Patent application number | Description | Published |
20110097286 | COMPOSITIONS AND METHODS FOR INHIBITING PAR2 ACTIVATION OF KERATINOCYTES - A composition for inhibiting PAR2 activation of keratinocytes is disclosed as comprising a vitamin B3 compound, an N-acyl amino acid compound, and a | 04-28-2011 |
20110166370 | Scattered Branched-Chain Fatty Acids And Biological Production Thereof - Methods and cells for producing scattered branched-chain fatty acids are provided. For example, the invention provides a method for producing branched-chain fatty acid comprising a methyl on one or more even number carbons. The method comprises culturing a cell comprising an exogenous or overexpressed polynucleotide comprising a nucleic acid sequence encoding a polypeptide that catalyzes the conversion of propionyl-CoA to methylmalonyl-CoA and/or an exogenous or overexpressed polynucleotide comprising a nucleic acid sequence encoding a polypeptide that catalyzes the conversion of succinyl-CoA to methylmalonyl-CoA, under conditions allowing expression of the polynucleotide(s) and production of branched-chain fatty acid. The cell produces more branched-chain fatty acid comprising a methyl on one or more even number carbons than an otherwise similar cell that does not comprise the polynucleotide(s). A cell that produces branched-chain fatty acid and the branched-chain fatty acid also are provided. | 07-07-2011 |
20110262025 | Cosmetic Compositions and Methods for Maintaining and Improving Barrier Function of the Stratum Corneum and to Reduce the Visible Signs of Aging in Skin - Gene panels, biomarker panels and microarrays relating to lipid formation in stratum corneum of human skin as a function of extrinsic and/or intrinsic aging conditions, and methods for assessing the age status of human skin, methods for identifying or evaluating an agent as effective for improving stratum corneum barrier maintenance and/or repair properties in aged skin, and cosmetic composition comprising the identified agents are all provided. | 10-27-2011 |
20120148510 | Compositions and Methods for Improving the Appearance of Facial Pores - A method of improving the appearance of facial pores is provided. The method includes the step of applying a composition having an effective amount of a material that regulates IL-1 and/or hyaluronic acid synthesis to an area of facial pores, wherein the composition is applied for a period of time sufficient for the material to improve the appearance of the facial pores. In some embodiments, the material that regulates IL-1 and/or hyaluronic acid synthesis is hexyldecanol. The method may also include the step of identifying facial pores on a facial skin surface. | 06-14-2012 |
20120148515 | Cosmetic Compositions and Methods for Inhibiting or Reducing Trypsin Activity - A cosmetic composition formulated for topical application to skin is provided. The composition includes a safe and effective amount of cyclohexane-1,2,3,4,5,6-hexyl; a safe and effective amount of an N-acyl amino acid compound; and a dematologically acceptable vehicle. | 06-14-2012 |
20120156146 | Compositions and Methods for Improving the Appearance of Facial Texture - A method of improving the appearance of facial texture may comprise the step of applying a composition comprising an effective amount of a material that regulates hyaluronic acid synthesis to an area of textured facial skin, wherein the composition is applied for a period of time sufficient for the material to improve the appearance of the facial texture. In some embodiments, the material that regulates hyaluronic acid synthesis is hexyldecanol. The method may also include the step of identifying facial texture on a facial skin surface. In particular embodiments, the facial skin texture is selected from the group consisting of macro-texture, micro-texture, and combinations thereof. | 06-21-2012 |
20120197016 | SCREENING METHODS OF MODULATING ADRENERGIC RECEPTOR GENE EXPRESSIONS IMPLICATED IN MELANOGENESIS - Embodiments of screening methods for determining test agents effective for modifying the appearance of pigmented skin are provided. The screening method may comprise the steps of contacting a cell, a cell culture, or bulk cells with the test agent, wherein the cell, the cell culture, or the bulk cells comprise ADRβ1 receptors, and determining based on the binding interaction of the test agent with the ADRβ1 receptors whether the test agent is an effective ADRβ1 receptor antagonist suitable for modifying the appearance of pigmented skin, wherein a test agent is considered to be an effective ADRβ1 receptor antagonist when it defines a half maximal inhibitory concentration of less than about 1000 ppm. | 08-02-2012 |
20120201768 | COSMETIC COMPOSITIONS COMPRISING FICUS SERUM FRACTION AND METHODS TO REDUCE THE APPEARANCE OF SKIN HYPERPIGMENTATION - The present invention provides cosmetic compositions comprising | 08-09-2012 |
20120237459 | Methods for Improving the appearance of hyperpigmented skin using a synergistic composition comprising banyan tree, lotus, and clover serum fractions - A method of improving the appearance of a hyperpigmented spot may comprise the step of applying a composition comprising an effective amount of banyan tree serum fraction, lotus serum fraction, and clover serum fraction to a hyperpigmented spot on a skin surface, wherein the composition is applied for a period of time sufficient to improve the appearance of the hyperpigmented spot. The method may include the step of identifying a hyperpigmented spot on a facial skin surface. Other methods as disclosed include a method for improving the appearance of post-inflammatory hyperpigmentation. | 09-20-2012 |
20120237460 | Methods for Improving the Appearance of Aging Skin Using a Composition Comprising Banyan Tree, Lotus, and Clover Serum Fractions - A method of improving the appearance of aging skin may comprise the step of applying a composition comprising an effective amount of banyan tree serum fraction, lotus serum fraction, and clover serum fraction to a sign of aging on a skin surface, wherein the composition is applied for a period of time sufficient to improve the appearance of the aging skin. The method may include the step of identifying a sign of aging on a facial skin surface. | 09-20-2012 |
20130022557 | Methods For Improving the Appearance of Hyperpigmented Spot(s) Using an Extract of Laminaria Saccharina - A method of improving the appearance of a hyperpigmented spot may comprise the step of applying a composition comprising a safe and effective amount of an | 01-24-2013 |
20130022558 | Methods For Imrproving the Appearance of Hyperpigmented Spot(s) and Skin Tone - A method of improving the appearance of a hyperpigmented spot and improving skin tone may comprise the steps of applying a safe and effective amount of a | 01-24-2013 |
20130022559 | Methods For Inhibiting Tyrosinase Using an Extract of Laminaria Saccharina - A method of inhibiting tyrosinase activity may involve the step of applying a composition comprising a | 01-24-2013 |
20140271506 | Cosmetic Compositions and Methods For Inhibiting Melanin Synthesis - A cosmetic composition suitable for topical application, for example, is provided. In some examples, the cosmetic composition may include undecylenoyl phenylalanine, hexyldecanol, and bisabolol. A method of reducing the synthesis of melanin by using said cosmetic compositions is also disclosed herein. | 09-18-2014 |
20140328775 | Cosmetic Compositions and Methods For Inhibiting Melanin Synthesis - A cosmetic composition suitable for topical application, for example, is provided. In some examples, the cosmetic composition may include batyl alcohol, undecylenoyl phenylalanine, hexyldecanol, and bisabolol. A method of reducing the synthesis of melanin by using the cosmetic compositions is also disclosed herein. | 11-06-2014 |