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Link, US
Aaron J. Link, Austin, TX US
| Patent application number | Description | Published |
|---|---|---|
| 20100247433 | Use of non-canonical amino acids as metabolic markers for rapidly-dividing cells - The invention provides methods, reagents and systems to preferentially mark fast-proliferating cells/tissues (such as cancer), by incorporating non-natural amino acids into proteins, preferably in vivo, using the endogenous protein synthesis machinery of an organism. The incorporated non-natural amino acids contain reactive groups for further chemical reagents, which may serve as a “handle” to for a number of uses, such as imaging of cancer cells, targeting drugs to preferentially kill cancer cells, and proteomic analysis in the context of large scale or high throughput screening for candidate drug leads that affects the proliferation of a target cell, etc. | 09-30-2010 |
Alexander Link, Dallas, TX US
| Patent application number | Description | Published |
|---|---|---|
| 20110086353 | Identification of MicroRNAs (miRNAs) in Fecal Samples as Biomarkers for Gastroenterological Cancers - A simple, rapid, inexpensive, and promising commercial biomarker assay method for multiple diseases is described herein. The present invention detects miRNA-based biomarkers in human stool specimens. The method of the present invention amplifies miRNA directly from stool specimens without any prior miRNA extraction. Differential expression of specific microRNAs in stool of colorectal cancer CRC and adenoma patients suggest fecal microRNAs as a novel potential biomarker for colorectal neoplasia detection. The method of the present invention has diagnostic, prognostic, and therapeutic relevance for gastroenterological cancers/colorectal cancer and as well as further acquired or hereditary GI diseases. | 04-14-2011 |
Brian Link, Boulder, CO US
| Patent application number | Description | Published |
|---|---|---|
| 20120132597 | CROSS-FLOW FILTRATION WITH TURBULENCE AND BACK-FLUSHING ACTION FOR USE WITH ONLINE CHEMICAL MONITORS - A filtration and monitoring system includes an online monitoring device and a filter block having a chamber therein. An inlet pipe provides fluid to the filter block chamber and has an inlet valve located therein configured to shut off the flow of the fluid through the inlet pipe. An outlet pipe removes fluid from the filter block chamber. A filtered fluid conduit fluidically connects the filter block with the monitoring device. The outlet axis of the outlet pipe is offset from the inlet axis of the inlet pipe such that the fluid undergoes a change of direction while passing through the filter block chamber thereby causing turbulent flow within the filter block chamber. The turbulent flow within the filter block sweeps off particles that accumulate on the filter block chamber-side of the filter element to reduce the buildup of filter cake on the filter element. Closing the inlet valve causes a relatively sharp stop to the flow of fluid through the filter block, resulting in a back-flushing flow of fluid through the filter element from a pressure accumulator located in the filtered fluid conduit to the filter block chamber. The back-flushing flow of fluid dislodges filter cake accumulated on the filter block chamber-side of the filter element. | 05-31-2012 |
Bruce A. Link, Rochester, NY US
| Patent application number | Description | Published |
|---|---|---|
| 20120019841 | DOCUMENT SCANNER - A document scanner ( | 01-26-2012 |
| 20120019874 | METHOD FOR DOCUMENT SCANNING - A method of determining document characteristics prior to processing the document in a document scanner ( | 01-26-2012 |
| 20120044547 | DOCUMENT SCANNER - A document scanner ( | 02-23-2012 |
| 20120044548 | METHOD OF SCANNING DOCUMENTS - A document scanner ( | 02-23-2012 |
Charles J. Link, Clive, IA US
| Patent application number | Description | Published |
|---|---|---|
| 20090060930 | Enhanced immunogenicity of tumor associated antigens by addition of alphaGal epitopes - The invention relates to methods and compositions for causing the selective targeting and killing of tumor cells. The present invention describes prophylactic or therapeutic cancer vaccines based on purified TAA proteins or TAA-derived synthetic peptides altered by chemical, enzymatic or chemo-enzymatic methods to introduce αGal epitopes or αGal glycomimetic epitopes, in order to allow for enhanced opsonization of the antigen by natural anti-αGal antibodies to stimulate TAA capture and presentation, thereby inducing a humoral and cellular immune response to the TAA expressed by a tumor. The animal's immune system thus is stimulated to produce tumor specific cytotoxic cells and antibodies which will attack and kill tumor cells present in the animal. | 03-05-2009 |
| 20110136796 | IDO Inhibitors - Presently provided are compounds according to the formula (I) or (II), and pharmaceutical compositions comprising the compounds, wherein R | 06-09-2011 |
