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Lemaitre

George W. Lemaitre, Charlestown, MA US

Patent application numberDescriptionPublished
20100174357Vascular Prosthesis of Varying Flexibility - A vascular prosthesis including a tubular body and a plurality of independent support members disposed on a surface of the tubular body. Spacing between the independent support members is varied to vary the flexibility of the vascular prosthesis.07-08-2010

George W. Lemaitre, Boston, MA US

Patent application numberDescriptionPublished
20120046678Over-the-Wire Valvulotomes - Over-the-wire self-sizing, self-centering valvulotomes sufficiently designed to cut valves through a wide range of vein diameters and adjust to the internal diameter of a vein as the valvulotome is being drawn through the vessel, and methods of use thereof during certain medical procedures that involve splitting valves, are disclosed herein. In an embodiment, an over-the-wire valvulotome includes a catheter having a proximal end, a distal end, and a longitudinal axis therebetween, wherein a first portion of a plurality of cutting tools engage the catheter at the distal end, and wherein an actuation mechanism engages the catheter at the proximal end; a retainer for temporarily shielding a second portion of the plurality of cutting tools, wherein the second portion includes cutting blades; and a sheath slidably moveable over the plurality of cutting blades, wherein the catheter and the retainer have internal diameters configured for passing over a guidewire.02-23-2012

Jacques Lemaitre, Lausanne CH

Patent application numberDescriptionPublished
20090068275Process for the Manufacture of Powders of Inhalable Medicaments - The invention relates to an improved process for the production of powders of an inhalable medicament by crystallization from a supersaturated fluid containing said medicament, the method comprising passing along a tubular reactor 03-12-2009

Marc Lemaitre, Alleur BE

Patent application numberDescriptionPublished
20110151451Use of Conjugates with linkers cleavable by photodissociation or fragmentation for mass spectromety analysis of tissue sections - The invention concerns a method for determining at least one target molecule map in a tissue section, using at east one (A-X)n-B conjugate, wherein A is a tag molecule of known molecular weight, X is a linker that is cleaved during sample desorption/ionization, n is an integer of at least 1, and B is a binding molecule that binds specifically to said target molecule. When using MALDI mass spectrometry, said linker molecule X may be cleaved by photodissociation during sample laser irradiation if photocleavable at the wavelength of said MALDI laser. Alternatively, when using UV-MALDI, IR-MALDI, SIMS or DESI mass spectrometry, said linker molecule X may be cleaved by fragmentation during sample desorption/ionization.06-23-2011

