Li, Andover
Hongxing Li, Andover, MA US
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20160134301 | DELTA-SIGMA MODULATOR HAVING TRANSCONDUCTOR NETWORK FOR DYNAMICALLY TUNING LOOP FILTER COEFFICIENTS - A dynamically tunable transconductor includes a voltage-to-current converter stage for generating a current signal based on a voltage signal; and a current scaling stage for scaling the current signal by a scaling factor to achieve a particular transconductance. Current scaling stage includes a coarse tune mechanism having an associated coarse tune step and a fine tune mechanism having an associated fine tune step, where the scaling factor is a ratio of the coarse tune step to the fine tune step. A delta-sigma modulator can implement the transconductor to generate loop filter coefficients by dynamically tuning the transconductance to achieve a particular resistance. | 05-12-2016 |
Kewen Kevin Li, Andover, MA US
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20090168150 | ELECTRO-OPTIC GAIN CERAMIC AND LOSSLESS DEVICES - The present invention provides a neodymium doped, transparent electro-optic gain ceramic material consisting lead, zirconium, titanium and lanthanum. The electro-optic gain ceramic material either has a linear electro-optic coefficient or a quadratic electro-optic coefficient, which is greater than about 0.3×10 | 07-02-2009 |
Peter Li, Andover, MA US
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20080219892 | Guided Mode Resonant Filter Biosensor Using a Linear Grating Surface Structure - Methods and compositions are provided for detecting biomolecular interactions. The use of labels is not required and the methods can be performed in a high-throughput manner. The invention also provides optical devices useful as narrow band filters. | 09-11-2008 |
20090148955 | Label-Free High-Throughput Optical Technique for Detecting Biomolecular Interactions - Methods and compositions are provided for detecting biomolecular interactions. The use of labels is not required and the methods can be performed in a high-throughput manner. The invention also provides optical devices useful as narrow band filters. | 06-11-2009 |
20090264314 | Optical Detection of Label-Free Biomolecular Interactions Using Microreplicated Plastic Sensor Elements - Methods and compositions are provided for detecting biomolecular interactions. The use of labels is not required and the methods can be performed in a high-throughput manner. The invention also provides optical devices useful as narrow band filters. | 10-22-2009 |
20100196925 | Methods for Screening Cells and Antibodies - The invention provides methods of detecting a change in cell growth patterns, methods of screening many different antibodies in one receptacle, and methods of detecting specific binding of an antibody to a protein or cell, wherein the antibody is in a mixture of many different antibodies. | 08-05-2010 |
20100231907 | Method and Apparatus for Biosensor Spectral Shift Detection - Performing high-resolution determination of the relative shift of the spectral properties of a biosensor. The shift in the resonance peak of the biosensor is indicative of the amount of material bound to the surface of the biosensor. A preferred biosensor is a Guided Mode Resonant Filter Biosensor (GMRFB). In one aspect of the invention, curve fitting is used to determine the relative location of the spectrum of the unexposed biosensor with respect to those spectra that are altered (e.g., shifted) by the presence of materials bound to the surface of the biosensor. In an alternative embodiment, the cross correlation function is used to detect spectral peak offsets between a reference spectrum and a spectrum measured from an exposed biosensor. In yet another alternative, maximal likelihood estimation techniques are used to determine the spectral shift or offs. | 09-16-2010 |
20110201132 | Optical Detection of Label-Free Biomolecular Interactions using Microreplicated Plastic - Methods and compositions are provided for detecting biomolecular interactions. The use of labels is not required and the methods can be performed in a high-throughput manner. The invention also provides optical devices useful as narrow band filters. | 08-18-2011 |
20110237464 | Guided Mode Resonant Filter Biosensor Using a Linear Grating Surface Structure - Methods and compositions are provided for detecting biomolecular interactions. The use of labels is not required and the methods can be performed in a high-throughput manner. The invention also provides optical devices useful as narrow band filters. | 09-29-2011 |
20130130926 | Methods for Screening Cells and Antibodies - The invention provides methods of detecting a change in cell growth patterns, methods of screening many different antibodies in one receptacle, and methods of detecting specific binding of an antibody to a protein or cell, wherein the antibody is in a mixture of many different antibodies. | 05-23-2013 |
20130336567 | INTERNAL FOCUS REFERENCE BEADS FOR IMAGING CYTOMETRY - The invention generally relates to analytical and monitoring systems useful for analyzing and measuring cells and biological samples. More particularly, the invention provides systems and methods for internal calibration and focus reference for cytometry imaging. | 12-19-2013 |
