FUSION MOLECULES AND METHODS OF MAKING AND USING SAME - The present invention features compositions and methods featuring ALT-803, a complex of an interleukin-15 (IL-15) superagonist mutant and a dimeric IL-15 receptor α/Fc fusion protein useful for enhancing an immune response against a neoplasia (e.g., multiple myeloma, melanoma, lymphoma) or a viral infection (e.g., human immunodeficiency virus). | 05-15-2014 |
20140205560 | MULTIMERIC IL-15 SOLUBLE FUSION MOLECULES AND METHODS OF MAKING AND USING SAME - The invention provides soluble fusion protein complexes having at least two soluble fusion proteins. The first fusion protein is a biologically active polypeptide covalently linked to an interleukin-15 (IL-15) polypeptide or a functional fragment thereof. The second fusion protein is a second biologically active polypeptide covalently linked to a soluble interleukin-15 receptor alpha (IL-15Rα) polypeptide or a functional fragment thereof. In the complexes of the invention, one or both of the first and second fusion proteins further includes an immunoglobulin Fc domain or a functional fragment thereof; and the first fusion protein binds to the soluble IL-15Rα domain of the second fusion protein to form a soluble fusion protein complex. The invention further provides methods for making and using the complexes of the invention. | 07-24-2014 |
20140242025 | MULTIMERIC IL-15 SOLUBLE FUSION MOLECULES AND METHODS OF MAKING AND USING SAME - The present invention features compositions and methods featuring ALT-803, a complex of an interleukin-15 (IL-15) superagonist mutant and a dimeric IL-15 receptor α/Fc fusion protein useful for enhancing an immune response against a neoplasia (e.g., multiple myeloma, melanoma, lymphoma) or a viral infection (e.g., human immunodeficiency virus). | 08-28-2014 |
20150087059 | HIV VPR-SPECIFIC T-CELL RECEPTORS - The instant invention provides TCRs having one or more amino acid substitutions that bind to the AL9 epitope of the HIV protein vpr (AIIRILQQQL). | 03-26-2015 |
20150374790 | IL-15-BASED MOLECULES AND METHODS OF USE THEREOF - The invention features combination therapies using an IL-15-based superagonist complex and an antibody to effectively treat subjects with cancer and infectious diseases. | 12-31-2015 |
Canhui Liu, Lutz, FL US
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20150237904 | Method of Making Fermented Turtle Shell Powder Mixture - This invention provides a quick and sanitary way to change inedible and almost useless shells of freshwater hard shell turtles into an edible and extremely valuable fermented turtle shell powder mixture with a salutary taste and attractive smell. The novelties taught herein maximize the retention of turtle shell nutrition and minimize any irritation that can be caused from the traditional method of making turtle shell powder. Also, this enhances the digestive absorption of the powder thereby efficiently improving human's health and looks. No negative side effects have been observed to this product. Various steps are provided that enhance the positive benefits of the powder. | 08-27-2015 |
Chang-Chia Liu, Gainesville, FL US
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20080243204 | VARIATIONAL PARAMETER NEUROSTIMULATION PARADIGM FOR TREATMENT OF NEUROLOGIC DISEASE - The present invention concerns a neural stimulation device, and methods for its use, in which one or more stimulation parameters can be automatically and randomly adjusted such that any particular combination of stimulation parameters is not repeated for a given duration of time, thereby limiting habituation to the neural stimulus. | 10-02-2008 |
20110082381 | Time Frequency Transformation Analysis for Detection and Quantification of Epileptiform Activity Load in Generalized Epilepsies - Methods for detecting absence seizures are provided. An electroencephalogram (EEG) recording from a patient can be analyzed using an algorithm. The algorithm can include wavelet transform, in which wavelets can extract an original signal into scales that can be mapped into different pseudofrequencies. The algorithm can also include a sliding variance technique (SVT). | 04-07-2011 |
Chihray Liu, Gainesville, FL US
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20150085072 | AMBIGUITY-FREE OPTICAL TRACKING SYSTEM - An ambiguity-free optical tracking system ( | 03-26-2015 |
20150126796 | PREVENTION OF SETUP ERRORS IN RADIOTHERAPY - A patient safety system (PSS) ( | 05-07-2015 |
20150343239 | QUALITY-CONTROL JIG FOR USE WITH RADIOTHERAPY APPARATUS - A jig for calibrating an image-guided radiotherapy apparatus is disclosed. The jig includes a ball bearing and a three-axis positioner. Once the ball bearing has been moved to the calculated radiation isocenter of the apparatus, other calibration procedures can be performed by directing light onto the jig. | 12-03-2015 |
20150374443 | CRANIAL ALIGNMENT DEVICE FOR USE IN INTRACRANIAL STEREOTACTIC SURGERY - A cranial alignment device for use in intracranial stereotactic radiotherapy includes a nosepiece that is custom shaped to mate with the dorsum and alae of the patient's nose. | 12-31-2015 |
Chunli Liu, Palmetto Bay, FL US
