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Liu, Cambridge
Ce Liu, Cambridge, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20100054694 | COMBINED VISUAL AND AUDITORY PROCESSING - A computer-implemented method includes segmenting a plurality of video frames of a sequence of video frames into a first portion that includes a selected visual object represented in the video frame and a second portion that includes a background represented in the video frame. The selected visual object is selected by using a selection envelope. | 03-04-2010 |
David V. Liu, Cambridge, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20110091412 | MUTANT INTERLEUKIN-2 (IL-2) POLYPEPTIDES - The present invention relates to mutant IL-2 polypeptides that act as receptor antagonists. The mutant IL-2 polypeptides bind CD 25 but do not activate the IL-2 receptor. Also provided are methods of using the mutant IL-2 polypeptides, for example, to treat a patient who has cancer or a viral infection. The mutant polypeptides can also be used in various delivery systems. | 04-21-2011 |
Donglei Liu, Cambridge, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20100168082 | Heterobicyclic Carboxamides as inhibitors for kinases - The invention relates to novel organic compounds of formula (I) | 07-01-2010 |
Haiqun Liu, Cambridge GB
| Patent application number | Description | Published |
|---|---|---|
| 20090297524 | Compositions monovalent for CD40L binding and methods of use - The invention relates to antibody polypeptides that monovalently bind CD40L. Antibody polypeptides that are monovalent for binding of CD40L can inhibit CD40L activity while avoiding potential undesirable effects that can occur with antibodies capable of divalent or multivalent binding of CD40L. In one aspect, a monovalent anti-CD40L antibody polypeptide consists of or comprises a single immunoglobulin variable domain that specifically binds and antagonizes the activity of CD40L, preferably without substantially agonizing CD40 and/or CD40L activity. In another aspect, the monovalent anti-CD40L antibody polypeptide is a human antibody polypeptide. The invention further encompasses methods of antagonizing CD40/CD40L interactions in an individual and methods of treating diseases or disorders involving CD40/CD40L interactions, the methods involving administering a monovalent anti-CD40L antibody polypeptide to the individual. | 12-03-2009 |
| 20100092482 | Compositions monovalent for CD40L binding and methods of use - The invention relates to antibody polypeptides that monovalently bind CD40L. Antibody polypeptides that are monovalent for binding of CD40L can inhibit CD40L activity while avoiding potential undesirable effects that can occur with antibodies capable of divalent or multivalent binding of DC40L. in one aspect, a monovalent anti-CD40L antibody polypeptide consists of or comprises a single immunoglobulin variable domain that specifically binds and antagonizes the activity of DC40L, preferably without substantially agonizing CD40 activity. In another aspect, the monovalent anti-CD40L antibody polypeptide is a human antibody polypeptide. The invention further encompasses methods of antagonizing CD40/CD40L interactions in an individual and methods of treating diseases or disorders involving CD40/DC40L interactions, the methods involving administering a monovalent anti-CD40L antibody polypeptide to the individual. | 04-15-2010 |
| 20100092483 | Compositions monovalent for CD40L binding and methods of use - The invention relates to antibody polypeptides that monovalently bind CD40L. Antibody polypeptides that are monovalent for binding of CD40L can inhibit CD40L activity while avoiding potential undesirable effects that can occur with antibodies capable of divalent or multivalent binding of DC40L. in one aspect, a monovalent anti-CD40L antibody polypeptide consists of or comprises a single immunoglobulin variable domain that specifically binds and antagonizes the activity of DC40L, preferably without substantially agonizing CD40 activity. In another aspect, the monovalent anti-CD40L antibody polypeptide is a human antibody polypeptide. The invention further encompasses methods of antagonizing CD40/CD40L interactions in an individual and methods of treating diseases or disorders involving CD40/DC40L interactions, the methods involving administering a monovalent anti-CD40L antibody polypeptide to the individual. | 04-15-2010 |
Jifeng Liu, Cambridge, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20080199123 | ULTRAFAST GE/SI RESONATOR-BASED MODULATORS FOR OPTICAL DATA COMMUNICATIONS IN SILICON PHOTONICS - An optical modulator structure includes at least two waveguide structures for inputting and outputting an optical signal. At least one ring resonator structure provides coupling between the at least two waveguide structures. The at least one ring resonator structure includes Ge or SiGe. | 08-21-2008 |
