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Leonardo
Leonardo Ajdelsztajn, Niskayuna, NY US
| Patent application number | Description | Published |
|---|---|---|
| 20100143620 | WETTING RESISTANT MATERIAL AND ARTICLES MADE THEREWITH - An article coated with a highly durable, wetting resistant coating is provided. The article comprises a coating that comprises a cermet material. The cermet material includes a nickel-bearing metal matrix and a phase disposed within the matrix. The phase includes an anion moiety, for example nitrogen, carbon, or boron; and a cation moiety, for example chromium, zirconium, titanium, vanadium, hafnium, niobium, or tantalum. The phase is present in the cermet at a level of at least about 5 volume %. | 06-10-2010 |
| 20100279022 | System and Method For Applying A Coating To A Substrate - A process for providing a protective layer to an article. The process includes depositing a layer of material onto a surface of the article with a thermal spray process. Examples of thermal spray process include high velocity oxygen/air fuel, atmospheric plasma spray, and chemical vapor deposition. Coating methods, such as cold vapor deposition and physical vapor deposition, may also be used. The layer can then be bonded to the article by heating material in the layer adjacent its connection with the article. Bonding the layer to the article can be performed by irradiating the layer with a collimated light source, the layer irradiation can be applied concurrently with the thermal spray process | 11-04-2010 |
| 20110086178 | CERAMIC COATINGS AND METHODS OF MAKING THE SAME - A method for forming a ceramic coating is provided. The method includes providing a slurry comprising a liquid and a plurality of feedstock particles disposed in the liquid, injecting the slurry into the flame of a thermal spray gun, and spraying the slurry on a surface of a substrate using the thermal spray gun to form the ceramic coating such that at least a part of the surface of the substrate is covered by the ceramic coating, wherein a thickness of the ceramic coating is in a range from about 10 nanometers to about 3 micrometers, and wherein a density of the ceramic coating is more than about 90 percent, and wherein the ceramic coating is a continuous coating. | 04-14-2011 |
| 20110126673 | RHENIUM RECOVERY FROM SUPERALLOYS AND ASSOCIATED METHODS - A method of recovering rhenium from rhenium-containing superalloy scrap is provided. The superalloy is usually a nickel-based superalloy. The method includes the steps of forming an oxidation feedstock of flaky morphology of the superalloy scrap, and oxidizing the oxidation feedstock to convert rhenium into a volatile rhenium oxide. The flaky morphology of the oxidation feedstock is achieved by increasing the surface area of the superalloy scrap. | 06-02-2011 |
| 20110293919 | Combustion Cold Spray - Different types of apparatus for fabricating a deposit, method of deposition and an article are presented. The apparatus include a thermal spray gun comprising a combustion chamber, combustion zone, an air injection port, a fuel injection port, a nozzle and a liquid injection port. The combustion zone exists between the inlet side and outlet side of the combustion chamber. The method includes, among other things, providing a fuel and an oxidizer inside the combustion zone, initiating combustion inside the combustion zone, and directing products of the combustion toward the outlet side to create a combustion product stream. The method also includes introducing a feedstock mixture comprising a feedstock material and a liquid into the combustion product stream to create an entrained feedstock stream, and expelling the entrained feedstock stream from the spray gun through a nozzle to form a deposit on a surface of the article. | 12-01-2011 |
| 20110305873 | COMPOSITION AND METHOD FOR APPLYING A PROTECTIVE COATING - A coating composition includes a cermet material having metal carbide phase particles with an average size of less than 5 microns. The coating has an average surface roughness of less than approximately 5 microns. A system for applying a coating to a substrate includes a spray gun configured for use with a high velocity oxygen or high velocity air fuel system. The system further includes a cermet material supplied to the spray gun, wherein the cermet material includes at least approximately 34 percent by weight of a metal carbide phase having an average particle size of less than or equal to approximately 5 microns. The metal carbide phase is dispersed in a liquid selected from the group consisting of water, alcohol, an organic combustible liquid, or an organic incombustible liquid. | 12-15-2011 |
Leonardo Altamore, Foxborough, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20090210814 | VISUALIZATION OF PROCESS CONTROL DATA - Graphical representations of operational process control data associated with monitored processes is displayed within the context of the geographical locations at which the processes operate, and in a manner as to model individual components of the processes. | 08-20-2009 |
Leonardo Amatori, Cary, NC US
| Patent application number | Description | Published |
|---|---|---|
| 20090010157 | FLOW CONTROL IN A VARIABLE LATENCY SYSTEM - A device and method for packet flow control is described. The method may comprise, at a packet sender device, adding a flow control identifier to a packet and transmitting a packet with the packet flow control identifier to a packet receiver device over a data path. Thereafter, the packet receiver device may receive, from the packet receiver device, flow control data that includes a received flow control identifier generated in response to the sent flow control identifier. The sent flow control identifier may then be compared with the received flow control identifier and a state of a receiver buffer at the receiver packet device may be estimated based on the comparison. In an example embodiment, at the packet sender device, a flow control instruction may be added to the packet to instruct the packet receiver device to enter a “no transmit” state. | 01-08-2009 |
Leonardo Arcuri Neto, Sao Paulo BR
| Patent application number | Description | Published |
|---|---|---|
| 20100074984 | BLOWING MOLD - To allow to increase the production capacity of conventional blow molding machines by using the space available within it, more specifically by using the available space in the direction of the nominal path of opening and closing the original distribution line for mold cavities of the blowing machine and through which it will be possible to increase the assembly in distribution lines for mold cavities, which will be located in parallel, in the direction of the nominal path of opening and closing the molds and, for that, the blowing mold as disclosed herewith incorporates an embodiment allowing joint displacement of equal side and intermediary halves composing mold cavities, so to neutralize the force tending to promote the opening of the halves of contiguous mold cavities, which is generated by the pneumatic pressure as introduced, by means of blowing pins, inside parisons which are located at the mold cavities, with no need to change the required compression force to keep closed the mold-bearing tables of the blowing machine. | 03-25-2010 |