20150232906 | AUTOMATED YEAST BUDDING MEASUREMENT - The invention generally relates to analyzing yeast viability and reproduction rate of yeasts. More particularly, the invention relates to efficient and effective methods and compositions for accessing and measuring budding percentages, viability and concentration of yeast cells. | 08-20-2015 |
20160025710 | INTERNAL FOCUS REFERENCE BEADS FOR IMAGING CYTOMETRY - The invention generally relates to analytical and monitoring systems useful for analyzing and measuring cells and biological samples. More particularly, the invention provides systems and methods for internal calibration and focus reference for cytometry imaging. | 01-28-2016 |
Wei Li, Andover, MA US
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20130057998 | SYSTEMS AND METHODS FOR SWITCHING A RELAY AT ZERO CROSS - Circuitry, systems and methods that address the need to coordinate relay switching with another event, such as a zero crossing of an alternating current (AC) voltage waveform are described. In some embodiments, the systems and methods continuously or periodically calibrate the timing of control signals to a relay, such that the switching of the relay in response to some (e.g., second or subsequent) control signals occurs closer in time to a zero crossing of an AC line voltage than the switching of the relay in response to other (e.g., initial or first) control signals. | 03-07-2013 |
Xiang-Yi Li, Andover, MA US
Patent application number | Description | Published |
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20090082313 | Multikinase Inhibitors for Use in the Treatment of Cancer - The present invention provides compounds, pharmaceutical compositions and methods for the treatment of specific cancers. Such compositions may generally comprise a compound of formula (I): | 03-26-2009 |
20090197867 | ENANTIOMERICALLY ENRICHED IMIDAZOAZEPINONE COMPOUNDS - The present invention provides an enantiomerically pure compound of Formula I: | 08-06-2009 |
20090291998 | EPONEMYCIN AND EPOXOMICIN ANALOGS AND USES THEREOF - The present invention provides compounds having formula (1): wherein R | 11-26-2009 |
20100093842 | Laulimalide Analogs and Uses Thereof - The present invention provides compounds having formula I: | 04-15-2010 |
20110105427 | DEAZAPURINES AND USES THEREOF - The present invention provides compounds having formula (I): | 05-05-2011 |
20110144101 | MACROCYCLIC COMPOUNDS USEFUL AS PHARMACEUTICALS - The present invention provides methods for the use of compounds having formula (I) in the treatment of various disorders including inflammatory or autoimmune disorders, and disorders involving malignancy or increased angiogenesis, wherein R | 06-16-2011 |
20130196987 | MACROCYCLIC COMPOUNDS USEFUL AS PHARMACEUTICALS - The present invention provides compounds, methods for the synthesis thereof and methods for the use thereof in the treatment of various disorders including inflammatory or autoimmune disorders, and disorders involving malignancy or increased angiogenesis. | 08-01-2013 |
20130303489 | MULTIKINASE INHIBITORS FOR USE IN THE TREATMENT OF CANCER - The present invention provides compounds, pharmaceutical compositions and methods for the treatment of specific cancers. Such compositions may generally comprise a compound of formula (I): | 11-14-2013 |
20150182496 | MULTIKINASE INHIBITORS FOR USE IN THE TREATMENT OF CANCER - The present invention provides compounds, pharmaceutical compositions and methods for the treatment of specific cancers. Such compositions may generally comprise a compound of formula (I): | 07-02-2015 |
Yunchu Li, Andover, MA US
Patent application number | Description | Published |
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20080224908 | Mixer/DAC Chip and Method - An electronic chip has a data input for receiving an input digital data signal with a data frequency, a plurality of switches, and a logic circuit operatively coupled with both the plurality of switches and the data input. The logic circuit controls the switches to be in one of a DAC mode or a mixer mode. The DAC mode causes the switches to convert the input digital data signal into a DAC analog signal having about the data frequency. The mixer mode, however, causes the switches to convert the input digital data signal into a mixed analog signal having a mixer frequency that is higher than the data frequency. | 09-18-2008 |
20100301913 | CMOS Clock Receiver with Feedback Loop Error Corrections - A system for correcting duty cycle errors in a clock receiver that includes a differential amplifier having inputs for a pair of differential clock signals. A duty cycle error detector has inputs for a pair of amplified clock signals and an output for a duty cycle error correction signal. A signal conditioner is also provided with the differential amplifier having an input for the duty cycle error correction signal. Furthermore, the signal conditioner adjusts the differential clock signals in response to the duty cycle error correction signal. Also, a system for correcting cross point errors in a clock receiver that includes a differential amplifier having inputs for a pair of differential clock signal. A cross point error detector has inputs for a pair of amplified clock signals and an output for a cross point error correction signal. A signal conditioner is also provided with the differential amplifier having an input for the cross point error correction signal. Furthermore, the signal conditioner adjusts the differential clock signals in response to the cross point error correction signal. | 12-02-2010 |