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20100086541 | REGULATION OF AUTOPHAGY PATHWAY PHOSPHORYLATION AND USES THEREOF - The invention relates to polypeptides and proteins known to function in the autophagy pathway that have novel phosphorylation sites. The invention also relates to antibodies specific to these polypeptides and proteins that are phosphorylated or not phosphorylated at novel phosphorylated sites. The invention also relates to methods of producing these antibodies and use of these antibodies in the treatment of diseases related to autophagocytosis. | 04-08-2010 |
20100092458 | REGULATION OF APG8 PHOSPHORYLATION AND USES THEREOF - The invention relates to proteins and peptides of the alpha isoform of light chain 3 (APG8) and antibodies to the APG8 protein, particularly antibodies that specifically bind to the alpha isoform of APG8 when either phosphorylated or not phosphorylated at serine-12 and antibodies that bind to the gamma isoform of APG8 when either phosphorylated or not phosphorylated at serine-9. The invention also relates to methods of producing these antibodies and use of these antibodies in the treatment of diseases related to autophagocytosis. | 04-15-2010 |
20120258550 | REGULATION OF AUTOPHAGY PATHWAY PHOSPHORYLATION AND USES THEREOF - The invention relates to polypeptides and proteins known to function in the autophagy pathway that have novel phosphorylation sites. The invention also relates to antibodies specific to these polypeptides and proteins that are phosphorylated or not phosphorylated at novel phosphorylated sites. The invention also relates to methods of producing these antibodies and use of these antibodies in the treatment of diseases related to autophagocytosis. | 10-11-2012 |
Guoqiang Liu, Miramar, FL US
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20090106738 | METHODS, SYSTEMS, AND COMPUTER PROGRAM PRODUCTS FOR REAL TIME CONFIGURATION AND ANALYSIS OF NETWORK BASED ALGORITHMIC SERVICE OBJECTIVES - A network based algorithmic Service Objective (SO) is evaluated by defining an SO script comprising a plurality of Service Indicators (SIs), each of the SIs comprising an equation including a plurality of operands and at least one operator, instantiating the SO script into an object-oriented representation of the SO, obtaining values for each of the plurality of operands, and computing each of the SI equations using the obtained values. | 04-23-2009 |
Guoqing Liu, Tampa, FL US
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20120093781 | HUMAN MAST CELL LINE AND USES THEREOF - The subject invention pertains to the development of a novel human mast cell line, USF-MC1. USF-MC1 is a mast cell precursor present in human umbilical cord blood (HUCB) that may be sustained in culture in the absence of exogenous cytokines to serve as a convenient experimental model of human mast cell activation. The SCF-independent human mast cell line USF-MC1 responds to IgE-mediated and IgE-independent stimuli in a way comparable to that of LAD2. USF-MC1 cells are useful for investigation of IgE-mediated activation mechanisms of human mast cells, contributing to the development of effective treatments for allergic disorders and other disorders. The subject invention provides a ready source of human mast cells for research, including pharmacological studies for the screening of various agents, and toxicologic, e.g., for the cosmetic and pharmaceutical industries. The mast cells can also be used as biofactories, for the large-scale production of biomolecules. | 04-19-2012 |
Hanzhou Liu, Oviedo, FL US
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20140191596 | HIGH EFFICIENCY PERMANENT MAGNET MACHINE - The present invention is a high efficiency permanent magnet machine capable of maintaining high power density. The machine is operable over a wide range of power output. The improved efficiency is due in part to copper wires with a current density lower than traditional designs and larger permanent magnets coupled with a large air gap. In a certain embodiment wide stator teeth are used to provide additional improved efficiency through significantly reducing magnetic saturation resulting in lower current. The machine also has a much smaller torque angle than that in traditional design at rated load and thus has a higher overload handling capability and improved efficiency. In addition, when the machine is used as a motor, an adaptive phase lag compensation scheme helps the sensorless field oriented control (FOC) scheme to perform more accurately. | 07-10-2014 |
20140340011 | HIGH EFFICIENCY PERMANENT MAGNET MACHINE - The present invention is a high efficiency permanent magnet machine capable of maintaining high power density. The machine is operable over a wide range of power output. The improved efficiency is due in part to copper wires with a current density lower than traditional designs and larger permanent magnets coupled with a large air gap. In a certain embodiment wide stator teeth are used to provide additional improved efficiency through significantly reducing magnetic saturation resulting in lower current. The machine also has a much smaller torque angle than that in traditional design at rated load and thus has a higher overload handling capability and improved efficiency. In addition, when the machine is used as a motor, an adaptive phase lag compensation scheme helps the sensorless field oriented control (FOC) scheme to perform more accurately. | 11-20-2014 |
Hongtan Liu, Miami, FL US
