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Lee, CT
Andrew G. Lee, Old Lyme, CT US
| Patent application number | Description | Published |
|---|---|---|
| 20090264413 | Compositions and Methods for Treating Female Sexual Dysfunction - This invention relates to methods, pharmaceutical compositions and kits useful in treating female sexual dysfunction and the use of an estrogen agonist/antagonist for the manufacture of a medicament for the treatment of female sexual dysfunction. The compositions are comprised of an estrogen agonist/antagonist as a first active ingredient and a cyclic guanosine 3′,5′-monophosphate elevator as a second active component and a pharmaceutically acceptable vehicle, carrier or diluent. The compositions and methods of treatment are effective while substantially reducing the concomitant liability of adverse effects associated with estrogen administration. | 10-22-2009 |
| 20100204294 | Methods For Assessing, Improving, Or Maintaining Urogenital Health in Postmenopausal Woman - This invention relates to methods and kits useful for improving or maintaining urogenital health using an estrogen agonist/antagonist. The methods of treatment are effective for improving or maintaining urogenital health while substantially reducing the concomitant liability of adverse effects associated with estrogen administration. This invention also relates to methods of assessing vaginal health. | 08-12-2010 |
| 20110212972 | Compositions and Methods for Treating Female Sexual Dysfunction - This invention relates to methods, pharmaceutical compositions and kits useful in treating female sexual dysfunction and the use of an estrogen agonist/antagonist for the manufacture of a medicament for the treatment of female sexual dysfunction. The compositions are comprised of an estrogen agonist/antagonist as a first active ingredient and a cyclic guanosine 3′,5′-monophosphate elevator as a second active component and a pharmaceutically acceptable vehicle, carrier or diluent. The compositions and methods of treatment are effective while substantially reducing the concomitant liability of adverse effects associated with estrogen administration. | 09-01-2011 |
Ann B. Lee, Hamden, CT US
| Patent application number | Description | Published |
|---|---|---|
| 20090299975 | SYSTEM AND METHOD FOR DOCUMENT ANALYSIS, PROCESSING AND INFORMATION EXTRACTION - The present invention is directed to a method and computer system for representing a dataset comprising N documents by computing a diffusion geometry of the dataset comprising at least a plurality of diffusion coordinates. The present method and system stores a number of diffusion coordinates, wherein the number is linear in proportion to N. | 12-03-2009 |
| 20120047123 | SYSTEM AND METHOD FOR DOCUMENT ANALYSIS, PROCESSING AND INFORMATION EXTRACTION - The present invention is directed to a method and computer system for representing a dataset comprising N documents by computing a diffusion geometry of the dataset comprising at least a plurality of diffusion coordinates. The present method and system stores a number of diffusion coordinates, wherein the number is linear in proportion to N. | 02-23-2012 |
Christine Marie Nixon Lee, Oakville, CT US
| Patent application number | Description | Published |
|---|---|---|
| 20080259996 | METHOD OF SIGNALLING TEMPERATURE AND/OR BENEFIT AGENT RELEASE USING BAR COMPOSITION COMPRISING THERMOCHROMIC PIGMENT OR DYE - The invention relates to method of signaling temperature and/or benefit agent release using bar compositions comprising thermochromatic pigment or dye. In a preferred embodiment, the pigment is introduced in the form of a separate domain (e.g., separate chips) which separate chip or chips is combined with a surfactant-containing chips to form the final bar. | 10-23-2008 |
| 20080261843 | BAR COMPOSITION COMPRISING THERMOCHROMIC PIGMENT OR DYE SIGNALLING BENEFIT AGENT RELEASE OR OTHER USE - The invention relates to bar compositions comprising thermochromatic pigment or dye signaling temperature and/or benefit agent release. In a preferred embodiment, the pigment is introduced in the form of a separate domain (e.g., separate chips) which separate chip or chips is combined with a surfactant-containing chips to form the final bar. | 10-23-2008 |
Chun Geun Lee, New Haven, CT US
| Patent application number | Description | Published |
|---|---|---|
| 20100104570 | Semaphorin 7A Plays a Critical Role in TGF-Beta1-Induced Pulmonary Fibrosis and Alveolar Destruction - The present invention provides methods of treating a subject diagnosed with, or at risk for developing, pathogenic fibrosis, particularly pulmonary fibrosis. The method of the invention comprises administering to the subject a compound or composition which inhibits semaphorin (SEMA) 7A, SEMA 7A receptors, or downstream effectors. A SEMA 7A inhibitor comprises an antibody, a soluble SEMA 7A receptor, an siRNA, a ribozyme, an antisense, an aptamer, a peptidomimetic, a small molecule, a soluble receptor, or any combinations thereof. | 04-29-2010 |
Chun Geun Lee, Orange, CT US