| 20120003251 | ENHANCED IMMUNOGENICITY OF TUMOR ASSOCIATED ANTIGENS BY ADDITION OF ALPHAGAL EPITOPES - The invention relates to methods and compositions for causing the selective targeting and killing of tumor cells. The present invention describes prophylactic or therapeutic cancer vaccines based on purified TAA proteins or TAA-derived synthetic peptides altered by chemical, enzymatic or chemo-enzymatic methods to introduce αGal epi topes or αGal glycomimetic epitopes, in order to allow for enhanced opsonization of the antigen by natural anti-αGal antibodies to stimulate TAA capture and presentation, thereby inducing a humoral and cellular immune response to the TAA expressed by a tumor. The animal's immune system thus is stimulated to produce tumor specific cytotoxic cells and antibodies which will attack and kill tumor cells present in the animal. | 01-05-2012 |
Charles M. Link, Atlanta, GA US
| Patent application number | Description | Published |
|---|---|---|
| 20080259885 | DUAL MODE DEVICE WITH MAC ADDRESS CAPTURE AND PAIRING - Seamless connectivity by a user device between a licensed and an unlicensed network is provided through capturing of MAC address information relating to one or more access points servicing the licensed and/or the unlicensed networks. One or more access points can be chosen as a designated access point. If the access point is available for communication with the device and other device criteria is met, the access point is designated. If designated, when the device is in vicinity of the access point seamless and transparent connectivity is automatically established with that access point. | 10-23-2008 |
Christian Link, Plano, TX US
| Patent application number | Description | Published |
|---|---|---|
| 20110221416 | Battery charger and method for collecting maximum power from energy harvester circuit - An energy harvesting system for transferring energy from an energy harvester ( | 09-15-2011 |
Darren Link, Lexington, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20090197248 | VITRO EVOLUTION IN MICROFLUIDIC SYSTEMS - The invention describes a method for isolating one or more genetic elements encoding a gene product having a desired activity, comprising the steps of: (a) compartmentalising genetic elements into microcapsules; and (b) sorting the genetic elements which express the gene product having the desired activity; wherein at least one step is under microfluidic control. The invention enables the in vitro evolution of nucleic acids and proteins by repeated mutagenesis and iterative applications of the method of the invention. | 08-06-2009 |
| 20090197772 | Compartmentalised combinatorial chemistry by microfluidic control - The invention describes a method for the synthesis of compounds comprising the steps of: (a) compartmentalising two or more sets of primary compounds into microcapsules; such that a proportion of the microcapsules contains two or more compounds; and (b) forming secondary compounds in the microcapsules by chemical reactions between primary compounds from different sets; wherein one or both of steps (a) and (b) is performed under microfluidic control; preferably electronic microfluidic control The invention further allows for the identification of compounds which bind to a target component of a biochemical system or modulate the activity of the target, and which is co-compartmentalised into the microcapsules. | 08-06-2009 |
| 20100022414 | Droplet Libraries - The present invention generally relates to droplet libraries and to systems and methods for the formation of libraries of droplets. The present invention also relates to methods utilizing these droplet libraries in various biological, chemical, or diagnostic assays. | 01-28-2010 |
| 20110000560 | Manipulation of Microfluidic Droplets - The invention provides methods for assessing one or more predetermined characteristics or properties of a microfluidic droplet within a microfluidic channel, and regulating one or more fluid flow rates within that channel to selectively alter the predetermined microdroplet characteristic or property using a feedback control. | 01-06-2011 |
Darren Link, Guildford, CT US
| Patent application number | Description | Published |
|---|---|---|
| 20090005254 | Compartmentalized Screening by Microfluidic Control - The invention describes a method for the identification of compounds which bind to a target component of a bio-chemical system or modulate the activity of the target, comprising the steps of: a) compartmentalising the compounds into micro-capsules together with the target, such that only a subset of the repertoire is represented in multiple copies in any one microcapsule; and b) identifying the compound which binds to or modulates the activity of the target; wherein at least one step is performed under microfluidic control. The invention enables the screening of large repertoires of molecules which can serve as leads for drug development. | 01-01-2009 |
