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Ley, US
Andre Ley, Ferndale, MI US
| Patent application number | Description | Published |
|---|---|---|
| 20110246105 | METHOD AND APPARATUS FOR TESTING AT LEAST ONE TEMPERATURE SENSOR IN A VEHICLE - An apparatus and method for testing a temperature sensor in a vehicle is provided. The apparatus includes a power device. The power device is configured to receive a power signal and to filter the power signal to generate a filtered power signal. The power device is further configured to compare the filtered power signal to a first threshold and to test the temperature sensor based on the comparison of the filtered power signal to the first threshold. | 10-06-2011 |
Arthur C. Ley, Newtown, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20080274969 | Albumin-Fused Kunitz Domain Peptides - The invention relates to proteins comprising serine protease inhibiting peptides, such as Kunitz domain peptides (including, but not limited to, fragments and variants thereof) fused to albumin, or fragments or variants thereof. These fusion proteins are herein collectively referred to as “albumin fusion proteins of the invention.” These fusion proteins exhibit extended shelf-life and/or extended or therapeutic activity in solution. The invention encompasses therapeutic albumin fusion proteins, compositions, pharmaceutical compositions, formulations and kits. The invention also encompasses nucleic acid molecules and vectors encoding the albumin fusion proteins of the invention, host cells transformed with these nucleic acids and vectors, and methods of making the albumin fusion proteins of the invention using these nucleic acids, vectors, and/or host cells. The invention also relates to compositions and methods for inhibiting neutrophil elastase, kallikrein, and plasmin. The invention further relates to compositions and methods for treating cystic fibrosis and cancer. | 11-06-2008 |
| 20110092413 | Albumin-Fused Kunitz Domain Peptides - The invention relates to proteins comprising serine protease inhibiting peptides, such as Kunitz domain peptides (including, but not limited to, fragments and variants thereof) fused to albumin, or fragments or variants thereof. These fusion proteins are herein collectively referred to as “albumin fusion proteins of the invention.” These fusion proteins exhibit extended shelf-life and/or extended or therapeutic activity in solution. The invention encompasses therapeutic albumin fusion proteins, compositions, pharmaceutical compositions, formulations and kits. The invention also encompasses nucleic acid molecules and vectors encoding the albumin fusion proteins of the invention, host cells transformed with these nucleic acids and vectors, and methods of making the albumin fusion proteins of the invention using these nucleic acids, vectors, and/or host cells. The invention also relates to compositions and methods for inhibiting neutrophil elastase, kallikrein, and plasmin. The invention further relates to compositions and methods for treating cystic fibrosis and cancer. | 04-21-2011 |
Arthur Charles Ley, Newton, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20090234101 | DIRECTED EVOLUTION OF NOVEL BINDING PROTEINS - In order to obtain a novel binding protein against a chosen target, DNA molecules, each encoding a protein comprising one of a family of similar potential binding domains and a structural signal calling for the display of the protein on the outer surface of a chosen bacterial cell, bacterial spore or phage (genetic package) are introduced into a genetic package. The protein is expressed and the potential binding domain is displayed on the outer surface of the package. The cells or viruses bearing the binding domains which recognize the target molecule are isolated and amplified. The successful binding domains are then characterized. One or more of these successful binding domains is used as a model for the design of a new family of potential binding domains, and the process is repeated until a novel binding domain having a desired affinity for the target molecule is obtained. In one embodiment, the first family of potential binding domains is related to bovine pancreatic trypsin inhibitor, the genetic package is M13 phage, and the protein includes the outer surface transport signal of the M13 gene III protein. | 09-17-2009 |
Brian Robert Ley, Washington, MO US
| Patent application number | Description | Published |
|---|---|---|