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20100112406 | ULTRASONICALLY ENHANCED FUEL CELL SYSTEMS AND METHODS OF USE - A fuel cell system comprises at least one fuel source (e.g., methanol or methanol solution) In a storage tank, tubes and/or flow channels that provide the fuel to the fuel cells via tubes and/or flow channels, which are used to connect the different fuel cells and/or supply the fuel to all or some of the fuel cells, one or more ultrasonic transducers, which are set inside or are associated with the tubes and/or flow channels through which the fuel (e.g., methanol or methanol solution) is supplied to the fuel cells. The transducers can optionally be integrated with the tubes and/or flow channels of the fuel cell systems. The ultrasonic transducers are able to generate high frequency vibration, and the fuel is able to transmit the high-frequency vibration through the liquid fuel body, to increase the performance of the fuel fed fuel cell system. | 05-06-2010 |
Hongyan Liu, Gainesville, FL US
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20130034532 | NANOZYMES, METHODS OF MAKING NANOZYMES, AND METHODS OF USING NANOZYMES - Embodiments of the present disclosure provides for nanozymes, methods of making nanozymes, methods of using nanozymes, and the like. | 02-07-2013 |
Jeng Hua Liu, Lakeland, FL US
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20100225244 | LED penlight bulb - The invention presents a new design of one-cell and two-cell LED penlight bulbs and it's embedded PCB electronic circuit board structure, specially shaped LED encapsulation and a base to make it physically interchangeable with standard incandescent penlight bulbs. The bulb houses a super bright LED in a specially shaped, spherical molded top. The leads from the LED are soldered on the PC Board that is embedded inside the base. The PC Board power input ports connect to the metal base. The base and the LED molded encapsulation are attached together by means of bonding (thermal, sonic or solvent), friction interference fit or adhesive. The PC Board utilizes an amplifier design which allows the LED to be powered by either one or two 1.5 volt dry cells. The simple bulb design significantly reduces the weight of the entire product, generates much less heat and also dramatically reduces the power consumption of the penlight. | 09-09-2010 |
Jianhua Liu, Orlando, FL US
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20110180140 | SUPRAMOLECULAR STRUCTURES COMPRISING AT LEAST PARTIALLY CONJUGATED POLYMERS ATTACHED TO CARBON NANOTUBES OR GRAPHENES - A composition of matter includes at least one carbon nanotube (CNT) or a graphene type structure having an outer surface, and a plurality of crystalline polymer supramolecular structures that include a conjugated polymer that are non-covalently secured to the outer surface of the CNTs or the graphene type structure. The conjugated polymer can be a conjugated homopolymer or a block copolymer including at least one conjugated block. The supramolecular structures extend outward from the outer surface of the CNTs or graphene type structures. | 07-28-2011 |
20140072704 | METHOD OF FORMING COMPOSITE MATERIALS INCLUDING CONJUGATED MATERIALS ATTACHED TO CARBON NANOTUBES OR GRAPHENES - A method of forming composite materials includes dispersing a conjugated material, a solvent for the conjugated material, and a plurality of carbon nanotubes (CNTs) or graphene including structures having an outer surface to form a dispersion. The solvent is evaporated from the dispersion to yield a CNT or graphene composite including a plurality of crystalline supramolecular structures having the conjugated material non-covalently secured to the outer surface of the CNT or the graphene including structure. The supramolecular structures have an average length which extends outward in a length direction from the outer surface of the CNT or graphene including structure, where the average length is greater than an average width of the supramolecular structures. | 03-13-2014 |
Jianwen Liu, Gainesville, FL US
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20120093772 | VECTORS FOR DELIVERY OF LIGHT SENSITIVE PROTEINS AND METHODS OF USE - Provided herein are compositions and methods for gene and etiology-nonspecific and circuit-specific treatment of diseases, utilizing vectors for delivery of light-sensitive proteins to diseased and normal cells and tissues of interest. | 04-19-2012 |
20150225741 | VECTORS FOR DELIVERY OF LIGHT SENSITIVE PROTEINS AND METHODS OF USE - Provided herein are compositions and methods for gene and etiology-nonspecific and circuit-specific treatment of diseases, utilizing vectors for delivery of light-sensitive proteins to diseased and normal cells and tissues of interest. | 08-13-2015 |
Jilin Liu, Gainesville, FL US
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20150353938 | CODON OPTIMIZED NUCLEIC ACID ENCODING A RETINITIS PIGMENTOSA GTPASE REGULATOR (RPGR) - This invention relates generally to a codon optimized nucleic acid encoding a retinitis pigmentosa GTPase regulator (RPGR) protein. The nucleic acid has enhanced stability during plasmid production relative to a wildtype cDNA encoding the RPGR protein. The invention also relates to expression cassettes, vectors, and host cells comprising the codon optimized nucleic acid. Methods for preparing a recombinant adeno-associated (rAAV) expression vector comprising the codon optimized nucleic acid sequence are also provided. The nucleic acids, expression cassettes, vectors, and host cells provided may be useful in the large scale production of rAAV expression vectors for gene therapy applications. | 12-10-2015 |