Darren R. Link, Lexington, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20100137163 | Microfluidic Devices and Methods of Use in The Formation and Control of Nanoreactors - The present invention provides novel microfluidic devices and methods that are useful for performing high-throughput screening assays and combinatorial chemistry. Such methods can include labeling a library of compounds by emulsifying aqueous solutions of the compounds and aqueous solutions of unique liquid labels on a microfluidic device, which includes a plurality of electrically addressable, channel bearing fluidic modules integrally arranged on a microfabricated substrate such that a continuous channel is provided for flow of immiscible fluids, whereby each compound is labeled with a unique liquid label, pooling the labeled emulsions, coalescing the labeled emulsions with emulsions containing a specific cell or enzyme, thereby forming a nanoreactor, screening the nanoreactors for a desirable reaction between the contents of the nanoreactor, and decoding the liquid label, thereby identifying a single compound from a library of compounds. | 06-03-2010 |
| 20100172803 | METHOD AND APPARATUS FOR FLUID DISPERSION - A microfluidic method and device for focusing and/or forming discontinuous sections of similar or dissimilar size in a fluid is provided. The device can be fabricated simply from readily-available, inexpensive material using simple techniques. | 07-08-2010 |
Darren Roy Link, Lexington, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20100105866 | MICROFLUIDIC MANIPULATION OF FLUIDS AND REACTIONS - The present invention relates generally to microfluidic structures, and more specifically, to microfluidic structures and methods including microreactors for manipulating fluids and reactions. In some embodiments, structures and methods for manipulating many (e.g., 1000) fluid samples, i.e., in the form of droplets, are described. Processes such as diffusion, evaporation, dilution, and precipitation can be controlled in each fluid sample. These methods also enable conditions within the fluid samples (e.g., concentration) to be controlled. Manipulation of fluid samples can be useful for a variety of applications, including testing for reaction conditions, e.g., in crystallization, chemical, and biological assays. | 04-29-2010 |
| 20110244455 | DIGITAL ANALYTE ANALYSIS - The invention generally relates to droplet based digital PCR and methods for analyzing a target nucleic acid using the same. In certain embodiments, methods of the invention involve forming sample droplets containing, on average, a single target nucleic acid, amplifying the target in the droplets, excluding droplets containing amplicon from the target and amplicon from a variant of the target, and analyzing target amplicons. | 10-06-2011 |
| 20110250597 | DIGITAL ANALYTE ANALYSIS - The invention generally relates to droplet based digital PCR and methods for analyzing a target nucleic acid using the same. In certain embodiments, methods of the invention involve forming sample droplets containing, on average, a single target nucleic acid, amplifying the target in the droplets, excluding droplets containing amplicon from the target and amplicon from a variant of the target, and analyzing target amplicons. | 10-13-2011 |
| 20120122714 | SANDWICH ASSAYS IN DROPLETS - The invention generally relates to performing sandwich assays in droplets. In certain embodiments, the invention provides methods for detecting a target analyte that involve forming a compartmentalized portion of fluid including a portion of a sample suspected of containing a target analyte and a sample identifier, a first binding agent having a target identifier, and a second binding agent specific to the target analyte under conditions that produce a complex of the first and second binding agents with the target analyte, separating the complexes, and detecting the complexes, thereby detecting the target analyte. | 05-17-2012 |
Darren Roy Link, Guilford, CT US
| Patent application number | Description | Published |
|---|---|---|
| 20090131543 | Method and Apparatus for Forming Multiple Emulsions - The present invention generally relates to multiple emulsions, and to methods and apparatuses for making multiple emulsions. A multiple emulsion generally describes larger droplets that contain one or more smaller droplets therein. The larger droplets may be suspended in a third fluid in some cases. These can be useful for encapsulating species such as pharmaceutical agents, cells, chemicals, or the like. In some cases, one or more of the droplets can change form, for instance, to become solidified to form a microcapsule, a liposome, a polymerosome, or a colloidosome. Multiple emulsions can be formed in one step in certain embodiments, with generally precise repeatability, and can be tailored to include one, two, three, or more inner droplets within a single outer droplet (which droplets may all be nested in some cases). | 05-21-2009 |
David Link, Falls Church, VA US
| Patent application number | Description | Published |