| 20100180543 | SEALING SYSTEM FOR PACKAGE - Sealing system for package, created to avoid undesirable leakage and to enable to obtain a different and innovatively designed package, not effecting sealing performance, characterized by being constituted by a roll-on type package made of plastic material ( | 07-22-2010 |
Leonardo Badino US
| Patent application number | Description | Published |
|---|---|---|
| 20120109630 | TEXT-TO-SPEECH METHOD AND SYSTEM, COMPUTER PROGRAM PRODUCT THEREFOR - A text-to-speech system adapted to operate on text in a first language including sections in a second language, includes a grapheme/phoneme transcriptor for converting the sections in the second language into phonemes of the second language; a mapping module configured for mapping at least part of the phonemes of the second language onto sets of phonemes of the first language; and a speech-synthesis module adapted to be fed with a resulting stream of phonemes including the sets of phonemes of the first language resulting from mapping and the stream of phonemes of the first language representative of the text, and to generate a speech signal from the resulting stream of phonemes. | 05-03-2012 |
Leonardo Balletti, San Lazzaro Di Savena IT
| Patent application number | Description | Published |
|---|---|---|
| 20100012133 | Manufacturing Machine for Producing Combination Cigarette Filters - A manufacturing machine for producing combination filters for cigarettes, and having: a group-forming unit for forming groups of filter portions, each having at least two different filter portions aligned axially and contacting at the ends; a winding unit which receives a succession of groups of filter portions from the group-forming unit, winds a strip of wrapping material about the succession of groups of filter portions to form a continuous filter rod, and cuts the combination filters off the continuous filter rod by cyclically cutting the continuous filter rod transversely; and a transfer unit which transfers the groups of filter portions from the group-forming unit, in which the groups of filter portions travel transversely, to the winding unit, in which the groups of filter portions travel axially, and has at least one spider, which feeds the groups of filter portions successively into a forming beam of the winding unit, and at least one release drum which releases the groups of filter portions successively to the spider; the release drum being mounted to move between a work position, in which the release drum is adjacent and connected to the spider, and a maintenance position, in which the release drum is detached a good distance from the spider. | 01-21-2010 |
| 20100012135 | MANUFACTURING MACHINE FOR PRODUCING TOBACCO INDUSTRY ARTICLES - A manufacturing machine for producing tobacco industry articles, and having at least one station having a number of drums cooperating with one another to convey and process filter portions; and a supporting structure fitted to a frame and supporting the drums at the station. The station has a vertical front panel supporting at least some of the drums at the station and fixed removably to the supporting structure for replacement, together with the respective drums, when making a brand change. | 01-21-2010 |
Leonardo Blanga, Haifa IL
| Patent application number | Description | Published |
|---|---|---|
| 20100096535 | POSITION SENSOR - A position sensing device (PSD) comprising: a light source that provides light responsive to current that it receives; a power source that provides current to the light source through a load line; a photodetector that receives an amount of light from the light source that is a function of position of the light source relative to the photodetector; and an integrated circuit comprising an I/O port connected to the light source and having a plurality of selectable states; wherein different selectable states determine different values for the load line and therefore current provided to the light source. | 04-22-2010 |
Leonardo Bonilha, Charleston, SC US
| Patent application number | Description | Published |
|---|---|---|
| 20110077503 | Automatic MRI Quantification of Structural Body Abnormalities - Disclosed herein are methods and systems related to the body region analysis. In some forms, the analysis relates to body region abnormalities. In some forms, the methods and systems analyze and assign comparison scores (such as Z-score) to an image of a body region. In some forms, the comparison score is plotted voxel-by-voxel. In some forms, the computers and systems are adapted to execute the methods disclosed herein | 03-31-2011 |
Leonardo Borras, Zurich CH
| Patent application number | Description | Published |
|---|---|---|
| 20090028848 | SEQUENCE BASED ENGINEERING AND OPTIMIZATION OF SINGLE CHAIN ANTIBODIES - The invention provides methods of using sequence based analysis and rational strategies to modify and improve the structural and biophysical properties of single chain antibodies (scFvs), including stability, solubility, and antigen binding affinity. These methods and strategies can be used individually or in combination. The methods of the present invention also include the use of a database comprising scFv sequences from an experimentally screened scFv library of antibodies that have been selected to have superior solubility and stability. The invention also provides methods of using the properties found for these selected antibodies in a general approach for reshaping scFv antibodies to improve stability and solubility properties of a single chain antibody fragment. | 01-29-2009 |
| 20090074780 | METHODS OF MODIFYING ANTIBODIES, AND MODIFIED ANTIBODIES WITH IMPROVED FUNCTIONAL PROPERTIES - The invention provides methods of using sequence based analysis and rational strategies to modify and improve the structural and biophysical properties of immunobinders, and in particular of single chain antibodies (scFvs), including such properties as stability, solubility, and/or antigen binding affinity. The invention provides methods of engineering immunobinders, and in particular scFvs, by performing one or more substitutions at amino acid positions identified by analysis of a database of selected, stable scFv sequences, wherein preferred amino acid residues for substitution have been identified. The invention also provides immunobinders prepared according to the engineering methods of the invention. The invention also provides preferred scFv framework scaffolds, into which CDR sequences can be inserted, as well as scFv antibodies made using these preferred framework scaffolds. | 03-19-2009 |
Leonardo Borras, Schlieren CH
| Patent application number | Description | Published |
|---|---|---|
| 20100137150 | Sequence Based Engineering and Optimization of Single Chain Antibodies - The invention provides methods of using sequence based analysis and rational strategies to modify and improve the structural and biophysical properties of single chain antibodies (scFvs), including stability, solubility, and antigen binding affinity. These methods and strategies can be used individually or in combination. The methods of the present invention also include the use of a database comprising scFv sequences from an experimentally screened scFv library of antibodies that have been selected to have superior solubility and stability. The invention also provides methods of using the properties found for these selected antibodies in a general approach for reshaping scFv antibodies to improve stability and solubility properties of a single chain antibody fragment. | 06-03-2010 |