John Xianrong Liu, Miami, FL US
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20100069485 | Method for maintaining freshness of fruits and vegetables - A process and a composition to extend the freshness of fruits and vegetables are disclosed. The method comprises treating fresh fruit or vegetable structures with a solution comprising organic acids including N-acetyl cysteine. | 03-18-2010 |
Kaikai Liu, Gainesville, FL US
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20150156637 | APPARATUS, METHOD, AND SOFTWARE SYSTEMS FOR SMARTPHONE-BASED FINE-GRAINED INDOOR LOCALIZATION - Techniques for accurate, low-complexity, scalable indoor localization. Low-complexity anchor nodes generate acoustic beacon signals, which are passively detectable by a mobile device, which may be unmodified smartphones operating in an acoustic frequency range. The acoustic beacon signals are modulated via codes in a boundary band of audio and ultrasound frequencies, imperceptible to humans yet detectable via a voice microphone of an unmodified smartphone. An application on the mobile device passively captures the acoustic beacon signals and determines relative distances to the anchor nodes. Localization and distance update techniques, implemented on the mobile device and/or a remote server, determines and updates in real-time the location of the mobile device. The system may be scalable to support any number of mobile devices. Based on the tracked location, the indoor localization system may provide indoor location-based-services (LBS) to the mobile devices, and transmit to the mobile device information relevant to its location. | 06-04-2015 |
Kechuan Kevin Liu, Weston, FL US
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20090038780 | Pumpless liquid cooling system - A pumpless liquid cooling system for removing heat from heat-generating components or systems comprises a heat absorbing portion or cold plate, a heat dissipating portion or heat exchanger and at least one driving device. The heat absorbing portion and the heat dissipating portion are of unitary construction as a sealed container with working fluid inside. The driving device and the heat dissipating portion is co-axially aligned and attached or fastened together. The heat absorbing portion is configured to have at least one thermal contact surface and a plurality of liquid passage within. The heat dissipating portion is configured to have a heat-dissipating body with plurality of external fins and an internal cylindrical liquid passage communicating with those of the heat absorbing portion and having a running fitting impeller driven by the driving device via magnetic forces to circulate the liquid in the heat transfer loop. Meanwhile the driving device moves the cool air through the fins of the heat dissipating portion to reject the heat absorbed by the heat absorbing portion. | 02-12-2009 |
20110013374 | Integral Spring Clip for Heat Dissipators - An integral spring clip for use with a heat dissipator or heat sink apparatus comprises a securing portion and an attaching portion. The securing portion is configured to flex about a pivot axis to effect an engaged relation to substantially fixedly maintain the electronic component in abutting relation to the heat absorbing surface of a heat dissipater or a heat sink apparatus and secure it in a predefined position. The attaching portion comprises a plurality of solderable elements and is configured to attach a heat dissipator assembly in either vertical or horizontal orientation firmly onto a printed circuit or wiring board in a pre-defined place via soldering techniques. The ramified integral spring clip with a cam bar added on will further facilitate the assembly and disassembly operations. The integral spring clip is a simple unitary design and made of a single length spring wire with whole or selective solder coating. | 01-20-2011 |
20110155360 | Surface mount heat sink apparatus - A surface mountable heat sink apparatus for use with surface mount electronic components comprises a heat dissipating body and a plurality of solderable feet complying with Surface Mounting Technology (SMT). The heat dissipating body and the solderable feet are made of different materials and of unitary construction. The solderable feet project partially beyond one edge of the heat dissipating body. The surface mount heat sink apparatus and surface mount electronic component are touchlessly sandwiched and simultaneously soldered onto the solder drain pads on the printed circuit board. Heat dissipated from the surface mount electronic component is conductively transferred to the heat sink body through the solder drain pad, printed circuit board and solderable feet, and finally rejected to surroundings thereafter. Like all the SMT electronic components, the surface mount heat sink apparatus can be placed onto the printed circuit board manually or automatically by a pick-&-place automation equipment. | 06-30-2011 |
Ko-Chih Liu, Rockledge, FL US
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20100145962 | PROVIDING PROCESSING INSTRUCTIONS FOR UPDATING SCHEMA - A system, method and computer program product are disclosed that enable providing processing instructions for updating schema. In one embodiment, the method includes obtaining an updated schema that includes an updated version of a previous schema; identifying a difference between the updated schema and the previous schema; processing the difference to create processing instructions; and providing the processing instructions for implementation into a logical processor, wherein the logical processor processes data defined using the updated schema. | 06-10-2010 |