| 20110031088 | Clutch Brake - A clutch brake for use in association with a braking mechanism for braking rotation of a shaft connecting an engine to a transmission. The clutch brake includes first and second clutch brake sections having first and second lock plates. The first and second clutch brake sections are selectively configurable in a disconnected configuration and a connected configuration. The clutch brake further comprises a fastening mechanism on the first and second lock plates for fastening the first and second clutch brake sections in the connected configuration. The fastening mechanism includes a first fastening component on the first lock plate and a second fastening component on the second lock plate. The first fastening component further includes a fastener body movably mounted in an opening in the first lock plate, and a fastening arm extending from the fastener body. The fastener body is movable from a fastening position, to a release position. | 02-10-2011 |
| 20110226579 | CENTRIFUGALLY ASSISTED CLUTCH - A friction clutch assembly connects driving and driven shafts and has a pressure plate axially moveable between an engaged position transmitting torque from the driving shaft to the driven shaft and a disengaged position. The assembly includes levers and a plurality of centrifugal-assist weights on the levers adjacent outer ends of the levers. The centrifugal-assist weights are arranged to apply an increased force urging the pressure plate to its engaged position upon rotation of the cover and the levers. The centrifugal-assist weights are suitably configured to provided the desired amount of increased force. | 09-22-2011 |
Bruce Calvin Ley, Ossian, IN US
| Patent application number | Description | Published |
|---|---|---|
| 20080295543 | WASHING MACHINE APPARATUS AND METHOD - A washing machine is provided that includes an induction motor and a motor control circuit with a feedback loop. The feedback loop provides rotor speed to a microprocessor of the motor control circuit. The motor control circuit and feedback loop control the motor such that the motor operates in a reverse frequency mode which provides braking to the washing machine. | 12-04-2008 |
| 20080297011 | INTEGRATED CONTROLLER/MOTOR WITH THERMAL OVERLOAD SENSOR - An integrated controller/motor energized by a power supply includes a controller that has controller circuits and a pair of controller lead lines connectable in circuit between the power supply and the controller circuits. The integrated controller/motor also includes a motor that has a first motor winding and a second motor winding each in circuit with the controller circuits and a thermal overload sensor located in direct proximity to the first motor winding and the second motor winding. The thermal overload sensor may be connected in series with at least one of the controller lead lines. A method of protecting an integrated controller/motor from thermal overload is also presented. | 12-04-2008 |
| 20080297098 | WASHING MACHINE APPARATUS AND METHOD - A washing machine is provided that includes an induction motor and a motor control circuit with a feedback loop. The feedback loop provides rotor speed to a microprocessor of the motor control circuit. The motor control circuit and feedback loop control the motor such that the motor operates in a negative slip mode which provides braking to the washing machine. | 12-04-2008 |
| 20080297275 | DUAL CONFIGURATION FILTER CIRCUIT - A low current leakage circuit for power source lines that include a first power line at one potential and a second power line at another potential with respect to the first power line and that carry energy to power a device is provided. The low leakage circuit may include a filter circuit connected in parallel with the device and between the first power line and the second power line. The filter circuit may have a junction in circuit with a local ground and a switch may be connected in series between the junction and the local ground. A method of reducing current leakage in a filter circuit for power source lines carrying energy for powering a device is also provided. | 12-04-2008 |
| 20090160276 | MOTOR ASSEMBLY - A motor includes a rotor core and a stator core disposed about the rotor core. The stator core includes three support portions and at least one end bracket supporting the stator core solely by three mounting portions that are interconnected with a respective support portion. A method of mounting an end shield to a laminated motor stator core is also presented. | 06-25-2009 |
| 20100107498 | GARAGE DOOR OPENER - This invention relates generally to a garage door opener. The garage door opener has a user interface and a motor operatively connected to the garage door, at least one sensor, and an integrated motor control circuit. The integrated motor control circuit has a motor control microprocessor and a memory. The memory contains previous operation data. The motor control microprocessor receives data from the user interface, the memory and the sensors to control the motor. | 05-06-2010 |
