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| 20090112825 | ENTITY RELATION MINING APPARATUS AND METHOD - The present invention provides a relation mining apparatus and method for mining data for time-series relations and events among texts in various forms such as news, blogs, industrial reports and technical papers which may refer to various relations. According to the present invention, it is possible to automatically extract entity relation instances from a large amount of the texts as described above originating from the Internet or other mediums, mine for time-series entity relations, relation scores and entity importances in various categories based on the extracted instances, and finally extract important events therefrom. Also, according to the present invention, it is possible to perform calculating on the above extracted time-series relations for the corporation entities and business relations, so as to achieve an analysis on Five Forces. Further, it is also possible to present the result to final users by a visualizing module. | 04-30-2009 |
| 20090119336 | APPARATUS AND METHOD FOR CATEGORIZING ENTITIES BASED ON TIME-SERIES RELATION GRAPHS - The present invention provides an apparatus and a method for categorizing entities based on time-series relation graphs. In each of the time-series relation graphs within a prescribed time period, nodes represent entities, and links between the nodes represent entity relations in a corresponding time unit. The inventive apparatus for categorizing entities based on time-series relation graphs comprises: a time-series relation graph categorizing means for categorizing the nodes in each of the time-series relation graphs to generate a node category result for the corresponding time unit in time sequence; and a category result post-processing means for post-processing all the node category results for the corresponding time units in time sequence generated by the time-series relation graph categorizing means to generate finally categorized nodes. | 05-07-2009 |
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| 20080200441 | ESTROGEN RECEPTOR MODULATORS ASSOCIATED PHARMACEUTICAL COMPOSITIONS AND METHODS OF USE - Selective estrogen receptor modulators, as well their related pharmaceutical compositions and methods of use, are provided herein. These estrogen receptor modulators include compounds that primarily exhibit estrogen receptor antagonist activity or primarily exhibit selective estrogen receptor antagonist and agonist activity, i.e., SERM activity, in specific tissue types. Particular embodiments provide compounds that behave as NeuroSERMs promoting neurotrophism and neuroprotection in brain tissue. These NeuroSERMs represent a subset of the modulators compounds provided herein that can cross the blood-brain-barrier and exert estrogen receptor agonist-like effects in the brain. The compounds should be useful for treating a variety of diseases, particularly estrogen receptor-mediated diseases and disorders, such as osteoporosis, breast and endometrial cancers, atherosclerosis and Alzheimer's disease. | 08-21-2008 |
| 20100113586 | PHYTOESTROGENIC FORMULATIONS FOR ALLEVIATION OR PREVENTION OF MENOPAUSAL SYMPTOMS - Select phytoestrogen pharmaceutical compositions and methods of use for preventing or reducing one or more symptoms associated with pre menopause, menopause, and/or post menopause are described herein. These select phytoestrogen formulations are composed only of two or more plant-derived estrogenic molecules and/or their structural analogues and exhibit binding preference to ERβ over ERα and agonist activity in the brain. These ERβ-selective phytoestrogen formulations cross the blood-brain-barrier and promote estrogen-associated neurotrophism and neuroprotection mechanisms in the brain, without activating proliferative mechanisms in the reproductive tissues and are therefore devoid of other estrogen-associated problematic aspects. The formulations can be administered enterally, transdermally, transmucosally, intranasally or parenterally. The formulations preferably contain combinations of compounds, and can be formulated for daily, sustained, delayed or weekly/monthly administration. In a preferred embodiment, these are administered to women who are in menopause or post menopausal, most preferably early in menopausal. | 05-06-2010 |
| 20110091435 | PHYTOESTROGENIC FORMULATIONS FOR ALLEVIATION OR PREVENTION OF HAIR LOSS - Select phytoestrogen pharmaceutical compositions and methods of use for preventing or reducing one or more symptoms associated with hair loss or prostate cancer/prostate hypertrophy are described herein. These select phytoestrogen formulations are preferably composed only of two or more plant-derived estrogenic molecules and/or their structural analogues and exhibit binding preference to ERβ over ERα and agonist activity in non-reproductive tissues including brain. | 04-21-2011 |
