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Lee, NC

Ade Lee, Cary, NC US

Patent application numberDescriptionPublished
20110078198AUTOMATIC SERIAL NUMBER AND REQUEST ID ALLOCATION IN A REPLICATED (CLONED) CERTIFICATE AUTHORITY AND DATA RECOVERY MANAGEMENT TOPOLOGY - A Serial Number Management System (SNMS) automatically manages the allocation of unique serial numbers to certificate authority servers in a replicated server environment. The SNMS automatically detects that a Certificate Authority (CA) server has a need for a new set of unused serial numbers. The SNMS obtains a global serial number that is available to be used by any of the CA servers in a replication domain. The SNMS determines the new set of the unused serial numbers using the global serial number and updates the global serial number.03-31-2011
20110078304Automatic Server Administration of Serial Numbers in a Replicated Certificate Authority Topology - A Serial Number Management System (SNMS) automatically manages the allocation of unique serial numbers to certificate authority servers in a replicated server environment. The SNMS automatically detects that a Certificate Authority (CA) server has a need for additional unused serial numbers. The SNMS identifies a provider CA server that has unused serial numbers. The SNMS obtains a portion of the unused serial numbers from the provider CA server.03-31-2011
20110078772LDAP SECURITY DOMAIN DATA STORAGE - A Security Domain Access System (SDAS) provides highly available security domain data. The SDAS receives a request pertaining to a security domain. The request includes credentials for accessing a security domain manager server. The SDAS selects one of a plurality of security domain manager servers to process the request based on the credentials and the availability of each of the plurality of security domain manager servers. The SDAS forwards the request to the selected security domain manager server.03-31-2011
20110113239RENEWAL OF EXPIRED CERTIFICATES - A method and system for renewal of expired certificates is described. In one embodiment, a method, implemented by a computing system programmed to perform operations, includes receiving, at a certificate manager of a computing system from a requester, a certificate renewal request for an original digital certificate that has already expired, and renewing the expired certificate as a renewed certificate by the certificate manager when the certificate renewal request is approved. The renewed certificate comprises the same key pair as the original certificate, but includes a new expiration date, and wherein the renewed certificate is functionally identical to the original certificate.05-12-2011
20110113240CERTIFICATE RENEWAL USING ENROLLMENT PROFILE FRAMEWORK - A method and system for renewing digital certificates using an enrollment profile framework is described.05-12-2011
20110167256ROLE-BASED ACCESS CONTROL UTILIZING TOKEN PROFILES - A method and system for managing role-based access control of token data using token profiles is described.07-07-2011
20110167483ROLE-BASED ACCESS CONTROL UTILIZING TOKEN PROFILES HAVING PREDEFINED ROLES - A method and system for managing role-based access control of token data using token profiles having predefined roles is described.07-07-2011
20110293098KEY RECOVERY MECHANISM - A method and system for key recovery for a private key of a digital certificate for a client.12-01-2011
20110296171KEY RECOVERY MECHANISM - A method and system for server-side key generation for non-token clients is described.12-01-2011

Alvin Lee, Charlotte, NC US

Patent application numberDescriptionPublished
20110055072EVENT PROCESSING FOR DETECTION OF SUSPICIOUS FINANCIAL ACTIVITY - Event processing for detection of suspicious financial activity is disclosed. Financial events can be detected by receiving data from a plurality of detection channels. Events are consolidated or otherwise grouped based on common relationship factors, such as related accounts, related parties or the like. Factual data associated with the events, referred to herein as risk attributes, is collected and risk factors are assessed based on one or more of the risk attributes. The risk factors are subsequently used to determine whether an event group should be elevated to the case level for further investigation.03-03-2011

Charles Y. Lee, Charlotte, NC US

Patent application numberDescriptionPublished
20110236875Composition and Method for the Restoration and Preservation of Transplant Organs Procured From DCD Donors - The present invention provides a perfusion solution comprising specific metabolic agents, antioxidant agents, and membrane stabilizer agents that can help improve preservation, organ viability, and in some cases recover organs that would otherwise being unusable for transplantation. In a further embodiment, the perfusion solution can be used in combination with hypothermic machine perfusion. It has been found that combination of the perfusion solution and hypothermic machine perfusion can help prevent or reduce further damage to the organ and restore the organ's anti-oxidant system, stabilize the cellular cytoskeleton and cellular membranes, inhibit arachidonic acid pathway, provide oncotic support, reduce interstitial edema formation, and help restore energy stores within the organ. As a result, the method can be used to improve the viability of otherwise marginal donor organs.09-29-2011