Meizhu Liu, Gainesville, FL US
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20120088981 | Matching of Regions of Interest Across Multiple Views - Described herein is a framework for multi-view matching of regions of interest in images. According to one aspect, a processor receives first and second digitized images, as well as at least one CAD finding corresponding to a detected region of interest in the first image. The processor determines at least one candidate location in the second image that matches the CAD finding in the first image. The matching is performed based on local appearance features extracted for the CAD finding and the candidate location. In accordance with another aspect, the processor receives digitized training images representative of at least first and second views of one or more regions of interest. Feature selection is performed based on the training images to select a subset of relevant local appearance features to represent instances in the first and second views. A distance metric is then learned based on the subset of local appearance features. The distance metric may be used to perform matching of the regions of interest. | 04-12-2012 |
Ming Chen Liu, Gainesville, FL US
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20090087868 | Neural Proteins as Biomarkers for Nervous System Injury and Other Neural Disorders - The present invention identifies biomarkers that are diagnostic of nerve cell injury and/or neuronal disorders. Detection of different biomarkers of the invention are also diagnostic of the degree of severity of nerve injury, the cell(s) involved in the injury, and the subcellular localization of the injury. | 04-02-2009 |
20090317805 | Proteolytic Markers as Diagnostic Biomarkers for Cancer, Organ Injury and Muscle Rehabilitation/Exercise Overtraining - The present invention identifies biomarkers that are diagnostic of nerve cell injury, organ injury, and/or neuronal disorders. Detection of different biomarkers of the invention are also diagnostic of the degree of severity of nerve injury, the cell(s) involved in the injury, and the subcellular localization of the injury. | 12-24-2009 |
20100047817 | Synaptotagmin and Collapsin Response Mediator Protein as Biomarkers for Traumatic Brain Injury - Collapsin response mediator proteins (CRMPs) decreased in tissue and increased in biological fluids after neural injury from traumatic brain injury (TBI). Significant decreases of CRMP1, CRMP2, CRMP4 and CRMP5 were accompanied by the appearance of distinct 58 kDa (CRMP-2) or 55 kDa (CRMP-4) breakdown products from proteolytic cleavage by calpain. Synaptotagmin breakdown products were also associated with TBI and could be detected along with intact protein in human cerebral spinal fluid (CSF). Both biomarkers were detected in human biofluid and related to recovery from traumatic brain injury. | 02-25-2010 |
20120196307 | SYNAPTOTAGMIN AND COLLAPSIN RESPONSE MEDIATOR PROTEIN AS BIOMARKERS FOR TRAUMATIC BRAIN INJURY - Collapsin response mediator proteins (CRMPs) decreased in tissue and increased in biological samples after neural injury from traumatic brain injury (TBI). Significant decreases of CRMP1, CRMP2, CRMP4 and CRMP5 were accompanied by the appearance of distinct 58 kDa (CRMP-2) or 55 kDa (CRMP-4) breakdown products from proteolytic cleavage by calpain. Synaptotagmin breakdown products were also associated with TBI and could be detected along with intact protein in human cerebral spinal fluid (biological samples). Both biomarkers were detected in human biofluid and related to recovery from traumatic brain injury. | 08-02-2012 |
Ming Cheng Liu, Alachua, FL US
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20130022982 | MICRO-RNA, AUTOANTIBODY AND PROTEIN MARKERS FOR DIAGNOSIS OF NEURONAL INJURY - Processes and materials are provided for the detection, diagnosis, or determination of the severity of a neurological injury or condition, including traumatic brain injury, multiple-organ injury, stroke, Alzeimer's disease, Pakinson disease and Chronic Traumatic Encephalopathy (CTE). The processes and materials include biomarkers detected or measured in a biological sample such as whole blood, serum, plasma, or CSF. Such biomarkers include Tau and GFAP proteins, their proteolytic breakdown products, brain specific or enriched micro-RNA, and brain specific or enriched protein directed autoantibodies. The processes and materials are operable to detect the presence of absence of acute, subacute or chronic brain injuries and predict outcome for the brain injury. | 01-24-2013 |
Ming-Cheng Liu, Gainesville, FL US
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20100317041 | NEURAL PROTEINS AS BIOMARKERS FOR NERVOUS SYSTEM INJURY AND OTHER NEURAL DISORDERS - The present invention identifies biomarkers that are diagnostic of nerve cell injury and/or neuronal disorders. Detection of different biomarkers of the invention are also diagnostic of the degree of severity of nerve injury, the cell(s) involved in the injury, and the subcellular localization of the injury. | 12-16-2010 |
