Patent application number | Description | Published |
20100198523 | DETERMINING PARTICLE PROPERTIES BY MEANS OF SUPERIMPOSED FIELDS - The aim of the invention is to model the gravitational field-induced or centrifugal field-induced separation of particles of a dispersion by means of one or more additional force fields that also influence the migration of the particles. Said aim is achieved by detecting and measuring the modified separation behavior with the help of concentration-measuring sensors. The force acting upon the particles can be calculated from the change in velocity of the particles, and the corresponding particle properties can be calculated if the respective field intensities are known. | 08-05-2010 |
20110098462 | METHOD AND KIT FOR THE SAMPLE PRESERVATION AND CELL DISRUPTION BEFORE THE EXTRACTION OF NUCLEIC ACIDS - The invention relates to a method for preserving samples and disrupting cells which can be employed for the preparation of the extraction of nucleic acids from live cells, cell aggregates and tissue samples, and to a kit for carrying out the method. The method includes the introduction of live cells, cell aggregates or tissue samples whose nucleic acids are to be extracted into an excess of water-miscible and volatile organic liquid. The saturation of the sample with the organic liquid has an advantageous effect on the extraction of the nucleic acids, which is subsequently carried out in an aqueous medium. The mechanical cell disruption is facilitated by the virtually complete removal of the water from the cells. The biomembranes are dissolved in the organic liquid. tRNA and other RNA fractions with a low degree of polymerization, which are capable of permeating across the cell wall, can be extracted selectively without mechanical disruption. Before high-molecular-weight nucleic acids are extracted, the cells, cell aggregates or tissue samples are disrupted in the organic liquid with the aid of mechanical pulses. Since the nucleases are inactive in the dehydrated organic liquid, the biological samples or the homogenates prepared therefrom can be stored at room temperature in the organic liquid as long as desired. After incubation in the largely anhydrous organic liquid, the sample's nucleases are largely denatured. An advantageous kit according to the invention contains a mixed organic/aqueous phase with denaturing properties and, for each sample, a shaped body for dehydration which is adapted to suit the size of the preservation container, and a mixture, adapted to suit the size of the preservation container, of a few large and many small disruption bodies for the disruption in the nonaqueous medium. A considerable advantage of the invention is the fact that cooling and powerful mechanical pulses when disrupting the cells and during the extraction may be dispensed with, and that DNA extraction and cell disruption can be carried out at different times. | 04-28-2011 |
20110207163 | METHOD FOR AND MATERIAL OF A SHAPE STANDARD - A method is disclosed for the preparation of isomorphic and nonspherical shape standards as isometric as possible and their mixtures for validation of the measurement methods and analyzers for quantification of particle shapes and their characteristics especially in the microscale and nanoscale size range. Furthermore the shape standards also provide quality control and performance qualification can be used at the operator of the corresponding shape measurement devices. | 08-25-2011 |
20110282590 | DETERMINING PARTICLE PROPERTIES BY MEANS OF SUPERIMPOSED FIELDS - The aim of the invention is to model the gravitational field-induced or centrifugal field-induced separation of particles of a dispersion by means of one or more additional force fields that also influence the migration of the particles. Said aim is achieved by detecting and measuring the modified separation behavior with the help of concentration-measuring sensors. The force acting upon the particles can be calculated from the change in velocity of the particles, and the corresponding particle properties can be calculated if the respective field intensities are known. | 11-17-2011 |
20120293799 | Method and Device for the Characterization of Multiple Samples of One or Various Dispersions - A method and a device for the automatic determination of selected physical and colloidal chemistry parameters by determining the attenuation of radiated waves through monodisperse or polydisperse dispersion samples subjected to gravitation or centrifugation, wherein during the segregation by means of centrifugation or gravitation, the instantaneous transmission I | 11-22-2012 |
20140371047 | CENTRIFUGE ROTOR - A centrifuge rotor for measuring a characteristic of a sample subjected to centrifugation, the centrifuge rotor including: a rotor body; at least one sample holder for holding a sample; at least one on-board measurement device for measuring a characteristic of the sample held in the at least one sample holder during rotation of the rotor. | 12-18-2014 |
Patent application number | Description | Published |