| 20110117091 | HUMANIZATION OF RABBIT ANTIBODIES USING A UNIVERSAL ANTIBODY FRAMEWORK - The present invention relates to an universal antibody acceptor framework and to methods for grafting non-human antibodies, e.g., rabbit antibodies, using a universal antibody acceptor framework. Antibodies generated by the methods of the invention are useful in a variety of diagnostic and therapeutic applications. | 05-19-2011 |
| 20110159007 | STABLE AND SOLUBLE ANTIBODIES INHIBITING TNF ALPHA - The present invention relates to particularly stable and soluble scFv antibodies and Fab fragments specific for TNF, which comprise specific light chain and heavy chain sequences that are optimized for stability, solubility, in vitro and in vivo binding of TNF, and low immunogenicity. Said antibodies are designed for the diagnosis and/or treatment of TNF-mediated disorders. The nucleic acids, vectors and host cells for expression of the recombinant antibodies of the invention, methods for isolating them and the use of said antibodies in medicine are also disclosed. | 06-30-2011 |
| 20110268728 | SOLUBILITY OPTIMIZATION OF IMMUNOBINDERS - The invention provides methods of using sequence based analysis and rational strategies to improve the solubility of immunobinders, and in particular of single chain antibodies (scFvs). The invention provides methods of engineering immunobinders, and in particular scFvs, by performing one or more substitutions with hydrophilic residues identified by analysis of a database of selected, stable scFv sequences. The invention also provides immunobinders with optimized solubility prepared according to the engineering methods of the invention. | 11-03-2011 |
| 20120014958 | STABLE AND SOLUBLE ANTIBODIES INHIBITING VEGF - The present invention relates to soluble and stable anti-VEGF immunobinders comprising CDRs from rabbit monoclonal antibodies. Said antibodies are designed for the diagnosis and/or treatment of VEGF-mediated disorders. The hybridomas, nucleic acids, vectors and host cells for expression of the recombinant antibodies of the invention, methods for isolating them and the use of said antibodies in medicine are also disclosed. | 01-19-2012 |
Leonardo Cadaddu, Crema IT
| Patent application number | Description | Published |
|---|---|---|
| 20100289324 | HYDRAULIC BRAKING DEVICE HAVING SECURITY PROVISIONS, FOR A FARM TRACTOR OR A SIMILAR VEHICLE - A braking system for farm tractors and similar vehicles, has a differential braking system and a hydraulic system for the braking assistance forming a system unit (H) which includes two circuit branches (H | 11-18-2010 |
Leonardo Canan-Haden Frias, Ciudad De La Habana CU
| Patent application number | Description | Published |
|---|---|---|
| 20080312139 | Use of Pharmaceutical Composition Containing Epidermal Growth Factor (EGF) for Diabetic foot Amputation Prevention - The invention relates to the use of Epidermal Growth Factor (EGF) in a preferably-Injectable pharmaceutical composition which is administered by means of infiltration into and around chronic cutaneous ischaemic lesions in order to prevent diabetic foot amputation. Said composition can be administered to recently-created surgical surfaces damaged by the effect of acute reperfusion with oxygenated blood following prolonged ischaemia, thereby preventing further surgical procedures and favouring the preservation of the extremity. The aforementioned composition can be used to improve (i) the cell microenvironment, thereby increasing the reparative and defensive capacity and viability of the is tissues and (ii) the cicatrisation of cutaneous ischaemic lesions, thereby stimulating cell proliferation. The invention is suitable for use in human, veterinary and experimental medicine, specifically in vascular angiology and surgery, dermatology, burn treatment and reconstructive surgery and geriatric medicine. Said composition can be used for recalcitrant ulcers which are associated with lesions in the macro and/or microvasculature, patients with inadequate lymphatic and/or venous return and ulcers or other lesions which are difficult to cicatrise and/or heal. | 12-18-2008 |
Leonardo Cappuccini, Rovereto (tn) IT
| Patent application number | Description | Published |
|---|---|---|
| 20110277942 | MACHINE FOR REGENERATION OF PNEUMATIC TYRES - There is described a machine ( | 11-17-2011 |
| 20120016522 | PROCESS AND MACHINE FOR IDENTIFICATION AND WORKING OF DEFECTS ON USED TYRES - An automatic process for the identification and working of defects ( | 01-19-2012 |
Leonardo Caseres, Helotes, TX US
| Patent application number | Description | Published |
|---|---|---|
| 20110259092 | Corrosion Sensor - A corrosion sensor may include a sensor body, a chloride probe held in the sensor body, a pH probe held in the sensor body, a reference electrode for the chloride probe and the pH probe held in the sensor body, a multiple array sensor held in the sensor body and a resistivity probe held in the sensor body. A method of measuring corrosion in a reinforced concrete structure may include inserting a corrosion sensor into a reinforced concrete structure and monitoring chloride ions with the chloride probe, pH with the pH probe, localized concrete resistivity with the resistivity probe and corrosion current density with the multiple array sensor. | 10-27-2011 |
Leonardo Cavanha Almeida, Sao Jose Dos Campos BR
| Patent application number | Description | Published |
|---|---|---|
| 20100084506 | AIRCRAFT RUDDER AUTHORITY CONTROL SYSTEM - A system that acts on a rudder (L) having its stop parts commanded or moved by an actuator (A) is described. The rudder system comprises a reversible mechanical system with movable stop parts working based on control/command signals, having stop parts (M, M′) inside of the field of movement of the actuator (A), interfering in the movement of said actuator; the mentioned control signals are based on informations of the aircraft such as traction of the engines or other signal from each engine (pressure, temperature or axis rotation speed); flight speed (“airspeed”); altitude; skidding angle; aircraft on the ground. The system limits the deflection of the rudder in flight with symmetrical traction, enough for normal maneuvers, and it allows total authority of the rudder (L), allowing a larger movement (larger deflection angle) just when necessary, in other words, when there is a traction asymmetry between the engines and, for aircrafts having wheels mechanically connected to the pedals and rudder, when they are maneuvering on the ground during taxi operations. | 04-08-2010 |
Leonardo Chen, Medford, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20100161779 | SYSTEM AND METHOD FOR PROVIDING QUALITY-REFERENCED MULTIMEDIA - A system and method for providing quality-referenced multimedia including a receiver configured to receive multimedia from at least one multimedia source, and one or more processors configured to generate a quality reference based on the multimedia, format the quality reference into an elementary stream, and associate the elementary stream with the multimedia to form quality-referenced multimedia. The system and method may also include a transmitter configured to transmit the quality-referenced multimedia for output at one or more output devices and one or more storage systems for storing the quality-referenced multimedia. | 06-24-2010 |
