Patent application number | Description | Published |
20090171252 | THERAPY HEAD FOR USE WITH AN ULTRASOUND SYSTEM - Therapy heads and related medical systems having an actuation assembly for controlling the position/orientation of a directional energy applicator in at least two planes are disclosed. A therapy head includes an enclosure, a partition separating a lower compartment from an upper compartment, an aperture in the partition, a control arm extending through the aperture, an actuation assembly positioned within the upper compartment, and a directional energy applicator positioned in the lower compartment for transmitting energy through a window. The control arm includes an upper end disposed within the upper compartment and a lower end disposed within the lower compartment. The actuation assembly is coupled with the upper end of the control arm such that the control arm is movable by the actuation assembly in at least two planes. The directional energy applicator is coupled with the lower end of the control arm. | 07-02-2009 |
20100241034 | ANALYSIS OF REAL TIME BACKSCATTER DATA FOR FAULT SIGNAL GENERATION IN A MEDICAL HIFU DEVICE - A method and system for checking functionality of an ultrasound therapy head. The waveform profile for typical ultrasound reflections for a functional therapy head are stored, and before use of a therapy head, an ultrasound energy burst ( | 09-23-2010 |
20100249669 | ULTRASONIC TREATMENT OF ADIPOSE TISSUE AT MULTIPLE DEPTHS - Methods and apparatus ( | 09-30-2010 |
20130096436 | INDUCTIVE TUNING SYSTEM FOR ULTRASOUND TRANSDUCER - Medical devices are disclosed that include a tunable ultrasonic transducer assembly, as well as related assemblies and methods. A medical device includes a transducer controller, a transducer having an input side connected with the ultrasound transducer controller via an input electrical conductor, and a tuning assembly that is electrically connected between the input electrical conductor and the ground potential. The tuning assembly is adjustable to provide a selected inductance from a number of different inductance values. The tuning assembly includes a multi-position switch and a plurality of tuning inductors. The switch is operable to select combinations of tuning inductors, thereby providing a selected inductance value between the input electrical connector and the ground potential so as inductively tune the medical device. | 04-18-2013 |
20140024975 | HIFU COMPONENTS WITH INTEGRATED CALIBRATION PARAMETERS - Devices, systems, and methods for increasing the accuracy of ultrasound power delivered to and received from a patient by an HIFU system having exchangeable components. The system components include one or more memory devices in which calibration parameters for the component are stored, such as when the component is manufactured. During operation of the system, the calibration parameter data is received from the memory and used by the system to adjust the output power of one or more ultrasound sources and/or received signal levels based on the received calibration parameters. The calibration parameters may include data relating to impedance, sensitivity, transfer functions, linearity, or other data that could affect the power delivered to a patient by the component. | 01-23-2014 |
Patent application number | Description | Published |
20090275835 | MODULAR APPARATUS FOR DIAGNOSTIC ULTRASOUND - A modular diagnostic ultrasound apparatus is provided comprising a core unit, system electronics and an I/O port. The core unit comprises a housing and a system electronics package within the housing. The system electronics has one or more concatenated filters, including a front end transmit/receive circuit, a processor, a back end circuit for scan conversion, a system clock and a programmable system memory device. There is at least one I/O port connected to the front end and the back end of the system electronics package and extending through the core unit housing wherein all system data processing information is transmitted or received through the I/O port. | 11-05-2009 |
