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Leonore A. Herzenberg, Stanford US

Leonore A. Herzenberg, Stanford, CA US

Patent application numberDescriptionPublished
20090074813Compositions And Methods Using Variant Tat Proteins - The present invention relates to methods to activate peripheral blood mononuclear cells. The present invention further provides methods for the identification of blocking agents of Tat protein activation of PBMCs and for identifying an active portion of a Tat polypeptide for incorporation as an immunogen in a vaccine. The present invention also provides an immunogen comprising an isolated variant of wild-type HIV Tat protein that exhibits reduced HIV priming of competent cells in comparison to the wild-type HIV Tat protein. The present invention further provides a diagnostic kit for identifying blocking agents for HIV Tat protein.03-19-2009
20090192227N-Acetylcysteine Compositions and Methods for Treating Acute Exacerbations of Inflammatory Lung Disease - The present invention relates to N-acetylcysteine compositions and methods for treating inflammation and redox imbalance in acute exacerbations of inflammatory lung disease.07-30-2009
20090258792Prostate Cancer Glycan Markers and Autoantibody Signatures - Disclosed are methods for probing the immunogenic sugar moieties of prostate cancer cells. The methods detect a number of glyco-epitopes that are highly and differentially expressed among prostate cancers of various Gleason grades. The glyco-epitopes exist on the surfaces of prostate cells. The methods also comprise the detection of autoantibodies in prostate cancer subjects. The antibodies bound to a glyco-motif of N-glycans that is normally “cryptic.” This target is highly expressed in prostate cancers. Lectins and antibodies that detect these glyco-epitopes that expressed in prostate cancer tissues include 10-15-2009
20100112628METHODS AND ASSAYS FOR DETECTING AND QUANTIFYING PURE SUBPOPULATIONS OF WHITE BLOOD CELLS IN IMMUNE SYSTEM DISORDERS - Methods for detecting nonactivated basophils in a whole blood sample obtained from a normal healthy subject, methods for determining a subject's susceptibility to an allergic reaction to an allergen, where the subject has no known allergy to the allergen, methods for measuring a response to challenge with a potential allergen in a whole blood sample obtained from a subject with known allergic reactivity to allergens other than the potential allergen; and an in vitro system for reliable detection or quantification of a specific white blood cell population in a whole blood sample are described.05-06-2010
20100161561METHOD AND SYSTEM FOR DATA ARCHIVING - Disclosed is a method and system for archiving data. A server computer (or any computing device) receives data transmitted over a network from a client computer, wherein at least some of the data was previously collected by a scientific instrument during an experiment. After receiving the data, the server computer updates (e.g., creates) an index for the received data, archives the received data, and automatically transmits a notification to the client computer that the received data has been archived.06-24-2010
20100209950GRANULOCYTE-BASED METHODS FOR DETECTING AND MONITORING IMMUNE SYSTEM DISORDERS - Methods are provided for determining a subject's susceptibility to an allergic reaction upon exposure to an offending allergen. Methods are also provided for determining and monitoring a subject's responsiveness to ongoing allergy treatment08-19-2010
20110014285N-ACETYL CYSTEINE COMPOSITIONS AND METHODS TO IMPROVE THE THERAPEUTIC EFFICACY OF ACETAMINOPHEN - The present invention relates to compositions for improving the efficacy of acetaminophen comprising a unit dose of acetaminophen and a therapeutic efficacy-enhancing amount of N-acetylcysteine, such that acetaminophen and N-acetylcysteine are present in the composition in a molar ratio of acetaminophen to N-acetyl cysteine ranging from about 1:15 to about 1:0.000977, and use of such compositions for analgesic and antipyretic applications.01-20-2011
20110029519Population clustering through density-based merging - A method and/or system for analyzing data using population clustering through density based merging.02-03-2011

Patent applications by Leonore A. Herzenberg, Stanford, CA US