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Lee, Boston

Alan W. Lee, Boston, MA US

Patent application numberDescriptionPublished
20100002739LENS COUPLED QUANTUM CASCADE LASER - Terahertz quantum cascade (QC) devices are disclosed that can operate, e.g., in a range of about 1 THz to about 10 THz. In some embodiments, QC lasers are disclosed in which an optical element (e.g., a lens) is coupled to an output facet of the laser's active region to enhance coupling of the lasing radiation from the active region to an external environment. In other embodiments, terahertz amplifier and tunable terahertz QC lasers are disclosed.01-07-2010

Brian S. Lee, Boston, MA US

Patent application numberDescriptionPublished
20100103717TUNING A VARIABLE RESISTANCE OF A RESISTIVE SENSE ELEMENT - Method and apparatus for tuning a variable resistance resistive sense element of an electronic device. In some embodiments, a value indicative of a selected number of consecutive pulses is stored in a memory location and a resistive sense element (RSE) is set to a baseline RSE resistance. A tuning operation is performed by applying the selected number of consecutive pulses to the RSE to tune the baseline RSE resistance to a final adjusted resistance.04-29-2010

Harry Lee, Boston, MA US

Patent application numberDescriptionPublished
20080299539Parallel integrated bioreactor device and method - In one embodiment, the present invention introduces integrated fluid injection and mixing devices to enable pH control in a miniature parallel integrated bioreactor array system. In another embodiment, the environmental conditions of the growth chamber is enabled through fluidic injections in a miniature parallel cell culture system. In still another embodiment, the present invention utilizes gas switches to control oxygen concentration within a miniature parallel integrated bioreactor array.12-04-2008
20090038417FLUID INJECTION PORT - Fluid injection port. An elastomeric injection nipple is supported within a compression fitting and the injection nipple includes a slit. A first via is provided that connects the slit in the nipple to a flow channel leading into a fluid reservoir. A venting channel is provided in fluid communication with the fluid reservoir and also in fluid communication with a second via. When a pipette is inserted into the slit in the injection nipple, the nipple deforms allowing the second via to be in fluid communication with space on either side of the pipette tip whereby air can be discharged.02-12-2009
20090220935APPARATUS AND METHOD FOR DISSOLVED OXYGEN CONTROL IN PARALLEL INTEGRATED BIOREACTOR ARRAY - Parallel, integrated bioreactor. The bioreactor includes a plurality of growth chambers, each growth chamber associated with a peristaltic oxygenating mixer and separated therefrom by a porous membrane. Each oxygenating mixture has a gas inlet and a gas outlet with the gas inlet in fluid communication with a gas reservoir. A gas mixer switch is provided for controlling oxygen concentration in the reservoir. The apparatus and methods disclosed in the application allow precise control over dissolved oxygen concentration with a quick response time.09-03-2009
20110137381Treatment of neurological disorders via electrical stimulation, and methods related thereto - Disclosed are medical devices for the prevention and/or treatment of neurological disorders via electrical stimulation, and methods related thereto. The devices may also be utilized to detect disorders before the prevention or treatment of a neurological disorder. These devices are minimally or non-invasive. The present medical devices comprise various components, which include electrodes and control electronics. The electrodes are targeting electrodes constructed from ring type structures or virtually connected disc type arrays. The electrodes are located entirely outside the skull. The present medical devices also comprise one or more subsystems, a control system, a battery unit, and wires connecting the one or more subsystems. These devices may also be used for acute seizure control.06-09-2011

Patent applications by Harry Lee, Boston, MA US

Po-Shun Lee, Boston, MA US

Patent application numberDescriptionPublished
20080261260USE OF GELSOLIN TO TREAT INFECTIONS - The invention relates to the use of gelsolin to treat infections and to monitor the treatment of infections. The invention also provides methods up-regulating interleukin expression and methods for down-regulating pro-inflammatory cytokine expression.10-23-2008

Seonkyung Lee, Boston, MA US

Patent application numberDescriptionPublished
20090323743High-Power, High-Throughput Microwave Discharge Singlet Oxygen Generator for Advanced Electrical Oxygen-Iodine Lasers - A laser device includes an optical resonator, a microwave driven discharge device, and a source for a second gas. The microwave driven discharge device is disposed relative to the optical resonator. The microwave driven discharge device operates at a discharge power and gas flow rate to produce a selected amount of energetic singlet oxygen metastables flowing in the direction of the optical resonator. The second source for the second gas is disposed between the optical resonator and the microwave driven discharge device. The second gas reacts with the selected amount of energetic singlet oxygen metastables to form an excited species in an amount sufficient to support lasing of the excited species in the optical resonator.12-31-2009

Soo-Kwan Lee, Boston, MA US

Patent application numberDescriptionPublished
20080242558FABRICATED BIOFILM STORAGE DEVICE - The present invention includes a method and composition of storing and preserving biofilms for input and output of high-density information. One form of the present invention is a fabricated biofilm storage device with a biologic material applied to a substrate to form, e.g., a dry thin film stable at room temperature for extended periods of time. Another form of the present invention is a method of fabricating a biofilm storage device in which a biologic material is applied to a substrate under conditions that promote alignment of the biologic material on the substrate. The composition, method, and kit of the present invention have universal application in biologics, magnetics, optics and microelectronics.10-02-2008

William David Lee, Boston, MA US

Patent application numberDescriptionPublished
20090273878GAS BEARING ELECTROSTATIC CHUCK - An electrostatic clamp is provided having a clamping plate, wherein the clamping plate has a central region and an annulus region. A plurality of gas supply orifices are defined in the central region of the clamping plate, wherein the plurality of gas supply orifices are in fluid communication with a pressurized gas supply, and wherein the pressurized gas supply is configured to provide a cushion of gas between the clamping surface and the workpiece in the central region of the clamping plate via the plurality of gas supply orifices. One or more gas return orifices defined in one or more of the central region and annulus region of the clamping plate, wherein the one or more gas return orifices are in fluid communication with a vacuum source, therein generally defining an exhaust path for the cushion of gas. A seal is disposed in the annulus region of the clamping plate, wherein the seal is configured to generally prevent a leakage of the cushion of gas from the central region to an environment external to the annulus region. One or more electrodes are further electrically connected to a first voltage potential to provide a first clamping force.11-05-2009

William W. Lee, Boston, MA US

Patent application numberDescriptionPublished
20080288917Smart generator - The Smart Generator of the present invention allows the designer/developer/user to model the EJB components in a natural way without being concerned with implementation-specific details. The developer models the business objects using a UML drawing tool and the Smart Generator creates a set of classes that implements these objects with reference to the Enterprise JavaBeans specification. That is, the Smart Generator automatically create access methods and handling containment of references from the UML diagram.11-20-2008