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Liang, NJ

Bitao Liang, Closter, NJ US

Patent application numberDescriptionPublished
20110311491TREATMENT OF SARCOIDOSIS USING PLACENTAL STEM CELLS - Provided herein are compositions and methods of treating individuals having sarcoidosis or a sarcoidosis-related disease or disorder, using placental cells, e.g., the placental stem cells and placental multipotent cells (PDACs) described herein. Also provided herein are kits comprising said cells or a composition thereof.12-22-2011

Bo Liang, East Brunswick, NJ US

Patent application numberDescriptionPublished
20090263345Otic compositions for the treatment of infections of the internal and external ear in mammals - Disclosed herein compositions including povidone-iodine (PVP-I) useful in the treatment of acute and chronic bacterial, viral and fungal infections of the internal, middle and external ear of mammals, including humans.10-22-2009
20100197562FUNCTIONALLY SELECTIVE ALPHA2C ADRENORECEPTOR AGONISTS - In its many embodiments, the present invention provides a novel class of biaryl compounds as inhibitors of ÿ2C adrenergic receptor agonists, methods of preparing such compounds, pharmaceutical compositions containing one or more such compounds, methods of preparing pharmaceutical formulations comprising one or more such compounds, and methods of treatment, prevention, inhibition, or amelioration of one or more conditions associated with the ÿ2C adrenergic receptors using such compounds or pharmaceutical compositions.08-05-2010
20100254934Ophthalmic Compositions Comprising Povidone-Iodine - A topical ophthalmic composition comprised of povidone-iodine 0.01% to 10.0% combined with a steroid or non-steroidal anti-inflammatory drug. This solution is useful in the treatment of active infections of at least one tissue of the eye (e.g., conjunctiva and cornea) from bacterial, mycobacterial, viral, fungal, or amoebic causes, as well as treatment to prevent such infections in appropriate clinical settings (e.g. corneal abrasion, postoperative prophylaxis, post-LASIK/LASEK prophylaxis). Additionally the solution is effective in the prevention of infection and inflammation in the post-operative ophthalmic patient.10-07-2010
20100291019Methods of Using Ophthalmic Compositions Comprising Povidone-Iodine - A topical ophthalmic composition comprised of povidone-iodine 0.01% to 10.0% combined with a steroid or non-steroidal anti-inflammatory drug. This solution is useful in the treatment of active infections of at least one tissue of the eye (e.g., conjunctiva and cornea) from bacterial, mycobacterial, viral, fungal, or amoebic causes, as well as treatment to prevent such infections in appropriate clinical settings (e.g. corneal abrasion, postoperative prophylaxis, post-LASIK/LASEK prophylaxis). Additionally the solution is effective in the prevention of infection and inflammation in the post-operative ophthalmic patient.11-18-2010

Bo Liang, Lawrenceville, NJ US

Patent application numberDescriptionPublished
20100173823ALPHA2C ADRENORECEPTOR AGONISTS - In its many embodiments, the present invention relates to a novel class of phenylmorpholine and phenylthiomorpholine compounds useful as α2C adrenergic receptor agonists, pharmaceutical compositions containing the compounds, and methods of treatment, prevention, inhibition, or amelioration of one or more diseases associated with the α2C adrenergic receptor agonists using such compounds or pharmaceutical compositions.07-08-2010

Patent applications by Bo Liang, Lawrenceville, NJ US

Gui-Bai Liang, Scotch Plains, NJ US

Patent application numberDescriptionPublished
20100216694ANTIDIABETIC TRICYCLIC COMPOUNDS - Tricyclic compounds containing a cyclopropanecarboxylic acid fused to a bicyclic ring, including pharmaceutically acceptable salts, are agonists of G-protein coupled receptor 40 (GPR40) and are useful as therapeutic compounds, particularly in the treatment of Type 2 diabetes, and of conditions that are often associated with this disease, including obesity and lipid disorders, such as mixed or diabetic dyslipidemia, hyperlipidemia, hypercholesterolemia, and hypertriglyceridemia.08-26-2010
20110207737SUBSTITUTED BICYCLIC AMINES FOR THE TREATMENT OF DIABETES - Described herein are substituted bicyclic amines. In particular, described herein are substituted bicyclic amines that are effective as antagonists of SSTR5 and useful for the treatment, control or prevention of disorders responsive to antagonism of SSTR5, such as type 2 diabetes, insulin resistance, lipid disorders, obesity, atherosclerosis, metabolic syndrome, depression, and anxiety.08-25-2011

