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Lesho, US
Jeffery C. Lesho, Brookeville, MD US
| Patent application number | Description | Published |
|---|---|---|
| 20090146078 | SYSTEMS AND METHODS FOR EXTENDING THE USEFUL LIFE OF OPTICAL SENSORS - The present invention provides a method for increasing the lifetime of an optical sensor. In one aspect, the method includes the step of configuring the optical sensor so that the duty cycle of sensor's radiant source is less than 100% over a continuous period amount of time when the sensor is periodically obtaining data regarding an analyte. By operating the sensor according to the above inventive method, the indicator molecules of the optical sensor are not excited during the entire continuous period of time during which the sensor is needed to provide data regarding the presence or concentration of a substance. Thus, the method increases the life of the indicator molecules. | 06-11-2009 |
| 20090264718 | IMPLANTED SENSOR PROCESSING SYSTEM AND METHOD FOR PROCESSING IMPLANTED SENSOR OUTPUT - A quantitative measurement system includes an external unit and an internal unit are provided for obtaining quantitative analyte measurements, such as within the body. In one example of an application of the system, the internal unit would be implanted either subcutaneously or otherwise within the body of a subject. The internal unit contains optoelectronics circuitry, a component of which may be comprised of a fluorescence sensing device. The optoelectronics circuitry obtains quantitative measurement information and modifies a load as a function of the obtained information. The load in turn varies the amount of current through coil, which is coupled to a coil of the external unit. A demodulator detects the current variations induced in the external coil by the internal coil coupled thereto, and applies the detected signal to processing circuitry, such as a pulse counter and computer interface, for processing the signal into computer-readable format for inputting to a computer. | 10-22-2009 |
Jeffrey C. Lesho, Brookville, MD US
| Patent application number | Description | Published |
|---|---|---|
| 20090039286 | SYSTEM AND METHOD FOR ATTENUATING THE EFFECT OF AMBIENT LIGHT ON AN OPTICAL SENSOR - The present invention provides systems and methods for attenuating the effect of ambient light on optical sensors and for measuring and compensating quantitatively for the ambient light. | 02-12-2009 |
Mathew J. Lesho, San Mateo, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20090076731 | METHOD AND DEVICE AND PREDICTING PHYSIOLOGICAL VALUES - The invention relates generally to methods, systems, and devices for measuring the concentration of target analytes present in a biological system using a series of measurements obtained from a monitoring system and a Mixtures of Experts (MOE) algorithm. In one embodiment, the present invention describes a method for measuring blood glucose in a subject. | 03-19-2009 |
Matthew J. Lesho, Ellicott City, MD US
| Patent application number | Description | Published |
|---|---|---|
| 20100075863 | ROTARY ARRAY MODULE FOR MULTIPLEXING SPOT-BASED OPTICAL READOUTS - An apparatus for multiplexing detection of one or more of a plurality of target molecules in a liquid sample includes a sample chamber adapted to receive a liquid sample containing one or more target molecules and a rotary array disposed in the sample chamber. The rotary array includes a plurality of spots, with each spot including at least one probe molecule selected to bind to a particular region of a target molecule. The apparatus also includes an optical detector capable of determining if a target molecule has bound to one of the probe molecules as the array rotates within the sample chamber. | 03-25-2010 |
Matthew J. Lesho, San Mateo, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20080262334 | METHOD AND DEVICE FOR PREDICTING PHYSIOLOGICAL VALUES - The invention relates generally to methods, systems, and devices for measuring the concentration of target analytes present in a biological system using a series of measurements obtained from a monitoring system and a Mixtures of Experts (MOE) algorithm. In one embodiment, the present invention describes a method for measuring blood glucose in a subject. | 10-23-2008 |
| 20080262746 | METHOD AND DEVICE FOR PREDICTING PHYSIOLOGICAL VALUES - The invention relates generally to methods, systems, and devices for measuring the concentration of target analytes present in a biological system using a series of measurements obtained from a monitoring system and a Mixtures of Experts (MOE) algorithm. In one embodiment, the present invention describes a method for measuring blood glucose in a subject. | 10-23-2008 |
| 20080270039 | METHOD AND DEVICE FOR PREDICTING PHYSIOLOGICAL VALUES - The invention relates generally to methods, systems, and devices for measuring the concentration of target analytes present in a biological system using a series of measurements obtained from a monitoring system and a Mixtures of Experts (MOE) algorithm. In one embodiment, the present invention describes a method for measuring blood glucose in a subject. | 10-30-2008 |