20100274131 | Balance Body Ultrasound System - The present invention relates to a hand held ultrasound system having a balance body, a transducer assembly connected to said balance body via a communication means and a plurality of control elements arranged in an ergonomic fashion on said balance body, such that a user may hold said system and operate at least one of said control elements with the same hand. In particular a medical ultrasound system comprising a balance body incorporating system electronics, a power supply and a user interface wherein the user interface comprises a D-controller and a touch screen and a transducer assembly attached to the balanced body by a cable. The present invention relates to a hand held ultrasound system having a balance body, a transducer assembly connected to said balance body via a communication means and a plurality of control elements arranged in an ergonomic fashion on said balance body, such that a user may hold said system and operate at least one of said control elements with the same hand. In particular a medical ultrasound system comprising a balance body incorporating system electronics, a power supply and a user interface wherein the user interface comprises a D-controller and a touch screen and a transducer assembly attached to the balanced body by a cable. | 10-28-2010 |
20110077556 | CARTRIDGE FOR USE WITH AN ULTRASOUND THERAPY HEAD - A medical ultrasound system. A base unit is included having system electronics, a user interface and ultrasound control electronics. An ultrasound therapy head is in electronic communication with the base unit. The therapy head includes a replaceable, sealed transducer cartridge with a coupling fluid therein. A cooling system is provided for cooling the coupling fluid. A plurality of guide indicators are positioned around the therapy head to align with crossed lines on a patient so as to properly align the therapy head prior to use. The therapy head can provide variable treatments to an area while the therapy head is in contact with a patient. | 03-31-2011 |
20110077557 | MEDICAL ULTRASOUND DEVICE WITH LIQUID DISPENSING DEVICE COUPLED TO A THERAPY HEAD - A medical ultrasound system. A base unit is included having system electronics, a user interface and ultrasound control electronics. An ultrasound therapy head is in electronic communication with the base unit. The therapy head includes a replaceable, sealed transducer cartridge with a coupling fluid therein. A cooling system is provided for cooling the coupling fluid. A plurality of guide indicators are positioned around the therapy head to align with crossed lines on a patient so as to properly align the therapy head prior to use. The therapy head can provide variable treatments to an area while the therapy head is in contact with a patient. | 03-31-2011 |
20120195161 | SYSTEMS AND METHODS FOR ULTRASOUND BEAM FORMING DATA CONTROL - Disclosed are systems and methods which efficiently control storage of and/or access to data which includes repetitive data or data which is used by different modes, processes, etcetera. Embodiments provide control for storage of and/or access to large amounts of data used in ultrasound system beam forming for image generation using a hierarchy of sequencers for controlling storage of and/or access to data. A frame sequencer may provide control at a frame level while an address sequencer is implemented to provide control at a data access level. | 08-02-2012 |
20120289829 | BALANCE BODY ULTRASOUND SYSTEM - A hand held ultrasound system includes a balance body incorporating system electronics and a transducer assembly connected to the balance body. The hand held ultrasound system also includes control elements that are arranged in an ergonomic fashion on the balance body so that a user can hold the system and operate at least one of the control elements with the same hand. The system may also include a user interface that comprises a D-controller and a touch screen. | 11-15-2012 |
20130006110 | MODULAR APPARATUS FOR DIAGNOSTIC ULTRASOUND - A modular diagnostic ultrasound apparatus is provided comprising a core unit, system electronics and an I/O port. The core unit comprises a housing and a system electronics package within the housing. The system electronics has one or more concatenated filters, including a front end transmit/receive circuit, a processor, a back end circuit for scan conversion, a system clock and a programmable system memory device. There is at least one I/O port connected to the front end and the back end of the system electronics package and extending through the core unit housing wherein all system data processing information is transmitted or received through the I/O port. | 01-03-2013 |
20130010908 | IMPLIED CLOCK - Systems and methods providing clocking between various components or sub-components are shown. Embodiments implement an implied clock technique which reduces the number of signal lines, signaling overhead required for an encoded clock signal, and/or and power consumption for a high speed communication link. In accordance with embodiments efficient communication is provided between a core device and a remote device by the core device providing both clock and data signals to the remote device and the remote device providing a data signal at a predetermined clock rate without communicating its clock signal. The core device of this embodiment determines an “implied clock” suitable for accurately receiving data from the remote device. | 01-10-2013 |