Clarence Lee, Charlotte, NC US

Patent application numberDescriptionPublished
20100208976METHOD AND SYSTEM FOR ENHANCED CHECK IMAGE PRIVACY - A method and system for enhanced check image privacy are disclosed. Embodiments of the present invention provide a way to automatically link the results from quality assurance software to a check image archive to appropriately mark images as unretrievable by customers. Images are interrogated with a data matching algorithm to determine whether a confidence score expressing a likelihood that the image matches associated, stored magnetic ink character recognition (MICR) data is below a pre-set threshold. The image can be then automatically designated in the financial document archive. The image can be displayed to an operator for analysis when the confidence score is above the pre-set threshold and below a pre-set limit, or in cases where the confidence score cannot be determined by the data matching algorithm. 08-19-2010

Daekee Lee, Chapel Hill, NC US

Patent application numberDescriptionPublished
20100015124Modulation of epidermal growth factor heterodimer activity - Provided is a method for screening a plurality of compounds for an ability to bind to a heterodimer of EGFR and another ERBB family member. Also provided are compounds that bind to heterodimers of EGFR and another ERBB family member; and methods of using the identified compounds to suppress the growth of a tumor associated with EGFR heterodimer activity in a subject.01-21-2010

Dale Joel Lee, Fuquary Varina, NC US

Patent application numberDescriptionPublished
20090150300AUTOMATED FORECLOSURE AND ASSET DISPOSITION METHODS, SYSTEMS, AND COMPUTER PROGRAM PRODUCTS - Automated foreclosure and asset disposition methods, systems, and computer program products are provided, such as for automating a property foreclosure matter. According to one aspect, the subject matter described can include providing a data inquiry for receiving user input relating to a foreclosure matter. In response to the data inquiry, information can be retrieved over a data network relating to the foreclosure matter and documents can be generated relating to the foreclosure matter either automatically or in response to a document request. Information can be presented such as, for example, tracking information relating to the foreclosure matter.06-11-2009

Darryl Victor Lee, Greenville, NC US

Patent application numberDescriptionPublished
20090206113Combination coat and head hanger and method of manufacturing same - A combination coat and hat hanger comprises of a jumbo plastic coat hanger. What is new in the art of the combination coat and hat hanger is a jumbo hat peg approximately six inches long with a plastic ball on one end mounted in the center of the lower portion and protruding at a 45 degree angle. The hat peg allows for a hat and a coat to be hung on the hanger simultaneously.08-20-2009

David T. Lee, Charlotte, NC US

Patent application numberDescriptionPublished
20100030686RETIREMENT PAYCHECK APPARATUS AND METHODS - Apparatus and methods for providing funds to a bank customer. A bank customer may have a retail bank account in the custody of a bank. The bank may provide retail banking services to the bank customer in connection with the retail bank account. After providing the retail banking service, the bank may electronically link a retirement fund management module to the bank account. The retirement fund management module may be configured to transfer a predetermined amount of retirement funds into the bank account. The transfer may be made in accordance with rules. The rules may be selected by the bank customer.02-04-2010

Donjuma S. Lee, Raleigh, NC US

Patent application numberDescriptionPublished
20090070757METHODS, SYSTEMS AND COMPUTER PRODUCTS FOR A DYNAMIC REPOSITORY - A software development service offering of generating and installing software applications packages on computer systems running a set of operating systems including LINUX and UNIX operating systems, by creating a dynamic repository; populating a plurality software packages; running a tool that creates a set of index files, wherein the set of index files includes a menu of the plurality of software packages, wherein each software package in the plurality of software packages contains a set of contents; determining whether a software package is included in a menu of the plurality of software packages; and delivering to a client system the software package requested in a selection request, or delivering to the client system an other software package, when the software package is not included in the menu of the plurality of software packages.03-12-2009

Douglas C. Lee, Apex, NC US

Patent application numberDescriptionPublished
20100196875HUMAN ERYTHROVIRUS - Nucleic acid molecules derived from sequences of novel human parvovirus B19 variant genomes are provided. Also provided are assays and kits comprising the nucleic acid molecules.08-05-2010

Eric Chi Shun Lee, Charlotte, NC US

Patent application numberDescriptionPublished
20100170047ARTICLE AND METHOD FOR DISTRESS-WASHING FABRIC - An article for distress-washing fabric comprising a hollow float and at least one distressing feature projecting outwardly from an outer surface of the float, wherein the article is substantially wear resistant and does not produce residue as a result of impact with fabric, internal surfaces of a washing machine and additional articles for distress-washing fabric. A method for distress-washing fabric utilizing an article described herein.07-08-2010