Geoffrey Thomas Ley, Dallas, TX US
| Patent application number | Description | Published |
|---|---|---|
| 20110052777 | Method for Making a Rolled Snack Food Product Having a Light Crispy Texture - A method for making a cooked rolled snack food from a starch based dough. The starch based dough is admixed with a small average particle size monoglyceride. The dough is then rolled and cooked in hot oil. The fatty acid chain is disposed within the helical amylose molecules in the starch-based dough and provides structural support within the helix. This support helps control inward expansion of the rolled dough snack during frying. | 03-03-2011 |
Gregory R. Ley, New Brighton, MN US
| Patent application number | Description | Published |
|---|---|---|
| 20080262587 | EXTENDABLE AND RETRACTABLE LEAD HAVING A SNAP-FIT TERMINAL CONNECTOR - A lead having an extendable and retractable fixation mechanism has a rotating terminal pin at the terminal end which rotates the fixation mechanism at the distal end. As the terminal pin is rotated, the fixation mechanism is extended or retracted from the distal end of the lead. A threaded collar allows for the fixation mechanism to smoothly extend and retract from the lead, and allows for a 1:1 turn ratio between the terminal pin and the fixation mechanism. A fluoroscopic ring disposed at the distal end of the lead provides information during the implantation process. | 10-23-2008 |
Herbert F. Ley, Wellsboro, PA US
| Patent application number | Description | Published |
|---|---|---|
| 20110249335 | LENS COVERING AND CLEANING APPARATUS - An apparatus including a cap adapted for covering, protecting and cleaning a lens of a device such as a scope of a firearm. The cap may be manipulated to clean the lens, such that when the cap is opened, the lens is clean, with the scope ready for use. | 10-13-2011 |
Joseph W. Ley, Tucson, AZ US
| Patent application number | Description | Published |
|---|---|---|
| 20110287541 | ACCORDION BIOREACTOR - Disclosed herein are bioreactors including a first sheet and a second sheet (one or both of which is substantially transparent to light), wherein the second sheet is disposed adjacent to the first sheet, and the first and second sheets are sealed along a first longitudinal edge, a second longitudinal edge, a first horizontal edge, a second horizontal edge, and at least one intermediate horizontal seal between the first horizontal edge and the second horizontal edge, thereby forming at least two chambers for holding fluid in series along a vertical axis, wherein each of the two or more chambers is oriented at an angle relative to the vertical axis, wherein the angle is about 0° to about 90° and at least one of the chambers is oriented at an angle greater than 0°, and wherein there is at least one opening in each of the first horizontal edge, the second horizontal edge, and intermediate horizontal seal(s); a support structure comprising at least one horizontal support, wherein the horizontal support is located at or near the position of the intermediate horizontal seal; a reservoir below the second horizontal edge of the first and second sheets; and a means for pumping fluid from the reservoir to the first horizontal edge of the first and second sheets. Also disclosed are methods of culturing cells including circulating a suspension of cells in a disclosed bioreactor. In some examples, the cells include microalgae, macroalgae, bacteria, fungi, insect cells, plant cells, animal cells (such as mammalian cells), or plant or animals tissue or organs. In particular examples, the method includes exposing the culture in the bioreactor to a light source (such as sunlight or an artificial light source). | 11-24-2011 |
Josh Ley, Erie, CO US
| Patent application number | Description | Published |
|---|---|---|
| 20080278020 | STATOR FOR PERMANENT MAGNET ELECTRIC MOTOR USING SOFT MAGNETIC COMPOSITES - A stator of an electrical machine operable as a motor or a generator, applicable to a radial-axial type machine. The stator includes a plurality of stator segments disposed circumferentially about an axis. Each segment has a generally wedge shaped core and a winding wound around the core. The winding is bent to have portions that are disposed on multiple planes. The core includes an elongated wedge tip portions aligned parallel to the axis and an outer radial face opposite to the tip portion. The multiple planes include at least one plane substantially normal to the axis and at least one plane tangential to the radial face. | 11-13-2008 |