|---|---|---|
| 20100094981 | Dynamically Deployable Self Configuring Distributed Network Management System - Systems, software, and methods for managing networks of connected electronic devices are described. In one example, network management policy and network management applications are transferred automatically upon detection and identification of a new device, protocol or application on the network. In another example, information related to at least one aspect of the network is obtained by an NMAS, and at least one applicable management policy is identified by the NMAS; and the identified policy is used to manage at least one aspect of the network's operation. | 04-15-2010 |
David Link, Shakopee, MN US
| Patent application number | Description | Published |
|---|---|---|
| 20120085019 | PORTABLE, SELF-COOLING BAIT CONTAINER - A live aqueous animal container having: | 04-12-2012 |
David F. Link, Falls Church, VA US
| Patent application number | Description | Published |
|---|---|---|
| 20080228908 | Management techniques for non-traditional network and information system topologies - Systems, software, and methods for managing traditional (i.e., TCP/IP-based), non-traditional, and traditional—non-traditional hybrid networks of connected electronic devices are described. In one example, network management policy and network management applications are downloaded automatically upon detection and identification of a new device, application or service on a network. In another example, information related to at least one aspect of the network is obtained by a network management device through connection to a non-TCP/IP network, or by way of a gateway device or application, at least one applicable management policy is identified, and the identified policy is used to manage at least one aspect of the network's operation. In another example, devices, applications or services presenting various behaviors under various scenarios are evaluated and placed under management. | 09-18-2008 |
Douglas F. Link, Plymouth, MN US
| Patent application number | Description | Published |
|---|---|---|
| 20100034410 | HEARING AID ADAPTED FOR EMBEDDED ELECTRONICS - A hearing aid comprising a microphone, a receiver, hearing aid electronics coupled to the microphone and the receiver, and conductive traces overlaying an insulator, the conductive traces configured to interconnect the hearing aid electronics and to follow non-planar contours of the insulator. Examples are provided wherein the insulator includes a hearing aid housing. | 02-11-2010 |
| 20100158296 | HEARING ASSISTANCE DEVICE WITH STACKED DIE - The present subject matter relates to a hearing assistance device for an ear of a wearer comprising a microphone for receiving sound, hearing assistance electronics in communications with the microphone, the hearing assistance electronics including a hybrid circuit, and a wearable housing adapted to house at least the hearing assistance electronics. The hybrid circuit comprises a first integrated circuit die having one or more through-silicon-vias (TSVs), a first redistribution layer disposed on a surface of the first integrated circuit, and a second integrated circuit die having one or more contacts, the second integrated circuit die disposed on the first redistribution layer, wherein the first redistribution layer is adapted to connect one or more of the one or more TSVs of the first integrated circuit die to one or more of the one or more contacts of the second integrated circuit die. | 06-24-2010 |
Garrett Link, Seattle, WA US
| Patent application number | Description | Published |
|---|---|---|
| 20080281686 | DYNAMIC CONTENT INSERTION METHOD AND SYSTEM - A method and computer program product for initializing an event timer. A first portion of a computer application is executed. After completion of the execution of the first portion of the computer application, it is determined if the event timer has reached a predetermined amount. If the event timer has reached the predetermined amount, a first advertisement is rendered. | 11-13-2008 |
Garry N. Link, Pacific City, OR US
| Patent application number | Description | Published |
|---|---|---|
| 20080272842 | Calibrated feedback - A differential feedback amplifier is provided with a feedback network wherein that feedback network is adjustable so as to improve the PSRR of the amplifier. In another aspect of the present invention, a differential feedback amplifier is provided with a feedback network wherein that feedback network is adjustable so as to improve the CMRR of the amplifier. In a further aspect of the present invention, a Class D amplifier is provided with a passive differential feedback, summing with an input current at a differential virtual ground produced by an amplifier which is a sub-section of the Class D amplifier. | 11-06-2008 |
George Brian Link, Knoxville, TN US
| Patent application number | Description | Published |
|---|---|---|