Harold Lee, Holly Springs, NC US

Patent application numberDescriptionPublished
20090019018DATABASE QUERY TABLE SUBSTITUTION - The subject mater herein relates to requesting data from a database and, more particularly, to database query table substitution. Various embodiments provide systems, methods, and software to evaluate requests for data from a database and make table substitutions in the request to reduce a number of tables queried. Some embodiments include receiving a data request including data from two or more database table columns and building a list of all database tables specified in the data request. Some such embodiments further include, for each column in the data request, identifying each table from the list of all tables within which the column is present and identifying a least number of one or more tables that together include all of the columns of the data request. The data request may then be modified by changing the table of one or more of the columns in the received data requests.01-15-2009
20110161135METHOD AND SYSTEMS FOR COLLATERAL PROCESSING - Methods and systems for processing collaterals are described. A method may include receiving qualifying criteria from a client. The qualifying criteria may define assignments of one or more collaterals. An assignment tool may be generated based on the qualifying criteria. The assignment tool may include a number of stored attributes and one or more interaction attribute to be determined based on a customer interaction. The assignment tool may be used to assign a collateral to a customer. Additional methods and systems are disclosed.06-30-2011

Patent applications by Harold Lee, Holly Springs, NC US

Hyoung Ik Lee, Cary, NC US

Patent application numberDescriptionPublished
20080312272ARYLOAZOL-2-YL CYANOETHYLAMINO COMPOUNDS, METHOD OF MAKING AND METHOD OF USING THEREOF - The present invention relates to novel aryloazol-2-yl-cyanoethylamino derivatives of formula (I):12-18-2008
20100125089ENANTIOMERICALLY ENRICHED ARYLOAZOL-2-YL CYANOETHYLAMINO COMPOUNDS, METHOD OF MAKING AND METHOD OF USING THEREOF - The present invention relates to novel aryloazol-2-yl-cyanoethylamino derivatives substantially enriched in an enantiomer of formula (I):05-20-2010
20100130565THIOAMIDE COMPOUNDS, METHOD OF MAKING AND METHOD OF USING THEREOF - The present invention relates to novel thioamide derivatives of formula (I) and formula (Ia):05-27-2010
201002491941-ARYL-5-ALKYL PYRAZOLE DERIVATIVE COMPOUNDS, PROCESSES OF MAKING AND METHODS OF USING THEREOF - Provided are 1-aryl-5-alkyl pyrazole compounds, of formula (I):09-30-2010
20110152312ANTIPARISITIC DIHYDROAZOLE COMPOUNDS AND COMPOSITIONS COMPRISING SAME - The present invention relates to novel dihydroazole of formula (I) and salts thereof:06-23-2011
20110190231THIOAMIDE COMPOUNDS, METHOD OF MAKING AND METHOD OF USING THEREOF - The present invention relates to novel thioamide derivatives of formula (I) and formula (Ia):08-04-2011

Patent applications by Hyoung Ik Lee, Cary, NC US

Jeffrey Lee, Durham, NC US

Patent application numberDescriptionPublished
20110114081SOLAR COLLECTOR SYSTEM - A solar energy collecting system comprises a manifold defining a closed fluid passage between a condensation point and a heating point. The manifold includes a plurality of heat exchange members configured to be in heat exchange relationship with the fluid passage at the heating point, and a heat sink at the condensation point. A plurality of solar energy collector members extend from and operably connect to the heat exchange members of the manifold. The solar energy collector members collect solar energy and transform it into heat energy. Heat energy is transferred from the solar energy collector members to the heat exchange members and to a fluid in the passage in the manifold at the heating point so as to heat the fluid into a vapor. The fluid is circulated in heat exchange relationship to the condensation point where heat energy is transferred to the heat sink so as to cool the fluid to a liquid. The fluid repeatedly cycles between a vaporized state at the heat exchange members and a liquefied state at the condensation point.05-19-2011

Jeffrey Lynn Lee, Moyock, NC US

Patent application numberDescriptionPublished
20090107329JET HOPPER - Apparatus for use in injecting powder materials into the flue gasses flowing through a baghouse compartment in conjunction with the performance of selected operating processes on the compartment fabric filters first entrains the powdered material into a pressurized fluid column to create a gaseous powder material plume that is injected into the flue gasses, thereby providing a more uniform entrainment of the powder materials into the flue gasses.04-30-2009

Joo Y. Lee, Durham, NC US

Patent application numberDescriptionPublished
20120005195CREATING AN ONTOLOGY USING AN ONLINE ENCYCLOPEDIA AND TAG CLOUD - A method for generating an ontology may include selecting, by a processing device, a tag in a tag cloud. The method may also include searching, by the processing device, an online encyclopedia for content corresponding to the selected tag and determining, by the processing device, at least one category to which the content belongs in the online encyclopedia in response to finding the content corresponding to the selected tag in the online encyclopedia. The method may additionally include adding, by the processing device, a class to the ontology corresponding to the at least one category of the content in the online encyclopedia.01-05-2012