20100233096 | METHOD TO PRODUCE HYPERPOLARISED CARBOXYLATES AND SULPHONATES - The invention relates to a dynamic nuclear polarisation method for producing hyperpolarised carboxylates or sulphonates or mixtures thereof wherein the carboxylate or sulphonate used in the method of the invention comprises certain inorganic cations. The invention further relates to compositions for use in that method. | 09-16-2010 |
20130096420 | Process For Preparing Hyperpolarized Substrates And Method For MRI - The present invention generally relates to a process for the preparation of aqueous solutions of hyperpolarized molecules ready for use in in-vivo MR diagnostic imaging, the use thereof as MRI contrast agent in investigation methods for producing diagnostic MR images of a human or non-human animal body organ, region or tissue. | 04-18-2013 |
20140257085 | Process For The Preparation Of Hyperpolarized Derivatives For Use In MRI Analysis - The present invention relates to a process for the preparation of aqueous solutions of hyperpolarized carboxylic organic acids ready for use in in-vivo MR diagnostic imaging, and the use of the corresponding anhydrides or esters as glass-forming agents. | 09-11-2014 |
20140343402 | Composition Comprising Acetic Anhydride And A Gadolinium Complex, And Method For The Use In Hyperpolarisation In MRI Analysis - The present invention generally relates to a composition comprising acetic anhydride, a DNP agent and a gadolinium complex and its use for the preparation of hyperpolarised imaging agent for MR diagnostic analysis. | 11-20-2014 |
20150118159 | HYPERPOLARIZED AMINO ACIDS - Method for manufacturing a hyperpolarized amino acid, in particular glutamine, which substantially limits the formation of by-products, with respect to conventional aqueous preparations of sodium hydroxide with amino acids. The amino acid is in particular admixed with the hydroxide in the substantial absence of water and the dry mixture is dissolved in an anhydrous solvent in the presence of a polarizing agent. The obtained mixture is then subjected to a DNP process and can be used in metabolic MR imaging. | 04-30-2015 |
20150151009 | TRIARYLMETHYL RADICALS - New radical compounds, useful in the field of MRI imaging of formula (I). The radical compounds are in particular new triarylmethyl (“trityl”) radicals which can be used as polarizing agents for polarizing a molecule in the DNP process. | 06-04-2015 |
20150273086 | HYPERPOLARIZED 2-OXOGLUTARATE AS METABOLIC AGENT IN MR - Hyperpolarized 1- | 10-01-2015 |
Patent application number | Description | Published |
20090168606 | INTERACTIVE AND/OR SECURE ACIVATION OF A TOOL - A tool activation system and method includes receiving an authorization code of a user to verify access rights of a user to activate the tool. In one example, the authorization code is receive from a smart card. The environment around the tool, which can be in a wellbore, for example, is checked. In response to the authorization code and the checking of the environment, activation of the tool is enabled. | 07-02-2009 |
20100286800 | TRACTOR COMMUNICATION/CONTROL AND SELECT FIRE PERFORATING SWITCH SIMULATIONS - Apparatus and methods for controlling and communicating with one or more tools in a downhole tool string including a tractor, an auxiliary tractor tool, a logging tool, a safety sub, a release mechanism, a unit containing sensors for monitoring downhole conditions, a setting tool, and a perforating gun. Control and communication are accomplished by sending signals from the surface to control switches in the control units on the tool, with redundant switches for safety, to state machines in the respective control units, each state machine returning a signal verifying switch status to the surface. The state machine need not return a signal including a unique identifier. | 11-11-2010 |
20110066378 | Apparatus and Methods for Controlling and Communicating with Downhole Devices - Apparatus and methods for controlling and communicating with one or more tools in a downhole tool string including a tractor, an auxiliary tractor tool, a logging tool, a safety sub, a release mechanism, a unit containing sensors for monitoring downhole conditions, a setting tool, and a perforating gun. Also provided are apparatus and methods for controlling and communicating with one or more perforating guns, release devices, and explosive devices in a string to be lowered into a wellbore. Control and communication are accomplished by sending signals from the surface to control switches in the control units on the tool, with redundant switches for safety, to state machines in the respective control units, each state machine returning a signal verifying switch status to the surface. Control and power functions are accomplished with voltage of different polarities for safety. | 03-17-2011 |
