Patent application number | Description | Published |
20140310390 | ASYMMETRIC PACKET FLOW IN A DISTRIBUTED LOAD BALANCER - A distributed load balancer in which a router receives packets from at least one client and routes packet flows to multiple ingress servers. For unknown packet flows, an ingress server cooperates with primary and secondary flow trackers to establish connections to server nodes. For known packet flows, the ingress server sends the packets to target server nodes. The server nodes randomly select egress servers for outgoing packets of the packet flows. The ingress servers, flow trackers, and egress servers are implemented by multiple load balancer nodes in a load balancer node layer. The ingress and egress servers for a given packet flow may be on different load balancer nodes. The load balancer nodes may use a consistent hash function to compute a consistent hash ring for the nodes according to packet flow client/public endpoint pairs so that nodes associated with given packet flows can be located. | 10-16-2014 |
20140310391 | MULTIPATH ROUTING IN A DISTRIBUTED LOAD BALANCER - A distributed load balancer in which a router receives packets from at least one client and routes packet flows to multiple load balancer nodes. The router exposes a public IP address and the load balancer nodes all advertise the same public IP address to the router. The router may implement a per-flow hashed multipath routing technique, for example an equal-cost multipath (ECMP) routing technique, to distribute the flows across the load balancer nodes. Thus, the multiple load balancer nodes may service a single public endpoint. The load balancer nodes may advertise to the router according to the Border Gateway Protocol (BGP). Rather than advertising itself, however, a load balancer node may be advertised to the router by one or more neighbor load balancer nodes; the neighbor nodes may terminate the BGP sessions with the router in response to determining that the load balancer node has failed. | 10-16-2014 |
20140310417 | CONNECTION PUBLISHING IN A DISTRIBUTED LOAD BALANCER - A connection publishing method for a distributed load balancer in which a router receives packets from at least one client and routes packet flows to multiple load balancer (LB) nodes, which in turn distribute the packet flows among multiple server nodes. A load balancer (LB) module on each server node determines and publishes a list of active connections between client(s) and the server (a connection publishing packet) back to the LB nodes. The LB module may randomly select a LB node to receive the packet. Upon receiving the packet, the LB node processes the connection information in the packet, distributing the connection information among appropriate LB nodes. Receiving the connection publishing information from the server nodes refreshes leases for the connections on the LB nodes. | 10-16-2014 |
20140310418 | DISTRIBUTED LOAD BALANCER - A distributed load balancer in which a router receives packets from at least one client and routes packet flows to multiple load balancer (LB) nodes according to a per-flow hashed multipath routing technique. For a given packet flow, the LB nodes randomly select a server node as a target for the packet flow from among multiple server nodes and send a connection request to the server node. A load balancer module on the server node makes the decision on whether to accept or reject the connection based on one or more metrics indicating a respective server's current load. If the module accepts the connection request, a connection is established between the server and the client. Otherwise, the load balancer nodes may select another server node and try again. The connections established between clients and servers pass through the load balancer nodes, but are not terminated at the load balancer nodes. | 10-16-2014 |
20160087940 | PRIVATE ALIAS ENDPOINTS FOR ISOLATED VIRTUAL NETWORKS - In accordance with a designation of a private alias endpoint as a routing target for traffic directed to a service from within an isolated virtual network of a provider network, a tunneling intermediary receives a baseline packet generated at a compute instance. The baseline packet indicates a public IP (Internet Protocol) address of the service as the destination, and a private IP address of the compute instance as the source. In accordance with a tunneling protocol, the tunneling intermediary generates an encapsulation packet comprising at least a portion of the baseline packet and a header indicating the isolated virtual network. The encapsulation packet is transmitted to a node of the service. | 03-24-2016 |
Patent application number | Description | Published |