Joseph J. Lee, Holly Springs, NC US

Patent application numberDescriptionPublished
20090006401FILE MONITORING METHOD, SYSTEM, AND PROGRAM PRODUCT - The present invention provides a file monitoring approach that runs on bridge servers in an SNI environment, monitors a defined folder and detects the same file existing (by its file name persisting) for a predetermined interval period or longer. Optionally, the program can attempt to unlock the ticket corresponding to the inbound update. It also sends notification of the condition to bridge support. If the option to unlock the ticket is used, it reports on the success or failure of the attempt to unlock the ticket in the notification sent. One advantage of using this approach is to automatically detect when this condition is occurring to avoid bridge log space problems, possible customer calls to a helpdesk to request tickets be unlocked, and to notify bridge support. This approach helps to automate bridge support.01-01-2009

Joseph Kinman Lee, Raleigh, NC US

Patent application numberDescriptionPublished
20080309493WIRELESS SYSTEM TO DETECT PRESENCE OF CHILD IN A BABY CAR SEAT - A wireless system that detects the presence of a child in a safety seat located in the passenger cabin of a vehicle includes a controller responsive to signals generated by sensors monitoring predefined functions of the vehicle, RFID tag device attached to the safety seat and RFID tag reader mounted in the cabin. The system generates control signals which activate an alarm, open the doors of the vehicle and roll down windows if the child is left in the safety seat of an unattended vehicle.12-18-2008

Patent applications by Joseph Kinman Lee, Raleigh, NC US

Ju Y. Lee, Durham, NC US

Patent application numberDescriptionPublished
20090327189DYNAMIC ONTOLOGY-DRIVEN TEMPLATE SELECTION - One aspect of the present invention includes dynamically selecting templates through the use of an ontology. In one embodiment, an ontology is defined to structure information system content, and an ontology classification is then assigned when content is provided to the information system. Based on this classification, the most appropriate template classified in the ontology is applied to the content. If a template exists at the content item's ontology level, this template is applied to the content. If no template exists, then the ontology tree is navigated upward to locate a template at the nearest ancestor ontology level. If a template was found by navigating the ontology tree, then this template is applied to the content item.12-31-2009
20090327337DYNAMIC ONTOLOGY-DRIVEN TEMPLATE SELECTION - One aspect of the present invention includes dynamically selecting templates through the use of an ontology. In one embodiment, an ontology is defined to structure information system content, and an ontology classification is then assigned when content is provided to the information system. Based on this classification, the most appropriate template classified in the ontology is applied to the content. If a template exists at the content item's ontology level, this template is applied to the content. If no template exists, then the ontology tree is navigated upward to locate a template at the nearest ancestor ontology level. If a template was found by navigating the ontology tree, then this template is applied to the content item.12-31-2009
20100114886RELEVANCE CONTENT SEARCHING FOR KNOWLEDGE BASES - Embodiments of the present invention provide a novel and non-obvious method, server and computer program product for finding relevant content in a knowledge base. A method for finding items that are related to a user selected item in a knowledge base is provided. The method can include generating a first list of knowledge base items with a defined relationship to the user selected item and generating a second list of knowledge base items that belong to the same category as a category of the user selected item. The method can further include generating a third list of knowledge base items having one or more tags identical to one or more tags of the user selected item and selecting a first set of knowledge base items that are present in the first, second or third lists. The method can further include displaying the first set of knowledge base items as most relevant.05-06-2010

Kim Kelly Lee, Gastonia, NC US

Patent application numberDescriptionPublished
20100307659Filter Media and System and Method of Manufacturing the Same - Filter media and a method for manufacturing filter media is disclosed. The filter media includes a corrugated porous filter media layer including a top surface and a bottom surface, wherein the corrugated porous filter media layer includes one or more peaks separated by valleys, a second porous filter media layer including a top surface and a bottom surface, the valleys of the corrugated porous filter media proximate the second porous filter media layer, and an ultrasnoically weldable material disposed between one or more of the valleys of the corrugated porous filter media layer and the top surface of the second porous filter media layer.12-09-2010

Kou-Hsiung Lee, Chapel Hill, NC US

Patent application numberDescriptionPublished
20100292324Multi-Substituted Diarylanilines as Non-Nucleoside HIV Reverse Transcriptase Inhibitors, and Preparation and Use Thereof - The present invention relates to multi-substituted m-diarylanilines or pharmaceutically acceptable salts thereof, wherein X, R11-18-2010