| 20100307579 | Pseudo-Periodic Structure for Use in Thin Film Solar Cells - A method of manufacturing a photovoltaic cell includes providing an active absorption layer, forming a pseudo-periodic grating adjacent to the active absorption layer, and forming a reflector adjacent to the pseudo-periodic grating. A photovoltaic cell includes an active absorption layer, a pseudo-periodic grating adjacent to the active absorption layer, and a reflector adjacent to the pseudo-periodic grating. | 12-09-2010 |
Jingjing Liu, Cambridge, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20090292685 | VIDEO SEARCH RE-RANKING VIA MULTI-GRAPH PROPAGATION - A video search re-ranking via multi-graph propagation technique employing multimodal fusion in video search is presented. It employs not only textual and visual features, but also semantic and conceptual similarity between video shots to rank or re-rank the search results received in response to a text-based search query. In one embodiment, the technique employs an object-sensitive approach to query analysis to improve the baseline result of text-based video search. The technique then employs a graph-based approach to text-based search result ranking or re-ranking. To better exploit the underlying relationship between video shots, the re-ranking scheme simultaneously leverages textual relevancy, semantic concept relevancy, and low-level-feature-based visual similarity. The technique constructs a set of graphs with the video shots as vertices, and the conceptual and visual similarity between video shots as hyperlinks. A modified topic-sensitive PageRank algorithm is then applied to these graphs to determine the overall relevancy ranking. | 11-26-2009 |
Mei Liu, Cambridge, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20090155786 | COMPOSITIONS AND METHODS FOR DETECTING MARKERS OF CANCER - Disclosed herein are compositions and methods for detecting one or more markers indicative of cancer. In one instance the marker is one or more methylated genes, such as SFRPs. In another instance the marker is an altered protein, such as p53. | 06-18-2009 |
Shan Liu, Cambridge, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20090003457 | Inverse Tone Mapping for Bit-Depth Scalable Image Coding - A method performs inverse tone mapping of an image in a decoder. For each block of each color channel of the image the following steps are performed. A scaling factor is determined for a current block of the image by adding a predicted scaling factor for the current block to a difference between the predicted scaling factor and the scaling factor of an adjacent block. An offset value for the current block is determined by adding a predicted offset for the current block to a difference between the predicted offset value and the offset value of the adjacent block. The scaling factor and the offset value are applied to pixel intensity values of the current block to produce a mapped block in which a bit-depth of the mapped block is greater than the bit-depth of the current block. | 01-01-2009 |
| 20090003718 | Inverse Tone Mapping for Bit-Depth Scalable Image Coding Adapted to Variable Block Sizes - A method performs inverse tone mapping of an image in a decoder. For each block of each color channel of the image a scaling factor is determined by adding a predicted scaling factor for the current block to a difference between the predicted scaling factor and the scaling factor of an adjacent block. An offset value for the current block is determined by adding a predicted offset for the current block to a difference between the predicted offset value and the offset value of the adjacent block. The scaling factor and the offset value are applied to pixel intensity values of the current block to produce a mapped block. The inverse tone mapping can also be applied to blocks of different sizes. | 01-01-2009 |
| 20090267825 | Method and Apparatus for Compressing SAR Signals - A method compresses synthetic aperture radar (SAR) data by sampling the SAR data into blocks and transforming each block to a corresponding block of transform coefficients. Each block of transform coefficient is quantized according to a quantization parameter to obtain a corresponding block of quantized transform coefficients, which are demultiplexed into sets of blocks of quantized transform coefficients. The quantized transform coefficients in the blocks in each set are arithmetically encoding in parallel according to a probability model to produce an intermediate bitstream for each set of blocks. The encoding of the quantized transform coefficients of one block is independent of the quantized transform coefficients of a successive block. The intermediate of bitstreams are then multiplexed to a compressed bitstream, which can be transmitted, or stored, for subsequent decoding to construct an SAR image. | 10-29-2009 |