| 20080278021 | Stress Distributing Permanent Magnet Rotor Geometry For Electric Machines - A rotor includes a cylindrical rotor core having an outer circumferential surface and a plurality of magnet insertion holes formed in the rotor core and arranged circumferentially at a preset angular interval about the rotational axis of the rotor core. Each hole extends in a direction parallel to the rotational axis and has a cross section of a generally elongated slit. The elongated slit is curved concave relative to the circumferential surface and has a radially inward side, a radially outward side, and two ends that are respectively spaced apart from the circumferential surface by two bridges, wherein each bridge has thinner and thicker portions that are respectively positioned near the radially inward and outward sides. One or more permanent magnets are inserted in each hole and arranged to transfer centrifugal forces acting on the magnets during operation to portions of the bridges. | 11-13-2008 |
| 20110121677 | ROTOR FOR A PERMANENT MAGNET ELECTRIC MACHINE - A rotor for a permanent magnet electric motor includes a rotor core having a generally cylindrical shape with an outer circumferential surface and a rotational axis and a plurality of magnet insertion hole arrangements formed in the rotor core and arranged circumferentially at a preset angular interval about the rotational axis. Each hole arrangement has a radially inward side, a radially outward side, and two ends that are respectively spaced apart from the circumferential surface by respective bridge regions formed by the rotor core. The material of the bridge regions is metallurgically transformed by having its grain structure changed, e.g., by heating the material to at least its Curie temperature, whereby the material possesses greater magnetic reluctance than the material of adjacent portions of the rotor core. | 05-26-2011 |
Kevin Ley, Santa Fe, NM US
| Patent application number | Description | Published |
|---|---|---|
| 20080213747 | FLUORESCENT POLYMER SUPERQUENCHING-BASED BIOASSAYS - A chemical composition including a fluorescent polymer and a receptor that is specific for both a target biological agent and a chemical moiety including (a) a recognition element, (b) a tethering element, and (c) a property-altering element is disclosed. Both the fluorescent polymer and the receptor are co-located on a support. When the chemical moiety is bound to the receptor, the property-altering element is sufficiently close to the fluorescent polymer to alter the fluorescence emitted by the polymer. When an analyte sample is introduced, the target biological agent, if present, binds to the receptor, thereby displacing the chemical moiety from the receptor, resulting in an increase of detected fluorescence. Assays for detecting the presence of a target biological agent are also disclosed. | 09-04-2008 |
Kevin R. Ley, Elk River, MN US
| Patent application number | Description | Published |
|---|---|---|
| 20080234744 | SPINAL STABILIZATION SYSTEM WITH RIGID AND FLEXIBLE ELEMENTS - A spinal stabilization system generally comprises first and second anchor members configured to be secured to first and second vertebrae within a patient's body, a flexible element secured to the first anchor member, and a rigid element secured to the second anchor member. An end portion of the rigid element is coupled to an end portion of the flexible so that the system is able to provide both rigid and dynamic stabilization. The coupling is maintained even if the flexible element relaxes after a period of time within the patient's body. | 09-25-2008 |
| 20120016421 | SPINAL STABILIZATION SYSTEM WITH RIGID AND FLEXIBLE ELEMENTS - A spinal stabilization system generally comprises first and second anchor members configured to be secured to first and second vertebrae within a patient's body, a flexible element secured to the first anchor member, and a rigid element secured to the second anchor member. An end portion of the rigid element is coupled to an end portion of the flexible so that the system is able to provide both rigid and dynamic stabilization. The coupling is maintained even if the flexible element relaxes after a period of time within the patient's body. | 01-19-2012 |
Klaus Ley, La Jolla, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20120121590 | METHODS OF INHIBITING ADVERSE CARDIAC EVENTS AND TREATING ATHEROSCLEROSIS AND CORONARY ARTERY DISEASE USING GALECTIN-3 BINDING PROTEIN (GAL-3BP, BTBD17B, MAC-2 BINDING PROTEIN) - The invention provides Galectin-3 binding protein (Gal-3BP, BTBD17B) polypeptide sequences and compositions that include Gal-3BP polypeptide sequences, and methods of using Gal-3BP polypeptide sequences, including modified forms and wild type (native) forms of Gal-3BP polypeptide, such as in treatment, diagnostic, detection and prognostic methods. | 05-17-2012 |