20090023799 | CRYSTALS OF (2-AMINO-4,5,6,7-TETRAHYDROBENZO[b]THIEN-3-YL)(4-CHLOROPHENYL)METHANONE - The present invention provides crystal forms of (2-amino-4,5,6,7-tetrahydrobenzo[b]thiophen-3-yl)(4-chlorophenyl)methanone of the formula | 01-22-2009 |
20130018172 | Metal Abstraction Peptide and Uses Thereof - Compositions comprising certain tripeptides which are capable of binding a metal in a square planar orientation, a square pyramidal orientation, or both, are disclosed in processes for modulating tagged peptides or proteins. Such compositions and processes may be used for site-specific chiral inversion of amino acids, site-specific peptide cleavage, and protein purification, among other uses. | 01-17-2013 |
20130330314 | Metal Abstraction Peptide With Superoxide Dismutase Activity - Compositions comprising peptides that are capable of binding a metal are disclosed. Such compositions can be used for binding metal in a variety of contexts and environments. In various embodiments, peptides are used for antioxidant activity, anti-inflammatory activity, anti-pain therapy, as chemical reagents, and/or as superoxide dismutase mimics. | 12-12-2013 |
20140037626 | Metal Abstraction Peptide With Release of Metal - Compositions comprising peptides that are capable of binding a metal in a square planar orientation, a square pyramidal orientation, or both, are disclosed. Such compositions can be used for binding and releasing a metal in a variety of contexts and environments, such as the treatment of cancer. | 02-06-2014 |
Patent application number | Description | Published |
20080306282 | Novel Forms of [R-(R*,R*)]-2-(4-Fluorophenyl)-Beta,Delta-Dihydroxy-5-(1-Methylethyl)-3-Phenyl-4-[(Phenylamino)Carbonyl]-1H-Pyrrole-1-HeptanoicAcid Calcium Salt (2:1) - Novel forms of [R—(R*,R*)]-2-(4-fluorophenyl)-β,δ-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrole-1-heptanoic acid hemi calcium salt designated Form XX, Form XXI, Form XXII, Form XXIII, Form XXIV, Form XXV, Form XXVI, Form XXVII, Form XXVIII, Form XXIX, and Form XXX, characterized by their X-ray powder diffraction, solid-state NMR, and/or Raman spectroscopy are described, as well as methods for the preparation and pharmaceutical composition of the same, which are useful as agents for treating hyperlipidemia, hypercholesterolemia, osteoporosis, benign prostatic hyperplasia (BPH) and Alzheimer's disease. | 12-11-2008 |
20110301358 | Novel Forms of [R-(R*,R*)]-2-(4-fluorophenyl)-beta,delta-Dihydroxy-5-(1-Methylethyl)-3-P- henyl-4-[(Phenylmino)Carbonyl]-1H-Pyrrole-1-Heptanoic Acid Calcium Salt (2:1) - Novel forms of [R—(R*,R*)]-2-(4-fluorophenyl)-β,δ-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrole-1-heptanoic acid hemi calcium salt designated Form XX, Form XXI, Form XXII, Form XXIII, Form XXIV, Form XXVV, Form XXVI, Form XXVII, Form XXVIII, Form XXIX, and Form XXX, characterized by their X-ray powder diffraction, solid-state NMR, and/or Raman spectroscopy are described, as well as methods for the preparation and pharmaceutical composition of the same, which are useful as agents for treating hyperlipidemia, hypercholesterolemia, osteoporosis, benign prostatic hyperplasia (BPII) and Alzheimer's disease. | 12-08-2011 |
Patent application number | Description | Published |
20160046575 | Novel Forms of [R-(R*,R*)]-2-(4-Fluorophenyl)-Beta, Gamma-Dihydroxy-5-(1-Methylethyl)-3-Phenyl-4-[(Phenylamino)carbonyl]-1H-P- yrrole-1-Heptanoic Acid Calcium Salt (2:1) - Novel forms of [R—(R*,R*)]-2-(4-fluorophenyl)-β,δ-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrole-1-heptanoic acid hemi calcium salt designated Form XX, Form XXI, Form XXII, Form XXIII, Form XXIV, Form XXV, Form XXVI, Form XXVII, Form XXVIII, Form XXIX, and Form XXX, characterized by their X-ray powder diffraction, solid-state NMR, and/or Raman spectroscopy are described, as well as methods for the preparation and pharmaceutical composition of the same, which are useful as agents for treating hyperlipidemia, hypercholesterolemia, osteoporosis, benign prostatic hyperplasia (BPH) and Alzheimer's disease. | 02-18-2016 |
Patent application number | Description | Published |
20140018546 | Novel Forms of [R-(R*,R*)]-2-(4-Fluorophenyl)-Beta, Gamma-Dihydroxy-5-(1-Methylethyl)-3-Phenyl-4-[(Phenylamino)carbonyl]-1H-P- yrrole-1-Heptanoic Acid Calcium Salt (2:1) - Novel forms of [R—(R*,R*)]-2-(4-fluorophenyl)-β,δ-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrole-1-heptanoic acid hemi calcium salt designated Form XX, Form XXI, Form XXII, Form XXIII, Form XXIV, Form XXV, Form XXVI, Form XXVII, Form XXVIII, Form XXIX, and Form XXX, characterized by their X-ray powder diffraction, solid-state NMR, and/or Raman spectroscopy are described, as well as methods for the preparation and pharmaceutical composition of the same, which are useful as agents for treating hyperlipidemia, hypercholesterolemia, osteoporosis, benign prostatic hyperplasia (BPH) and Alzheimer's disease. | 01-16-2014 |
