Inventors list |
Assignees list |
Classification tree browser |
Top 100 Inventors |
Top 100 Assignees |
Liddle
Christopher Liddle, Chatswood AU
| Patent application number | Description | Published |
|---|---|---|
| 20090288181 | Transgenic animals for analyzing CYP3A4 cytochrome P450 gene regulation - The invention relates to the generation of non-human transgenic animals comprising a reporter construct for producing a detectable amount of a reporter molecule operably linked to a transcriptional regulatory nucleic acid molecule from the human CYP3A4 gene located between the initiation of transcription site of the gene and a position located 13,000 nucleotides upstream from the site. The invention also relates to the use of these animals for determining the effect of a compound, particularly, but not exclusively, a xenobiotic or steroid, on the regulation of expression of the CYP3A4 gene in a human. | 11-19-2009 |
| 20090307785 | Transgenic animals for analyzing CYP3A4 cytochrome P450 gene regulation - The invention relates to the generation of non-human transgenic animals comprising a reporter construct for producing a detectable amount of a reporter molecule operably linked to a transcriptional regulatory nucleic acid molecule from the human CYP3A4 gene located between the initiation of transcription site of the gene and a position located 13,000 nucleotides upstream from the site. The invention also relates to the use of these animals for determining the effect of a compound, particularly, but not exclusively, a xenobiotic or steroid, on the regulation of expression of the CYP3A4 gene in a human. | 12-10-2009 |
| 20100146652 | XENOBIOTIC RELATED INDUCTION OF GENE EXPRESSION - An isolated nucleic acid molecule comprising a nucleotide sequence encoding a transcriptional enhancer of cytochrome P450 (P450) CYP3A4 production or expression, and uses of the nucleic acid molecule for screening compounds for xenobiotic induction of CYP3A4 expression in cells and animals. | 06-10-2010 |
| 20120171690 | Transgenic Animals for Analyzing CYP3A4 Cytochrome P450 Gene Regulation - The invention relates to the generation of non-human transgenic animals comprising a reporter construct for producing a detectable amount of a reporter molecule operably linked to a transcriptional regulatory nucleic acid molecule from the human CYP3A4 gene located between the initiation of transcription site of the gene and a position located 13,000 nucleotides upstream from the site. The invention also relates to the use of these animals for determining the effect of a compound, particularly, but not exclusively, a xenobiotic or steroid, on the regulation of expression of the CYP3A4 gene in a human. | 07-05-2012 |
Christopher Liddle, New South Wales AU
| Patent application number | Description | Published |
|---|---|---|
| 20090209500 | USE OF VITAMIN D RECEPTOR AGONISTS AND PRECURSORS TO TREAT FIBROSIS - This application relates to methods of treating, preventing, and ameliorating fibrosis, such as fibrosis of the liver, kidney, or pancreas. In particular, the application relates to methods of using a vitamin D receptor agonist (such as vitamin D, vitamin D analogs, vitamin D precursors, and vitamin D receptor agonists precursors) for the treatment of fibrosis. Also disclosed are methods for screening for agents that treat, prevent, and ameliorate fibrosis. | 08-20-2009 |
| 20110014126 | USE OF VITAMIN D RECEPTOR AGONISTS AND PRECURSORS TO TREAT FIBROSIS - This application relates to methods of treating, preventing, and ameliorating fibrosis, such as fibrosis of the liver. In particular, the application relates to methods of using a vitamin D receptor agonist (such as vitamin D, vitamin D analogs, vitamin D precursors, and vitamin D receptor agonists precursors) for the treatment of liver fibrosis. Also disclosed are methods for screening for agents that treat, prevent, and ameliorate fibrosis. | 01-20-2011 |
Gregory William Liddle, South Australia AU
| Patent application number | Description | Published |
|---|---|---|
| 20090009714 | Apparatus and Method For Assement and Rehabilitation After Acquired Brain Injury - The present invention relates to an apparatus and method for the assessment and rehabilitation of vision impairment. In particular, the invention is concerned with an apparatus displaying visual stimuli and the method of using this device for the purpose of assessment and rehabilitation of individuals with acquired brain injury and visual impairment resulting therefrom. The apparatus comprises a display means with a plurality of visual stimuli switched on and off in predetermined sequences. The sequences are adapted to be used to assess and rehabilitate a person's visual impairment. | 01-08-2009 |
Janette Liddle, Oak Grove, MN US
| Patent application number | Description | Published |
|---|---|---|
| 20130134195 | Handled tool holder - A device for storing handled tools in a vehicle, formed from a three dimensional body sized to fit in a vehicle and having a vertical dimension defining a vertical wall. The body includes at least one tube extending from the vertical wall of the body through at least a portion of the body, the at least one tube being sized to accommodate a handled tool. The body has a top surface on the body having sufficient strength to support cargo carried in the vehicle. | 05-30-2013 |