20130245449 | BALANCE BODY ULTRASOUND SYSTEM - The present invention relates to a hand held ultrasound system having a balance body, a transducer assembly connected to said balance body via a communication means and a plurality of control elements arranged in an ergonomic fashion on said balance body, such that a user may hold said system and operate at least one of said control elements with the same hand. In particular a medical ultrasound system comprising a balance body incorporating system electronics, a power supply and a user interface wherein the user interface comprises a D-controller and a touch screen and a transducer assembly attached to the balanced body by a cable. The present invention relates to a hand held ultrasound system having a balance body, a transducer assembly connected to said balance body via a communication means and a plurality of control elements arranged in an ergonomic fashion on said balance body, such that a user may hold said system and operate at least one of said control elements with the same hand. In particular a medical ultrasound system comprising a balance body incorporating system electronics, a power supply and a user interface wherein the user interface comprises a D-controller and a touch screen and a transducer assembly attached to the balanced body by a cable. | 09-19-2013 |
20130331694 | BALANCE BODY ULTRASOUND SYSTEM - The present invention relates to a hand held ultrasound system having a balance body, a transducer assembly connected to said balance body via a communication means and a plurality of control elements arranged in an ergonomic fashion on said balance body, such that a user may hold said system and operate at least one of said control elements with the same hand. In particular a medical ultrasound system comprising a balance body incorporating system electronics, a power supply and a user interface wherein the user interface comprises a D-controller and a touch screen and a transducer assembly attached to the balanced body by a cable. | 12-12-2013 |
20140155747 | ULTRASONIC TRANSDUCER - An ultrasound transducer and methods of fabricating and using the ultrasound transducer. The ultrasound transducer includes a composite layer having a first surface and comprising a plurality of piezoelectric elements separated by isolating material filled kerfs. The composite layer is configured so that the first surface includes an exposed face of each element of the plurality of piezoelectric elements. The transducer further includes a plurality of electrodes defined on the first surface, the electrodes having boundaries configured so that none of the exposed faces are in contact with more than one of the plurality of electrodes. The electrodes may be defined in a conductive layer deposited on the first surface of the composite body by forming a channel in the conductive layer that is aligned vertically with the dielectric kerfs. The transducer may be used to scan a treatment region with both HIFU and imaging ultrasound signals. | 06-05-2014 |
Patent application number | Description | Published |
20100234728 | ULTRASOUND GUIDED HIGH INTENSITY FOCUSED ULTRASOUND TREATMENT OF NERVES - A method for using high intensity focused ultrasound (HIFU) to treat neurological structures to achieve a desired therapeutic affect. Depending on the dosage of HIFU applied, it can have a reversible or irreversible effect on neural structures. For example, a relatively high dose of HIFU can be used to permanently block nerve function, to provide a non-invasive alternative to severing a nerve to treat severe spasticity. Relatively lower doses of HIFU can be used to reversibly block nerve function, to alleviate pain, to achieve an anesthetic effect, or to achieve a cosmetic effect. Where sensory nerves are not necessary for voluntary function, but are involved in pain associated with tumors or bone cancer, HIFU can be used to non-invasively destroy such sensory nerves to alleviate pain without drugs. Preferably, ultrasound imaging synchronized to the HIFU therapy is used to provide real-time ultrasound image guided HIFU therapy of neural structures. | 09-16-2010 |