Leonardo Chicarella, Tagliacozzo IT
| Patent application number | Description | Published |
|---|---|---|
| 20100246036 | Preliminary Controlled Pre-Deformation Treatment for the Production of Mirrors - A method for the production of mirrors entails performing a preliminary controlled pre-deformation treatment of an optical system, consisting of the following phases: calculation of the deformation of the optical system due to a selected reflecting treatment; design of a deforming layer such as to produce on the optical system a deformation opposite to the one caused by the selected reflecting treatment; and deposition on the optical system of a deforming layer on which the selected reflecting treatment will subsequently be deposited. | 09-30-2010 |
Leonardo Chiezzi, Follonica (grosseto) IT
| Patent application number | Description | Published |
|---|---|---|
| 20090281246 | PROCESS FOR THE PREPARATION OF HIGH IMPACT VINYLAROMATIC (CO)POLYMERS GRAFTED ON AN ELASTOMER - A process for the preparation of vinylaromatic (co)polymers grafted on an elastomer comprising a rigid matrix consisting of vinylaromatic polymers or copolymers and of an elastomeric phase dispersed in the matrix in form of particles with a strictly bimodal distribution which comprises the functionalization of a first elastomeric fraction by means of a catalytic system containing a stable free radical initiator and subsequently the polymerization of the thus obtained mixture also in presence of a second non functionalized elastomeric fraction. | 11-12-2009 |
| 20100305264 | SEMI-CONTINUOUS INTEGRATED PROCESS FOR THE PRODUCTION OF HIGH IMPACT VINYL AROMATIC (CO)POLYMERS BY ANIONIC/RADICAL POLYMERIZATION IN SEQUENCE - Butadiene is anionically polymerized (or block copolimerized with styrene) in a low-boiling non-polar solvent in presence of rganolithiura compounds. At the end of the polymerization, the non-polar solvent is switched with styrene and the new solution is stored in tanks in relation to the type of polybutadiene (or its block copolymer with styrene) obtained. The polybutadiene solution (and/or its block copolymer with styrene) with the desired set of properties is then fed to a production plant of high impact vinyl aromatic (co) polymers. | 12-02-2010 |
Leonardo Chiezzi, Curtatone (mantova) IT
| Patent application number | Description | Published |
|---|---|---|
| 20110207884 | PROCESS FOR THE SYNTHESIS OF FUNCTIONALIZED POLY (1,3- ALKADIENES) AND USE THEREOF IN THE PREPARATION OF HIGH IMPACT VINYL AROMATIC POLYMERS - Process for the preparation of vinyl aromatic (co) polymers grafted on an elastomer in a controlled manner, comprising: dissolving an elastomer functionalized with bromoalkanes and nitroxy radicals, soluble in non-polar solvents, in a liquid phase consisting of a mixture of vinyl aromatic monomer (s)/polymerization solvent; feeding at least one radical initiator to the mixture, containing the functionalized elastomer in solution, and polymerizing the mixture thus obtained at a temperature higher than or equal to 1200C; recovering the vinyl aromatic (co) polymer obtained after devolatization; and recycling the solvent/monomer (s) mixture, coming from the devolatization, to step (a). | 08-25-2011 |
Leonardo Civale, Los Alamos, NM US
| Patent application number | Description | Published |
|---|---|---|
| 20100022397 | METHOD FOR IMPROVING PERFORMANCE OF HIGH TEMPERATURE SUPERCONDUCTORS WITHIN A MAGNETIC FIELD - The present invention provides articles including a base substrate including a layer of an oriented cubic oxide material having a rock-salt-like structure layer thereon; and, a buffer layer upon the oriented cubic oxide material having a rock-salt-like structure layer, the buffer layer having an outwardly facing surface with a surface morphology including particulate outgrowths of from 10 nm to 500 run in size at the surface, such particulate outgrowths serving as flux pinning centers whereby the article maintains higher performance within magnetic fields than similar articles without the necessary density of such outgrowths. | 01-28-2010 |
| 20100026292 | METHOD AND APPARATUS FOR MEASURING MAGNETIC ANISOTROPY OF A CONDUCTIVE WIRE OR TAPE - A method and apparatus for measuring the magnetic field anisotropy of critical currents in conductive wires and conductive tapes having lengths of at least one meter. In one embodiment, the method and apparatus are adapted to measure the magnetic field anisotropy of critical currents in superconducting wires and tapes. The apparatus includes a magnetic field generation assembly that is capable of generating a magnetic field. The magnetic field is orthogonal to a current passing through a conductive wire or conductive tape positioned on an axis of the assembly. The magnetic field generation assembly and magnetic field are rotatable about the axis. | 02-04-2010 |
Leonardo Dalloro, Bollate-Milano IT
| Patent application number | Description | Published |
|---|---|---|
| 20110092746 | PROCESS FOR THE PREPARATION OF PHENOL - A process is described for the preparation of phenol by the hydrodeoxygenation of polyhydroxylated benzene derivatives or by the selective hydroxylation of benzene under depletive conditions, characterized in that the above-mentioned reactions are carried out in the presence of a catalyst based on multi component metal oxides comprising at least one metal selected from the groups VB, VIB, VIII, IB, IIB, IVA, VA. | 04-21-2011 |
Leonardo De Silva Munoz, Toulouse FR
| Patent application number | Description | Published |
|---|---|---|
| 20090294282 | WATER ELECTROLYSIS DEVICE - Electrolysis device intended to produce hydrogen by the reduction of water, comprising a cathode compartment, an anode compartment, and an element connecting said compartments and allowing ions to migrate between them, | 12-03-2009 |
Leonardo Diaferia, Ruvo Di Puglia (bari) IT
| Patent application number | Description | Published |
|---|---|---|
| 20110029129 | ROBOTIZED SYSTEM FOR POSITIONING A PATIENT WITH RESPECT TO AT LEAST ONE PARTICLE SOURCE - A robotized system ( | 02-03-2011 |
Leonardo Di Nunno, Bari IT
| Patent application number | Description | Published |
|---|---|---|
| 20090181970 | Functionalized diarylisoxazoles inhibitors of ciclooxygenase - The present invention refers to isoxazole derivatives, in particular diarylisoxazole derivatives inhibitors of cyclooxygenase (COX), in particular cyclooxygenase-1 (COX-1), to their pharmaceutical compositions, the process for their preparation and their use for the chemoprevention and treatment of inflammatory syndromes and in the prevention and treatment of carcinomas, in particular intestinal, ovarian and cutaneous carcinomas, in the treatment of pain syndromes, in particular after surgery, and in the cardiovascular field as antithrombotics/vasoprotectives/cardioprotectives. | 07-16-2009 |
Leonardo Dondelli, Botticino/brescia IT
| Patent application number | Description | Published |