20110177974 | NEURAL PROTEINS AS BIOMARKERS FOR NERVOUS SYSTEM INJURY AND OTHER NEURAL DISORDERS - The present invention identities biomarkers that are diagnostic of nerve cell injury and/or neuronal disorders. Detection of different biomarkers of the invention are also diagnostic of the degree of severity of nerve injury, the cell(s) involved in the injury, and the subcellular localization of the injury. | 07-21-2011 |
Nen-Chin Liu, Wellington, FL US
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20080297353 | Deactivation for Magnetomechanical Marker Used in Electronic Article Surveillance - A marker for use in a magnetomechanical electronic article surveillance system is described. The EAS marker includes at least one resonator, a housing configured to provide a cavity for vibration of the at least one resonator, a first, magnetized, biasing element configured to provide a biasing magnetic field for the at least one resonator, and a second, non-magnetized, biasing element. | 12-04-2008 |
20100279056 | AMORPHOUS ALLOY COMPOSITION FOR A MAGNETOMECHANICAL RESONATOR AND EAS MARKER CONTAINING SAME - The invention may include a novel composition for and/or processing of an active element for an EAS marker that achieves the same or better performance of existing materials while solving the problem of higher cost. It may include a magnetomechanical active element formed by planar strip of amorphous magnetostrictive alloy having a composition Fe | 11-04-2010 |
20140232544 | ADHESIVE-BONDED ARTICLE PROTECTION TAG - A security system tag. The security system tag includes a housing. The security system tag further includes an electronic article surveillance, EAS, element in which the EAS element is arranged to emit a detectable signal when introduced to an interrogation signal. The security system tag further includes a metal element in which the metal element is adapted to be heated. The security system tag further includes a first reversible adhesive proximate the metal element in which at least a portion of the first reversible adhesive de-bonds when thermally affected by the metal element when the metal element is heated. | 08-21-2014 |
20150356842 | ENHANCED SIGNAL AMPLITUDE IN ACOUSTIC-MAGNETOMECHANICAL EAS MARKER | 12-10-2015 |
Puchun Liu, Miami, FL US
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20140105979 | COMPOSITIONS AND METHODS FOR THE TRANSDERMAL DELIVERY OF METHYLPHENIDATE - Compositions for the transdermal delivery of methylphenidate in a flexible, finite form are described. The compositions comprise a polymer matrix that includes methylphenidate or a pharmaceutically acceptable salt and at least one acrylic polymer that is non-reactive with methylphenidate. Methods using the compositions to achieve transdermal delivery of methylphenidate or for treating Attention Deficit Disorder (ADD) and/or Attention Deficit/Hyperactivity Disorder (ADHD), postural orthostatic tachycardia syndrome, or narcolepsy also are described. | 04-17-2014 |
20140276478 | COMPOSITIONS AND METHODS FOR TRANSDERMAL DELIVERY OF TERTIARY AMINE DRUGS - Described are transdermal drug delivery systems for the transdermal administration of tertiary amine drugs, such as rivastigmine, fentanyl or rotigotine, comprising a polymer matrix comprising a free base form of the drug and at least one carboxyl group-containing compound. In some embodiments, the systems include a rate-controlling membrane and a skin-contacting face adhesive apart from the polymer matrix. | 09-18-2014 |
20140276479 | TRANSDERMAL DRUG DELIVERY SYSTEM WITH OVERLAY - Transdermal drug delivery systems comprising a drug-containing layer, a backing layer, and an occlusive overlay layer extending beyond the perimeter of the backing layer by 3 to 6 mm in all directions are described. The systems achieve increased drug delivery over an extended time period. | 09-18-2014 |
20140276483 | TRANSDERMAL METHYLPHENIDATE COMPOSITIONS WITH ACRYLIC BLOCK COPOLYMERS - Described herein are transdermal compositions comprising methylphenidate in a polymer matrix comprising a non-reactive random acrylic polymer and an acrylic block copolymer. Method of making such compositions, and therapeutic methods using them also are disclosed. | 09-18-2014 |
20160030362 | SILICONE-CONTAINING ACRYLIC POLYMERS FOR TRANSDERMAL DRUG DELIVERY COMPOSITIONS - Described herein are silicone-containing acrylic polymers useful, for example, in transdermal drug delivery compositions, to methods of making and using them, to transdermal drug delivery compositions comprising them, and to methods of making and using such transdermal drug delivery compositions. The polymers are particular suitable for formulating amine drugs, such as amphetamine, methylphenidate, rivastigmine, paroxetine and clonidine. | 02-04-2016 |
Richard Y. Liu, Lutz, FL US
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20090258927 | Method for the Modulation of Function of Transcription Factors - There is provided a method of modulating the function of transcription factor by administering an effective amount of an oligonucleotide containing optimal nucleotide binding sites for the transcription factor. A therapeutic agent having an effective amount of an oligonucleotide for modulating function of transcription factors and a pharmaceutically acceptable carrier is also provided. Also provided is a treatment of patients having illnesses in which the activation of transcription factors play a role by administering to a patient an effective amount of an oligonucleotide which competitively binds the related transcription factor. | 10-15-2009 |
Shih-Xiang Liu, Jacksonville, FL US