20110009734 | IMAGE GUIDED HIGH INTENSITY FOCUSED ULTRASOUND TREATMENT OF NERVES - A method for using high intensity focused ultrasound (HIFU) to treat neurological structures to achieve a desired therapeutic effect. Depending on the dosage of HIFU applied, it can have a reversible or irreversible effect on neural structures. For example, a relatively high dose of HIFU can be used to permanently block nerve function, to provide a non-invasive alternative to severing a nerve to treat severe spasticity. Relatively lower doses of HIFU can be used to reversibly block nerve function, to alleviate pain, to achieve an anesthetic effect, or to achieve a cosmetic effect. Where sensory nerves are not necessary for voluntary function, but are involved in pain associated with tumors or bone cancer, HIFU can be used to non-invasively destroy such sensory nerves to alleviate pain without drugs. Preferably, ultrasound imaging synchronized to the HIFU therapy is used to provide real-time ultrasound image guided HIFU therapy of neural structures. | 01-13-2011 |
20110040171 | IMAGE GUIDED HIGH INTENSITY FOCUSED ULTRASOUND TREATMENT OF NERVES - A method for using high intensity focused ultrasound (HIFU) to treat neurological structures to achieve a desired therapeutic effect. Depending on the dosage of HIFU applied, it can have a reversible or irreversible effect on neural structures. For example, a relatively high dose of HIFU can be used to permanently block nerve function, to provide a non-invasive alternative to severing a nerve to treat severe spasticity. Relatively lower doses of HIFU can be used to reversibly block nerve function, to alleviate pain, to achieve an anesthetic effect, or to achieve a cosmetic effect. Where sensory nerves are not necessary for voluntary function, but are involved in pain associated with tumors or bone cancer, HIFU can be used to non-invasively destroy such sensory nerves to alleviate pain without drugs. Preferably, ultrasound imaging synchronized to the HIFU therapy is used to provide real-time ultrasound image guided HIFU therapy of neural structures. | 02-17-2011 |
20110040214 | IMAGE GUIDED HIGH INTENSITY FOCUSED ULTRASOUND TREATMENT OF NERVES - A method for using high intensity focused ultrasound (HIFU) to treat neurological structures to achieve a desired therapeutic effect. Depending on the dosage of HIFU applied, it can have a reversible or irreversible effect on neural structures. For example, a relatively high dose of HIFU can be used to permanently block nerve function, to provide a non-invasive alternative to severing a nerve to treat severe spasticity. Relatively lower doses of HIFU can be used to reversibly block nerve function, to alleviate pain, to achieve an anesthetic effect, or to achieve a cosmetic effect. Where sensory nerves are not necessary for voluntary function, but are involved in pain associated with tumors or bone cancer, HIFU can be used to non-invasively destroy such sensory nerves to alleviate pain without drugs. Preferably, ultrasound imaging synchronized to the HIFU therapy is used to provide real-time ultrasound image guided HIFU therapy of neural structures. | 02-17-2011 |
20120316426 | IMAGE GUIDED HIGH INTENSITY FOCUSED ULTRASOUND TREATMENT OF NERVES - A method for using high intensity focused ultrasound (HIFU) to treat neurological structures to achieve a desired therapeutic effect. Depending on the dosage of HIFU applied, it can have a reversible or irreversible effect on neural structures. For example, a relatively high dose of HIFU can be used to permanently block nerve function, to provide a non-invasive alternative to severing a nerve to treat severe spasticity. Relatively lower doses of HIFU can be used to reversibly block nerve function, to alleviate pain, to achieve an anesthetic effect, or to achieve a cosmetic effect. Where sensory nerves are not necessary for voluntary function, but are involved in pain associated with tumors or bone cancer, HIFU can be used to non-invasively destroy such sensory nerves to alleviate pain without drugs. Preferably, ultrasound imaging synchronized to the HIFU therapy is used to provide real-time ultrasound image guided HIFU therapy of neural structures. | 12-13-2012 |
Patent application number | Description | Published |
20080209551 | File Conversion in Restricted Process - Embodiments are described for removing malicious code from a file in a first file format by converting the file into a converted file of a second file format. In embodiments, converting the file eliminates malicious code embedded within the file from being stored in the converted file. The conversion is performed within a restricted computer process that has restricted privileges limiting its access to an operating system and an underlying computer system. As a result, even if malicious code embedded within the file executes while the file is being converted into the converted file, the damage to a computer system is mitigated because of the limited privileges provided to the restricted process. | 08-28-2008 |