20150045563 | Novel Forms of [R-(R*,R*)]-2-(4-Fluorophenyl)-Beta, Gamma-Dihydroxy-5-(1-Methylethyl)-3-Phenyl-4-[(Phenylamino)carbonyl]-1H-P- yrrole-1-Heptanoic Acid Calcium Salt (2:1) - Novel forms of [R—(R*,R*)]-2-(4-fluorophenyl)-β,δ-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrole-1-heptanoic acid hemi calcium salt designated Form XX, Form XXI, Form XXII, Form XXIII, Form XXIV, Form XXV, Form XXVI, Form XXVII, Form XXVIII, Form XXIX, and Form XXX, characterized by their X-ray powder diffraction, solid-state NMR, and/or Raman spectroscopy are described, as well as methods for the preparation and pharmaceutical composition of the same, which are useful as agents for treating hyperlipidemia, hypercholesterolemia, osteoporosis, benign prostatic hyperplasia (BPH) and Alzheimer's disease. | 02-12-2015 |
Patent application number | Description | Published |
20100221839 | Metal Abstraction Peptide (MAP) Tag and Associated Methods - Compositions comprising a tripeptide having the sequence XC | 09-02-2010 |
20120174712 | Metal Abstraction Peptide (MAP) Tag and Associated Methods - Compositions comprising a tripeptide having the sequence XC | 07-12-2012 |
20120177579 | Metal Abstraction Peptide (MAP) Tag and Associated Methods - Compositions comprising a tripeptide having the sequence XC | 07-12-2012 |
20120177580 | Metal Abstraction Peptide (MAP) Tag and Associated Methods - Compositions comprising a tripeptide having the sequence XC | 07-12-2012 |
20120177667 | Metal Abstraction Peptide (MAP) Tag and Associated Methods - Compositions comprising a tripeptide having the sequence XC | 07-12-2012 |
20120329987 | Metal Abstraction Peptide (MAP) Tag and Associated Methods - Compositions comprising a tripeptide having the sequence XC | 12-27-2012 |
20130018172 | Metal Abstraction Peptide and Uses Thereof - Compositions comprising certain tripeptides which are capable of binding a metal in a square planar orientation, a square pyramidal orientation, or both, are disclosed in processes for modulating tagged peptides or proteins. Such compositions and processes may be used for site-specific chiral inversion of amino acids, site-specific peptide cleavage, and protein purification, among other uses. | 01-17-2013 |
20130330314 | Metal Abstraction Peptide With Superoxide Dismutase Activity - Compositions comprising peptides that are capable of binding a metal are disclosed. Such compositions can be used for binding metal in a variety of contexts and environments. In various embodiments, peptides are used for antioxidant activity, anti-inflammatory activity, anti-pain therapy, as chemical reagents, and/or as superoxide dismutase mimics. | 12-12-2013 |
20140037626 | Metal Abstraction Peptide With Release of Metal - Compositions comprising peptides that are capable of binding a metal in a square planar orientation, a square pyramidal orientation, or both, are disclosed. Such compositions can be used for binding and releasing a metal in a variety of contexts and environments, such as the treatment of cancer. | 02-06-2014 |
20140135484 | Metal Abstraction Peptide (MAP) Tag and Associated Methods - Compositions comprising a tripeptide having the sequence XC | 05-15-2014 |
Patent application number | Description | Published |
20100312280 | ANCHOR-IN-ANCHOR SYSTEM FOR USE IN BONE FIXATION - An anchor-in-anchor fixation system is provided for securing underlying structure, such as bone. The fixation system includes a first bone anchor having a shaft for fixation to underlying bone, and a head that defines an internal bore. A second bone anchor extends through the bore and into underlying bone. A fixation assembly is also provided that includes one or more fixation systems coupled to an auxiliary attachment member configured for long bone fixation, spinal fixation, or fixation of other bones as desired. | 12-09-2010 |
20110028998 | BI-DIRECTIONAL SUTURE PASSER - A bi-directional suture passing instrument configured to approach soft tissues perpendicularly, enables safer and more efficient surgical repairs and minimally invasive techniques to be employed, useful in areas such as annulus repair, meniscal repair, shoulder arthroscopy, hernia repair, laproscopic repair, and wound closure. | 02-03-2011 |
20110045087 | POROUS BIOCOMPATIBLE POLYMER MATERIAL AND METHODS - Embodiments described include devices and methods for forming a porous polymer material. Devices disclosed and formed using the methods described include a spacer for spinal fusion, craniomaxillofacial (CMF) structures, and other structures for tissue implants. | 02-24-2011 |