Klaus F. Ley, La Jolla, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20090022712 | Compositions and Methods for Inhibiting Leukocyte Function - The present invention provides compositions and methods for regulating leukocyte migration and function. The present invention also provides compositions and methods for preventing and inhibiting lung injury and damage associated with neutrophil infiltration of the lung. | 01-22-2009 |
| 20090093005 | PROTEIN-BASED BIOMARKERS FOR ABDOMINAL AORTIC ANEURYSM - The present invention encompasses compositions and methods useful for diagnosing subjects with abdominal aortic aneurysms. The invention relates to the use of protein biomarkers whose levels are different in subjects with abdominal aortic aneurysms relative to normal subjects. | 04-09-2009 |
| 20100055723 | Galectin-3-Binding Protein as a Biomarker of Cardiovascular Disease - The present invention provides compositions and methods for using biomarkers to diagnose and monitor cardiovascular associated diseases and disorders. More specifically, the present invention provides Galectin-3-binding protein as a biomarker for disease. | 03-04-2010 |
Michael Scott Ley, Moon Township, PA US
| Patent application number | Description | Published |
|---|---|---|
| 20090204538 | USER INTERFACE AND SYSTEM INCLUDING SAME - A graphical user interface including a controller for redistributing funds between a first account and a second account. The controller includes a slidable element positionable over a fixed background element to define a first segment and a second segment of the background element. A length of the first segment is representative of a balance of the first account, and a length of the second segment is representative of a balance of the second account. | 08-13-2009 |
M. Tyler Ley, Stillwater, OK US
| Patent application number | Description | Published |
|---|---|---|
| 20120007579 | EMBEDDED WIRELESS CORROSION SENSOR - A corrosion sensor is disclosed. The corrosion sensor has a retainer and a microcontroller retained by the retainer. A length of antenna wire arranged in a wound configuration is retained by the retainer and connected to the microcontroller. A corrosion sensitive element is conductively connected to the microcontroller. The microcontroller is programmed to receive a power signal from the antenna wire and test for corrosion of the corrosion sensitive element. The he microcontroller is also programmed to transmit a signal indicative of the test results via the antenna. | 01-12-2012 |
Ruth E. Ley, St. Louis, MO US
| Patent application number | Description | Published |
|---|---|---|
| 20100172874 | GUT MICROBIOME AS A BIOMARKER AND THERAPEUTIC TARGET FOR TREATING OBESITY OR AN OBESITY RELATED DISORDER - The present invention relates to the gut microbiome as a biomarker and therapeutic target for energy harvesting, weight loss or gain, and/or obesity in a subject. In particular, the invention provides methods of altering and monitoring the relative abundance of | 07-08-2010 |
Thomas A. Ley, La Crosse, WI US
| Patent application number | Description | Published |
|---|---|---|
| 20110064571 | Secondary Inlet Cone for a Plenum Fan - A plenum fan comprising a fan wheel disposed within a box-like enclosure includes a secondary inlet cone, a primary inlet cone, and a flexible duct. The two inlet cones convey air to the mouth of the fan wheel. A frame supports the fan wheel and the primary inlet cone such that the frame, the fan wheel and the primary inlet cone comprise a fan assembly. If the fan assembly shifts due to fan thrust or vibration, the fan assembly moves as a unit. The flexible duct connects the primary inlet cone to an inlet of the enclosure while isolating the fan assembly's vibration from the enclosure. The secondary inlet cone extends from the inlet of the enclosure, protrudes into or toward the primary inlet cone and provides a smooth airflow path over the abrupt shape of the flexible duct. | 03-17-2011 |
Timothy J. Ley, Shoreview, MN US
| Patent application number | Description | Published |
|---|---|---|
| 20080319531 | FLEXIBLE AND EXPANDABLE STENT - In one embodiment of the invention, a stent may be provided comprising a first undulating band having alternating peaks and troughs, a second undulating band having alternating peaks and troughs, a first substantially longitudinal connector extending between the first and second undulating bands and a second very short connector extending between the first and second undulating bands, the first connector substantially longer than the second very short connector. | 12-25-2008 |
| 20100131047 | Stent Cell Configurations - A generally cylindrical, radially expandable stent may be composed of a plurality of interconnected multibonate cell structures. The cells have three or more enlarged end portions radiating from a common center within the cell. The cells may be of tribonate or higher order multibonate configuration. Stents composed up of a series of generally multibonate cell elements are also disclosed. | 05-27-2010 |