20080243892 | Automatic file conversion to a target format - A conversion tool that is automatically launched enables file formats not understood by a given application to be opened by that application. The converter registers for file types that are not already associated with an application used by the system. When a file that is not supported by another application is opened, the converter automatically converts the file to the target format and then opens the file causing the application that is registered for the target format to be launched. | 10-02-2008 |
20090172709 | Text Editor Virtual Backing Store - At an interface between a text engine and a first client application, text and first client application properties associated with the text may be received from the first client application. Then the interface may map the first client application properties associated with the text to text engine properties associated with the text. Next, the interface may provide the text and the text engine properties associated with the text to the text engine. The text engine may process the text. Next, the text engine may provide the processed text and the text engine properties associated with the processed text to the interface. The interface may then map the text engine properties associated with the processed text to the first client application properties associated with the processed text. The interface may then provide the processed text and the first client application properties associated with the processed text to the first client application. | 07-02-2009 |
20100299371 | AUTOMATIC FILE CONVERSION TO A TARGET FORMAT - A conversion tool that is automatically launched enables file formats not understood by a given application to be opened by that application. The converter registers for file types that are not already associated with an application used by the system. When a file that is not supported by another application is opened, the converter automatically converts the file to the target format and then opens the file causing the application that is registered for the target format to be launched. | 11-25-2010 |
20140136578 | TECHNIQUES TO MANAGE VIRTUAL FILES - Techniques to manage virtual files are described. An apparatus may comprise a processor circuit and a virtual file application operative on the processor circuit to manage file operations for a virtual file, the virtual file comprising a set of calls to one or more file services arranged to manage file information for the virtual file, the file information comprising a content block or content block instructions for a content block associated with the virtual file. Other embodiments are described and claimed. | 05-15-2014 |
20140215302 | COLLABORATION USING MULTIPLE EDITORS OR VERSIONS OF A FEATURE - A system is provided in which access to documents and collaboration across varied platforms and feature versions is supported. A conversion and merge services is described that enables a client device to display documents irrespective of the original file format and re-integrate into the original document the modifications of the displayed document. The displayed document (as a whole or in parts) can be imported and converted to the file format of the original document before the changes are compared and merged into the original document. A set of application programming interfaces are also provided that perform certain tasks, such as highlight, comment, or format. | 07-31-2014 |
20140215303 | APPLICATION PROGRAMMING INTERFACES FOR CONTENT CURATION - Content curation can be facilitated by an application programming interface (API) for creating an address for a block of content in a document identified through a location identifier as well as APIs for retrieving content from the created address and pushing or merging the content back to the created address. Access services including conversion and merge services can be used to provide the content blocks in a suitable format for various clients. A document view is described in which a plurality of content blocks are presented as a single document even though the content blocks may be retrieved using at least two uniform resource locators (URLs). | 07-31-2014 |