Kuo-Hsiung Lee, Chapel Hill, NC US

Patent application numberDescriptionPublished
20080300254Tylophorine Analogs as Antitumor Agents - Compounds of Formula I are described: preferably subject to the proviso that either (a) R12-04-2008
20090118356NEO-TANSHINLACTONE AND ANALOGS AS POTENT AND SELECTIVE ANTI-BREAST CANCER AGENTS - Compounds of Formulas I-II are described,05-07-2009
20100168064NOVEL HYDROPHILIC DERIVATIVES OF 2-ARYL-4-QUINOLONES AS ANTICANCER AGENTS - 2-aryl-4-quinolones are converted into phosphates by reacting with tetrabenzyl pyrophosphate to form dibenzyl phosphates thereof, which are then subject to hydrogenation to replace dibenzyl groups with H, followed by reacting with Amberlite IR-120 (Na+ form) to form disodium salts. The results of preliminary screening revealed that these phosphates showed significant anti-cancer activity. A novel intermediate, 2-selenophene 4-quinolone and Λ/, Λ/-dialkylaminoalkyl derivatives of 2-phenyl-4-quinolones are also synthesized. These novel intermediates exhibited significant anticancer activities.07-01-2010
20100197784NOVEL CURCUMIN ANALOGUES AND USES THEREOF - The present invention relates to compounds capable of acting as androgen receptor antagonists, pharmaceutical formulations containing the same, and methods of use thereof. Such uses include, but are not limited to, use as antitumor agents, particularly for the treatment of cancers such as colon, skin and prostate cancer and to induce androgen receptor antagonist activity in a subject afflicted with an androgen-related affliction. Examples of androgen-related afflictions include, but are not limited to, baldness, hirsutism, behavioral disorders, acne, and uninhibited spermatogenesis wherein inhibition of spermatogenesis is so desired.08-05-2010
20110152229BETULINIC ACID DERIVATIVES AS ANTI-HIV AGENTS - The present invention provides compounds of the general structure:06-23-2011
20110224205USE OF CURCUMIN OR ITS ANALOGUES IN CANCER THERAPY UTILIZING EPIDERMAL GROWTH FACTOR RECEPTOR TYROSINE KINASE INHIBITOR - Provided is combined use of an epidermal growth factor receptor tyrosine kinase inhibitor (EGFR-TKI) and curcumin or its analogue in cancer therapy, which reduces side effects resulting from the EGFR-TKI and reduces doses of the EGFR-TKI needed for the therapy, particular in a patient resistant to the treatment with the EGFR-TKI alone.09-15-2011
20110275707SUBSTITUTED AFPO (6-ARYL-4H-FURO[3,2-C]PYRAN-4-ONE) DERIVATIVES AS ANTI-CANCER AGENTS - Compounds of Formulas I are described, along with methods of using such compounds for the treatment of cancer and pharmaceutical formulations thereof.11-10-2011

Patent applications by Kuo-Hsiung Lee, Chapel Hill, NC US

Margaret Lee, Clayton, NC US

Patent application numberDescriptionPublished
20110272342Food Straining Device - Disclosed is a system for a food straining device. In various embodiments a food product is placed within a bowl having drainage holes or a mesh bag. A lid component is coupled with or adapted to work in conjunction with the bowl or bag such that the lid causes the food product to be compressed such that excess liquid can escape through the drainage holes or through the mesh. An optional catch bowl can be used to capture and retain the drained liquid.11-10-2011

Mikyong Lee, Durham, NC US

Patent application numberDescriptionPublished
20100009851PLANT REGULATORY SEQUENCES - The present invention relates to regulatory sequences. In particular, the invention relates to a regulatory nucleotide sequence, at least part of which has a transcription initiation function directing expression of an operably associated protein encoding polynucleotide of interest to non-pollen tissue, but not or substantially not to pollen.01-14-2010

Moses T. Lee, Fayetteville, NC US

Patent application numberDescriptionPublished
20110155303IONOMERIC SHEETING IN ROLL FORM AND PROCESS FOR PRODUCING SAME - Provided herein is relatively thick ionomeric sheeting that can be taken up into a roll and supplied in continuous form. Also provided herein are methods of manufacturing rolls of relatively thick, continuous ionomeric sheeting. Further provided herein are methods of producing glass laminates, wherein the relatively thick ionomeric sheeting is not conditioned to reduce curvature prior to stacking the pre-press assembly. These continuous rolls eliminate costly cutting and stacking steps in ionomeric sheeting that is intended for use as interlayers in laminated structures, for example safety glass and photovoltaic cells.06-30-2011