20110098747 | ARCUATE FIXATION MEMBER - Arcuate fixation members with varying configurations and/or features are provided, along with additional components for use therewith in provided fixation systems and intervertebral implant systems. The arcuate fixation members may be of varying lengths, cross sectional geometries, and/or cross sectional areas, and may be configured with various features such as heads configured to accept other fixation system components, tabs to allow arcuate fixation member-in-arcuate fixation member or fixation anchor-in-arcuate fixation member configurations. Applications of fixation systems and intervertebral implants systems utilizing arcuate fixation members are particularly suitable when a linear line-of-approach for delivering fixation members is undesirable. | 04-28-2011 |
20110106260 | Flexible Vertebral Spacer - A flexible implant system for positioning a flexible spacer between adjacent vertebrae including and interbody spacer and an insertion instrument. The interbody spacer including a central axis, a lateral axis, a top surface positioned generally parallel to the central axis and a plurality of hinge sections extending generally perpendicular to the central axis. A plurality of notches making up the plurality of hinge sections adjacent the top surface that permit the interbody spacer to flex. The interbody spacer further including a groove extending along a lateral side surface, generally parallel to the central axis. An insertion instrument includes a proximal end, a distal end and a tongue extending from the proximal end to the distal end along a non-linear path. The groove slidably engages the tongue to guide the interbody spacer from the proximal end to the distal end along the non-linear path. | 05-05-2011 |
20110160866 | INTERVERTEBRAL IMPLANT WITH BLADES FOR CONNECTING TO ADJACENT VERTEBRAL BODIES - An intervertebral implant ( | 06-30-2011 |
20110166660 | IMPLANT WITH SPIRAL ANCHOR - An intervertebral implant ( | 07-07-2011 |
20130138217 | Intervertebral Implant with Blades for Connecting to Adjacent Vertebral Bodies - An intervertebral implant for insertion into an intervertebral disc space between adjacent vertebral bodies or between two bone portions. The implant includes a spacer portion, a plate portion operatively coupled to the spacer portion and one or more blades for securing the implant to the adjacent vertebral bodies. The blades preferably include superior and inferior cylindrical pins for engaging the adjacent vertebral bodies. The implant may be configured to be inserted via a direct lateral trans-psoas approach. Alternatively, the implant may be configured for insertion via an anterior approach. | 05-30-2013 |
20140012380 | LATERAL INSERTION SPINAL IMPLANT - The present disclosure relates to a spinal implant. The spinal implant may be used for lateral insertion into an intervertebral disc space. For example, the spinal implant may include a spacer body to which a plate is fixed. The intervertebral spacer body may include a pair of opposite sides having a pyramid-shaped teeth to fuse to bone. The plate defines at least one upper and lower borehole that each receives a screw. Each screw attaches the plate to a vertebral body between which the intervertebral spacer body is inserted. The boreholes may include locking threads that are adapted to lock the screws into place by engaging complementary locking threads of head of the screw. | 01-09-2014 |
20140207237 | Porous Biocompatible Polymer Material and Methods - Embodiments described include devices and methods for forming a porous polymer material. Devices disclosed and formed using the methods described a spacer for spinal fusion, craniomaxillofacial (CMF) structures, and other structures for tissue implants. | 07-24-2014 |
20150045895 | Flexible Vertebral Spacer - A flexible implant system for positioning a flexible spacer between adjacent vertebrae including and interbody spacer and an insertion instrument. The interbody spacer including a central axis, a lateral axis, a top surface positioned generally parallel to the central axis and a plurality of hinge sections extending generally perpendicular to the central axis. A plurality of notches making up the plurality of hinge sections adjacent the top surface that permit the interbody spacer to flex. The interbody spacer further including a groove extending along a lateral side surface, generally parallel to the central axis. An insertion instrument includes a proximal end, a distal end and a tongue extending from the proximal end to the distal end along a non-linear path. The groove slidably engages the tongue to guide the interbody spacer from the proximal end to the distal end along the non-linear path. | 02-12-2015 |
20150142055 | ANCHOR-IN-ANCHOR SYSTEM FOR USE IN BONE FIXATION - An anchor-in-anchor fixation system is provided for securing underlying structure, such as bone. The fixation system includes a first bone anchor having a shaft for fixation to underlying bone, and a head that defines an internal bore. A second bone anchor extends through the bore and into underlying bone. A fixation assembly is also provided that includes one or more fixation systems coupled to an auxiliary attachment member configured for long bone fixation, spinal fixation, or fixation of other bones as desired. | 05-21-2015 |