20140215391 | VIRTUAL LIBRARY PROVIDING CONTENT ACCESSIBILITY IRRESPECTIVE OF CONTENT FORMAT AND TYPE - A virtual library of content is provided that makes it appear that the content is all of a supported file type for a particular client accessing the virtual library. When the virtual library is displayed at a client device, the content appears as if it is available in the appropriate format for the client device irrespective of the content's actual format. Content selected from a content library interface for the virtual library is provided in the appropriate format for the client device through the automatic invoking of a content access service. The content access service can determine the appropriate consumption format for the client device and convert to a supported file format any content that is in a non-supported format before providing the content to the client device. | 07-31-2014 |
Patent application number | Description | Published |
20090062353 | Alkynyl phenyl derivative compounds for treating ophthalmic diseases and disorders - Provided are alkynyl phenyl derivative compounds, pharmaceutical compositions thereof, and methods of treating ophthalmic diseases and disorders, such as age-related macular degeneration and Stargardt's Disease, using said compounds and compositions. | 03-05-2009 |
20090131374 | PROTEIN TYROSINE PHOSPHATASE INHIBITORS AND METHODS OF USE THEREOF - The present invention provides compounds of Formula (I) and Formula (II) that are useful for modulating the biological activity of the protein tyrosine phosphatase-1b (PTP1B) enzyme. Compounds of this invention can be used to treat diseases and/or conditions in which the PTP1B enzyme is a factor. Such diseases and/or conditions include, but are not limited to, Type 1 diabetes, Type 2 diabetes, inadequate glucose tolerance, insulin resistance, obesity, hyperlipidemia, hypertriglyceridemia, hypercholesterolemia, low HDL levels, atherosclerosis, vascular restenosis, inflammatory bowel disease, pancreatitis, adipose cell tumors, adipose cell carcinoma, liposarcoma, dyslipidemia, cancer, and neurodegenerative diseases. | 05-21-2009 |
20090326074 | Alkoxy compounds for disease treatment - The present invention relates generally to compositions and methods for treating neurodegenerative diseases and disorders, particularly ophthalmic diseases and disorders. Provided herein are alkoxyl derivative compounds and pharmaceutical compositions comprising these compounds. The subject compositions are useful for treating and preventing ophthalmic diseases and disorders, including age-related macular degeneration (AMD) and Stargardt's Disease. | 12-31-2009 |
20120004269 | Alkynyl Phenyl Derivative Compounds for Treating Ophthalmic Diseases and Disorders - Provided are alkynyl phenyl derivative compounds, pharmaceutical compositions thereof, and methods of treating ophthalmic diseases and disorders, such as age-related macular degeneration and Stargardt's Disease, using said compounds and compositions. | 01-05-2012 |
20120122938 | Alkoxy Compounds for Disease Treatment - The present invention relates generally to compositions and methods for treating neurodegenerative diseases and disorders, particularly ophthalmic diseases and disorders. Provided herein are alkoxyl derivative compounds and pharmaceutical compositions comprising these compounds. The subject compositions are useful for treating and preventing ophthalmic diseases and disorders, including age-related macular degeneration (AMD) and Stargardt's Disease. | 05-17-2012 |
20120129894 | Alkoxy Compounds for Disease Treatment - The present invention relates generally to compositions and methods for treating neurodegenerative diseases and disorders, particularly ophthalmic diseases and disorders. Provided herein are alkoxyl derivative compounds and pharmaceutical compositions comprising these compounds. The subject compositions are useful for treating and preventing ophthalmic diseases and disorders, including age-related macular degeneration (AMD) and Stargardt's Disease. | 05-24-2012 |
20120214852 | Alkoxy Compounds for Disease Treatment - The present invention relates generally to compositions and methods for treating neurodegenerative diseases and disorders, particularly ophthalmic diseases and disorders. Provided herein are alkoxyl derivative compounds and pharmaceutical compositions comprising these compounds. The subject compositions are useful for treating and preventing ophthalmic diseases and disorders, including age-related macular degeneration (AMD) and Stargardt's Disease. | 08-23-2012 |
20130018077 | ALKYNYL PHENYL DERIVATIVE COMPOUNDS FOR TREATING OPHTHALMIC DISEASES AND DISORDERS - Provided are alkynyl phenyl derivative compounds, pharmaceutical compositions thereof, and methods of treating ophthalmic diseases and disorders, such as age-related macular degeneration and Stargardt's Disease, using said compounds and compositions. | 01-17-2013 |