|---|---|---|
| 20090246727 | PHANTOM - The referencing or calibration phantom ( | 10-01-2009 |
Leonardo Finizole E Silva, Antwerp BE
| Patent application number | Description | Published |
|---|---|---|
| 20080261592 | METHOD TO IMPROVE THE REGISTRATION OF | 10-23-2008 |
Leonardo Foschi, San Miniato (pisa) IT
| Patent application number | Description | Published |
|---|---|---|
| 20120026840 | WRISTWATCH - A wristwatch comprising a case ( | 02-02-2012 |
Leonardo Fusi, Montespertoli IT
| Patent application number | Description | Published |
|---|---|---|
| 20090138128 | LOCAL DIGITAL VALVE CONTROLLER UNIT - A controller assembly is adapted for regulating at least one valve having a valve positioner. The controller assembly comprises a digital controller having a plurality of data inputs and data outputs and includes at least one proportional-integral-derivative (PID) controller operative to modulate the valve positioner in response to data received at the data inputs. The digital controller is configured to perform the following functions within a total time period of no greater than 10 ms: acquisition of data at the data inputs, processing of the data, and transmission of data from the data output in order to regulate the valve(s). The digital controller may include a quantity of at least sixteen digital inputs, at least sixteen digital outputs, at least eight analog inputs and at least eight analog outputs. | 05-28-2009 |
Leonardo Gaete, Santiago CL
| Patent application number | Description | Published |
|---|---|---|
| 20100310690 | Pharmaceutical product and analysis model for hormone replacement therapy for women and prevention of some cancers and uterine myomas - The present disclosure describes a study of estrogenic activity present in various plant species, selectively inducing some but not all estrogenic responses in the uterus. Prepubertal female rats were treated sequentially with various extracts or decoctions of different plant species or its vehicle, followed 1 h later by treatment with estradiol-17β (E) or its solvent. Uteri were excised under anesthesia and histologically processed for eosinophil quantification and morphometric evaluation of various uterine responses to estrogen, at 6 or 24 h after hormone or vehicle treatment. Besides extracts or decoctions, pure phytoestrogens were also used. Additionally, human mammary cancer cells MCF-7 or MDAMB-231 were cultured in presence of the extract (or decoction), E, both or solvent and cell proliferation was evaluated. Various extracts or decoction displayed selective estrogenic and/or antiestrogenic action for some but not all parameters of estrogen stimulation in the uterus and inhibited growth of human mammary cells in culture or antagonized the estrogen-induced increase in their growth. Present results reveal, for the first time, a dissociation of responses to estrogen by phytoestrogens, suggesting its possible therapeutic application as estrogenic compounds not inducing cell proliferation and reveal the anticancerous effect of some of the extracts with possible therapeutic relevance. The dissociation of responses to estrogen additionally suggest therapeutic applications in estrogen-related diseases (for instance, premenstrual syndrome, endometriosis, etc.); the inhibition of eosinophil degranulation suggest an application in diseases related to eosinophils (hypereosinophilic syndrome, allergic and hypersensitivity diseases). | 12-09-2010 |
Leonardo Hidd Fonteles, Nice FR
| Patent application number | Description | Published |
|---|---|---|
| 20110235719 | METHOD FOR TREATING DIGITAL DATA - The disclosure relates to a method for treating digital data, including a quantification step of calculating, in a space of dimension d, at least one vector index I | 09-29-2011 |
Leonardo Jordá Quilis, Valencia ES
| Patent application number | Description | Published |
|---|---|---|
| 20110224290 | COMBINE USE OF PTEROSTILBENE AND QUERCETIN FOR THE PRODUCTION OF CANCER TREATMENT MEDICAMENTS - The invention relates to the combined use of pterostilbene and quercetin for the production of cancer treatment medicaments. The in vitro growth of melanoma cells B16-F10 (B16M-F10) is inhibited (56%) by combined exposures of short duration (60 min/day) to PTER (40 μM)+QUER (20 μM) (˜average values of plasma concentrations measured within the first hour following the IV administration of 20 mg of each polyphenol/kg ˜). The combined intravenous administration of PTER+QUER (20 mg/kg×day) to mice inhibits (73%) the metastatic growth of melanoma B16M-F10 in the liver, a common site for metastasis development. The invention demonstrates that the combination of PTER+QUER inhibits the growth of malignant melanoma metastasis and prolongs the survival of the carrier host. | 09-15-2011 |
Leonardo Lecce, Napoli IT
| Patent application number | Description | Published |
|---|---|---|
| 20100019096 | ACTUATOR DEVICE BASED ON A SHAPE MEMORY ALLOY, AND A WING FLAP ASSEMBLY FITTED WITH SUCH AN ACTUATOR DEVICE - A wing-flap assembly includes a flap made up of a plurality of flap sections, in which each flap section is connected to the preceding one in a rotatable manner, and one or more actuator devices adapted to control the rotation of the flap sections. Each actuator device includes an extended element made of shape memory alloy and an arch-shaped framework made of elastic material, to which the extended element is fixedly connected under tension. Each end of the extended element is fixed to a respective end of the arch-shaped framework. At least one of the actuator devices is connected at one end to the first of the flap sections, and on the other side it is adapted to be connected to a wing structure. | 01-28-2010 |
Leonardo Maccari, Firenze IT
| Patent application number | Description | Published |
|---|---|---|
| 20090217033 | Short Authentication Procedure In Wireless Data Communications Networks - In a wireless communications network including at least one authenticator and at least one authentication server, wherein the authenticator is adapted to interact with the authentication server for authenticating supplicants in order to conditionally grant thereto access to the wireless communications network, a short authentication method for authenticating a supplicant, the method including: providing a shared secret, shared by and available at the supplicant and the authentication server; having the supplicant provide to the authenticator an authentication token, wherein the authentication token is based on the shared secret available thereat; having the authenticator forward the authentication token to the authentication server; having the authentication server ascertain an authenticity of the received authentication token based on the shared secret available thereat; in case the authenticity of the authentication token is ascertained, having the authentication server generate a first authentication key based on the shared secret available thereat, and provide the generated authentication key to the authenticator; having the supplicant generate a second authentication key based on the shared secret; and having the supplicant and the authenticator exploit the generated first and the second keys for communicating with each other. The short authentication method is particularly useful in situations of handoff of the supplicant from an authenticator to another. | 08-27-2009 |
