Light, Ii
James Light, Ii, San Diego, CA US
Patent application number | Description | Published |
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20100167294 | METHODS FOR DETECTING NUCLEIC ACIDS IN A SAMPLE - Systems and methods are provided for immobilizing nucleic acid amplicons and protein antigens on a test device. Amplicons comprising a synthetic binding unit and a detectable label are generated and immobilized at predetermined locations on a test device by specific binding interactions between the synthetic binding unit and a synthetic capture unit located at the predetermined locations. The synthetic binding unit may include a unique design such that during amplification, a region of the synthetic binding unit is not subject to the amplification reaction, and thus the amplicon remains single stranded and available for binding to the synthetic capture unit during the capture process. In certain embodiments, the synthetic binding unit and a synthetic capture unit include synthetic nucleic acid analogs that do not interact with native nucleic acids or enzymes that act thereon. In one embodiment the synthetic binding unit and synthetic capture unit comprises puranosyl RNA (pRNA). | 07-01-2010 |
James P. Light, Ii, San Diego, CA US
Patent application number | Description | Published |
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20080305010 | STRIATED CAP - A cap for use in forming a sealed container with a fluid-holding vessel. The cap includes a downwardly tapered inner wall having a plurality of radially extending striations for improving the penetrability of the cap and for facilitating the formation of air passageways. | 12-11-2008 |
20090301230 | METHOD FOR REMOVING A FLUID SUBSTANCE FROM A SEALED COLLECTION DEVICE - A method for removing a fluid substance from a sealed collection device comprising a cap and a fluid-holding vessel, where the method aids in venting air from the collection device when the cap is penetrated by a fluid transfer device used to withdraw a fluid substance from the vessel. Venting is aided by incorporating a pause step between penetrating the cap and contacting the fluid substance held by the vessel with the fluid transfer device or by contacting the cap at a slower speed than the fluid transfer device enters the collection device after the cap has been penetrated. | 12-10-2009 |
20100203547 | METHOD FOR ACCESSING THE CONTENTS OF A CLOSED VESSEL CONTAINING A SPECIMEN RETRIEVAL DEVICE - Method for obtaining a fluid from a collection device assembled to isolate a specimen retrieval device from the pathway of a fluid transfer device used to penetrate a cap of the collection device and to draw and remove the fluid from the collection device for analysis. | 08-12-2010 |
James P. Light, Ii, Middleton, WI US
Patent application number | Description | Published |
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20120262260 | MAGNETIC MICROPARTICLE LOCALIZATION DEVICE - Provided herein is technology relating to processing samples. In particular, the technology provides articles of manufacture, apparatuses, and methods related to purifying an analyte from a sample matrix using magnetic particles. | 10-18-2012 |
20120285900 | SPIN FILTER - Provided herein is technology relating to filtration and particularly, but not exclusively, to filters and methods for filtering by means of centrifugation. | 11-15-2012 |
20120288868 | ISOLATION OF NUCLEIC ACIDS - Provided herein is technology relating to isolating nucleic acids. In particular, the technology relates to methods and kits for extracting nucleic acids from problematic samples such as stool. | 11-15-2012 |
20120288957 | REMOVAL OF PCR INHIBITORS - Provided herein is technology relating to processing and preparing samples and particularly, but not exclusively, to methods, systems, and kits for removing assay inhibitors from samples comprising nucleic acids. | 11-15-2012 |
20130211286 | SAMPLE COLLECTION DEVICE - Provided herein is technology relating to collecting and preparing samples. For example, the technology relates particularly, but not exclusively, to devices, systems, and kits that allow a subject to collect and prepare a sample for analysis. | 08-15-2013 |
20140193813 | ISOLATION OF NUCLEIC ACIDS - Provided herein is technology relating to isolating nucleic acids. In particular, the technology relates to methods and kits for extracting nucleic acids from problematic samples such as stool. | 07-10-2014 |
20140194607 | ISOLATION OF NUCLEIC ACIDS - Provided herein is technology relating to isolating nucleic acids. In particular, the technology relates to methods and kits for extracting nucleic acids from problematic samples such as stool. | 07-10-2014 |
20140194608 | ISOLATION OF NUCLEIC ACIDS - Provided herein is technology relating to isolating nucleic acids. In particular, the technology relates to methods and kits for extracting nucleic acids from problematic samples such as stool. | 07-10-2014 |
20140194609 | ISOLATION OF NUCLEIC ACIDS - Provided herein is technology relating to isolating nucleic acids. In particular, the technology relates to methods and kits for extracting nucleic acids from problematic samples such as stool. | 07-10-2014 |