John Liddle, Stevenage GB
| Patent application number | Description | Published |
|---|---|---|
| 20090186867 | Substituted Diketopiperazines As Oxytocin Antagonists - A method of treating or preventing diseases or conditions mediated through the action of oxytocin which comprises administering to a human in need thereof of an effective amount of a compound of formula (I) or a pharmaceutically acceptable salt thereof. | 07-23-2009 |
| 20090247541 | Novel compounds - Compounds of formula (I) | 10-01-2009 |
| 20100305127 | NOVEL COMPOUNDS - Compounds of formula (I) | 12-02-2010 |
| 20110152262 | NOVEL COMPOUNDS - Compounds of formula (I) | 06-23-2011 |
| 20120004229 | SUBSTITUTED DIKETOPIPERAZINES AND THEIR USE AS OXYTOCIN ANTAGONISTS - Compounds of formula (1) | 01-05-2012 |
| 20120202811 | NOVEL COMPOUNDS - Compounds of formula (I) | 08-09-2012 |
| 20120232061 | NOVEL COMPOUNDS - A compound of formula (I): | 09-13-2012 |
| 20130040984 | 7-(lH-PYRAZOL-4-YL)-1,6-NAPHTHYRIDINE COMPOUNDS AS SYK INHIBITORS - The present invention relates to a compound of formula (I): | 02-14-2013 |
John Liddle, Hertfordshire GB
| Patent application number | Description | Published |
|---|---|---|
| 20080242666 | 1-6-Substituted (3R,6R)-3-(2,3-Dihydro-1H-Inden-2-Yl)-2,5-Piperazinedione Derivatives as Oxytocin Receptor Antagonists For the Treatment of Preterm Labour, Dysmenorrhea and Endometriosis - The present invention relates to Compound S of Formula (I). | 10-02-2008 |
| 20100035917 | PYRROLO[2,3-B]PYRIDIN-4-YL-BENZENESULFONAMIDE COMPOUNDS AS 1KK2 INHIBITORS - The invention is directed to certain novel compounds. Specifically, the invention is directed to compounds according to Formula (1) and salts thereof. The compounds of the invention are inhibitors of kinase activity, in particular 1KK2 activity. | 02-11-2010 |
| 20100179128 | XANTHINE DERIVATIVES AS SELECTIVE HM74A AGONISTS - The present invention relates to compounds of formula (I) which are xanthine derivatives, processes for the manufacture of said derivatives, pharmaceutical formulations containing these active compounds and the use of the compounds in therapy, for example, in the treatment of diseases where under-activation of the HM74A receptor contributes to the disease or where activation of the receptor will be beneficial | 07-15-2010 |
| 20100179139 | PYRROLOPYRIDINE COMPOUNDS, PROCESS FOR THEIR PREPARATION, AND THEIR USE AS MEDICAMENTS - The invention is directed to certain novel compounds. Specifically, the invention is directed to compounds according to formula (I): | 07-15-2010 |
John W. Liddle, Imperial, PA US
| Patent application number | Description | Published |
|---|---|---|
| 20080207787 | Rigid polyurethane foams with increased heat performance - The present invention provides a rigid polyurethane foam made from the reaction product, at an isocyanate index of from about 90 to about 400, of a polyisocyanate, and a polyol component containing about 20 to about 80 wt. %, based on the weight of the polyol component, of a double metal cyanide (DMC)-catalyzed polyether polyol having a number average molecular weight of greater than about 1000 Daltons (Da), about 80 to about 20 wt. %, based on the weight of the polyol component, of a sucrose-based polyol having a functionality of from about 2.5 to about 6 and a molecular weight of from about 350 to less than about 1,000, and about 0 to about 40 wt. %, based on the weight of the polyol component, of a low molecular weight organic compound having a number average molecular weight of less than about 600 Da, in the presence of water, polyvinylchloride (PVC) particles having a diameter of from about 0.1 to about 200 microns, and glass beads having a diameter of from about 40 to about 400 microns (about 270 to about 45 mesh), and optionally, in the presence of at least one of carbon dioxide, surfactants, flame retardants, pigments and catalysts, wherein the rigid polyurethane foam with a density of about 10 to about 25 pcf has a heat sag measured at 102 mm overhang at 121° C. and one hour of less than about 8 mm. The inventive rigid polyurethane foams exhibit increased heat performance (decreased heat sag) while also maintaining impact and rebound strengths. | 08-28-2008 |
Kerry Liddle, Oak Grove, MN US
| Patent application number | Description | Published |
|---|---|---|
| 20130134195 | Handled tool holder - A device for storing handled tools in a vehicle, formed from a three dimensional body sized to fit in a vehicle and having a vertical dimension defining a vertical wall. The body includes at least one tube extending from the vertical wall of the body through at least a portion of the body, the at least one tube being sized to accommodate a handled tool. The body has a top surface on the body having sufficient strength to support cargo carried in the vehicle. | 05-30-2013 |
Mark Liddle, Binfield GB
| Patent application number | Description | Published |
|---|---|---|