20130030026 | ALKYNYL PHENYL DERIVATIVE COMPOUNDS FOR TREATING OPHTHALMIC DISEASES AND DISORDERS - Provided are alkynyl phenyl derivative compounds, pharmaceutical compositions thereof, and methods of treating ophthalmic diseases and disorders, such as age-related macular degeneration and Stargardt's Disease, using said compounds and compositions. | 01-31-2013 |
20130197096 | ALKOXY COMPOUNDS FOR DISEASE TREATMENT - The present invention relates generally to compositions and methods for treating neurodegenerative diseases and disorders, particularly ophthalmic diseases and disorders. Provided herein are alkoxyl derivative compounds and pharmaceutical compositions comprising these compounds. The subject compositions are useful for treating and preventing ophthalmic diseases and disorders, including age-related macular degeneration (AMD) and Stargardt's Disease. | 08-01-2013 |
20140213617 | ALKYNYL PHENYL DERIVATIVE COMPOUNDS FOR TREATING OPHTHALMIC DISEASES AND DISORDERS - Provided are alkynyl phenyl derivative compounds, pharmaceutical compositions thereof, and methods of treating ophthalmic diseases and disorders, such as age-related macular degeneration and Stargardt's Disease, using said compounds and compositions. | 07-31-2014 |
20150045444 | ALKYNYL PHENYL DERIVATIVE COMPOUNDS FOR TREATING OPHTHALMIC DISEASES AND DISORDERS - Provided are alkynyl phenyl derivative compounds, pharmaceutical compositions thereof, and methods of treating ophthalmic diseases and disorders, such as age-related macular degeneration and Stargardt's Disease, using said compounds and compositions. | 02-12-2015 |
Patent application number | Description | Published |
20150133675 | PDE10 INHIBITORS AND RELATED COMPOSITIONS AND METHODS - Compounds that inhibit PDE10 are disclosed that have utility in the treatment of a variety of conditions, including (but not limited to) psychotic, anxiety, movement disorders and/or neurological disorders such as Parkinson's disease, Huntington's disease, Alzheimer's disease, encephalitis, phobias, epilepsy, aphasia, Bell's palsy, cerebral palsy, sleep disorders, pain, Tourette's syndrome, schizophrenia, delusional disorders, drug-induced psychosis and panic and obsessive-compulsive disorders. Pharmaceutically acceptable salts, stereoisomers, solvates and prodrugs of the compounds are also provided. Also disclosed are compositions containing a compound in combination with a pharmaceutically acceptable carrier, as well as methods relating to the use thereof for inhibiting PDE10 in a warm-blooded animal in need of the same. | 05-14-2015 |
Patent application number | Description | Published |
20110224202 | PDE10 INHIBITORS AND RELATED COMPOSITIONS AND METHODS - Compounds that inhibit PDE10 are disclosed that have utility in the treatment of a variety of conditions, including (but not limited to) psychotic, anxiety, movement disorders and/or neurological disorders such as Parkinson's disease, Huntington's disease, Alzheimer's disease, encephalitis, phobias, epilepsy, aphasia, Bell's palsy, cerebral palsy, sleep disorders, pain, Tourette's syndrome, schizophrenia, delusional disorders, drug-induced psychosis and panic and obsessive-compulsive disorders. Pharmaceutically acceptable salts, stereoisomers, solvates and prodrugs of the compounds are also provided. Also disclosed are compositions containing a compound in combination with a pharmaceutically acceptable carrier, as well as methods relating to the use thereof for inhibiting PDE10 in a warm-blooded animal in need of the same. | 09-15-2011 |
20130196994 | PDE10 INHIBITORS AND RELATED COMPOSITIONS AND METHODS - Compounds that inhibit PDE10 are disclosed that have utility in the treatment of a variety of conditions, including (but not limited to) psychotic, anxiety, movement disorders and/or neurological disorders such as Parkinson's disease, Huntington's disease, Alzheimer's disease, encephalitis, phobias, epilepsy, aphasia, Bell's palsy, cerebral palsy, sleep disorders, pain, Tourette's syndrome, schizophrenia, delusional disorders, drug-induced psychosis and panic and obsessive-compulsive disorders. Pharmaceutically acceptable salts, stereoisomers, solvates and prodrugs of the compounds are also provided. Also disclosed are compositions containing a compound in combination with a pharmaceutically acceptable carrier, as well as methods relating to the use thereof for inhibiting PDE10 in a warm-blooded animal in need of the same. | 08-01-2013 |
20140323530 | AMINE DERIVATIVE COMPOUNDS FOR TREATING OPHTHALMIC DISEASES AND DISORDERS - Provided are amine derivative compounds, pharmaceutical compositions thereof, and methods of treating ophthalmic diseases and disorders, such as age-related macular degeneration and Stargardt's Disease, using said compounds and compositions. | 10-30-2014 |