Patent applications by Gui-Bai Liang, Scotch Plains, NJ US

Guyan Liang, Warren, NJ US

Patent application numberDescriptionPublished
20100028895METHOD FOR DETERMINING THE STABILITY OF ORGANIC METHYLENEAMINES IN THE PRESENCE OF SEMICARBAZIDE-SENSITIVE AMINE OXIDASE - The present invention provides methods for determining the stability of methyleneamine, methyleneamine-like compounds or compounds containing an methyleneamine moiety in the presence of semicarbazide-sensitive amine oxidase (SSAO) or a biological sample containing SSAO activity. The disclosed methods may be configured in an assay format for high throughput screening applications.02-04-2010

Jennifer Q. Liang, Morris Plains, NJ US

Patent application numberDescriptionPublished
20080312306POLYMORPHS, SOLVATES, AND HYDRATE OF 5-(4'-FLUORO-2'-OXO-1',2'-DIHYDROSPIRO[CYCLOPROPANE-1,3'-INDOL]-5'-YL)-1-METHYL-1H-PYRROLE-2-CARBONITRILE - Novel polymorph Form II and III, solvate Forms I, II, III, and IV, and the hydrate of 5-(4′-fluoro-2′-oxo-1′,2′-dihydrospiro[cyclopropane-1,3′-indol]-5′-yl)-1-methyl-1H-pyrrole-2-carbonitrile are provided, as are methods for preparing the same. Pharmaceutical compositions and kits containing these novel polymorphs, solvates, and hydrate, and combinations thereof are further provided, as are methods of contraception; treating or preventing fibroids, uterine leiomyomata, endometriosis, dysfunctional bleeding, polycystic ovary syndrome, hormone-dependent carcinomas; treating symptoms of premenstrual syndrome and premenstrual dysphoric disorder; providing hormone replacement therapy; stimulating food intake; synchronizing estrus; or treating symptoms of premenstrual syndrome using one or more of these polymorphs, solvates, or hydrate.12-18-2008

Jennifer Qianying Liang, Morris Plains, NJ US

Patent application numberDescriptionPublished
20100216886POLYMORPHS OF N2-(1,1'-BIPHENYL-4-YLCARBONYL)-N1-[2-(4-FLUOROPHENYL)-1,1-DIMETHYLETHYL]- -L-ALPHA-GLUTAMINE - Disclosed are novel polymorphic forms of N08-26-2010

Jessica Liang, Annandale, NJ US

Patent application numberDescriptionPublished
20100197705Quinazolinone Derivatives Useful as Vanilloid Antagonists - There is described a new polymorphic form of 4-(7-Hydroxy-2-isopropyl-4-oxo-4H-quinazolin-3-yl)-benzonitrile having structural formula I(B) and to a method of preparing it.08-05-2010
20110171159Glycoside Derivatives and Uses Thereof - This invention relates to compounds represented by formula (I):07-14-2011

Jinjun Liang, Princeton, NJ US

Patent application numberDescriptionPublished
20080293583Methods for diagnosing mood disorders - The present invention relates generally to the fields of neuroscience, proteomics and mood disorders. More particularly, the present invention relates to the identification of a group of proteins modulated in subjects with a mood disorder; methods for detecting or screening mRNA encoding these proteins and methods for diagnosing mood disorders.11-27-2008

Luke Liang, Plainfield, NJ US

Patent application numberDescriptionPublished
20090077897Casement window hinge - A hinge for casement windows is disclosed. The said hinge includes a track and a shoe that is adapted to travel along the track. There is a sash arm that is pivotally connected and extending from the shoe and a support arm. The support arm has a first end and a second end. The first end is pivotally connected to the sash arm and said second end of the support arm is pivotally connected to the track. The support arm has an orifice for receiving a pin extending from the track. The support arm has a clip for securing the support arm to the track. The clip has a grip extending therefrom to assist in moving the clip from a first position to a second position.03-26-2009