| Patent application number | Description | Published |
|---|---|---|
| 20100247538 | IL-18 and Protein Kinase R Inhibition for the Treatment of COPD - The present invention encompasses compositions and methods directed to preventing, inhibiting, or treating inflammation, alveolar remodeling, or cell death in lung which results from elevation of IL-18, IFN-γ, or PKR where the methods of the present invention comprise administering an IL-18 inhibitor, an IL-18Rα inhibitor, and IFNγ inhibitor, a PKR inhibitor, and any combination thereof to an individual experiencing inflammation, alveolar remodeling, or cell death in lung. The present invention further encompasses a method of alleviating exacerbations of COPD frequently caused by viral infection by administering inflammation, alveolar remodeling, or cell death in lung to a patient with COPD at risk of developing a viral infection or who has acquired a viral infection. | 09-30-2010 |
Daniel R. Lee, Madison, CT US
| Patent application number | Description | Published |
|---|---|---|
| 20100016966 | Tissue Repair Device And Apparatus And Method For Fabricating Same - A method for fabricating a device for repairing torn tissue or muscle such as the meniscus of the knee. The device includes a pair of anchoring members having a plurality of barb-like projections extending outwardly therefrom. The anchoring members are joined by a flexible linking member which connects the ends of the anchoring members opposite one another. Such a device can be fabricated by insert molding of the appropriate members together. | 01-21-2010 |
David K., Lee, Monroe, CT US
| Patent application number | Description | Published |
|---|---|---|
| 20080301184 | System and Method for Updating Mailing Lists - According to some embodiments, a system and method are provided to receive an indication from a postal recipient that an unsolicited mail piece is not desired, the indication comprising a digital image of at least a portion of the unsolicited mail piece, store data associated with the postal recipient based on one or more identifiers, and provide the data associated with the postal recipient to one or more mailers to indicate that the postal recipient requests to opt-out from future mailings. | 12-04-2008 |
| 20090005901 | Payment system for delivery services - According to some embodiments a system and a method are provided to assign a variable receptacle identifier to a mailbox, determine the variable receptacle identifier assigned to a mailbox at the time of delivery, receive delivery data regarding delivery of a mail piece to the mailbox at the time of the delivery, the delivery data including receptacle identification data, and compare the receptacle identification data with the variable receptacle identifier determined as of the particular time. This technique may allow for automatic confirmation that the mail piece was delivered to, or, at least present at, the destination mailbox at the time of delivery claimed by the mail carrier this may provide enhanced capabilities for auditing performance by mail carriers. | 01-01-2009 |
Dennis Lee, Milford, CT US
| Patent application number | Description | Published |
|---|---|---|
| 20100318190 | Methods for Injecting a Curable Biomaterial into an Intervertebral Space - A method for treating a diseased or damaged spinal disc comprises the steps of: (a) providing access to the nucleus pulposus through the annulus; (b) removing at least a portion of the nucleus pulposus to create an intradiscal space; (c) determining the size of the intradiscal space; and (d) sealably introducing under pressure a curable biomaterial through the annulus directly into the intradiscal space. The step of determining the size of the intradiscal space may be accomplished by expanding a compliant balloon within the intradiscal space using a contrast medium capable of visualization under fluoroscopy. The curable material is sealably introduced through a vented needle inserted through the opening. The curable biomaterial is introduced until a quantity of the material flows into the vent. | 12-16-2010 |
Herbert M. Lee, New Fairfield, CT US
| Patent application number | Description | Published |
|---|---|---|
| 20080270225 | Apparatus and Methods for Determining Availability and Performance of Entities Providing Services in a Distributed System Using Filtered Service Consumer Feedback - The invention concerns apparatus and methods that determine availability and performance of entities providing services in a distributed system using filtered service-consumer feedback. In particular, apparatus and methods of the invention filter service-consumer feedback in order to reduce the effect of circumstances unique to individual service consumers or to groups of service consumers that do not accurately reflect the actual availability or performance of service-providing entities. In this way an accurate appraisal is gained regarding the performance and availability of a service-providing entity. Reactive methods of the invention can be combined with proactive methods such as, for example, active status probing, to further improve the accuracy of data concerning the status and availability of service-providing entities. | 10-30-2008 |