| 20100253366 | Broadband high impedance pickoff circuit - A measuring system minimizes the parasitic affects of lumped circuit elements. The system includes two or more in-situ interfaces configured to conductively link a source to an internal load and an external load. The in-situ interfaces are linked to a shunt conductor. Two or more linear and dynamic elements conductively link the in-situ interfaces in series. The dynamic elements are configured to overwhelm the parasitic self-capacitance of an input circuit coupled to at least one of the in-situ interfaces. A shield enclosing at least one of the linear and dynamic elements has a conductive surface to fields and electromagnetic interference. The shield has attenuation ratios that substantially dampen the parasitic capacitance between the linear and dynamic elements that bridge some of the in-situ interfaces. | 10-07-2010 |
Gregory Link, Canton, MI US
| Patent application number | Description | Published |
|---|---|---|
| 20120105623 | System for Detecting Surface Variations on Engine Cylinder Head Valve Seats - A machine vision inspection system that detects defects on machined valve seats that may be caused by a broken cutting tool insert. The system also measures the valve seat width to detect a missing cutting tool insert and monitor reactions to cutting tool forces and tool wear. The system uses high resolution cameras and stable LED light sources. A method is disclosed for manufacturing cylinder heads that are 100% inspected inline for valve seat surface defects. | 05-03-2012 |
Jamie R. Link, Arlington, VA US
| Patent application number | Description | Published |
|---|---|---|
| 20080204752 | SYSTEM AND METHOD FOR REMOTE, FREE-SPACE OPTICAL DETECTION OF POTENTIAL THREAT AGENT - A system and method for free space, optical remote sensing of a potential threat agent using spectrally responsive sensor material. In one example the sensor material is formed by particles, which in one particular form are porous photonic crystals. The particles are dispersed into an area being monitored for the presence of the potential threat agent. A pair of lasers is used to generate optical light beams that are directed at the sensor particles after the particles have been dispersed. The light reflected by the sensor particles is then analyzed. The presence of the potential threat agent causes a shift in the spectral peak of light reflected from the sensor particles that can be sensed using photo detectors and a processing subsystem. The system can be tuned to remotely detect for specific chemical, biological or environmental agents that may be present within a given area. | 08-28-2008 |
Jason Link, Portland, OR US
| Patent application number | Description | Published |
|---|---|---|
| 20080260760 | Prostate-Specific Antigen-Derived Mhc Class H-Restricted Peptides and Their Use in Vaccines to Treat or Prevent Prostate Cancer - The present invention relates to immunogenic peptides derived from human prostate cancer antigen (PSA-derived peptides) and their use as vaccines to treat or prevent prostate cancer. The invention is also related to dendritic cells from a patient having prostate cancer, which dendritic cells have been exposed to one or more PSA-derived peptides, and their use to treat or prevent prostate cancer in the patient. The invention is also directed to T-cells from a patient which cells are specific for PSA-activated peptide(s), and their uses to treat or prevent prostate cancer. | 10-23-2008 |
Jeffrey S. Link, Londonderry, NH US
| Patent application number | Description | Published |
|---|---|---|
| 20100249109 | SUBSTITUTED TETRAHYDROPYRAZOLO-PYRIDO-AZEPINE COMPOUNDS - The present invention relates to substituted tetrahydropyrazolo-pyrido-azepine compounds and methods of synthesizing these compounds. The present invention also relates to pharmaceutical compositions containing substituted tetrahydropyrazolo-pyrido-azepine compounds and methods of treating cell proliferative disorders, such as cancer, by administering these compounds and pharmaceutical compositions to subjects in need thereof. | 09-30-2010 |
| 20110166127 | Substituted Benzo-Pyrimido-Tetrazolo-Diazepine Compounds - The present invention relates to substituted benzo-pyrimido-tetrazolo-diazepine compounds and methods of synthesizing these compounds. The present invention also relates to pharmaceutical compositions containing substituted benzo-pyrimido-tetrazolo-diazepine compounds and methods of treating cell proliferative disorders, such as cancer, by administering these compounds and pharmaceutical compositions to subjects in need thereof. | 07-07-2011 |
| 20110245236 | Substituted Benzo-Pyrido-Triazolo-Diazepine Compounds - The present invention relates to substituted benzo-pyrido-triazolo-diazepine compounds and methods of synthesizing these compounds. The present invention also relates to pharmaceutical compositions containing substituted benzo-pyrido-triazolo-diazepine compounds and methods of treating cell proliferative disorders, such as cancer, by administering these compounds or pharmaceutical compositions to subjects in need thereof. | 10-06-2011 |
