Patent application number | Description | Published |
20080318973 | Urotensin II receptor antagonists - This invention is directed to a compound of Formula (I): | 12-25-2008 |
20100029616 | UROTENSIN II RECEPTOR ANTAGONISTS - The present invention is directed to compounds of formula (I) | 02-04-2010 |
20110105562 | ALKYNYL DERIVATIVES USEFUL AS DPP-1 INHIBITORS - The present invention is directed to novel alkynyl derivatives, pharmaceutical compositions containing them and their use in the treatment of disorders and conditions modulated by DPP-1. | 05-05-2011 |
20110136824 | UROTENSIN II RECEPTOR ANTAGONISTS - The invention is directed to Urotensin II antagonists. More specifically, the present invention relates to certain novel compounds, methods for preparing compounds, compositions, intermediates and derivatives thereof and methods for treating Urotensin-II mediated disorders. Pharmaceutical and veterinary compositions and methods of treating cardiovascular disorders and various other disease states or conditions using compounds of the invention are also described. | 06-09-2011 |
20110152321 | BICYCLIC DERIVATIVES USEFUL AS INHIBITORS OF DPP-1 - The present invention is directed to novel bicyclic derivatives, pharmaceutical compositions containing them and their use in the treatment of disorders and conditions modulated by DPP-1. | 06-23-2011 |
20110269768 | UROTENSIN II RECEPTOR ANTAGONISTS - This invention is directed to a compound of Formula (I): | 11-03-2011 |
20120077847 | ALPHA-KETOAMIDE DERIVATIVES USEFUL ENDOTHELIAL LIPASE INHIBITORS - The present invention is directed to α-ketoamide derivatives, pharmaceutical compositions containing them and their use in the treatment of disorders and conditions modulated by endothelial lipase, for example, cardiovascular disorders. | 03-29-2012 |
20120214817 | UROTENSIN II RECEPTOR ANTAGONISTS - The invention is directed to Urotensin II antagonists. More specifically, the present invention relates to certain novel compounds, methods for preparing compounds, compositions, intermediates and derivatives thereof and methods for treating Urotensin-II mediated disorders. Pharmaceutical and veterinary compositions and methods of treating cardiovascular disorders and various other disease states or conditions using compounds of the invention are also described. | 08-23-2012 |
Patent application number | Description | Published |
20130200194 | IAR DRAG RELEASE - A fishing reel including: a housing with a side plate, a gear stud rotatably disposed relative to the housing to rotate about a first axis, and a main gear concentrically disposed relative to the gear stud. The main gear interacts with another gear to rotate a spool about a second axis. The reel also includes a drag stack concentrically disposed relative to the gear stud, a one way clutch concentrically disposed relative to the gear stud, and a clutch sleeve disposed within and engaging the one-way clutch. The clutch sleeve is constrained to rotate with the gear stud. The reel further includes an adjustment member disposed outside the housing that provides a user interface for adjusting a desired drag, and a drag adjuster that transmits drag adjustments from the adjustment member to the drag stack without axially displacing the clutch sleeve. | 08-08-2013 |
20140257401 | Elastic Member Clamps - The present application generally relates to orthopedic stabilization systems, and in particular, to systems including clamps. The clamps can be used in addition to or to replace hooks that grasp onto bone members, such as the lamina. One example of such a clamp is an in-line clamp that includes a central opening for receiving a rod member, a first opening for receiving a set screw and a second opening for receiving an elastic member therethrough. Another example of such a clamp is an off-set clamp that includes an upper plate, a bottom plate, and an opening for receiving a rod therein. The upper plate can be separated from the bottom plate to make space for an elastic member that can be secured within the plates. Tulip clamps that utilize one or more elastic members are also provided. | 09-11-2014 |
20140296925 | Orthopedic Anchor Assembly - An orthopedic assembly is described that comprises an orthopedic device, an anchor, and a locking mechanism. The orthopedic device can be a plate member having an aperture that is configured to receive the anchor. The anchor can include a head, neck and shank portion. The head portion can include a plurality of arms separated by grooves that are capable of splaying. The assembly is configured such that when the locking mechanism is inserted into the head portion, this causes expansion of the arms of the head. This expansion locks and secures the anchor to the orthopedic device. Various instruments are provided that can deliver the locking mechanism to the anchor, and can provide impact to lock functionality. | 10-02-2014 |
Patent application number | Description | Published |
20090189581 | APPARATUS AND METHOD FOR RECYCLING THE ENERGY FROM LOAD CAPACITANCE - The present invention provides a voltage regulator/power converter capable of bidirectional power propagation, fitted with controls capable of raising and lowering voltages with unprecedented speed and accuracy. The bidirectional capability allows energy stored in capacitors to be returned to system power sources. In one embodiment of the invention power is supplied from a power source (on a first port of the power converter) to the load (on a second port of the power converter) through the converter and then, when load voltage is reduced or turned off, energy in the load capacitance is returned from to the power source. In an alternative embodiment energy from load capacitance is stored or used by a device on a third port of the power converter. | 07-30-2009 |
