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Littrup
Peter Littrup, Bloomfield Hills, MI US
| Patent application number | Description | Published |
|---|---|---|
| 20100168725 | ISOTHERM-BASED TISSUE ABLATION CONTROL SYSTEM - A system and method for use with at least one cryoprobe for the treatment of biological tissue controls the energy applied to the tissue. The invention receives live procedure data such as temperature information from locations along the pathway of the cryogenic liquids, and calculates a procedure signature or profile based on the procedure data. In one embodiment, volumetric isotherms are calculated. The procedure signature is compared to a planning signature based on previously acquired image data and estimates of the thermal gradients from models. The system and method are further configured to automatically regulate the application of power based on analysis of the planning data to the procedure data. | 07-01-2010 |
| 20100280507 | CRYOABLATION SYSTEM HAVING DOCKING STATION FOR CHARGING CRYOGEN CONTAINERS AND RELATED METHOD - A cryoablation system includes thermally insulated containers for holding liquid refrigerant. The containers are placed in a docking station that charges the containers with a liquid refrigerant at a cryogenic temperature suitable for carrying out a surgical procedure. The charged containers are detachably connectable with an inlet line of a cryoablation probe. When the cryoprobe is activated, the chilled liquid refrigerant is transported from a delivery container, through the cryoprobe, and to a recovery container. The recovery container is preferably identical in design to the delivery container. The refilled recovery container is then placed in the docking station to charge. In another embodiment, a cartridge includes a delivery container and recovery container combined as a single unit. Methods are also described. | 11-04-2010 |
Peter J. Littrup, Bloomfield Hills, MI US
| Patent application number | Description | Published |
|---|---|---|
| 20080275344 | Method and Apparatus for Categorizing Breast Density and Assessing Cancer Risk Utilizing Acoustic Parameters - A method for categorizing whole-breast density is disclosed. The method includes the steps of exposing breast tissue to an acoustic signal; measuring a distribution of an acoustic parameter by analyzing the acoustic signal; and obtaining a measure of whole-breast density from said measuring step. An apparatus is also disclosed. | 11-06-2008 |
| 20090113903 | Cooling methods and systems using supercritical fluids - The methods and systems using supercritical fluids for cooling of objects with high thermal emissions are disclosed. The unique thermodynamic properties of supercritical fluids combined with microchannel cooling technology allow effective absorption of the waste heat and exclude “vapor lock”, “boiling crisis”, and other deficiencies of conventional two-phase liquid cooling. | 05-07-2009 |
| 20090270851 | Method and System for Cryoablation Treatment - A system and a method for its use are provided to cool a cryotip at the distal end of a probe for a cryosurgical procedure. In particular, the cryotip is cooled by a liquid refrigerant to cryogenic temperatures in order to perform a cryosurgical procedure on biological tissue. The system is closed-loop, and during transit of the liquid refrigerant through the entire system, the liquid refrigerant always remains in a liquid state at a relatively low pressure. | 10-29-2009 |
| 20110040297 | FLEXIBLE MULTI-TUBULAR CRYOPROBE - A flexible multi-tubular cryoprobe, including a housing for receiving an inlet flow of near critical cryogenic fluid from a fluid source and for discharging an outlet flow of the cryogenic fluid. A plurality of fluid transfer tubes are securely attached to the housing. This includes a set of inlet fluid transfer tubes for receiving the inlet flow from the housing; and, a set of outlet fluid transfer tubes for discharging the outlet flow to the housing. Each of the fluid transfer tubes is formed of material that maintains flexibility in a full range of temperatures from −200° C. to ambient temperature. Each fluid transfer tube has an inside diameter in a range of between about 0.10 mm and 1.0 mm and a wall thickness in a range of between about 0.01 mm and 0.30 mm. An end cap is positioned at the ends of the plurality of fluid transfer tubes to provide fluid transfer from the inlet fluid transfer tubes to the outlet fluid transfer tubes. | 02-17-2011 |
| 20110162390 | METHODS AND SYSTEMS FOR CRYOGENIC COOLING - Methods and systems are provided for cooling an object with a cryogen having a critical point defined by a critical-point pressure and a critical-point temperature. A pressure of the cryogen is raised above a pressure value determined to provide the cryogen at a reduced molar volume that prevents vapor lock. Thereafter, the cryogen is placed in thermal communication with the object to increase a temperature of the cryogen along a thermodynamic path that maintains the pressure greater than the critical-point pressure for a duration that the cryogen and object are in thermal communication. | 07-07-2011 |
Peter J. Littrup, Detroit, MI US
| Patent application number | Description | Published |
|---|---|---|
| 20110040298 | Method and System for Cryoablating Fibroadenomas - A cryosurgical system adapted for treatment of fibroadenomas within the breast of a patient. The system includes cryoprobes and a control system which operates the cryoprobes to accomplish freezing in two stages, including a high power freeze and a low power freeze. | 02-17-2011 |
Peter John Littrup, Bloomfield Hills, MI US
| Patent application number | Description | Published |
|---|---|---|
| 20110201928 | METHOD OF CHARACTERIZING THE PATHOLOGICAL RESPONSE OF TISSUE TO A TREATMENT PLAN - A method of characterizing the pathological response of tissue to a treatment plan, including: obtaining a set of sequential morphology renderings of the tissue, wherein each rendering corresponds to a particular point in time during the treatment plan; generating a set of representative values of a biomechanical property of the tissue for the set of renderings, wherein each representative value is based on a corresponding rendering; determining a trend of the biomechanical property based on the set of representative values; and predicting response of the tissue to the treatment plan based on the trend of the biomechanical property. | 08-18-2011 |
| 20110201932 | METHOD OF CHARACTERIZING TISSUE OF A PATIENT - A method for characterizing tissue of a patient, including receiving acoustic data derived from the interaction between the tissue and the acoustic waves irradiating the tissue; generating a morphology rendering of the tissue from the acoustic data, in which the rendering represents at least one biomechanical property of the tissue; determining a prognostic parameter for a region of interest in the rendering, in which the prognostic parameter incorporates the biomechanical property; and analyzing the prognostic parameter to characterize the region of interest. In some embodiment, the method further includes introducing a contrast agent into the tissue; generating a set of enhanced morphology renderings of the tissue after introducing the contrast agent; determining an enhanced prognostic parameter from the enhanced morphology renderings; and analyzing the enhanced prognostic parameter. | 08-18-2011 |