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20150180257 | BATTERY ELECTRONICS AND CONTROL SYSTEM - The invention is directed to a system for controlling battery current. In some embodiments, the system comprises a first lithium-ion (Li-ion) battery, the first battery having a first state-of-charge (SOC) and comprising a first battery controller and a first battery charger; and a second Li-ion battery in series with the first battery, the second battery having a second SOC and comprising a second battery controller and a second battery charger. In some embodiments, at least one of the first battery controller or the second battery controller controls a charge current flowing through at least one of the first battery and the second battery, wherein control of the charge current is transferred from the first battery to the second battery based at least partially on whether an overhead voltage is present across the first battery charger or the second battery charger. | 06-25-2015 |
Xiaohu Liu, Tallahassee, FL US
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20140063874 | HIGH-FREQUENCY-LINK POWER-CONVERSION SYSTEM HAVING DIRECT DOUBLE-FREQUENCY RIPPLE CURRENT CONTROL AND METHOD OF USE - A direct double-frequency ripple current control in a two-stage high-frequency-link (HFL) based fuel cell converter that can achieve low-frequency ripple free input current without using large electrolytic capacitors is provided. To eliminate the double-frequency ripple current disturbance introduced by the single-phase inverter load, a proportional-resonant (PR) controller is developed to achieve an extra high control gain at designed resonant frequency. This high gain can be viewed as the virtual high impedance for blocking the double-frequency ripple energy propagation from inverter load to fuel cell stack. More particularly, the proposed control system can realize the utilization of all capacitive ripple energy sources in the system by regulating all the capacitors to have large voltage swing and the voltage swing is synchronized to keep real-time balancing of the transformer primary-side and secondary-side voltages. As a result, the zero-voltage-switching (ZVS) operation for all switching devices in the dc-dc stage can be guaranteed. | 03-06-2014 |
Xiaohu Liu, Tallahasee, FL US
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20100109616 | System and method for reactive power compensation and flicker management - A Thyristor Switched Capacitor (TSC) system connected to three sets of diodes and thyristors connected in parallel with the diodes being in an anti-parallel configuration, three capacitors connected in series with the diodes and thyristors, and three surge current controlling reactors that control the transient time to improve power quality in the grid. | 05-06-2010 |
Xinxin Liu, Gainesville, FL US
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20140204759 | Load Balanced Routing for Low Power and Lossy Networks - A node includes a receiver for receiving a first packet from a first node at a first time and a second packet from a second node at a second time, a processor for determining the first time and the second time and for comparing the first time with the second time to produce a ratio of workloads of the first node and the second node, and a transmitter for transmitting packets to the first and the second nodes based on the ratio. | 07-24-2014 |
Xiong Liu, Oviedo, FL US
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20100285989 | DETECTION OF ANALTYES USING METAL NANOPARTICLE PROBES AND DYNAMIC LIGHT SCATTERING - Disclosed herein are systems and methods for detecting Chemical Species, Biomolecules and Biotargets (Analytes) using receptor functionalized metal nanoparticles and Dynamic Light Scattering. | 11-11-2010 |
20120058548 | DETECTION OF BIOTARGETS USING BIORECEPTOR FUNCTIONALIZED NANOPARTICLES - A system for determining a presence of biomolecule targets includes a vessel holding a sample solution suspected of containing the biomolecule targets and a plurality of probes including bioreceptor functionalized metal nanoparticles including a plurality of metal atoms. The biomolecule targets when present in the sample solution bind to the plurality of probes. A separation device is for separating the plurality of probes into a first group of probes having the biomolecule targets bound thereto and a second group of probes not having the biomolecule targets bound thereto. A reagent is introduced via a port for breaking down the metal nanoparticles in the first group or second group of probes, wherein at least one signal moiety solution is formed. A device measures a parameter of the signal moiety solution. | 03-08-2012 |
Yi-Fan Liu, Orlando, FL US
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20140022494 | LIQUID CRYSTAL DISPLAY - A liquid crystal display is provided, which includes a first substrate, a plurality of pixels, a second substrate, a plurality of floating electrodes, and a liquid crystal layer. The pixels are arranged in an array on the first substrate, and each of the pixels includes a first electrode and a second electrode, wherein a space is maintained between the first electrode and the second electrode. The floating electrodes are disposed on the second substrate and above the spaces. The liquid crystal layer is located between the first substrate and the second substrate, wherein the liquid crystal layer is optically isotropic when the first electrode and the second electrode have no voltage difference; and the liquid crystal layer is optically anisotropic when the first electrode and the second electrode have a voltage difference therebetween. | 01-23-2014 |
