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Li, Andover

Kewen Kevin Li, Andover, MA US

Patent application numberDescriptionPublished
20090168150ELECTRO-OPTIC GAIN CERAMIC AND LOSSLESS DEVICES - The present invention provides a neodymium doped, transparent electro-optic gain ceramic material consisting lead, zirconium, titanium and lanthanum. The electro-optic gain ceramic material either has a linear electro-optic coefficient or a quadratic electro-optic coefficient, which is greater than about 0.3×1007-02-2009

Patent applications by Kewen Kevin Li, Andover, MA US

Peter Li, Andover, MA US

Patent application numberDescriptionPublished
20080219892Guided Mode Resonant Filter Biosensor Using a Linear Grating Surface Structure - Methods and compositions are provided for detecting biomolecular interactions. The use of labels is not required and the methods can be performed in a high-throughput manner. The invention also provides optical devices useful as narrow band filters.09-11-2008
20090148955Label-Free High-Throughput Optical Technique for Detecting Biomolecular Interactions - Methods and compositions are provided for detecting biomolecular interactions. The use of labels is not required and the methods can be performed in a high-throughput manner. The invention also provides optical devices useful as narrow band filters.06-11-2009
20090264314Optical Detection of Label-Free Biomolecular Interactions Using Microreplicated Plastic Sensor Elements - Methods and compositions are provided for detecting biomolecular interactions. The use of labels is not required and the methods can be performed in a high-throughput manner. The invention also provides optical devices useful as narrow band filters.10-22-2009
20100196925Methods for Screening Cells and Antibodies - The invention provides methods of detecting a change in cell growth patterns, methods of screening many different antibodies in one receptacle, and methods of detecting specific binding of an antibody to a protein or cell, wherein the antibody is in a mixture of many different antibodies.08-05-2010
20100231907Method and Apparatus for Biosensor Spectral Shift Detection - Performing high-resolution determination of the relative shift of the spectral properties of a biosensor. The shift in the resonance peak of the biosensor is indicative of the amount of material bound to the surface of the biosensor. A preferred biosensor is a Guided Mode Resonant Filter Biosensor (GMRFB). In one aspect of the invention, curve fitting is used to determine the relative location of the spectrum of the unexposed biosensor with respect to those spectra that are altered (e.g., shifted) by the presence of materials bound to the surface of the biosensor. In an alternative embodiment, the cross correlation function is used to detect spectral peak offsets between a reference spectrum and a spectrum measured from an exposed biosensor. In yet another alternative, maximal likelihood estimation techniques are used to determine the spectral shift or offs.09-16-2010

Patent applications by Peter Li, Andover, MA US

Xiang-Yi Li, Andover, MA US

Patent application numberDescriptionPublished
20090082313Multikinase Inhibitors for Use in the Treatment of Cancer - The present invention provides compounds, pharmaceutical compositions and methods for the treatment of specific cancers. Such compositions may generally comprise a compound of formula (I):03-26-2009
20090197867ENANTIOMERICALLY ENRICHED IMIDAZOAZEPINONE COMPOUNDS - The present invention provides an enantiomerically pure compound of Formula I:08-06-2009
20090291998EPONEMYCIN AND EPOXOMICIN ANALOGS AND USES THEREOF - The present invention provides compounds having formula (1): wherein R11-26-2009
20100093842Laulimalide Analogs and Uses Thereof - The present invention provides compounds having formula I:04-15-2010
20110105427DEAZAPURINES AND USES THEREOF - The present invention provides compounds having formula (I):05-05-2011
20110144101MACROCYCLIC COMPOUNDS USEFUL AS PHARMACEUTICALS - The present invention provides methods for the use of compounds having formula (I) in the treatment of various disorders including inflammatory or autoimmune disorders, and disorders involving malignancy or increased angiogenesis, wherein R06-16-2011

Patent applications by Xiang-Yi Li, Andover, MA US

Yunchu Li, Andover, MA US

Patent application numberDescriptionPublished
20080224908Mixer/DAC Chip and Method - An electronic chip has a data input for receiving an input digital data signal with a data frequency, a plurality of switches, and a logic circuit operatively coupled with both the plurality of switches and the data input. The logic circuit controls the switches to be in one of a DAC mode or a mixer mode. The DAC mode causes the switches to convert the input digital data signal into a DAC analog signal having about the data frequency. The mixer mode, however, causes the switches to convert the input digital data signal into a mixed analog signal having a mixer frequency that is higher than the data frequency.09-18-2008
20100301913CMOS Clock Receiver with Feedback Loop Error Corrections - A system for correcting duty cycle errors in a clock receiver that includes a differential amplifier having inputs for a pair of differential clock signals. A duty cycle error detector has inputs for a pair of amplified clock signals and an output for a duty cycle error correction signal. A signal conditioner is also provided with the differential amplifier having an input for the duty cycle error correction signal. Furthermore, the signal conditioner adjusts the differential clock signals in response to the duty cycle error correction signal. Also, a system for correcting cross point errors in a clock receiver that includes a differential amplifier having inputs for a pair of differential clock signal. A cross point error detector has inputs for a pair of amplified clock signals and an output for a cross point error correction signal. A signal conditioner is also provided with the differential amplifier having an input for the cross point error correction signal. Furthermore, the signal conditioner adjusts the differential clock signals in response to the cross point error correction signal.12-02-2010

Patent applications by Yunchu Li, Andover, MA US