| 20120015935 | Substituted Tetrahydropyrazolo-Pyrido-Azepine Compounds - The present invention relates to substituted tetrahydropyrazolo-pyrido-azepine compounds and methods of synthesizing these compounds. The present invention also relates to pharmaceutical compositions containing substituted tetrahydropyrazolo-pyrido-azepine compounds and methods of treating cell proliferative disorders, such as cancer, by administering these compounds and pharmaceutical compositions to subjects in need thereof. | 01-19-2012 |
Jeff S. Link, Londonderry, NH US
| Patent application number | Description | Published |
|---|---|---|
| 20090136499 | RAF Inhibitors and Uses Thereof - The present invention provides imidazooxazole and imidazothiazole compounds and their synthesis. The compounds of the present invention are capable of inhibiting the activity of RAF kinase, such as B-RAF | 05-28-2009 |
John Link, Chestnut Ridge, NY US
| Patent application number | Description | Published |
|---|---|---|
| 20080256729 | Teeth Whitening Toothbrush - A toothbrush for enhancing the whiteness of teeth while carrying out normal prophylactic brushing with a material that includes a light/heat activated whitening agent. The whitening agent is usually activated by light of a certain wavelength. The toothbrush comprises a handle and a head and optical transmission material bringing light of a predetermined frequency to the head portion. The head portion has a clear surface into which the bristles are secured so as to cause light to shine on the teeth surfaces as they are being brushed by the bristles. | 10-23-2008 |
John Link, Humble, TX US
| Patent application number | Description | Published |
|---|---|---|
| 20090032768 | WATER-SOLUBLE PHENYLENEDIAMINE COMPOSITIONS AND METHODS FOR STABILIZING ETHYLENICALLY UNSATURATED COMPOUNDS AND MONOMERS - Compositions and methods for inhibiting polymerization of ethylenically unsaturated monomers are provided. The compositions include a water-soluble phenylenediamine composition. | 02-05-2009 |
| 20100258480 | PROCESSES FOR INHIBITING FOULDING IN HYDROCARBON PROCESSING - A method for inhibiting the formation of fouling materials including contacting hydrocarbon media containing carbonyl compounds with hydroxylamine and naphthalene sulfonate while treating the hydrocarbon media with a basic wash. | 10-14-2010 |
| 20110297878 | METHODS AND COMPOSITIONS FOR INHIBITING VINYL AROMATIC MONOMER POLYMERIZATION - Methods and compositions are provided for inhibiting the polymerization of a vinyl aromatic monomer, such as styrene monomer, during elevated temperature processing thereof or during storage or shipment of polymer containing product. The compositions comprise a combination of a quinone methide derivative A) and a phenol compound B). The methods comprise adding from about 1-10,000 ppm of the combination to the monomer containing medium, per one million parts of the monomer. | 12-08-2011 |
John F. Link, Calumet City, IL US
| Patent application number | Description | Published |
|---|---|---|
| 20090013661 | Remote control system and apparatus for enabling accessing the interior of a chamber of a harvester - A remote control system and apparatus enabling safely accessing the interior of a cotton compacting chamber and other regions of a cotton harvester, and also operating aspects of the compacting apparatus contained therein and thereabout, and which system is optionally operable for operating other aspects of the harvester, for inspection, maintenance and/or service, as well as other purposes. The system requires initial steps, including to safely neutralize or lock out operating systems of the harvester, then enables accessing designated interior locations of the compactor and the ability to operate systems therein, including aspects of the compacting apparatus. | 01-15-2009 |
John Robert Link, Wilmington, DE US
| Patent application number | Description | Published |
|---|---|---|
| 20110151461 | DETECTION ALGORITHM FOR PCR ASSAY - The application provides methods for improving the detection accuracy of the binding of labeled nucleic acid probes, such as those used in PCR reactions. One such method comprises measuring the label intensity, e.g. fluorescence, at two different temperatures, a higher temperature and a lower temperature, and then calculating the ratio of the label intensity at the lower temperature over the label intensity at the higher temperature. Another method comprises measuring the label intensity at least two points in time post-PCR and calculating the slope of the label intensity as a function of time. Measuring the hybridization kinetics of the probe binding to the target nucleic acid allows an on-rate slope to be calculated which gives this method good specificity of detection. | 06-23-2011 |
Kenneth Link, Portland, OR US
| Patent application number | Description | Published |
|---|---|---|