Jaeseon Lee, Glastonbury, CT US
| Patent application number | Description | Published |
|---|---|---|
| 20120006511 | ACTIVE STRUCTURES FOR HEAT EXCHANGER - A heat exchanger includes a plurality of channels and one or more active flow disruption members disposed at an entrance to the plurality of channels. The active flow disruption members are configured to induce unsteadiness in a flow through the plurality of channels to increase thermal energy transfer in the plurality of channels. A method for transferring thermal energy from a heat exchanger includes locating one or more active flow disruption members at an entrance to a plurality of channels of the heat exchanger. A flow is directed across the one or more active flow disruption members into the plurality of channels and an unsteadiness is produced in the flow via the one or more active flow disruption members. The unsteadiness in the flow increases the transfer of thermal energy between the heat exchanger and the flow. | 01-12-2012 |
James Sun-Ming Lee, West Hartford, CT US
| Patent application number | Description | Published |
|---|---|---|
| 20110213626 | SYSTEM AND METHOD FOR EFFICIENT CLAIM ASSIGNMENT - A system includes a data storage device configured to receive and store policy information associated with an insurance policy, and a first data structure associating each of a plurality of program identifiers with a respective claim handling identifier, a computer processor configured to execute program instructions and retrieve the policy information from the data storage device, and a memory, coupled to the computer processor, configured to store program instructions for execution by the computer processor. | 09-01-2011 |
Jeongkyu Lee, Trumbull, CT US
| Patent application number | Description | Published |
|---|---|---|
| 20100150416 | METHOD AND SYSTEM FOR PROCESSING VISUAL IMAGES OF DIGESTIVE SYSTEM - The present invention provides a method and system for processing visual images of a digestive system. The method comprises: detecting visual images of a digestive system; storing the detected visual images; analyzing the stored visual images to identify corresponding event frames; and displaying the identified event frames quantitatively with respect to at least one reference. With the method and system, visual images of a digestive system can be processed more accurately, efficiently and conveniently for diagnostic purposes. | 06-17-2010 |
Jeremiah C. Lee, Coventry, CT US
| Patent application number | Description | Published |
|---|---|---|
| 20100242736 | PRESSURE-BASED DISSOLVED GAS REMOVAL SYSTEM - A fuel gas removal system includes a venturi for reducing a pressure of the fuel, a bubble separator containing media to assist in the formation of gas bubbles within the fuel to separate the gas bubbles from the fuel, and a port to remove gas bubbles created by the reduction of pressure of the fuel and the bubble separator. | 09-30-2010 |
Jiang-Ming Lee, Monroe, CT US
| Patent application number | Description | Published |
|---|---|---|
| 20080229446 | Plant 1-deoxy-D-xylulose 5-phosphate reductoisomerase - This invention relates to an isolated nucleic acid fragment encoding a 1-deoxy-D-xylulose 5-phosphate reductoisomerase. The invention also relates to the construction of a chimeric gene encoding all or a portion of the 1-deoxy-D-xylulose 5-phosphate reductoisomerase, in sense or antisense orientation, wherein expression of the chimeric gene results in production of altered levels of the 1-deoxy-D-xylulose 5-phosphate reductoisomerase in a transformed host cell. | 09-18-2008 |
Jianming Lee, Monroe, CT US
| Patent application number | Description | Published |
|---|---|---|
| 20120122936 | LEAVE-ON NONSOLID SKIN CONDITIONING COMPOSITIONS CONTAINING 12-[(12-HYDROXYOCTADECANOYL)OXY] OCTADECANOIC ACID - Leave-on non-solid skin conditioning compositions containing 12-[(12-hydroxyoctadecanoyl)oxy]octadecanoic acid. 12[(12-hydroxyoctadecanoyl)oxy]octadecanoic acid can be easily incorporated in combination with lipophilic carriers that are liquid at room temperature. Compositions are able to deliver increased energy production by human fibroblasts. Preferred compositions also contain 12-hydroxy stearic acid and thus are able to deliver a wide range of skin benefits. | 05-17-2012 |
Jian-Ming Lee, Monroe, CT US
| Patent application number | Description | Published |
|---|---|---|
| 20090054247 | POLYNUCLEOTIDES ENCODING PROTEINS INVOLVED IN PLANT METABOLISM - The invention provides isolated pyruvate dehydrogenase kinase nucleic acids and their encoded polypeptides. The present invention provides methods and compositions relating to altering pyruvate dehydrogenase kinase levels in plants. The invention further provides recombinant expression cassettes, host cells, transgenic plants, and antibody compositions. | 02-26-2009 |
