Patent application number | Description | Published |
20090162911 | STRAIN FOR BUTANOL PRODUCTION - Using screening of transposon random insertion mutants, genes involved in a complex that is a three-component proton motive force-dependent multidrug efflux system were found to be involved in | 06-25-2009 |
20090203097 | STRAIN FOR BUTANOL PRODUCTION - Screening of fatty acid fed bacteria which are not natural butanol producers identified increased membrane cyclopropane fatty acid as providing improved butanol tolerance. Increasing expression of cyclopropane fatty acid synthase in the presence of the enzyme substrate that is either endogenous to the cell or fed to the cell, increased butanol tolerance. Bacterial strains with increased cyclopropane fatty acid synthase and having a butanol biosynthetic pathway are useful for production of butanol. | 08-13-2009 |
20090203139 | PRODUCTION OF FOUR CARBON ALCOHOLS USING IMPROVED STRAIN - Using screening of transposon random insertion mutants, genes involved in accumulation of (p)ppGpp were found to be involved in bacterial cell response to butanol. Reduced production of proteins with enzymatic activity for (p)ppGpp biosynthesis confers increased butanol tolerance. Bacterial strains with reduced (p)ppGpp accumulation and having a butanol or 2-butanone biosynthetic pathway are useful for production of butanol or 2-butanone. | 08-13-2009 |
20090280546 | YEAST STRAIN FOR PRODUCTION OF FOUR CARBON ALCOHOLS - Yeast cells with a reduced general control response to amino acid starvation were found to have increased tolerance to butanol in the growth medium. The reduced response was engineered by genetic modification of a gene involved in the response, a GCN gene, to eliminate activity of the encoded protein. Yeast strains with an engineered butanol biosynthetic pathway and a genetic modification in a gene involved in the general control response to amino acid starvation, which have increased butanol tolerance, are useful for production of butanol. | 11-12-2009 |
20100167363 | YEAST WITH INCREASED BUTANOL TOLERANCE INVOLVING FILAMENTOUS GROWTH RESPONSE - Increasing tolerance to butanol in yeast has been accomplished by increasing activity of the filamentous growth response. Yeast with increased expression of MSS11 | 07-01-2010 |
20100167364 | YEAST WITH INCREASED BUTANOL TOLERANCE INVOLVING CELL WALL INTEGRITY PATHWAY - Increasing tolerance to butanol in yeast has been accomplished by increasing activity of the cell wall integrity pathway. Yeast with increased expression of SLT2p, a mitogen activated protein kinase of the MAPK module of the cell wall integrity pathway had increased tolerance to isobutanol. These yeast may be used for improved butanol production. | 07-01-2010 |
20100167365 | YEAST WITH INCREASED BUTANOL TOLERANCE INVOLVING HIGH OSMOLARITY/GLYCEROL RESPONSE PATHWAY - Increasing tolerance to butanol in yeast has been accomplished by increasing activity of the high osmolarity/glycerol response pathway. Yeast with increased expression of PBS2p, a mitogen activated protein kinase kinase of the MAPK module of the high osmolarity/glycerol response pathway may be used for improved butanol production. | 07-01-2010 |
20130130342 | Yeast Strain for Production of Four Carbon Alcohols - Yeast cells with a reduced general control response to amino acid starvation were found to have increased tolerance to butanol in the growth medium. The reduced response was engineered by genetic modification of a gene involved in the response, a GCN gene, to eliminate activity of the encoded protein. Yeast strains with an engineered butanol biosynthetic pathway and a genetic modification in a gene involved in the general control response to amino acid starvation, which have increased butanol tolerance, are useful for production of butanol. | 05-23-2013 |
20140004526 | Genetic Switches for Butanol Production | 01-02-2014 |