Pucci Lee, Holly Springs, NC US

Patent application numberDescriptionPublished
20090327973PRESERVING A COMPLETE HISTORY OF A SET OF APPLICATION ACTIONS WHEN NON-LINEAR INTERACTIONS ARE PERMITTED - An action history maintains a set of ordered application actions associated with a user. A user interface of a software application can include a back control and a forward control, which utilize the action history. Specifically, the back control revokes a most recent action and the forward control reapplies a previously revoked action. Thus, the forward and backward controls change which page is rendered in the software application. Unlike traditional implementations, the invention maintains a complete set of actions within the action history in a non-linear context. That is, when a new action is inserted into a history from a non-terminal state (i.e., actions able to be reapplied are available upon a selection of the forward control) then the new action is inserted immediately after the current action. The historic actions are maintained in order after the new action in the action history.12-31-2009

Randy Lee, Wake Forest, NC US

Patent application numberDescriptionPublished
20100125898USE OF AUTHENTICATION INFORMATION TO MAKE ROUTING DECISIONS - Methods and systems for utilizing authentication attributes to determine how to direct traffic flows are provided. According to one embodiment, a program storage device readable by a network device associated with a service provider is provided. The program storage device tangibly embodies a program of instructions executable by a processor of the network device to perform method steps for authenticating users and establishing appropriate service sessions. An end user from whom a connection request is received is caused to be prompted for login credentials. The received login credentials are then caused to be authenticated by an authentication server. Responsive to successful authentication, a service session is established for the end user and customer separation is maintained among the multiple customers by creating a routing entry, according to which subsequent packets associated with the service session are routed, based on authentication attributes returned by the authentication server.05-20-2010

Sang Don Lee, Chapel Hill, NC US

Patent application numberDescriptionPublished
20100300221Aerosol particle deposition on surfaces - A method and apparatus for generating a standardized surface contaminated by an aerosol deposited on its surface is described. Aerosols are propelled horizontally onto a vertical surface. The standardized contaminated surface is used to evaluate the effectiveness of cleaning and removing techniques.12-02-2010

Sang Jin Lee, Winston-Salem, NC US

Patent application numberDescriptionPublished
20100331980ALIGNED SCAFFOLDING SYSTEM FOR SKELETAL MUSCLE REGENERATION - Provided herein are anisotropic muscle implants that have a biodegradable scaffold comprising a plurality of fibers oriented along a longitudinal axis. The implants may include mammalian muscle cells seeded and/or fused into myotubes on the scaffold. Methods of forming the muscle implants are provided, as are methods of treating a subject in need of skeletal muscle reconstruction.12-30-2010
20110097379DIRECTED STEM CELL RECRUITMENT - The invention is directed to methods of inducing cell recruitment and tissue regeneration at a target site in a subject. It is also based, in part, on the discovery that a subject's own biologic resources and environmental conditions can be used for in situ tissue regeneration and thereby reduce or eliminate the need for donor cell procurement and ex vivo manipulation of such donor cells. Methods are disclosed for recruitment of a subject's own stem cells to a target region by inducing a sustained positive pressure at a target site, such as the kidney, thereby increasing the number of pluripotent cells capable of differentiating to regenerate the target tissue.04-28-2011
20110172683TISSUE EXPANDER - Provided herein is a tissue stretching device including a tissue clamping member defining an area in a Z plane, wherein the tissue clamping member is configured to hold tissue parallel to the Z plane. Methods of use of the tissue stretching device to stretch a tissue as well as for culturing organized tissues are also provided. Stretched and/or cultured tissues produced by these processes are also provided, as well as methods of treatment making use of the same.07-14-2011

Patent applications by Sang Jin Lee, Winston-Salem, NC US

Sa Yong Lee, Raleigh, NC US

Patent application numberDescriptionPublished
20090178591Carbohydrate-gypsum composite - A carbohydrate-gypsum composite for use as a bonding agent in manufacturing gypsum construction materials is disclosed. The composite includes a carbohydrate substituted with sulfate moieties such as cellulose sulfate and a crystalline calcium sulfate dihydrate. The composite may be used in bonding paper cover sheets to a gypsum core to form a gypsum wallboard. Also disclosed are methods of making the composite and methods of making gypsum wallboard with the composite.07-16-2009

