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Liselotte
Liselotte Brix, Bagsvaerd DK
| Patent application number | Description | Published |
|---|---|---|
| 20100168390 | MHC MULTIMERS, METHODS FOR THEIR GENERATION, LABELING AND USE - The present invention describes novel methods to generate MHC multimers and methods to improve existing and new MHC multimers. The invention also describes improved methods for the use of MHC multimers in analysis of T-cells in samples including diagnostic and prognostic methods. Furthermore the use of MHC multimers in therapy are described, e.g. anti-tumour and anti-virus therapy, including isolation of antigen specific T-cells capable of inactivation or elimination of undesirable targeT-cells or isolation of specific T-cells capable of regulation of other immune cells. | 07-01-2010 |
| 20100226854 | MHC Peptide Complexes and Uses Thereof in Infectious Diseases - Novel compounds carrying ligands capable of binding to counter receptors on relevant target cells are disclosed. The compounds possess a number of advantageous features, rendering them very suitable for a wide range of applications, including use as detection systems, detection of relevant target cells as well as a number of other methods. In particular, novel MHC complexes comprising one or more MHC molecules are disclosed. The affinity and specificity of the MHC-peptide complexes are surprisingly high. The possibility of presenting to the target cells a plurality of MHC-peptide complexes makes the MHC complexes according to the present invention an extremely powerful tool e.g. in the field of therapy and diagnosis. The invention generally relates to the field of therapy, including therapeutic methods and therapeutic compositions. Also comprised by the present invention is the sample-mounted use of MHC complexes and MHC multimers. | 09-09-2010 |
| 20100248257 | Compiled Methods for Analysing and Sorting Samples - The present invention relates to the fields of analysis, diagnostics, prognostics, standardization, characterization and enumeration of entities such as biological cells, as well as therapeutical applications. Accordingly, the present invention in preferred aspects is directed to methods for the detection and/or analysis and/or isolation and optionally further manipulation of entities, such as cells, particles, and supra-molecular structures. | 09-30-2010 |
Liselotte Hansen, Herlev DK
| Patent application number | Description | Published |
|---|---|---|
| 20110201639 | STABILIZED TACROLIMUS COMPOSITION - The invention relates to a stable pharmaceutical composition comprising comprising a solid dispersion of tacrolimus in a vehicle further comprising a stabilizing agent capable of providing a pH below 7 in the composition, as measured after re-dispersion in water, and preventing or reducing the formation upon storage of major degradation products of tacrolimus, in particular the 8-epitacrolimus. | 08-18-2011 |
Liselotte Kaiser, Stockholm SE
| Patent application number | Description | Published |
|---|---|---|
| 20090156427 | Bio-Sensing Nanodevice - The invention provides a bio-sensing nanodevice comprising: a stabilized biologically-derived G-protein coupled receptor—the olfactory receptor—on a support, a real time receptor-ligand binding detection method, an odorant delivery system and an odorant recognition program. The biologically-derived G-protein coupled receptor can be stabilized on nanotechnology using surfactant peptide. The said nanodevice provides a greater surface area for better precision and sensitivity to odorant detection. The invention further provides a microfluidic chip containing a stabilized biologically-derived G-protein coupled receptor—the olfactory receptor—immobilized on a support, and arranged in at least two dimensional microarray system. The invention also provides a method of delivering odorant comprising the step of manipulating the bubbles in complex microfluidic networks wherein the bubbles travel in a microfluidic channel carrying a variety of gas samples to a precise location on a chip. The invention further provides method of fabricating hOR17-4 olfactory receptor. | 06-18-2009 |
Liselotte Öhberg, Sodertalje SE
| Patent application number | Description | Published |
|---|---|---|
| 20090131468 | Bis-(Sulfonylamino) Derivatives in Therapy 065 - The invention provides compounds of formula | 05-21-2009 |
| 20090281138 | Bis-(Sulfonylamino) Derivatives in Therapy 066 - The invention provides compounds of formula | 11-12-2009 |
| 20100292279 | Bis-(Sulfonylamino) Derivatives in Therapy - The invention provides compounds of formula | 11-18-2010 |
| 20110021540 | Bis-(Sulfonylamino) Derivatives in Therapy 066 - The invention provides compounds of formula wherein R | 01-27-2011 |
| 20110059992 | New Compounds - This invention relates to novel compounds having the structural formula I below: | 03-10-2011 |
Liselotte Öhberg, Sodertalje SE
| Patent application number | Description | Published |
|---|---|---|
| 20100292279 | Bis-(Sulfonylamino) Derivatives in Therapy - The invention provides compounds of formula | 11-18-2010 |
| 20110059992 | New Compounds - This invention relates to novel compounds having the structural formula I below: | 03-10-2011 |