Luke Liang, S. Plainfield, NJ US

Patent application numberDescriptionPublished
20100313488Adjustable after-market sash window stop - An adjustable stop is adapted to limit travel of a sliding sash window/door, and can be installed upon the window/door master frame during initial manufacturing of the product, or may be an after-market option added at some time after manufacturing was completed. The stop may even be installed upon sash windows/doors currently in service in a building. The stop is intended to limit sash travel between a closed position and a safe position, where the safe position is a position significantly less than a full-open position. The safety stop may be comprised of a housing and a tumbler being pivotally mounted within a cavity in the housing, with a spring to bias the tumbler out of an opening in the housing. Mounting is by a flange extending from the housing, with spacers of varying thickness that are capable of removably attaching thereon to accommodate sash to master frame height differences.12-16-2010

Luke Liang, Irvington, NJ US

Patent application numberDescriptionPublished
20100192643Window sash latch - An improved window sash latch which has a locking mechanism and a keeper is provided with a handle that rotates from a “locked” to an “unlocked” position. An inner cavity of the handle has a spring assembly having a sliding part that can be forced into a detent as the handle slides around a cylindrical extension of an outer surface of the latch. The detents correspond to a “locked” and an “unlocked” position of the latch. The latch also provides two cams where both cams revolve relative to each other; one cam is activated by the handle through the handle's shaft, the other cam engages the keeper, and both cams engage each other.08-05-2010

Patent applications by Luke Liang, Irvington, NJ US

Luke Liang, So. Plainfield, NJ US

Patent application numberDescriptionPublished
20100019513Window lock keeper - An improved sash lock and keeper for a sash window assembly is disclosed. The sash window includes an upper sash window and a lower sash window. Each of the sashes is mounted within opposed guide rails which permit at least one of the sashes to travel slidably therein.01-28-2010
20110248516Sash lock with signal - A sash lock comprises a housing, latch member, activator arm, and trigger. The latch member is spring biased to slide from an unlocked position towards a locked position. The activator arm and trigger are pivotally mounted within the housing, with a torsion spring biasing the trigger relative to the activator arm, to cause the activator arm to pivot and contact the latch member. When the latch member is moved to the unlocked position, the biased activator arm engages the latch member to retain it in the unlocked position, while the biased trigger member pivots to have a portion protrude out of the housing. Upon closing the sash member, an angled surface of a keeper contacts a curved surface of the protruding trigger to cause it to counter-rotate and drive the activator arm to disengage from the latch member and automatically permit biasing of the latch member into the locked position.10-13-2011

Patent applications by Luke Liang, So. Plainfield, NJ US

Pearl Liang, Kearny, NJ US

Patent application numberDescriptionPublished
20090023563BODY TONE EXERCISE BRICKS - A body tone exercise brick includes a brick body having a receiving chamber opened upward, a bar detachably mounted in the receiving chamber of the brick body, and a pair of weight members alternatively placed in the receiving chamber of the brick body or detachably coupled to two ends of the bar when the bar is taken out from the receiving chamber of the brick body. Thus, the body tone exercise brick of the invention has a variety of exercise modes to train muscles of various portions.01-22-2009
20090023565VIBRA BACK WAVE - A back stretching device includes a curved cushion having an elongated slot through top and bottom sides thereof, a housing mounted on the bottom side of the curved cushion, a motor mounted in the housing, and a rotating member accommodated in the housing and eccentrically connected with an output shaft of the motor. Thus, the back stretching device of the invention can be used to effectively stretch and relax a user's back muscles.01-22-2009

Ray-Hung Liang, Morris Plains, NJ US

Patent application numberDescriptionPublished
20090066088Vertical axis wind turbine - One aspect of the present invention relates to a vertical axis wind turbine. In one embodiment, the vertical axis wind turbine comprises a rotor comprising a vertical oriented shaft, and a plurality of vertical oriented blades angle-equally and radially secured to the vertical aligned shaft. Each of the plurality of vertical oriented blades has a face side, a back side, at least one window and at least one pane pivotally mounted onto the at least one window on the face side such that the at least one pane is rotatable between a closed position and an opening position around a pivotal axis responsive to a wind condition thereof. The pivotal axis is substantially perpendicular to the vertical oriented shaft.03-12-2009