20140184991 | LIQUID CRYSTAL DISPLAY - A liquid crystal display includes an upper substrate, a lower substrate, a liquid crystal layer disposed between the upper and lower substrates and including liquid crystal molecules with optical isotropicity, a first polarizer disposed on a surface of the upper substrate, having a first polarization direction, a second polarizer disposed on a surface of the lower substrate, having a second polarization direction, and at least one pixel region defined on the lower substrate. The pixel region includes at least one pixel electrode disposed on the lower substrate, the pixel electrode extending along a first direction in the pixel region and a majority portion of an edge of the pixel electrode substantially being parallel to at least one of the first polarization direction and the second polarization direction. | 07-03-2014 |
20140300847 | DISPLAY APPARATUS - A display apparatus including a display panel, a first polarizer and a second polarizer is provided. The display panel includes a pixel array substrate, an opposite substrate and a display medium. The pixel array substrate includes a plurality of pixel units. Each pixel unit includes a first electrode and a second electrode. The first electrode and the second electrode are alternately arranged and a lateral electric field is existed between the first electrode and the second electrode. The opposite substrate is disposed opposite to the pixel array substrate. The display medium is disposed between the pixel array substrate and the opposite substrate. The first polarizer is disposed on the pixel array substrate. The second polarizer is disposed on the opposite substrate. An included angle between an optical axis of the first polarizer and an optical axis of the second polarizer is 90°±θ, and θ is 1° to 9°. | 10-09-2014 |
Yizhe Liu, St. Petersburg, FL US
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20160072404 | SYNCHRONOUS BUCK INVERTER - A power inverter, such as a synchronous buck power inverter, that is configured with a high frequency switching control having a (PWM) controller and sensing circuit. Controller provides a low frequency oscillating wave to effect switching control on a synchronous-buck circuit portion that includes a plurality of switches to invert every half cycle of the frequency provided by controller. The inverting process thus creates a positive and negative transition of the oscillating wave signal. A low frequency switching stage includes a further plurality of switches configured to operate as zero voltage switching (ZVS) and zero current switching (ZCS) drives Charge on an output capacitor is discharged to zero on every zero crossing of low frequency switching stage and advantageously discharges energy every half cycle. During this discharge of energy, the zero crossing distortion in the low frequency sine wave is greatly reduced. | 03-10-2016 |
20160072437 | WEIN BRIDGE OSCILLATOR - An oscillator circuit that includes a Wien bridge oscillator circuit, a full-wave rectifier circuit, coupled to an output of the Wien bridge oscillator circuit, an integrator circuit, coupled to an output of the full-wave rectifier circuit, and a multiplier circuit. The multiplier circuit may include a first input coupled to the output of the Wien bridge oscillator circuit, and a second input, coupled to an output of the integrator, wherein the multiple signals are configured to provide dynamic gain control to the Wien bridge oscillator circuit. | 03-10-2016 |
Zhao-Jun Liu, Miami, FL US
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20120058086 | COMPOSITIONS, KITS, AND METHODS FOR PROMOTING ISCHEMIC AND DIABETIC WOUND HEALING - Compositions, kits and methods for promoting diabetic wound healing are based on the discovery that SDF-1α specifically upregulates expression of E-selectin in mature endothelial cells (EC), leading to an increase in EC-endothelial progenitor cell (EPC) adhesion and EPC homing. Methods for promoting healing of a wound in a diabetic subject include providing a therapeutically effective amount of a composition including E-selectin protein or a nucleic acid encoding E-selectin protein, and optionally, an agent that specifically upregulates E-selectin expression (e.g., SDF-1α). The methods can also include administering hyperbaric oxygen treatment to the subject. Administering the composition to the subject results in migration of bone marrow-derived progenitor cells to the wound, accelerated wound healing, and upregulation of E-selectin expression in the subject. | 03-08-2012 |
Zhiwei Liu, Orlando, FL US
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20090212323 | SILICON-CONTROLLED RECTIFIER (SCR) DEVICE FOR HIGH-VOLTAGE ELECTROSTATIC DISCHARGE (ESD) APPLICATIONS - A silicon-controlled rectifier (SCR) device having a high holding voltage includes a PNP transistor and an NPN transistor, each transistor having both p-type and n-type dopant regions in their respective emitter areas. The device is particularly suited to high voltage applications, as the high holding voltage provides a device which is more resistant to latchup subsequent to an electrostatic discharge event compared to devices having a low holding voltage. | 08-27-2009 |