Seok-Won Lee, Charlotte, NC US

Seungbae Lee, Greensboro, NC US

Patent application numberDescriptionPublished
20110148252MEMS VIBRATING STRUCTURE USING A SINGLE-CRYSTAL PIEZOELECTRIC THIN-FILM LAYER HAVING DOMAIN INVERSIONS - The present invention relates to a micro-electro-mechanical systems (MEMS) vibrating structure supported by a MEMS anchor system, and includes a single-crystal piezoelectric thin-film layer having domain inversions, which determine certain vibrational characteristics of the MEMS vibrating structure. The MEMS vibrating structure may have dominant lateral vibrations or dominant thickness vibrations. The single-crystal piezoelectric thin-film layer may include Lithium Tantalate or Lithium Niobate, and may provide MEMS vibrating structures with precise sizes and shapes, which may provide high accuracy and enable fabrication of multiple resonators having different resonant frequencies on a single substrate.06-23-2011

Shuliang Lee, Durham, NC US

Patent application numberDescriptionPublished
20120004240INHIBITORS OF AKT ACTIVITY - The instant invention provides for substituted fused naphthyridine derivatives that inhibit Akt activity. In particular, the compounds disclosed selectively inhibit one or two of the Akt isoforms. The invention also provides for compositions comprising such inhibitory compounds and methods of inhibiting Akt activity by administering the compound to a patient in need of treatment of cancer.01-05-2012

Stephen Aaron Lee, Durham, NC US

Patent application numberDescriptionPublished
20090126043GENERATION OF PLANTS WITH IMPROVED PATHOGEN RESISTANCE AND DROUGHT TOLERANCE - The present invention is directed to plants that display a pathogen resistance and increased drought tolerance phenotype due to altered expression of a PRDT1 nucleic acid. The invention is further directed to methods of generating plants with a pathogen resistance and increased drought tolerance phenotype.05-14-2009
20100275321GENERATION OF PLANTS WITH IMPROVED PATHOGEN RESISTANCE AND DROUGHT TOLERANCE - The present invention is directed to plants that display a pathogen resistance and increased drought tolerance phenotype due to altered expression of a PRDT1 nucleic acid. The invention is further directed to methods of generating plants with a pathogen resistance and increased drought tolerance phenotype.10-28-2010

Patent applications by Stephen Aaron Lee, Durham, NC US

Taiyeong Lee, Cary, NC US

Patent application numberDescriptionPublished
20100153456Computer-Implemented Systems And Methods For Variable Clustering In Large Data Sets - Computer-implemented systems and methods are provided for creating a cluster structure from a data set containing input variables. Global clusters are created within a first stage, by computing a similarity matrix from the data set. A global cluster structure and sub-cluster structure are created within a second stage, where the global cluster structure and the sub-cluster structure are created using a latent variable clustering technique and the cluster structure output is generated by combining the created global cluster structure and the created sub-cluster structure.06-17-2010
20110161263Computer-Implemented Systems And Methods For Constructing A Reduced Input Space Utilizing The Rejected Variable Space - Computer-implemented systems and methods are provided for generating a data model. A variable predictiveness determination is performed on the population of candidate variables. A plurality of variables from the population of candidate variables are selected as a selected set based on the variable predictiveness values. A plurality derived variables are generated based on variables in the rejected set without consideration of any variables in the selected set. One or more derived variables are selected as based on derived variable predictiveness values of the derived variables, and the selected set and the one or more selected derived variables are stored as the model input variables for the data model.06-30-2011

William B. Lee, Charlotte, NC US

Patent application numberDescriptionPublished
20090264225GOLF TEE - A golf tee made of an elastomeric material includes a base section for positioning on a ground surface, and a concave head section for supporting a golf ball thereon. The tee can be made of a polymeric foam, such as polyurethane foam orethylene vinyl acetate foam. The tee can have a generally frusto-conical shape, with the base section having a larger diameter than the head section. A notch can be formed in the tee for exposing the ball to a golf club head. The tee can include a pointing member extending outwardly from, such that the pointing member points in a direction of a golf green and provides a visual cue to a user of the tee as to the direction of the golf green while swing at the ball.10-22-2009

Yi-Shan Lee, Chapel Hill, NC US

Patent application numberDescriptionPublished
20100292169METHODS AND COMPOSITIONS FOR REGULATING HDAC6 ACTIVITY - The present invention provides methods and compositions for inhibiting Hsp90 activity in a cell, comprising contacting the cell with an inhibitor of histone deacetylase 6 (HDAC6)11-18-2010

Yueh Lee, Durham, NC US

Patent application numberDescriptionPublished
20100239064Methods, systems, and computer program products for multiplexing computed tomography - Methods, systems, and computer program products for multiplexing computed tomography are disclosed. According to one aspect, the subject matter described herein can include illuminating an object with a plurality of x-ray beams from a plurality of viewing angles, wherein each x-ray beam has a distinct waveform; detecting the x-ray intensities of the plurality of pulsed x-ray beams as a function of time, and extracting individual projection image data from the detected x-ray intensities based on the distinct waveforms of the x-ray beams for combining the projection image data to generate three-dimensional tomographic image data of the object.09-23-2010

