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Liora
Liora Almany, Atlit IL
| Patent application number | Description | Published |
|---|---|---|
| 20110038828 | MATRIX COMPOSED OF A NATURALLY-OCCURRING PROTEIN BACKBONE CROSS LINKED BY A SYNTHETIC POLYMER AND METHODS OF GENERATING AND USING SAME - A method of treating a disorder characterized by tissue damage is provided. The method comprising providing to a subject in need-thereof a composition which comprises a synthetic polymer attached to denatured fibrinogen or a therapeutic portion of the fibrinogen, the composition being formulated for releasing the therapeutic portion of the fibrinogen in a pharmacokinetically regulated manner, thereby treating the disorder characterized by tissue damage or malformation. | 02-17-2011 |
| 20120020911 | MATRIX COMPOSED OF A NATURALLY-OCCURRING PROTEIN BACKBONE CROSS LINKED BY A SYNTHETIC POLYMER AND METHODS OF GENERATING AND USING SAME - The present invention relates to biodegradable scaffolds composed of a naturally-occurring protein backbone cross-linked by a synthetic polymer. Specifically, the present invention provides PEGylated-fibrinogen scaffold and methods of generating and using same for treating disorders requiring tissue regeneration. | 01-26-2012 |
Liora Amkie, Beverly Hills, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20120111357 | HAIR CURLER DEVICE - The present invention provides, in at least one embodiment, a customized hair curler with a barrel, and a handle that fits multiple types of barrels, the barrels being detachable and attachable. The handle has a release latch that allows a quick and simple detachment of the barrel from the handle, and a rotation switch for bidirectional rotation of the barrel with respect to the handle. The hair curler also has a heater and a user control interface for precise temperature control of the heater. | 05-10-2012 |
Liora Braiman-Wiksman, Rishon Lezion IL
| Patent application number | Description | Published |
|---|---|---|
| 20100215634 | VISFATIN THERAPEUTIC AGENTS FOR THE TREATMENT OF ACNE AND OTHER CONDITIONS - The present disclosure relates to compositions and methods for treating acne and other conditions. In particular, the compositions and methods are useful for the treatment of sebum associated conditions. | 08-26-2010 |
| 20100310542 | Pharmaceutical Compositions for treating wouds and related methods - The present disclosure relates to compositions and methods for accelerating the healing process of wounds, increasing the closure of skin wounds, and decreasing inflammation at the site of a skin wound. Specifically, the disclosure relates to compositions comprising a delta-PKC activator, an alpha-PKC inhibitor, and a pharmaceutically acceptable carrier that is free of Ca | 12-09-2010 |
| 20120020917 | METHODS FOR ACCELERATING WOUND HEALING BY ADMINISTRATION OF ADIPOKINES - Methods for inducing or accelerating a healing process of a damaged skill or skin wounds are described. The methods include administering to the skin cells colonizing the damaged skin or skin wound a therapeutically effective amount of an adipokine, an adipocyte or preadipocyte modulator, adipocytes, preadipocytes, or stem cells, or transforming the skin cells colonizing the damaged skin or skin wound such as to express and secrete an adipokine, thereby inducing or accelerating the healing process of the damaged skin or skin wound. | 01-26-2012 |
Liora Braiman-Wiksman, Lezion IL
| Patent application number | Description | Published |
|---|---|---|
| 20110021422 | METHOD AND COMPOSITIONS FOR PREVENTION AND TREATMENT OF DIABETIC AND AGED SKIN - Method and compositions are provided for treating or preventing a skin pathology or disorder associated with diabetes and/or aging, by topical administration of at least one agent capable of restoring an impaired physiological condition of the skin associated with said skin pathology or disorder. Examples of such agents include PKC modulating agents, various adipokines and insulin signaling related molecules. In particular, restoration of the subcutaneous adipose tissue can overcome many of the diabetic skin pathologies and aging skin disorders and conditions. | 01-27-2011 |
Liora Cahalon, Givatayim IL
| Patent application number | Description | Published |
|---|---|---|
| 20080311103 | Anti-Inflammatory Peptides and Methods of Use Thereof - Anti-inflammatory peptides derived from naturally occurring digests of proteins including apolipoprotein A-I, apolipoprotein A-II, fibrinogen γ chain, fibrinogen Aa, low-density lipoprotein receptor, ADAM 8, cadherin 4, and calcitonin receptor are provided, along with pharmaceutical compositions comprising same and methods of treating inflammatory diseases using same. | 12-18-2008 |
Liora Cahalon, Givataim IL
| Patent application number | Description | Published |
|---|---|---|
| 20080274998 | Disaccharide Molecules and Derivatives Thereof and Methods of Using Same - The present invention is of a method and compounds for mediating a biological activity mediated by moesin, and in particular, for such a method and compounds for mediating a biological activity that is capable of being mediated through binding of a disaccharide to moesin. | 11-06-2008 |
Liora Sklair-Tavron, Zichron Yaakov IL
| Patent application number | Description | Published |
|---|---|---|
| 20110312900 | BChE ALBUMIN FUSIONS FOR THE TREATMENT OF COCAINE ABUSE - A method of attenuating a biological effect of cocaine exposure in a primate. Such method includes administering to the primate an amount of a BChE-albumin fusion protein comprising the amino acid substitutions A227S, S315G, A356W, and Y360G, wherein the amount of the fusion protein is effective to cause attenuation of the biological effect of cocaine exposure in the primate. | 12-22-2011 |
Liora Strichman-Almashanu, Baltimore, MD US
| Patent application number | Description | Published |
|---|---|---|
| 20100273658 | Methods for Assaying Gene Imprinting and Methylated CpG Islands - Genomic imprinting is a parent of origin-dependent gene silencing that involves marking of alleles in the germline and differential expression in somatic cells of the offspring. Imprinted genes and abnormal imprinting have been implicated in development, human disease, and embryonic stem cell transplantation. We have established a model system for genomic imprinting using pluripotent 8.5 d.p.c. mouse embryonic germ (EG) cell lines derived from an interspecific cross. We find that allele-specific imprinted gene expression has been lost in these cells. However, partial restoration of allele-specific silencing can occur for some imprinted genes after in vitro differentiation of EG cells into somatic cell lineages, indicating the presence of a gametic memory that is separable from allele-specific gene silencing. We have also generated a library containing most methylated CpG islands. A subset of these clones was analyzed and revealed a subdivision of methylated CpG islands into 4 distinct subtypes: CpG islands belonging to high copy number repeat families; unique CpG islands methylated in all tissues; unique methylated CpG islands that are unmethylated in the paternal germline; and unique CpG islands methylated in tumors. This approach identifies a methylome of methylated CpG islands throughout the genome. | 10-28-2010 |