| 20100132718 | Occlusion Stent - A device for occluding a target body lumen, comprises a wire structure defining a wire structure lumen extending therethrough and movable between a reduced diameter insertion configuration and an expanded diameter deployed configuration and a basket structure extending across the wire structure lumen and including therein a cell growth promoting agent to promote cell growth across the wire structure lumen to occlude the target body lumen. | 06-03-2010 |
| 20110282435 | Longitudinally Flexible Expandable Stent - Segmented articulatable stent of open structure comprised of end-connected struts of first and second lengths making up first and second segments with angular interconnects between adjacent first and second segments. | 11-17-2011 |
Tom Ley, Cupertino, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20080284047 | Chip Package with Stiffener Ring - Various semiconductor chip packages and methods of making the same are provided. In one aspect, a method of manufacturing is provided that includes providing a substrate that has a first side and a first plurality of passive devices in the first side. A polymeric stiffener ring is formed on the first side. The stiffener ring embeds the first plurality of passive devices without covering a central portion of the first surface of the substrate. A semiconductor chip is mounted on the central portion of the first surface of the substrate. | 11-20-2008 |
| 20090200659 | Chip Package with Channel Stiffener Frame - Various semiconductor chip packages and methods of making the same are provided. In one aspect, a method of manufacturing is provided that includes providing a substrate that has a first side and a first plurality of passive devices on the first side. A stiffener frame is coupled on the first side. The stiffener frame has first and second spaced apart opposing walls that define a channel in which the first plurality of passive devices is positioned, and a central opening that does not cover a central portion of the first side of the substrate. | 08-13-2009 |
| 20110241161 | CHIP PACKAGE WITH CHANNEL STIFFENER FRAME - Various semiconductor chip packages and methods of making the same are provided. In one aspect, a method of manufacturing is provided that includes providing a substrate that has a first side and a first plurality of passive devices on the first side. A stiffener frame is coupled on the first side. The stiffener frame has first and second spaced apart opposing walls that define a channel in which the first plurality of passive devices is positioned, and a central opening that does not cover a central portion of the first side of the substrate. | 10-06-2011 |
Vance Ley, Albuquerque, NM US
| Patent application number | Description | Published |
|---|---|---|
| 20090155951 | Exponentially Doped Layers In Inverted Metamorphic Multijunction Solar Cells - A method of forming a multijunction solar cell including an upper subcell, a middle subcell, and a lower subcell, including providing first substrate for the epitaxial growth of semiconductor material; forming a first solar subcell on the substrate having a first band gap; forming a second solar subcell over the first solar subcell having a second band gap smaller than the first band gap; forming a grading interlayer over the second subcell, the grading interlayer having a third band gap greater than the second band gap; and forming a third solar subcell over the grading interlayer having a fourth band gap smaller than the second band gap such that the third subcell is lattice mis-matched with respect to the second subcell, wherein at least one of the bases of a solar subcell has an exponentially doped profile. | 06-18-2009 |
| 20090155952 | Exponentially Doped Layers In Inverted Metamorphic Multijunction Solar Cells - A method of forming a multifunction solar cell including an upper subcell, a middle subcell, and a lower subcell, including providing first substrate for the epitaxial growth of semiconductor material; forming a first solar subcell on the substrate having a first band gap; forming a second solar subcell over the first solar subcell having a second band gap smaller than the first band gap; forming a grading interlayer over the second subcell, the grading interlayer having a third band gap greater than the second band gap; and forming a third solar subcell over the grading interlayer having a fourth band gap smaller than the second band gap such that the third subcell is lattice mismatched with respect to the second subcell, wherein at least one of the bases of a solar subcell has an exponentially doped profile. | 06-18-2009 |