Patent applications by Yueh Lee, Durham, NC US

Yueh-Ling Lee, Raleigh, NC US

Patent application numberDescriptionPublished
20090017309COMPOSITIONS AND METHODS FOR CREATING ELECTRONIC CIRCUITRY - The present invention is directed to non-lithographic patterning by laser (or similar-type energy beam) ablation, where the ablation system ultimately results in circuitry features that are relative free from debris induced over-plating defects (debris relating to the ablation process) and fully additive plating induced over-plating defects. Compositions of the invention include a circuit board precursor having an insulating substrate and a cover layer. The insulating substrate is made from a dielectric material and also a metal oxide activatable filler. The cover layer can be sacrificial or non-sacrificial and is used to remediate unwanted debris arising from the ablation process.01-15-2009
20090263639LIGHT ACTIVATABLE POLYIMIDE COMPOSITIONS FOR RECEIVING SELECTIVE METALIZATION, AND METHODS AND COMPOSITIONS RELATED THERETO - The present invention relates generally to polyimide composites having dispersed in the polyimide base matrix, useful spinel crystal fillers wherein the composite has a visible-to-infrared light extinction coefficient between and including 0.05 and 0.60 microns10-22-2009
20100009173COMPOSITIONS AND METHODS FOR CREATING ELECTRONIC CIRCUITRY - The present invention is directed to non-lithographic patterning by laser (or similar-type energy beam) ablation, where the ablation system ultimately results in circuitry features that are relative free from debris induced over-plating defects (debris relating to the ablation process) and fully additive plating induced over-plating defects. Compositions of the invention include a circuit board precursor having an insulating substrate and a cover layer. The insulating substrate is made from a dielectric material and also a metal oxide activatable filler. The cover layer can be sacrificial or non-sacrificial and is used to remediate unwanted debris arising from the ablation process.01-14-2010
20100181284METHOD OF OBTAINING ELECTRONIC CIRCUITRY FEATURES - The present disclosure relates to a method of obtaining fine circuitry features by positioning a circuit board precursor, the circuit board precursor having a cover layer and an insulating substrate, in proximity to a source of laser radiation. Selectively laser ablating through the cover layer and into the underlying insulating substrate and then treating with water, dilute alkali solution or dilute acid solution to remove the cover layer to reveal one or more circuitry features on the insulating substrate that are smaller than if a cover layer is not used.07-22-2010
20100193950WAFER LEVEL, CHIP SCALE SEMICONDUCTOR DEVICE PACKAGING COMPOSITIONS, AND METHODS RELATING THERETO - The invention relates generally to wafer level, chip scale semiconductor device packaging compositions capable of providing high density, small scale circuitry lines without the use of photolithography. The wafer level package comprises a stress buffer layer containing a polymer binder and a spinel crystal filler in both a non-activated and a laser activated form. The stress buffer layer is patterned with a laser to thereby activate the filler, and the laser ablation path can then be selectively metalized.08-05-2010
20100263919Substrates for Electronic Circuitry Type Applications - An electronic type substrate having 40 to 97 weight-percent polymer and 3 to 60 weight-percent auto-catalytic crystalline filler. An interconnect or a conductor trace is created in the substrate by: i. drilling or ablating with a high energy electromagnetic source, such as a laser, thereby selectively activating the multi cation crystal filler along the surface created by the drilling or ablating step; and ii. metalizing by electroless and/or electrolytic plating into the drilled or ablated portion of the substrate, where the metal layer is formed in a contacting relationship with the activated multi cation crystal filler at the interconnect boundary without a need for a separate metallization seed layer or pre-dip.10-21-2010
20110302778COMPOSITIONS AND METHODS FOR CREATING ELECTRONIC CIRCUITRY - The present invention is directed to non-lithographic patterning by laser (or similar-type energy beam) ablation, where the ablation system ultimately results in circuitry features that are relative free from debris induced over-plating defects (debris relating to the ablation process) and fully additive plating induced over-plating defects. Compositions of the invention include a circuit board precursor having an insulating substrate and a cover layer. The insulating substrate is made from a dielectric material and also a metal oxide activatable filler. The cover layer can be sacrificial or non-sacrificial and is used to remediate unwanted debris arising from the ablation process.12-15-2011

Patent applications by Yueh-Ling Lee, Raleigh, NC US