| 20120322558 | Control Unit For A Video Games Console Provided With A Tactile Screen - A control unit for a home video game console, including a control unit body, a display supported by the control unit body for displaying information and/or images relating to the game, and a recess defined by the control unit body for accommodating a second control unit equipped with an accelerometer and/or with tilt sensors. The recess has an electrical connection between the two control units, wherein the displayed information and/or images are changed in response to signals received by the accelerometer and/or the tilt sensors and transmitted to the display through the electrical connection. A touch screen overlying at least partially over the display, detects tactile commands including a sequence of locations touched on the screen able to change the displayed information and/or images. | 12-20-2012 |
Raymond John Liddle, South Australia AU
| Patent application number | Description | Published |
|---|---|---|
| 20090009714 | Apparatus and Method For Assement and Rehabilitation After Acquired Brain Injury - The present invention relates to an apparatus and method for the assessment and rehabilitation of vision impairment. In particular, the invention is concerned with an apparatus displaying visual stimuli and the method of using this device for the purpose of assessment and rehabilitation of individuals with acquired brain injury and visual impairment resulting therefrom. The apparatus comprises a display means with a plurality of visual stimuli switched on and off in predetermined sequences. The sequences are adapted to be used to assess and rehabilitate a person's visual impairment. | 01-08-2009 |
Rodger Liddle, Durham, NC US
| Patent application number | Description | Published |
|---|---|---|
| 20090221872 | Endoscope Tip Protector - The invention provides an endoscope tip protector for protecting the distal tip of an endoscope and an endoscope assembly including the tip protector affixed thereto. The endoscope tip protector can include a main body with an opening through the main body sized to accept an endoscope sheath and a white surface arranged to face a distal end of an endoscope sheath when the sheath is placed in the endoscope tip protector. Methods of making and using the tip protector and assembly are also provided. | 09-03-2009 |
Stephen Liddle, Orem, UT US
| Patent application number | Description | Published |
|---|---|---|
| 20100017287 | Method and System for Dynamic Advertising - A system and methods for advertising to targeted candidates and optimizing the advertisements to improve candidate response. The method and system enable an entity to advertise a need of an entity to a targeted group of candidates. After information about the need is received and the candidate target group is identified, the information is converted into a plurality of advertisements and distributed to a plurality of publishers that are within the candidate target group. The advertisements are displayed to candidates when they access at least one of the plurality of publishers. The advertisements are optimized to improve the response of the candidate target group by adjusting at least one manual control on a computer-network interface. | 01-21-2010 |
Stephen W. Liddle, Orem, UT US
| Patent application number | Description | Published |
|---|---|---|
| 20100114902 | HIDDEN-WEB TABLE INTERPRETATION, CONCEPTULIZATION AND SEMANTIC ANNOTATION - Indexing hidden web information. First and second web pages are accessed, which include data organized in table format. The tables from the first and second web page are compared. Based on the comparison, a determination is made as to which table cells contain category labels and which contain instance data. The category labels from the first web page are compared to the category labels from the second web page. A general structure of individual tables is inferred based on the act of comparing the category labels. The general structure is chosen from among standard table templates. Data in two or more web pages organized according to the selected table templates is identified. Data from the two or more web pages is stored by associating the table data from two or more web pages to one or more of the selected table templates. | 05-06-2010 |
| 20100115436 | FORM-BASED ONTOLOGY CREATION AND INFORMATION HARVESTING - Extracting data from web pages. User input is received defining a tabular form. User input is received correlating portions of the form with user selected data items contained in one or more first web pages. The user input is correlated to create an ontology defining relationships between the user selected data items based on the definition of the tabular form. One or more other web pages are accessed, and based on a context of the one or more data items in the first web page being similar to a context of the selected data items in the one or more first web pages, one or more similar data items are extracted from the one or more other web pages. The extracted data items are correlated to each other in accordance with the ontology defining relationships between the user selected data items and are output as a user searchable data structure. | 05-06-2010 |