Rui Liang, East Brunswick, NJ US

Patent application numberDescriptionPublished
20090054423Niacin receptor agonists, compositions containing such compounds and methods of treatment - The present invention encompasses compounds of Formula I: as well as pharmaceutically acceptable salts and hydrates thereof, that are useful for treating dyslipidemias. Pharmaceutical compositions and methods of use are also included.02-26-2009
20090054506Glucagon receptor antagonist compounds, compositions containing such compounds and methods of use - Substituted aryl and heteroaryl derivatives are disclosed. The compounds are useful for treating type 2 diabetes and related conditions. Pharmaceutical compositions and methods of treatment are also included.02-26-2009
20090176854PYRAZOLE DERIVATIVES, COMPOSITIONS CONTAINING SUCH COMPOUNDS AND METHODS OF USE - Pyrazoles having a naphthyl group attached are disclosed. The compounds are useful for treating type 2 diabetes and related conditions. Pharmaceutical compositions and methods of treatment are also included.07-09-2009
20110039860SOLUBLE EPOXIDE HYDROLASE INHIBITORS, COMPOSITIONS CONTAINING SUCH COMPOUNDS AND METHODS OF TREATMENT - Compounds of the formula (I) or a pharmaceutically acceptable salt or solvate thereof is disclosed. The compounds are useful for treating diabetes, inflammation, atherosclerosis, hypertension, pain and the like. Pharmaceutical compositions and methods of use are also included.02-17-2011
20110172256GLUCAGON RECEPTOR ANTAGONIST COMPOUNDS, COMPOSITIONS CONTAINING SUCH COMPOUNDS AND METHODS OF USE - Glucagon receptor antagonist compounds are disclosed. The compounds are useful for treating type 2 diabetes and related conditions. Pharmaceutical compositions and methods of treatment are also included.07-14-2011

Patent applications by Rui Liang, East Brunswick, NJ US

Xian Liang, Monmouth Junction, NJ US

Patent application numberDescriptionPublished
20110124867Process and intermediates for the Synthesis of heterocyclic Substituted Piperazines with CXCR3 Antagonist Activity - The present invention relates to novel processes for the preparation of the compound of the Formula A45:05-26-2011
20110236400TETRAHYDROPYRANOCHROMENE GAMMA SECRETASE INHIBITORS - Disclosed are novel gamma secretase inhibitors of the formula. Also disclosed are methods of inhibiting gamma-secretase, methods of treating neurodegenerative diseases, and methods of treating Alzheimer's Disease. Also disclosed are processes for preparing alkenes in one reaction step using a mixture of an aldehyde (or ketone) and an alkyl substituted with two electron withdrawing groups, and reacting the mixture with: (a) a sulfonyl halide (e.g., a sulfonyl chloride) and a basic tertiary amine, or, (b) a sulfonyl anhydride and a basic amine, or (c) an aryl-C(O)-halide and a basic tertiary amine, or (d) an aryl-C(O)—O—C(O)-aryl and a basic tertiary amine, or (e) an heteroaryl-C(O)-halide and a basic tertiary amine, or (f) a heteroaryl-C(O)—O—C(O)-heteroaryl and a basic tertiary amine.09-29-2011

Xiaogan Liang, Plainsboro, NJ US

Patent application numberDescriptionPublished
20080217822METHOD AND APPARATUS OF ELECTRICAL FIELD ASSISTED IMPRINTING - A method and apparatus for performing nanoimprint lithography. When an electric field is applied between the mold and the substrate, various forces can be generated among molds, substrates, and resists. The electrostatic force between the mold and the substrate can serve as an imprinting pressure to press the structured mold into the conformable resist. In addition, the electric field induces additional wetting forces (electrowetting or dielectrophoresis) in a liquid resist, which can assist the flow and filling of the liquid resist into fine structures.09-11-2008
20100009541Process for Adjusting the Size and Shape of Nanostructures - In accordance with the invention, a lateral dimension of a microscale device on a substrate is reduced or adjusted by the steps of providing the device with a soft or softened exposed surface; placing a guiding plate adjacent the soft or softened exposed surface; and pressing the guiding plate onto the exposed surface. Under pressure, the soft material flows laterally between the guiding plate and the substrate. Such pressure induced flow can reduce the lateral dimension of line spacing or the size of holes and increase the size of mesas. The same process also can repair defects such as line edge roughness and sloped sidewalls. This process will be referred to herein as pressed self-perfection by liquefaction or P-SPEL.01-14-2010
20100081282PROCESS FOR ADJUSTING THE SIZE AND SHAPE OF NANOSTRUCTURES - In accordance with the invention, a lateral dimension of a microscale device on a substrate is reduced or adjusted by the steps of providing the device with a soft or softened exposed surface; placing a guiding plate adjacent the soft or softened exposed surface; and pressing the guiding plate onto the exposed surface. Under pressure, the soft material flows laterally between the guiding plate and the substrate. Such pressure induced flow can reduce the lateral dimension of line spacing or the size of holes and increase the size of mesas. The same process also can repair defects such as line edge roughness and sloped sidewalls. This process will be referred to herein as pressed self-perfection by liquefaction or P-SPEL.04-01-2010