| 20100242137 | POLYNUCLEOTIDES ENCODING PROTEINS INVOLVED IN PLANT METABOLISM - The invention provides isolated pyruvate dehydrogenase kinase nucleic acids and their encoded polypeptides. The present invention provides methods and compositions relating to altering pyruvate dehydrogenase kinase levels in plants. The invention further provides recombinant expression cassettes, host cells, transgenic plants, and antibody compositions. | 09-23-2010 |
| 20110214204 | POLYNUCLEOTIDES ENCODING PROTEINS INVOLVED IN PLANT METABOLISM - The invention provides isolated pyruvate dehydrogenase kinase nucleic acids and their encoded polypeptides. The present invention provides methods and compositions relating to altering pyruvate dehydrogenase kinase levels in plants. The invention further provides recombinant expression cassettes, host cells, transgenic plants, and antibody compositions. | 09-01-2011 |
Jonathan A. Lee, Milford, CT US
| Patent application number | Description | Published |
|---|---|---|
| 20090064453 | Retractable eraser with bristles - A retractable eraser has an elongated contoured housing which has a longitudinal slot and spaced detents and an opening at one end. A carrier has a button which is depressible so that a catch clears the detents to permit selective longitudinal displacement of the carrier. An oval shaped eraser element is mounted to the carrier and displaced into and out of the housing so as, in one position, to project beyond the housing. Bristles project longitudinally from the housing around the opening. | 03-12-2009 |
| 20090064509 | Manually operated hole punch - A manually operated single hole punch employs a pair of pivoted members having squeezable handles. A pair of opposed jaws have canopies formed from transparent or semi-transparent material to facilitate alignment of the punch with the material to be punched and to observe a reservoir which receives punched remnants. | 03-12-2009 |
| 20090067912 | Pencil sharpener with eraser - A pencil sharpener case has a rotatable cover which covers a mechanical pencil sharpener. In one position, the cover may be rotatably retracted to provide access to the pencil sharpener. The case also mounts an eraser which may be used when the pencil sharpener is covered. | 03-12-2009 |
| 20100096286 | Case for first aid supplies - A case for first aid supplies has a housing is enclosed by a lid and is adapted to be both portable and mountable to a wall. The lid is an integral one piece member which includes a latch mechanism as well as an engagement strip for joining with the housing. An integral living hinge allows the lid to pivot. A stop mechanism limits the pivoting of the lid so that a tray may be formed. | 04-22-2010 |
| 20100096350 | Rack/module assembly for first aid supplies - A rack/module assembly for first aid supplies comprises a plurality of modules which are insertable into a receptacle of a rack. Each module is semi-transparent or transparent and has a front cover portion which is pivotal to provide access to first aid supplies within the module enclosure. An integral latch mechanism releasably latches the cover in a closed position. Each of the modules contains first aid supplies specific to a given first aid treatment. | 04-22-2010 |
| 20100212781 | Pencil sharpener - A pencil sharpener has an electrical motor which drives a sharpening assembly. The end of the pencil to be sharpened is inserted downwardly into an opening in the top surface. Shavings from the sharpening process are deposited in a drawer-like receptacle below the sharpening assembly. A switch is provided so that the sharpening assembly will not be activated when the receptacle drawer is removed for disposal of the shavings. | 08-26-2010 |
| 20110119928 | Cutting Implement with Cartridge - A utility knife has a receiving cavity which opens through the body. A cartridge comprising a magazine of blades is removably insertable into the receiving cavity. A carrier within the body is manually operable for receiving a blade from the cartridge and positioning the blade for extension through the opening to present a cutting edge. The cartridge may be released from the utility knife body by depressing a button and withdrawing the cartridge. The cartridge is releasably held in place within the knife body and releasable when the blade carrier is in its retracted position and the release button is depressed. When the thumb button moves the blade carrier into its extended position to expose the knife blade, the cartridge is rendered unreleaseable even if the release button is depressed. The release button, which will enable removal of the magazine when depressed and blade carrier is in its retracted position, also serves to release of the blade from the blade carrier to permit removal of a used blade from the knife body when the blade carrier is in its extended position. | 05-26-2011 |
Keat Jin Lee, Guilford, CT US
| Patent application number | Description | Published |
|---|---|---|