Sergio Lemaitre, Whitefish Bay, WI US

Patent application numberDescriptionPublished
20090260233METHOD OF PRODUCING A HIGH VOLTAGE STABLE CATHODE FOR AN X-RAY TUBE - A method of producing a cathode for use in an x-ray tube assembly is provided including machining an emission aperture into a cup emission surface portion of a cup structure. The cup structure is comprised of a cup base portion opposite the cup emissions surface portion. Electro-discharge machining is used to form an electro-discharge machining slot into the cup structure to provide access to the interior of the cup structure. Electro-discharge machining is used to form a transverse coil chamber within the interior by way of the electro-discharge machining slot such that the transverse coil chamber is formed between the cup base portion and the cup emissions surface portion while retaining an essentially contiguous emissions surface perimeter surrounding the emission aperture.10-22-2009
20110026681METHOD OF FAST CURRENT MODULATION IN AN X-RAY TUBE AND APPARATUS FOR IMPLEMENTING SAME - An x-ray imaging system includes a detector positioned to receive x-rays, and an x-ray tube coupled to a mount structure. The x-ray tube is configured to generate x-rays toward the detector and includes a target, a cathode cup, an emitter attached to the cathode cup and configured to emit a beam of electrons toward the target, the emitter having a length and a width, and a one-dimensional grid positioned between the emitter and the target and attached to the cathode cup at one or more attachment points. The one-dimensional grid includes a plurality of rungs that each extend in a direction of the width of the emitter, and the plurality of rungs are configured to expand and contract relative to the one or more attachment points without substantial distortion with respect to the emitter.02-03-2011
20110116593SYSTEM AND METHOD FOR BEAM FOCUSING AND CONTROL IN AN INDIRECTLY HEATED CATHODE - An indirectly heated cathode assembly is presented. The indirectly heated cathode assembly includes at least one electron source for generating a first electron beam, an emitter for producing a second electron beam when heated by the first electron beam and a focusing electrode for controlling, and directing the first electron beam towards the emitter.05-19-2011
20110142193X-RAY TUBE FOR MICROSECOND X-RAY INTENSITY SWITCHING - An injector for an X-ray tube is presented. The injector includes an emitter to emit an electron beam, at least one focusing electrode disposed around the emitter, wherein the at least one focusing electrode focuses the electron beam and at least one extraction electrode maintained at a positive bias voltage with respect to the emitter, wherein the at least one extraction electrode controls an intensity of the electron beam.06-16-2011
20110142204APPARATUS FOR MODIFYING ELECTRON BEAM ASPECT RATIO FOR X-RAY GENERATION - An apparatus for modifying an aspect ratio of an electron beam to form a focal spot having a desired size and aspect ratio on a target anode is disclosed. The apparatus includes an emitter element configured to generate an electron beam having a first aspect ratio shape and an extraction electrode positioned adjacent to the emitter element to extract the electron beam out therefrom, the extraction electrode including an opening therethrough. The apparatus also includes at least one shaping electrode positioned to receive the electron beam after passing through the extraction electrode, the shaping electrode defining a non-circular aperture therein and being configured to provide at least one of shaping and focusing of the electron beam to have a second aspect ratio shape different from the first aspect ratio shape so as to form a focal spot having a desired size and aspect ratio on a target anode.06-16-2011
20110150187APPARATUS AND METHOD FOR CALIBRATING AN X-RAY TUBE - An apparatus and method for calibrating an x-ray tube include a computer programmed to acquire a starter voltage/current value corresponding to a width, a length, or a position of a target focal spot capable of being generated by the x-ray tube. The computer is programmed to generate an electron beam and to steer the electron beam based on the starter voltage/current value. The computer is also programmed to steer the electron beam based on a value adjusted from the starter voltage/current value. The computer is programmed to calculate a final voltage/current value that is configured to generate the width, length, or position of the target focal spot based on the starter voltage/current value and the adjusted starter voltage/current value.06-23-2011
20110188637X-RAY CATHODE AND METHOD OF MANUFACTURE THEREOF - The disclosed embodiments include embodiments such as an X-ray tube cathode filament system. The X-ray tube cathode filament system includes a substrate and a coating disposed on the substrate. In this cathode filament system, an electron beam is emitted from the coating but not from the substrate. The electron beam is produced through the use of the thermionic effect.08-04-2011
20110241575PIERCE GUN AND METHOD OF CONTROLLING THEREOF - A system and method for controlling the temperature of both an electron emitter and a filament to their lowest possible operating temperature is disclosed. The apparatus includes a filament, an electron emitter heated by the filament to generate an electron beam, and a power supply configured to supply power to each of the filament and the electron emitter. The apparatus also includes a control system to control a supply of power to each of the filament and the electron emitter, with the control system being configured to receive an input indicative of a desired electron emitter operating temperature, cause a desired voltage to be applied between the electron emitter and the filament, and cause a desired voltage to be applied to the filament based on the desired emitter element operating temperature, so as to minimize an operating temperature of the electron emitter and the filament.10-06-2011
20110255667LOW BIAS mA MODULATION FOR X-RAY TUBES - A segmented thermionic emitter is provided. The segmented thermionic emitter has, among other features, a plurality of segments substantially spanning an entire length of the thermionic emitter and aligned substantially parallel with one another. In one embodiment, the segmented thermionic emitter may allow milli-amp modulation of an X-ray tube at voltages less than approximately 2 kV.10-20-2011
20110280363METHOD OF FAST CURRENT MODULATION IN AN X-RAY TUBE AND APPARATUS FOR IMPLEMENTING SAME - An X-ray tube includes a target and a cathode assembly. The cathode assembly includes a first filament configured to emit a first beam of electrons toward the target, a first gridding electrode coupled to the first filament, a second filament configured to emit a second beam of electrons toward the target, and a second gridding electrode coupled to the second filament.11-17-2011

Patent applications by Sergio Lemaitre, Whitefish Bay, WI US