Xiaogan Liang, Princeton, NJ US

Patent application numberDescriptionPublished
20090115094METHODS FOR MAKING CONTINUOUS NANOCHANNELS - This application describes a novel method of fabricating narrow (2-100 nm) width and long (greater than 50 micrometers and preferably 1 centimeter or longer) yet continuous hollow channels that allow flow of fluid or gas, or their combination. It can optimally include RIE pattern transfer or an optional sealing of a top surface over the channel. The invention also includes a novel method for making an imprint mold for imprinting the channel.05-07-2009
20100267158Electronic Detectors Inside Nanofluidic Channels For Detection, Analysis, and Manipulation of Molecules, Small Particles, and Small Samples of Material - The present invention provides methods and apparatus that can manipulate, detect, and/or analyze single molecules, single small particles or single small samples of matter passing through a nanoscale gap within a nanofluidic channel of a detector.10-21-2010

Yixing Liang, Princeton, NJ US

Patent application numberDescriptionPublished
20100009541Process for Adjusting the Size and Shape of Nanostructures - In accordance with the invention, a lateral dimension of a microscale device on a substrate is reduced or adjusted by the steps of providing the device with a soft or softened exposed surface; placing a guiding plate adjacent the soft or softened exposed surface; and pressing the guiding plate onto the exposed surface. Under pressure, the soft material flows laterally between the guiding plate and the substrate. Such pressure induced flow can reduce the lateral dimension of line spacing or the size of holes and increase the size of mesas. The same process also can repair defects such as line edge roughness and sloped sidewalls. This process will be referred to herein as pressed self-perfection by liquefaction or P-SPEL.01-14-2010
20100081282PROCESS FOR ADJUSTING THE SIZE AND SHAPE OF NANOSTRUCTURES - In accordance with the invention, a lateral dimension of a microscale device on a substrate is reduced or adjusted by the steps of providing the device with a soft or softened exposed surface; placing a guiding plate adjacent the soft or softened exposed surface; and pressing the guiding plate onto the exposed surface. Under pressure, the soft material flows laterally between the guiding plate and the substrate. Such pressure induced flow can reduce the lateral dimension of line spacing or the size of holes and increase the size of mesas. The same process also can repair defects such as line edge roughness and sloped sidewalls. This process will be referred to herein as pressed self-perfection by liquefaction or P-SPEL.04-01-2010

Yufeng Liang, West Windsor, NJ US

Patent application numberDescriptionPublished
20100287062Method and Apparatus for Facilitating Buyer Driven Transaction - A method and apparatus for facilitating a buyer driven transaction are provided. The method comprises the steps of registering a seller to receive one or more conditional purchase offers, the seller agreeing to one or more terms to be employed upon entry into a transaction with a buyer upon acceptance of one of the one or more conditional purchase offers, and registering a buyer to submit one or more conditional purchase offers, the buyer agreeing to one or more terms to be employed upon entry into a transaction with the seller upon acceptance of one of the one or more conditional purchase offers. A conditional purchase offer is received from the buyer for a particular defined product, the conditional purchase offer including at least one or more product indicators, a price offer, and an offer expiration. The submitted conditional purchase offer is provided to the seller associated with the particular defined product. The seller is able to bind the buyer to purchase the particular defined product in accordance with the terms set forth in the conditional purchase offer and the agreed upon terms, and also to bind the seller to sell the particular defined product in accordance with the terms set forth in the conditional purchase offer and the agreed upon terms upon acceptance of the conditional purchase offer by the seller.11-11-2010