20110090091 | Apparatus and methods for controlling and communicating with downwhole devices - Apparatus and methods for controlling and communicating with one or more tools in a downhole tool string including a tractor, an auxiliary tractor tool, a logging tool, a safety sub, a release mechanism, a unit containing sensors for monitoring downhole conditions, a setting tool, and a perforating gun. Also provided are apparatus and methods for controlling and communicating with one or more perforating guns, release devices, and explosive devices in a string to be lowered into a wellbore. Control and communication are accomplished by sending signals from the surface to control switches in the control units on the tool, with redundant switches for safety, to state machines in the respective control units, “each state machine returning a signal verifying switch status to the surface. Control and power functions are accomplished with voltage of different polarities for safety. | 04-21-2011 |
20120168226 | METHOD OF FABRICATION AND USE OF INTEGRATED DETONATORS - A detonator assembly is provided for use in oilfield operations to detonate an explosive downhole including a capacitor discharge unit and initiator electrically connected together to form a single unit. Further, provided is a method of fabricating an integrated detonator. Additionally, a method of use for an integrated detonating unit is provided. | 07-05-2012 |
20130042780 | High voltage explosive assembly for downhole detonations - A downhole explosive detonation comprises a high voltage electro-explosive initiator comprising an input high voltage power supply with a low impedance shunting fuse, a flexible electrical link and a capacitor discharge unit. Explosive is initiated in a direction approximately parallel, or in another version perpendicular to the capacitor discharge unit. A unique configuration and construction of the assembly allows installation through a small service port in the gun housing structure for more efficient gun arming. A real time downhole voltage monitoring is described that transmits voltage readings to the surface during a firing sequence. | 02-21-2013 |
20130220613 | Transient control of wellbore pressure - A method and apparatus is described for modifying downhole wellbore pressure at the instant that an explosive event occurs. By a significant temporary reduction in wellbore pressure, for example, an explosive cutter will be able to cut through thicker pipe in a deep well with high hydrostatic pressure. A favorable transient wellbore pressure is achieved by the selective timing of implosion and explosion devices, to improve the performance of certain explosive tools when subsequently initiated, such as shaped charge explosive cutters, severing tools, setting tools and perforating guns. As part of the system, each implosion or explosion device is initiated by a detonator having a preprogrammed control unit with a preselected timing delay to take advantage of the temporarily lowered wellbore pressure. | 08-29-2013 |
20130300569 | Apparatus and Methods for Controlling and Communicating with Downhole Devices - Apparatus and methods for controlling and communicating with one or more tools in a downhole tool string including a tractor, an auxiliary tractor tool, a logging tool, a safety sub, a release mechanism, a unit containing sensors for monitoring downhole conditions, a setting tool, and a perforating gun. Also provided are apparatus and methods for controlling and communicating with one or more perforating guns, release devices, and explosive devices in a string to be lowered into a wellbore. Control and communication are accomplished by sending signals from the surface to control switches in the control units on the tool, with redundant switches for safety, to state machines in the respective control units, “each state machine returning a signal verifying switch status to the surface. Control and power functions are accomplished with voltage of different polarities for safety. | 11-14-2013 |
20140151018 | Tractor Communication/Control and Select Fire Perforating Switch Simulations - Apparatus and methods for controlling and communicating with one or more tools in a downhole tool string including a tractor, an auxiliary tractor tool, a logging tool, a safety sub, a release mechanism, a unit containing sensors for monitoring downhole conditions, a setting tool, and a perforating gun. Control and communication are accomplished by sending signals from the surface to control switches in the control units on the tool, with redundant switches for safety, to state machines in the respective control units, each state machine returning a signal verifying switch status to the surface. The state machine need not return a signal including a unique identifier. | 06-05-2014 |
20150292849 | High Voltage Explosive assembly for downhole detonations - A downhole explosive detonation comprises a high voltage electro-explosive initiator comprising an input high voltage power supply with a low impedance shunting fuse, a flexible electrical link and a capacitor discharge unit. Explosive is initiated in a direction approximately parallel, or in another version perpendicular to the capacitor discharge unit. A unique configuration and construction of the assembly allows installation through a small service port in the gun housing structure for more efficient gun arming. A real time downhole voltage monitoring is described that transmits voltage readings to the surface during a firing sequence. | 10-15-2015 |