20150272635 | ANCHOR-IN-ANCHOR SYSTEM FOR USE IN BONE FIXATION - An anchor-in-anchor fixation system is provided for securing underlying structure, such as bone. The fixation system includes a first bone anchor having a shaft for fixation to underlying bone, and a head that defines an internal bore. A second bone anchor extends through the bore and into underlying bone. A fixation assembly is also provided that includes one or more fixation systems coupled to an auxiliary attachment member configured for long bone fixation, spinal fixation, or fixation of other bones as desired. | 10-01-2015 |
Patent application number | Description | Published |
20100293113 | METHOD AND SYSTEM FOR TRACKING AND COMPENSATION OF DISTRIBUTORS VIA UNIQUE CODES - A method and system for tracking and providing compensation to distributors of a product by using a unique identification code to identify the product at the point of sale, the original customer, and/or the original distributor. A product and/or advertising materials for the product, bearing a unique product code, are provided to distributors. The customer provides the unique product code at the point of purchase of one or more products. The distributor, who promoted the sale of the products, is identified based on the unique product code. Compensation is provided to the distributor based on the number of products sold. The customer may be offered a discount based on the unique product code at the point of purchase. | 11-18-2010 |
20150023732 | METHODS AND APPARATUS FOR STABILIZATION OF SURFACES - Various embodiments provide surface compositions and methods for repairing durable and/or load-bearing surfaces including roadway voids, manhole structures, and/or safety flooring. Compositions and methods may comprise utilizing a liquid binder, catalyst, and/or primer to provide durable, waterproof, and/or long-lasting surface compositions to dispose within the roadway voids and/or to coat flooring. The surface compositions may cure rapidly through an internal exothermic reaction process to form the repair and/or the safety flooring. In some embodiments, filler materials may be disposed within the liquid binders to provide elasticity, compression, slip resistance, heat transfer, reduced cure time, and/or a desired surface texture to the surface composition. | 01-22-2015 |
Patent application number | Description | Published |
20080251709 | Pmt Gain and Energy Calibrations Using Lutetium Background Radiation - A scintillator ( | 10-16-2008 |
20080265167 | ACHIEVING ACCURATE TIME-OF-FLIGHT CALIBRATIONS WITH A STATIONARY COINCIDENCE POINT SOURCE - A method for calibrating an imaging system includes coincident detecting scatter radiation events from a calibration source located within a bore of the imaging system. The scatter radiation events are subsequently used to compute calibration time offsets for each detector channel in the imaging system. Each detector channel is then calibrated with respective calibration time adjustments. | 10-30-2008 |
20090324042 | METHOD AND SYSTEM FOR IMPROVED TOF PET RECONSTRUCTION - A time of flight positron emission tomography apparatus ( | 12-31-2009 |
20120288177 | MULTI-SECTION ALIGNMENT OF IMAGING DATA - A method of aligning multiple volumetric sections of imaging data is provided. The method comprises aligning a primary volumetric section and a secondary volumetric section which is adjacent to the primary volumetric imaging section, for moving the secondary volumetric section into alignment with the primary volumetric section. A related apparatus for performing the method is also provided. | 11-15-2012 |
20130077827 | AUTOMATED CRYSTAL IDENTIFICATION ACHIEVED VIA MODIFIABLE TEMPLATES - A nuclear imaging system ( | 03-28-2013 |
20130315454 | AUTOMATED CRYSTAL IDENTIFICATION ACHIEVED VIA WATERSHED SEGMENTATION - A nuclear imaging system includes a crystal identification system which receives a flood image which includes a plurality of peaks, each peak responsive to radiation detected by a corresponding scintillator crystal. A crystal identification processor partitions the flood image into a plurality of candidate regions with a watershed segmentator implementing a watershed algorithm. The candidate regions are linked in an adjacency graph, and then classified as background or relevant, where relevant regions contain a peak within the watershed lines. The regions are then assigned to a crystal according to an objective function and an assignability score. A calibration processor maps the peaks to a rectangular grid. | 11-28-2013 |