Leonardo Maestri Texeira, Ithaca, NY US
| Patent application number | Description | Published |
|---|---|---|
| 20100112549 | Microorganism Detection Method and Apparatus - Embodiments of the present invention relate to selective organism detection, and, more particularly to recombinant bacteriophages and the use of such recombinant bacteriophages to detect target bacteria and to detect specific nucleic acid sequences within said target bacteria thus allowing for the detection of phenotypic characteristics of said bacteria such as determining drug(s) to which such target bacteria are resistant. The present invention further relates to sample preparation apparatuses for preparing samples for detection and analysis using bacteriophage-based techniques, that are low in cost, easy to use, and do not require technical expertise or any additional laboratory infrastructure to perform. | 05-06-2010 |
Leonardo Malcovati, Lyngby DK
| Patent application number | Description | Published |
|---|---|---|
| 20110160634 | CANKER SORE PATCH - An oral mucoadhesive patch used for canker sore treatments disclosed, said patch comprising a mucoadhesive layer and a protective layer, wherein the protective layer comprises pressure sensitive adhesive. | 06-30-2011 |
| 20120123442 | ADHESIVE PATCH WITH ENZYME - An adhesive patch for the removal or thinning of keratinaceous tissue comprising a backing layer covered on one side by an adhesive layer and an enzyme material comprising salmon zonase. The enzyme material selectively attacks the keratin, but not living cells. | 05-17-2012 |
Leonardo Mancari, Lemont, IL US
| Patent application number | Description | Published |
|---|---|---|
| 20080252009 | Method and layout for a craps game - The invention includes methods of playing craps. Point 7 and/or 7 Point 7 wagering area(s) are provided. Bets are placed on the areas. A come out roll is performed. A subsequent roll is performed if the come out roll does not terminate the round, and a payout is awarded to players who placed Point 7 wagers if the come out roll is a point and the subsequent roll is a 7. The invention includes awarding a payout to players who participated in the 7 Point 7 wager if the come out roll is a 7. The invention further includes performing a subsequent roll immediately following the come out roll, if the come out roll does not terminate the round, and awarding a payout to each player who participated in the 7 Point 7 wager if the come out roll is a point and the subsequent roll is a 7. | 10-16-2008 |
| 20080252010 | Method and layout for a craps game - The invention includes methods of playing craps. Wagering area(s) are provided. Bets are placed on the areas. A come out roll is performed. Subsequent rolls are performed if the come out roll does not terminate the round, and a payout is awarded to players who placed Point 7 wagers if the come out roll is a point and the subsequent roll is a 7. An embodiment includes a 7 roll followed by a point roll. A payout is made to players who placed a 7 Point 7 wager if the come out roll is a 7. If the come out roll does not terminate the round, a payout is awarded to players who participated in the 7 Point 7 wager if the next come out roll is a point and the subsequent roll is a 7. | 10-16-2008 |
| 20100009744 | Method and System for a Casino Game Providing a Repetitive Event Wager - In a casino game, such as Roulette, players are offered the ability to place a repetitive event wager that the same event will occur consecutively a particular number of times in a row. In the example of Roulette, before the roulette wheel is spun, a player places a repetitive event wager. The roulette wheel is then spun, and the ball lands on a particular pocket. If the event did not occur as a result of the spin, the repetitive event wager is over, and the player loses the wager. If the event did occur, the process is repeated. Ultimately, if the event occurs the particular number of times in a row, the player is paid a payout of a predetermined multiple of the amount of the repetitive event wager. | 01-14-2010 |
Leonardo Mangeruca, Genova IT
| Patent application number | Description | Published |
|---|---|---|
| 20100131801 | ELECTRONIC SYSTEM FOR DETECTING A FAULT - An electronic adapter device and an electronic system that comprises the electronic adapter device are described. The electronic adapter device comprises a device and a redundant device able to receive data from a first plurality of electronic devices and redundant data from a second plurality of electronic devices, and able to select therefrom first data and first redundant data respectively. The electronic adapter device also comprises a controller able to receive the selected first data and the selected first redundant data and is able to generate therefrom an error signal indicating a fault in an electronic device of the first plurality or a fault in the device. | 05-27-2010 |
Leonardo Marcovitz, South Miami, FL US
| Patent application number | Description | Published |
|---|---|---|
| 20090098522 | System for Simulation and Teaching Medical Care - The present invention is a system and method for simulating portable medical diagnostic instrument where an instructor interface is configured to communicate simulated medical information to simulated portable medical diagnostic instrument for teaching purposes to allow a trainee to read the simulated information on the simulated medical diagnostic instrument in a simulated real life environment. | 04-16-2009 |
Leonardo Maschio, Neuquen Capital AR
| Patent application number | Description | Published |
|---|---|---|
| 20090038799 | System, Method, and Apparatus for Combined Fracturing Treatment and Scale Inhibition - A treatment fluid for a subterranean formation includes a carrier fluid and an amount of particles including a granular scale inhibitor. The carrier fluid includes a hydratable gel fluid, a crosslinked gel fluid, an acid-based fluid, an oil-based fluid, and/or a visco-elastic surfactant. The particles include a proppant impregnated with the scale inhibitor, a solid particle formed largely from the scale inhibitor, or both. The proppant includes scale inhibitor adsorbed on porous surfaces within the proppant, and/or a porous proppant with scale inhibitor embedded in the bulk porosity of the proppant. The scale inhibitor is present in an amount between about 1% and 5% of a total weight of particles. The particles include scale inhibitor at a sufficient concentration and dissolution rate to provide acceptable scale inhibitor concentrations in produced fluids for production volumes exceeding 500 pore volumes. | 02-12-2009 |
Leonardo Muffatti, Montagna Di Valtellina (so) IT
| Patent application number | Description | Published |
|---|---|---|
| 20100224686 | APPARATUS AND METHOD FOR OBTAINING A RANDOM CODE USEABLE IN A DEVICE FOR UNIQUE IDENTIFICATION OF A PRODUCT - The present invention refers to a method and to an apparatus for obtaining a random code useable in a device for unique identification of a product wherein the apparatus comprises a sliding path of a continuous strip arranged along which is at least one drilling station for obtaining a plurality of holes on the strip, the plurality of holes forming the random code and it is wherein the drilling station is of the random type generating a plurality of holes according to a random and deterministically irreproducible process. | 09-09-2010 |