| 20100121653 | METHOD FOR TRACKING AND SORTING MEDICAL TEST INFORMATION - In a method for tracking medical test information a content database is established and is cooperable with software, the content database being populable with identifying information relevant to particular patients and care providers. Information relevant to tests performed or to be performed on one or more of the patients is received and associated with the patient. The information stored in the database and retrievable therefrom, includes; the type of test, who ordered a particular test, when it is ordered, when was the scheduling done for the test, who scheduled it, when was the test scheduled to be performed, when was it performed, what was the expected date of the test results, when did the results actually become available, when were the test results read, when were the test results conveyed to the patient, and when did the final disposition occur. The software being operable to sort at least a portion of said information upon request by a user. | 05-13-2010 |
| 20100138496 | METHOD FOR DIGITALLY RECORDING PROGRESS NOTES - A computer implemented method for digitally recording progress notes, including establishing a content database cooperable with software, the content database being populable with identifying information relevant to patients and care providers. The software is customizable such that a user can input items to be displayed on a screen and is operable to cause questions and the allowable answers thereto to be displayed. The software is customizable to allow a user to determine at least a portion of the questions and the answers that are displayed and is operable to cause text to be input into a letter. The software is customizable to allow a user to determine at least a portion of the text that will be input into the letter upon selection of at least a portion of the answers and is operable to generate the letters in accordance with the answers chosen by a user. | 06-03-2010 |
| 20100169383 | METHOD FOR DIGITALLY RECORDING INFORMATION - In a computer implemented method for digitally recording progress notes a content database cooperable with software can be populated with information relevant to patients and care providers. A User can select items displayed on a screen of a communications device. The software operates to generate information mandated by one or more certifying authorities by causing questions pertaining to the mandated information and selectable answers to the questions to be displayed on the screen. At least a portion of the questions displayed are dependant on the answers chosen by the user during operation of the communications device. The selected information is received into the content database. | 07-01-2010 |
| 20100191070 | DIAGNOSTIC METHOD INCLUDING UNIFORM ENCODING OF INFORMATION - A diagnostic encoding method is provided. The method includes assigning a first plurality of identifiers to an anatomical structure of the human body and assigning a second plurality of identifiers to diagnostic criterion by which caregivers evaluate patients. The method further includes, when diagnosing a patient, recording findings of the diagnosis of the patient using at least one of each of the first plurality and the second plurality of identifiers. In one embodiment, the first plurality of identifiers includes a first subset of identifiers identifying each organ in the human body (e.g., a right ear) and a second subset of identifiers identifying component parts of each of the organs in the first subset (e.g., an ear drum of the right ear). In one embodiment, the second plurality of identifiers includes a third subset of identifiers identifying symptoms relating to the first and the second identifiers. | 07-29-2010 |
Kyle M. Lee, Ellington, CT US
| Patent application number | Description | Published |
|---|---|---|
| 20110320223 | SYSTEM AND METHOD FOR ANALYSIS OF INSURANCE CLAIMS - A computer system for analyzing insurance claim data is configured to receive data relating to a current insurance claim from a client device; query a database for data relating to insurance claims similar to the current claim; receive from the database data relating to insurance claims responsive to the query; analyze the received data; generate a display of the analyzed received data and communicate the generated display to the client device for display on the client device. The display may include a value of recoveries within the time window as a proportion of initial demands for settled similar claims and a value of recoveries within the time window as a proportion of initial demands for arbitrated similar claims. | 12-29-2011 |
Kyungae Lee, Guilford, CT US
| Patent application number | Description | Published |
|---|---|---|
| 20100267698 | Benzimidazole and Pyridylimidazole Derivatives - This invention relates to benzimidazoles, pyridylimidazoles and related bicyclic heteroaryl compounds, all of which may be described by of Formula I | 10-21-2010 |
Minjoo Lee, New Haven, CT US
| Patent application number | Description | Published |
|---|---|---|