| 20080216355 | Lightweight and Flexible Article of Footwear - An article of footwear with an outer member including slots that increase flexibility is disclosed. The outer member also includes an inner plate including a set of protective strips. The inner plate is disposed along an inner surface of the outer member so that the protective strips are aligned with and cover the slots in the outer member. | 09-11-2008 |
| 20100313447 | Lightweight And Flexible Article Of Footwear - An article of footwear with an outer member including slots that increase flexibility is disclosed. The outer member also includes an inner plate including a set of protective strips. The inner plate is disposed along an inner surface of the outer member so that the protective strips are aligned with and cover the slots in the outer member. | 12-16-2010 |
Kevin Link, Atlanta, GA US
| Patent application number | Description | Published |
|---|---|---|
| 20100228404 | Method and system for configuring and provisioning a vehicle - A telematics method and system facilitates customizing a plurality of vehicle content files, parameters, and features based on edits and selections from a user interface. A telematics provider maintains a database comprising a table, or tables that associate(s) user identification information with a vehicle VIN and equipment/features/content installed in/on vehicle devices associated with the VIN. Database updates may occur automatically, or upon a user instruction, when a TCU wirelessly transmits current equipment, content, and feature configuration information to a TOC coupled with the database. The telematics provider's server may provide the interface that facilitates the user logging in and editing features, content, and operational and performance parameters currently configured/installed in/on the vehicle' equipment and devices. The telematics provider may forward the user input from the interface to another provider after it verifies user log in credentials before the other provider begins a download to vehicle devices associated with the VIN. | 09-09-2010 |
Kevin W. Link, Atlanta, GA US
| Patent application number | Description | Published |
|---|---|---|
| 20090222200 | METHODS, SYSTEMS, AND APPARATUSES FOR TELEMATICS NAVIGATION - Provided are methods, systems, and apparatuses for telematics navigation. | 09-03-2009 |
Kristian Hurd Link, Hamden, CT US
| Patent application number | Description | Published |
|---|---|---|
| 20120004115 | SYSTEM AND METHOD FOR PURIFICATION AND USE OF INORGANIC PYROPHOSPHATASE FROM AQUIFEX AEOLICUS - The present invention provides a nucleic acid that comprises a nucleic acid of SEQ ID NO: 1 or 3 encoding an Aae pyrophosphatase protein, an enzyme protein of SEQ ID NO: 2 or 4, and methods of sequencing using an isolated Aae pyrophosphatase protein. | 01-05-2012 |
Matthew Paul Link, Kapolei, HI US
| Patent application number | Description | Published |
|---|---|---|
| 20090187466 | Location-Based Information-Geo Retail Notification - Sales information corresponding to one or more retailers is collected and stored. A customer/user can access the sales information using a client application running on his mobile device. The access may be responsive to a customer profile that establishes the customer's preferences or tastes. The access may be responsive to detecting that the customer's mobile device is within a threshold distance of one or more matching retailers. The access may be responsive to a customer request to obtain the sales information. One or more reminder notes may be sent to the customer to serve as a reminder that the customer likely needs to acquire a product or service. | 07-23-2009 |
Michael A. Link, Hillsboro, OR US
| Patent application number | Description | Published |
|---|---|---|
| 20110154656 | SYSTEMS AND METHODS FOR MANUFACTURING MODIFIED IMPEDANCE COAXIAL CABLES - Systems and methods for manufacturing modified impedance coaxial cables including providing a coaxial cable having an inner conductor, a dielectric layer at least partially covering an outer surface of the inner conductor, and an outer conductor at least partially covering an outer surface of the dielectric layer. The coaxial cable may include a first section having a first impedance configured to allow a first frequency band to pass. A discontinuity section may be formed in at least one of the inner conductor, the dielectric layer, and the outer conductor. The discontinuity section may have an impedance different than the first impedance and a length which is configured to attenuate a second frequency band. | 06-30-2011 |
Michael John Link, St. Paul, MN US
| Patent application number | Description | Published |
|---|---|---|