Sijia Liu, Cambridge, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20090217206 | MODELESS INTERACTION WITH GUI WIDGET APPLICATIONS - A user displayed interactive GUI widget (icon) provides two or more regions. A first region provides widget manipulation function for editing the widget, editing including moving or sizing functions. A second region provides widget interaction function for user interaction with the widget including interaction lists or interaction graphics. The regions may comprise one or more icon border regions and one or more icon internal regions. | 08-27-2009 |
Tieming Liu, Cambridge, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20080235160 | METHOD AND APPARATUS FOR JOINT PRICING AND RESOURCE ALLOCATION UNDER SERVICE-LEVEL AGREEMENT - There are provided an apparatus, a method, and a computer program product for joint determination of price and resource allocation. The apparatus includes a price and resource allocation determination device for jointly determining a price and a resource allocation for a given item or service offered for use or sale by a given e-retailer to optimize a pre-specified objective for the given e-retailer. | 09-25-2008 |
Wenhao Liu, Cambridge, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20110037029 | Copolymer-associated nanomaterial - A nanomaterial can include an outer layer including a ligand. The ligand can include a first monomer unit including a first moiety having affinity for a surface of the nanocrystal, a second monomer unit including a second moiety having a high water solubility, and a third monomer unit including a third moiety having a selectively reactive functional group or a selectively binding functional group. The ligand can be a random copolymer. | 02-17-2011 |
| 20110059467 | CONTROLLED MODIFICATION OF SEMICONDUCTOR NANOCRYSTALS - A controlled valency semiconductor nanocrystal can have a desired number of compounds associated with it. The semiconductor nanocrystal can have exactly one compound associated with it, and the compound can have exactly one binding site for an affinity target. The semiconductor nanocrystal can be used to image single copies of cell-surface proteins. | 03-10-2011 |
| 20110129420 | MATERIALS AND METHODS FOR BIOLOGICAL IMAGING - Water soluble InAs(ZnCdS) semiconductor nanocrystals with bright and stable emission in the near infrared (NIR) wavelength range have been prepared. The NIR semiconductor nanocrystals can be functionalized to enable imaging of specific cellular proteins. In addition, the utility of the NIR region for in vivo biological imaging is clearly demonstrated by the superior ability of InAs(ZnCdS) semiconductor nanocrystals to image tumor vasculature. | 06-02-2011 |
Xinbing Liu, Cambridge, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20080273836 | ULTRAFAST LASER MACHINING SYSTEM AND METHOD FOR FORMING DIFFRACTIVE STRUCTURES IN OPTICAL FIBERS - An ultrafast laser machining system and method to form diffractive structures in optical fibers. The fiber is mounted with its longitudinal axis perpendicular to the beam path of the laser pulses. A region of the fiber is illuminated and then imaged with two cameras. These cameras are aligned substantially orthogonally. A position of the beam spot is determined. The beam spot is aligned to a starting position within the region. This position is within a portion of the fiber to be machined for which the beam path passes through the greatest length of material. The beam spot is scanned along a path designed to pass the beam spot through all of the portion to be machined such that the beam path does not pass through previously machined material. The laser pulses, which have a duration of less than about 1 ns, are generated as the beam spot is scanned. | 11-06-2008 |
Yanyan Liu, Cambridge, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20090298191 | Lateral Flow and Flow-through Bioassay Devices Based On Patterned Porous Media, Methods of Making Same, and Methods of Using Same - Embodiments of the invention provide lateral flow and flow-through bioassay devices based on patterned porous media, methods of making same, and methods of using same. Under one aspect, an assay device includes a porous, hydrophilic medium; a fluid impervious barrier comprising polymerized photoresist, the barrier substantially permeating the thickness of the porous, hydrophilic medium and defining a boundary of an assay region within the porous, hydrophilic medium; and an assay reagent in the assay region. | 12-03-2009 |