| 20110187412 | COMPLEMENTARY METAL OXIDE SEMICONDUCTOR DEVICES - Improvements in Complementary Metal Oxide Semiconductor (CMOS) devices; in particular, field effect transistors (FETs) and devices using said transistors which are able to take advantage of the higher carrier mobility of electrons compared to holes by replacing the conventional p-channel transistor with an n-channel transistor having a double gate (or vice versa): Such a Unipolar CMOS (U-CMOS) transistor can be realised by adapting the source and/or the drain such that when the body region undergoes inversion at a first surface current, is able to flow between the drain and the source and when the body region undergoes inversion at a second surface current is not able to flow between the drain and the source. Various logic gates may be constructed using U-CMOS transistors. | 08-04-2011 |
Minjoo L. Lee, Hamden, CT US
| Patent application number | Description | Published |
|---|---|---|
| 20090114902 | TENSILE STRAINED GE FOR ELECTRONIC AND OPTOELECTRONIC APPLICATIONS - A semiconductor structure is provided. The semiconductor structure includes one or more III-IV material-based semiconductor layers. A tensile-strained Ge layer is formed on the one or more a III-IV material-based semiconductor layers. The tensile-strained Ge layer is produced through lattice-mismatched heteroepitaxy on the one or more a III-IV material-based semiconductor layers. | 05-07-2009 |
Nathanael Thomas Lee, Essex, CT US
| Patent application number | Description | Published |
|---|---|---|
| 20080250719 | Locking System for Windows and Doors - A lock system for casement windows is disclosed which includes a tie bar slidably secured to the flame. The tie bat is secured to a lock handle that is also secured to the flame. The tie bat eliminates the need for rollers riveted to the tie bar by having a first bent section disposed between straight sections and a second bent section disposed between straight sections. All of the straight sections are linearly aligned with one another and at least some of the straight sections of the tie bar are slidably mounted to the flame using conventional guides. The lock system also includes first and second strikers mounted to the sash. The first striker comprising a first ramp that receives a first bent section and the second striker comprising a second ramp that receives a second bent section when the tie bat is slidably moved towards the first and second strikers as the tie bar is moved from an unlocked position to a locked position. Movement of the first and second bent sections along the first and second ramps respectively as the tie bar moves towards the locked position results in the sash and frame being pulled together. A third bent section may be included towards the middle of the tie bar and used to couple the tie bar to the lock handle or actuator. | 10-16-2008 |
Patty Lee, Guilford, CT US
| Patent application number | Description | Published |
|---|---|---|
| 20080318895 | INTRANASAL DELIVERY OF NUCLEIC ACID MOLECULES - Aerosol delivery of nucleic acids to the lungs using viral vectors, polymers, surfactants, or excipients has been described. Compositions for intranasal administration are described that contain nucleic acids without viral or plasmid vectors and with little to no polymers, surfactants, or excipients. In one embodiment, the composition for intranasal delivery consists essentially of at least one nucleic acid and an aqueous solution. Suitable nucleic acids for intranasal delivery include, but are not limited to, dsDNA, dsRNA, ssDNA, ssRNA, short interfering RNA, micro-RNA, and antisense RNA Methods for treatment, diagnosis, or prevention of at least one symptom or manifestation of a lung disease are also described consisting of administration by intranasal delivery an effective amount of a composition containing a nucleic acid. The composition may be formulated as a liquid or aerosol or other acceptable formulation for intranasal administration. | 12-25-2008 |
| 20100086546 | Toll-LIke Receptor 4 Deficiency and Downstream Effectors Cause Pulmonary Emphysema - The present invention provides compositions and methods for the detection, treatment, and prevention of emphysema/COPD. Compositions of the present invention comprise TLR4 activators, Nox3 inhibitors, and Cathepsin E inhibitors useful in the treatment or prevention of emphysema/COPD. Cathepsin E is a downstream effector of TLR4, wherein when cathepsin E is overexpressed in lung of an individual, the individual is at higher risk of developing emphysema/COPD. Cathepsin E is further identified as a biomarker useful in the identification of an individual with, or at-risk of developing emphysema/COPD. | 04-08-2010 |
Robert A. Lee, Simsbury, CT US
| Patent application number | Description | Published |
|---|---|---|
| 20100037793 | DETONATING CORD AND METHODS OF MAKING AND USING THE SAME - The velocity of detonation of an explosive such as detonating cord ( | 02-18-2010 |
Seung Lee, Branford, CT US
| Patent application number | Description | Published |
|---|---|---|
| 20110301145 | PYRIDAZINONES, METHOD OF MAKING, AND METHOD OF USE THEREOF - Compounds of Formula I that inhibit Btk are described herein. Pharmaceutical compositions comprising at least one compound of Formula I, together with at least one pharmaceutically acceptable vehicle chosen from carriers, adjuvants, and excipients, are described. Methods of treating patients suffering from certain diseases responsive to inhibition of Btk activity and/or B-cell activity are described. Methods for determining the presence of Btk in a sample are described. | 12-08-2011 |