20100052768 | GATE-CHARGE RETAINING SWITCH - This invention provides a means and method for preventing unwanted semiconductor turn-on and turn-off, caused by a high rate of voltage change, without significantly affecting the desired ON and OFF transitions of the semiconductor. According to this invention, time is provided during either or both bistable ON and OFF semiconductor states, during which the semiconductor gate is allowed to float, neither being driven ON or OFF, and circuitry for lowering gate-node impedance at non-transitional times to prevent state disruptions by dV/dT is provided. | 03-04-2010 |
20100066335 | POWER CONVERSION REGULATOR WITH PREDICTIVE ENERGY BALANCING - A power-conversion regulator comprising an inductive reactor, an output filter reactor, and a switch for admitting energy to the inductive reactor, additionally comprises computation circuitry responsive to the flux in the inductive reactor, to a reference signal, to an output voltage, and sometimes to an output load current, for computing the quantity of energy that must be supplied to a load and to the output filter reactor to regulate the output voltage or current to a desired relationship with the reference signal during each chopping waveform cycle driving the switch. As the inductive reactor is charged from an input energy source, the computation circuitry predicts whether the energy in the inductive reactor has become adequate for the regulation. | 03-18-2010 |
20110115455 | ENERGY PREDICTIVE BUCK CONVERTER - In a switched-mode buck power converter, superior regulation with excellent transient response is provided when per-cycle energy demand is determined and balanced with per-cycle inductive energy supply to control per-cycle inductive energy charging. Such per cycle inductive energy calculation is improved through the prediction of pedestal energy during operating periods of Continuous Conduction Mode (CCM). Further, recovery from severe transients sometimes straddles multiple chopping cycles. Such recovery is best obtained by preserving energy balance information from one or more un-recovered chopping cycles, to be used to restore energy balance in subsequent cycles. Significant improvement over prior art converters may be obtained even when the energy balance data used for control and recovery are imprecise approximations of true energy demand and supply. | 05-19-2011 |
20110122657 | SWITCH WITH COMMON-MODE CHOKE - A common-mode choke level-shifter drives a power switch with sub-nanosecond timing integrity without requiring a high-side gate-drive power supply. The same level-shifter may also be used to drive a low-side switch to avoid ground bounce effects. | 05-26-2011 |
20110187186 | UNIVERSAL SINGLE-STAGE POWER CONVERTER WITH PFC CAPABILITY - A switched-mode power converter power converter, in one preferred embodiment with eight switches connected between three ports and an inductive element, with a donor (charging) port, a receptor port (load) and donor/receptor port (storage) operated so that energy may be switch between any of the ports regardless of the polarity and magnitude of the inductor current at the beginning of a chopping cycle. In one embodiment of the invention power conversion and power factor correction are accomplished in a single stage. | 08-04-2011 |
20130147449 | BI-POLAR BI-DIRECTIONAL ENERGY BALANCING POWER-CONVERSION ENGINE - The invention provides a power converter and method for controlling same, comprising a plurality of switch elements, an inductive reactor, and at least two ports for the movement of electrical energy. Any energy-moving port may be made unipolar, bidirectional, bipolar, or bidirectionally bipolar. Ports may be equipped with sensing circuitry to allow the converter output to be controlled responsively to an input signal. The invention may be configured to be used in many ways, for example, as a power-supply, as an amplifier, or as a frequency converter. The invention may comprise energy predictive calculating means to obtain excellent transient response to line and load variations. The invention may also include a switch to create a low impedance path around the inductor to allow current to recirculate through the inductor when it is not needed at any of the ports. | 06-13-2013 |
20140009975 | POWER CONVERTER WITH DEMAND PULSE ISOLATION - The present invention provides a switched-mode power converter with regulation demand pulses sent across a galvanic isolation barrier. | 01-09-2014 |
20140198545 | POWER-CONVERSION ENGINE - The disclosure provides a power converter and method for controlling same, comprising a plurality of switch elements, an inductive reactor, and at least two ports for the movement of electrical energy. Any energy-moving port may be made unipolar, bidirectional, bipolar, or bidirectionally bipolar. Ports may be equipped with sensing circuitry to allow the converter output to be controlled responsively to an input signal. The disclosure may be configured to be used in many ways, for example, as a power-supply, as an amplifier, or as a frequency converter. The disclosure may comprise energy predictive calculating means to obtain excellent transient response to line and load variations. The disclosure may also include a switch to create a low impedance path around the inductor to allow current to recirculate through the inductor when it is not needed at any of the ports. | 07-17-2014 |
20140232366 | Switched-Mode Compound Power Converter With Main and Supplemental Regulators - In certain embodiments, the present invention provides a compound power converter in which the majority of power passes from input to output through only a single stage of power conversion. At least one embodiment includes a main converter with an auxiliary output. The auxiliary output energizes a reservoir that provides input power for a supplemental converter capable supplying the main output. The supplemental converter improves regulation and can provide holdover power for Power Factor Correction (PFC) or Uninterruptible Power Supply (UPS) operation. | 08-21-2014 |