Leonardo Nappi, London GB
| Patent application number | Description | Published |
|---|---|---|
| 20110315153 | Smoking Articles and Method for Manufacturing Smoking Articles - The invention relates to a method of manufacturing a plurality of smoking articles, comprising providing a wrapping paper having a permeability of less than 15 CU and applying a burn retardant additive material in a predetermined pattern to the wrapping paper. The wrapping paper is wrapped about a tobacco material to form a wrapped rod and the wrapped rod is cut to form the plurality of smoking articles. The invention also relates to a smoking article manufactured by the method, wherein the wrapping paper has a permeability of less than 15 CU in areas without the burn retardant additive and a lower permeability in areas where the additive is applied. | 12-29-2011 |
Leonardo Panettieri, Pisa IT
| Patent application number | Description | Published |
|---|---|---|
| 20120128902 | Coated Printing Substrate - A coated printing substrate, preferably for offset or inkjet printing, comprises a coating composed of a water eraulsifiable binder, calcium carbonate or sulphate, a granular material of the grain size of a flour or a fine sand, and water. BGy a proper production method can be obtained a product which can be produced at industrial level with low costs and it is particularly suitable for the reproduction of photos or art pieces such as paintings or frescos as it gives the visual and tactile sensations of such kinds of art pieces, allowing, at the same time, high quality printing. | 05-24-2012 |
Leonardo Querzoni, Roma IT
| Patent application number | Description | Published |
|---|---|---|
| 20110276633 | METHOD AND SYSTEM FOR DATA MANAGEMENT IN PEER-TO- PEER NETWORK - A method for managing storage of data objects in a peer-to-peer system including a plurality of peer entities is provided. For each data object to be stored into the peer-to-peer system, the method including establishing a group of peer entities so that the group meets a stability requirement according to predetermined stability rules, storing the data object into each peer entity of the group, and each peer entity of the group generating and maintaining a group list associated with the data object, which includes the peer entities of the group. | 11-10-2011 |
Leonardo Rabaglia, Parma IT
| Patent application number | Description | Published |
|---|---|---|
| 20080251615 | DRUG ACTIVATION PROCESS AND VIBRATIONAL MILL THEREFOR - The invention comprises a process for activating drugs by means of high-energy co-grinding of the drug with a pharmaceutical carrier, characterised by the use of a vibrational mill equipped with means that regulate the vibration frequency. The process, performed by modifying the frequency of vibration and keeping its amplitude constant, produces drug/carrier composites with a constant particle size in which the degree of drug activation increases in proportion to the frequency applied. The invention also includes a vibrational mill suitably modified to perform the process described. | 10-16-2008 |
| 20110020442 | Taste Masked Oral Composition of Telithromycin - The invention relates to an oral compositions comprising telithromycin that have taste masking properties, a process for the preparation thereof, and methods of using the composition. | 01-27-2011 |
Leonardo Rescio, Corigliano D'Otranto IT
| Patent application number | Description | Published |
|---|---|---|
| 20090304870 | FOOD SUPPLEMENT BASED ON BIOLOGICALLYCOPENE AND PROCESS TO OBTAIN BIOLOGICAL LYCOPENE - Innovative food supplement based on biological lycopene, which is the bulk product, i.e. the total extract, obtained by treating with supercritical carbon dioxide a suitable extraction matrix, made by 50% biological tomato berries and 50% biological dry fruits (almonds, nuts and the like) and/or other components, following a co-extractive technology. Tomato berries are conveniently de-hydrated, milled and riddled; the co-extraction matrix (dry fruits, vegetables, others) is conveniently de-hydrated and milled. The obtained total extract is directly used for preparing lycopene based food supplements, without any modification or additivation. With respect to the known commercial food supplement, based on lycopene, such biological lycopene has unique quality features: the total extract is 100% natural; absence of chemical solvents; lycopene concentration in the final natural formula (not artificial); absence dosing problems and contra-indications. In the final product, lycopene is mixed with other natural anti-oxidants, co-extracted from the used vegetables. The boxing up of the bulk product (total extract) is made in soft or hard caps in several shapes and colours or in tablets or in other way (e.g. liquid, others). | 12-10-2009 |
Leonardo Scapozza, Grens CH
| Patent application number | Description | Published |
|---|---|---|
| 20100204219 | AROMATIC 1,4-DI-CARBOXYLAMIDES AND THEIR USE - The invention relates to novel compounds of formula (I) wherein X, Y, Z represent independently from one another C or N, n stands for 1, 2, 3, m is 0 or 1, p stands for 0 or an integer from 1 to 6, R | 08-12-2010 |
| 20100249135 | SULFONAMIDES AND THEIR USE AS A MEDICAMENT - The present invention relates to the use of a sulfonamide compound of formula (I): wherein R | 09-30-2010 |
| 20110112110 | ANTIPROLIFERATIVE COMPOUNDS AND THERAPEUTIC USES THEREOF - Inhibitors of the oncogenic tyrosine kinase ALK and of the Bcr-Abl mutant T315I Bcr-Abl, pharmaceutical compositions containing the same and their use for the treatment of hyper-proliferative diseases. | 05-12-2011 |
| 20110281862 | ALFA-CARBOLINE INHIBITORS OF NPM-ALK, RET, AND BCR-ABL - The present invention relates to compounds of formula (I) | 11-17-2011 |
Leonardo Serpa, Zurich CH
| Patent application number | Description | Published |
|---|---|---|
| 20080278977 | Method for operating a converter circuit, and device for carrying out the method - A method for operating a converter circuit is specified with the converter circuit having a converter unit with a multiplicity of controllable power semiconductor switches and having an energy storage circuit formed by two series-connected capacitors, in which the controllable power semiconductor switches are controlled by means of a control signal formed from a hysteresis signal vector (x), and the hysteresis signal vector (x) is formed from a difference-phase connection current vector (Δi | 11-13-2008 |
| 20090237964 | METHOD FOR OPERATING A CONVERTER CIRCUIT AND APPARATUS FOR IMPLEMENTING THE METHOD - A method is disclosed for the operation of a converter circuit, wherein the converter circuit has a converter unit having a multiplicity of actuatable power semiconductor switches and an LCL filter which is connected to each phase connection of the converter unit, in which the actuatable power semiconductor switches are actuated by means of an actuation signal (S) formed from a hysteresis active power value (d | 09-24-2009 |
Leonardo Tognarelli, Firenze IT
| Patent application number | Description | Published |