Seung H. Lee, Branford, CT US
| Patent application number | Description | Published |
|---|---|---|
| 20090082330 | CERTAIN SUBSTITUTED AMIDES, METHOD OF MAKING, AND METHOD OF USE THEREOF - Compounds of Formula I that inhibit Btk are described herein. Pharmaceutical compositions comprising at least one compound of Formula I, together with at least one pharmaceutically acceptable vehicle chosen from carriers, adjuvants, and excipients, are described. Methods of treating patients suffering from certain diseases responsive to inhibition of Btk activity and/or B-cell activity are described. Methods for determining the presence of Btk in a sample are described. | 03-26-2009 |
| 20100152159 | IMIDAZOPYRAZINE SYK INHIBITORS - Certain imidazopyrazines and pharmaceutical compositions thereof are provided herein. Methods of treating patients suffering from certain diseases and disorders responsive to the inhibition of Syk activity, which comprises administering to such patients an amount of at least one chemical entity effective to reduce signs or symptoms of the disease or disorder are provided. Also provided are methods for determining the presence or absence of Syk kinase in a sample. | 06-17-2010 |
| 20100222323 | IMIDAZOPYRAZINE SYK INHIBITORS - Certain imidazopyrazines and pharmaceutical compositions thereof are provided herein. Methods of treating patients suffering from certain diseases and disorders responsive to the inhibition of Syk activity, which comprises administering to such patients an amount of at least one chemical entity effective to reduce signs or symptoms of the disease or disorder are provided. Also provided are methods for determining the presence or absence of Syk kinase in a sample. | 09-02-2010 |
| 20110059944 | Certain Substituted Amides, Method of Making, and Method of Use Thereof - Compounds of Formula I that inhibit Btk are described herein. Pharmaceutical compositions comprising at least one compound of Formula I, together with at least one pharmaceutically acceptable vehicle chosen from carriers, adjuvants, and excipients, are described. Methods of treating patients suffering from certain diseases responsive to inhibition of Btk activity and/or B-cell activity are described. Methods for determining the presence of Btk in a sample are described. | 03-10-2011 |
| 20110118233 | Certain Substituted Amides, Method of Making, and Method of Use Thereof - Compounds of Formula I that inhibit Btk are described herein. Pharmaceutical compositions comprising at least one compound of Formula I, together with at least one pharmaceutically acceptable vehicle chosen from carriers, adjuvants, and excipients, are described. Methods of treating patients suffering from certain diseases responsive to inhibition of Btk activity and/or B-cell activity are described. Methods for determining the presence of Btk in a sample are described. | 05-19-2011 |
| 20120010191 | PYRIDONE AND AZA-PYRIDONE COMPOUNDS AND METHODS OF USE - Pyridone and aza-pyridone compounds of Formula I are provided, including stereoisomers, tautomers, and pharmaceutically acceptable salts thereof, useful for inhibiting Btk kinase, and for treating immune disorders such as inflammation mediated by Btk kinase. Methods of using compounds of Formula I for in vitro, in situ, and in vivo diagnosis, and treatment of such disorders in mammalian cells, or associated pathological conditions, are disclosed. | 01-12-2012 |
Seung H. Lee, Brandord, CT US
| Patent application number | Description | Published |
|---|---|---|
| 20100160292 | Kinase Inhibitors, and Methods of Using and Identifying Kinase Inhibitors - Methods of inhibiting BTK activity by inhibiting phosphorylation of Y551 of BTK, methods of treating patients by inhibiting BTK activity by inhibiting phosphorylation of Y551 of BTK, chemical entities that bind to BTK and inhibited complexes are provided. | 06-24-2010 |
Shinghoi Lee, West Windsor, CT US
| Patent application number | Description | Published |
|---|---|---|
| 20100262439 | System And Method For Pricing Default Insurance - A system for modeling a basket of securities containing a plurality of securities is provided and includes a default/recovery model database for storing default/recovery data regarding the plurality of securities. Also included is a default simulation engine for calculating a default time for at least one of the plurality of securities based on the default/recovery data. Finally, a cash flow engine is included for generating cash flows for the basket of securities based on the default times. | 10-14-2010 |
Stephen P. Lee, Hamden, CT US
| Patent application number | Description | Published |
|---|---|---|