| 20090132894 | Soft Output Bit Threshold Error Correction - A communications channel is provided that includes an encoder that receives user data and generates corresponding encoded symbols for transmission through a channel medium. A channel detector has an input coupled to receive an output signal from the channel medium and a reliability information output which produces reliability information regarding logic states of detected bits in the output signal. A binary reliability value is provide for each of the detected bits. The channel further includes a decoder having a reliability information input coupled to the reliability information output of the channel detector to generate corresponding user data words as a function of the binary reliability value. | 05-21-2009 |
| 20090132897 | Reduced State Soft Output Processing - An approach to reducing processing of soft output is disclosed. Candidate sequences of bits can be compared to soft output decisions to reduce at least one of the candidate sequences. Branch metric calculations can be performed for remaining candidate sequences and a most likely path can be selected from the remaining candidate sequences. | 05-21-2009 |
Michael L. Link, Byron, GA US
| Patent application number | Description | Published |
|---|---|---|
| 20100285959 | HERBICIDAL MIXTURES - Disclosed is a herbicidal mixture comprising (a) at least one herbicide compound selected from the pyrimidines of Formula 1, including all geometric and stereoisomers, N-oxides, and salts thereof: | 11-11-2010 |
Robert Link, Webster, NY US
| Patent application number | Description | Published |
|---|---|---|
| 20110109675 | PHASE SHIFTS FOR PRINTING AT TWO SPEEDS - The method includes forming first size drops by applying drop forming pulses during a unit time period τ | 05-12-2011 |
| 20110109677 | DYNAMIC PHASE SHIFTS TO IMPROVE STREAM PRINT - A method of forming print drops includes forming drops of a first size by applying drop forming energy pulses during a unit time period, τ | 05-12-2011 |
| 20110109705 | PHASE SHIFTS FOR TWO GROUPS OF NOZZLES - A method includes forming drops of first size by applying drop-forming pulses during unit time period, τ | 05-12-2011 |
| 20110242169 | CONTINUOUS PRINTER WITH ACTUATOR ACTIVATION WAVEFORM - A method for operating a drop generating device for selective formation of large-volume droplets and small-volume droplets, said method includes the steps of defining a small-drop waveform at least a pulse to form a small volume drop; defining a large-drop waveform that includes a set of pulses to form a large volume drop; creating a sequence of waveforms comprising waveforms of the small-drop and large-drop waveforms in response to image data the sequence of waveforms; and selectively inserting a perturbation pulse in the time interval between pulses of any two consecutive waveforms. | 10-06-2011 |
| 20110242170 | METHOD FOR OPERATING CONTINUOUS PRINTERS - A method for operating a continuous inkjet printer, the method includes forming drops with a drop formation period being the time between consecutive drop formations; creating a portion of the drops that strike the print media for forming print drops; creating a portion of the created drops that do not strike the print media for forming catch drops; creating the print drops to print on a series of consecutive pixel locations; wherein a time between the creation of consecutive print drops is inconsistent which causes an additional catch drop so that a gap is created; wherein when a gap is created, adjusting a velocity of the print drop adjacent to the gap to cause the print drop to shift slightly toward the gap. | 10-06-2011 |
| 20110242228 | DROP PLACEMENT METHOD FOR CONTINUOUS PRINTERS - A method for providing drop placement adjustment of drops deposited on a print media by a printhead in a continuous inkjet printer, the method comprising the steps of providing the printhead with a drop generator having at least one nozzle; moving the printhead relative to the print media; causing the printhead to form drops from the at least one nozzle with a drop formation period being the time between consecutive drop formations; wherein a portion of the formed drops are allowed to strike pixel locations on the print media for forming print drops, while other drops are directed toward a catcher and do not strike the print media for forming catch drops; creating a series of the print drops to print on a series of consecutive pixel locations; and adjusting a velocity of a portion of the formed print drops relative to a velocity of other print drops to adjust the placement of the print drop within the pixel locations. | 10-06-2011 |
Ryan Link, Houston, TX US
| Patent application number | Description | Published |
|---|---|---|
| 20110182730 | WIND TURBINE BLADE WITH DAMPING ELEMENT FOR EDGEWISE VIBRATIONS | 07-28-2011 |
Steven G. Link, Rochester, NY US
| Patent application number | Description | Published |
|---|---|---|
| 20090181170 | MONOAZO COLORANTS FROM PYRAZOLOBENZODIAZINEDIOXIDES - The invention relates to monoazo colorants derived from pyrazolobenzodiazinedioxides of Formula 1: | 07-16-2009 |
| 20090205533 | INKJET INKS CONTAINING AZO PYRAZOLOBENZOPYRIMIDINEONE CLASS OF COLORANTS - The present invention relates to an aqueous ink comprising at least water, and a colorant of Formula 1 | 08-20-2009 |