|---|---|---|
| 20100070203 | METHOD FOR DETERMINING REHEAT CRACKING SUSCEPTIBILITY - System, computer software and method for determining a susceptibility to reheat cracking of a sample of material, which includes a welded area. The method includes measuring a length of the sample, applying a first stress to the sample to achieve a predetermined elongation of the sample, exposing the elongated sample to a predefined heat treatment, applying a second stress to the sample until the sample breaks at least into two different pieces, and determining the susceptibility of the broken sample to reheat cracking. | 03-18-2010 |
| 20110137616 | Design Method for Subsea Equipment Subject to Hydrogen Induced Stress Cracking - Systems and methods for generating transfer functions associated with calculating local stresses on pipe elements by post processing forces and moments of a pipe model representing the piping system. The transfer functions are reusable and allow recalculation with different sets of user data without requiring regeneration of the transfer functions. | 06-09-2011 |
Leonardo Urbiola Soto, Queretaro MX
| Patent application number | Description | Published |
|---|---|---|
| 20090158783 | HYDRODYNAMIC BALANCE RING FOR CENTRIFUGAL ROTATION MACHINES - A balance ring for washing machine devices as may be used in vertical and horizontal axis washing machines is provided. One structural arrangement of the ring comprises alternatively disposed positive and negative curved blades, as well as curved and straight blades, that in combination with the different heights of the blades, reduce the time and the amplitude of the vibrations of the transition state, thus enabling the washing basket to spin at higher velocities, and reducing the centrifugal cycle while increasing the centrifugal force applied to the objects being washed. Such an structural arrangement provides a superior drying of the clothes and further results in energy savings. | 06-25-2009 |
| 20110048081 | BALANCE RING SYSTEM ON TWO PLANES FOR A SPIN ROTARY MACHINE - A textile washing machine has a rotary basket balanced in at least one of its two planes, where optionally a first balance ring is structurally formed at the lower part of the basket or bottom of basket in order to balance the lower plane of the rotary basket and/or optionally, a second balance ring structured at the upper part of the basket. The first balance ring comprises: a channel or track that forms an integral part with the bottom of basket, a viscous drag fluid lodged in the track, a plurality of spheres lodged in the channel or track, immerse in the viscous drag fluid, and a lid that seals hermetically against the track. The lid comprises at least one radial rib in order to provide the bottom of basket with a structural reinforcement so that the bottom of basket does not weaken due to the presence of the track or channel. The second balance ring includes: a base with a first wall and a second wall, a cover that closes the base and with the same walls of the base, a working fluid lodged in the base, at least a curved blade lodged in the base where the blade covers from the first wall of the base and leaves a clearing between the blade and second wall, allowing the working fluid to have a vertical component; and at least a straight blade lodged in the base and alternated with the at least one aforementioned curved blade. | 03-03-2011 |
Leonardo Vainsencher, San Jose, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20080225957 | Dynamic packet size control for MPEG-4 data partition mode - A dynamic AC prediction technique is implemented in a data partition mode which automatically disables AC prediction for encoding the current macroblock in the next packet when packet overflow occurs. Otherwise, when there is no overflow, AC prediction remains enabled to maintain compression efficiency. More particularly, in the preferred embodiment, a determination is first made whether a macroblock causes a packet overflow if it is encoded in the current packet. If so, a new packet is initiated into which the macroblock is encoded without AC prediction as the first macroblock. Otherwise, the macroblock with AC prediction remains in the current packet and a new macroblock is encoded. | 09-18-2008 |
Leonardo Vainsencher, Tel-Aviv IL
| Patent application number | Description | Published |
|---|---|---|
| 20090160552 | APPARATUS AND METHOD FOR CLASS D AMPLIFIER WITH SAMPLING RATE CONVERSION - A class D amplifier is provided. The class D amplifier includes an interpolator, a sampling rate converter, a pulse width modulator, a sigma-delta modulator, and a pulse width modulation (PWM) pulse generator (PPG). The sampling rate converter interpolates the output of the interpolator such that the sampling rate converter up-samples the interpolator output by a factor that is greater than one and less than two. The pulse width modulator outputs a multi-bit digital signal. The sigma-delta modulator performs sigma-delta modulation on the pulse width modulator output, the order of the sigma-delta modulation is programmable, and the output of the sigma-delta modulator is a multi-bit, digital signal. At least one of the orders to which the sigma-delta modulator can be programmed is greater than two. The PPG provides a pulse signal such that the width of each pulse is based on the value of the sigma-delta modulator output. | 06-25-2009 |
Leonardo Velasco Varo, Cordoba ES
| Patent application number | Description | Published |
|---|---|---|
| 20090138993 | Sunflower seeds with high delta-tocopherol content - The present invention relates to sunflower seeds which have been genetically modified through two artificial induction cycles of mutations followed in each case by processes for the identification of mutant individuals which have the desired character. The disclosed seeds are characterised in that they contain between 26% and 80% of the tocopherols as delta-tocopherol. This high delta-tocopherol production is determined by the genotype of the seeds which have been modified to this effect, and is always obtained independently of the culture conditions, thereby obtaining an inheritable character. Today, sunflower seeds producing such high levels of delta-tocopherol do not exist. Genetically modified sunflower plants which produce through self-fertilisation seeds with high delta-tocopherol levels and the oil with high natural delta-tocopherol concentration, extracted from the seeds, are also objectives of the present invention. | 05-28-2009 |
| 20110061138 | Sunflower Oil with High Heat Stability - The invention relates to a sunflower oil with high heat stability, which is characterised in that between 15% and 45% of the fatty acid total are saturated fatty acids (palmitic acid and stearic acid), between 45% and 75% of the fatty acid total is oleic acid and more than 85% of the tocopherol total corresponds to the sum of gamma-tocopherol and delta-tocopherol. The invention also relates to sunflower seeds that contain an oil with the aforementioned characteristics and sunflower plants which as a result of self-pollination produce seeds with the aforementioned characteristics. In addition, the invention relates to the use of said oil in food and animal feed and for the formulation of biolubricants and biofuels. | 03-10-2011 |