| 20100168939 | MODULE FOR INTEGRATED APPROACH TO AN OFFSHORE FACILITY - A system and method to facilitate approach of a VTOL aircraft to an offshore facility includes inputting a waypoint for a landing platform of an offshore facility into an aircraft module, inputting an offset distance from the landing platform into the aircraft module, inputting a minimum descent height into an aircraft module, and inputting a final approach inbound course toward the landing platform into the aircraft module. | 07-01-2010 |
Steven Lee, Stamford, CT US
| Patent application number | Description | Published |
|---|---|---|
| 20080228581 | Method and System for a Natural Transition Between Advertisements Associated with Rich Media Content - A method includes receiving a plurality of a plurality of candidate segmentation points associated with a portion of rich media content, selecting a subset of the candidate segmentation points that meet one or more segmentation constraints, where the selected subset of segmentation points define a plurality of temporal segments of the rich media content, and providing the selected subset of segmentation points for association of a different one of a plurality of advertisements with each of the temporal segments. | 09-18-2008 |
Terrence Lee, Norwalk, CT US
| Patent application number | Description | Published |
|---|---|---|
| 20120084353 | ONLINE WAITING ROOM SYSTEM, METHOD & COMPUTER PROGRAM PRODUCT - An exemplary embodiment of the present invention sets forth a system, method and computer program product which may include providing an online waiting room and gatekeeper for controlling access to users in a plurality of tiered classification standby lines, seeking access to an online event. | 04-05-2012 |
Thomas Wai-Ho Lee, Brookfield, CT US
| Patent application number | Description | Published |
|---|---|---|
| 20090325988 | Glucocorticoid Mimetics, Methods of Making Them, Pharmaceutical Compositions and Uses Thereof - Compounds of Formula (I) | 12-31-2009 |
| 20100093724 | Azaindazole Compounds As CCR1 Receptor Antagonists - Disclosed are compounds of the formula (I), useful for treating a variety of diseases and disorders that are mediated or sustained through the activity of CCR1 including autoimmune diseases, such as rheumatoid arthritis and multiple sclerosis. | 04-15-2010 |
| 20110086846 | Azaindazole Compounds As CCR1 Receptor Antagonists - Disclosed are compounds of the formula (I), useful for treating a variety of diseases and disorders that are mediated or sustained through the activity of CCR1 including autoimmune diseases, such as rheumatoid arthritis and multiple sclerosis. | 04-14-2011 |
| 20120035370 | Azaindazole Compounds As CCR1 Receptor Antagonists - Disclosed are compounds of the formula (I), useful for treating a variety of diseases and disorders that are mediated or sustained through the activity of CCR1 including autoimmune diseases, such as rheumatoid arthritis and multiple sclerosis. | 02-09-2012 |
Thomas Wai-Ho Lee, Danbury, CT US
| Patent application number | Description | Published |
|---|---|---|
| 20090176807 | GLUCOCORTICOID MIMETICS, METHODS OF MAKING THEM, PHARMACEUTICAL COMPOSITIONS, AND USES THEREOF - Compounds of Formula (I) | 07-09-2009 |
William L. Lee, Madison, CT US
| Patent application number | Description | Published |
|---|---|---|
| 20110177587 | NUCLEIC ACID AMPLIFICATION WITH CONTINUOUS FLOW EMULSION - Embodiments of the present invention are directed to methods and devices/systems for amplifying genetic material and may include providing a water-in-oil emulsion in a continuous flow. The emulsion may include a plurality of water droplets comprising microreactors. Each of the plurality of microreactors may include a single bead capable of capturing a nucleic acid template, a single species nucleic acid template and sufficient reagents to amplify the copy number of the nucleic acid template. The method also includes flowing the emulsion across a first temperature zone and a second lower temperature zone to thermally process the microreactors to amplify the nucleic acid template by polymerase chain reaction. | 07-21-2011 |
Yi Pei Lee, New Britain, CT US
| Patent application number | Description | Published |
|---|---|---|
| 20080229509 | CONVERTIBLE MATTRESS SYSTEM FOR HOTELS - A convertible mattress and bedding system includes first and second bed frames and first and second mattresses. At least one of the bed frames is laterally moveable relative to the other of the bed frames from a one bed configuration to a two bed configuration. Each mattress includes first and second longitudinally extending mattress halves. The first mattress half is connected to the second mattress half by a longitudinally extending hinge and is movable from a folded condition, with the first mattress half disposed above the second mattress half, to an open condition, with the first mattress half disposed laterally adjacent the second mattress half. The first mattress is disposed on the first bed frame in a folded condition and the second mattress is disposed on the second bed frame in a folded condition when the bed frames are in the two bed configuration. The first and second mattress are each disposed on the first and second bed frames in an open condition when the bed frames are in the one bed configuration. | 09-25-2008 |