Laporte, US
Brent Laporte, Issaquah, WA US
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20090261141 | ERGONOMIC STAPLER AND METHOD FOR SETTING STAPLES - A stapler having ergonomic benefits includes a housing situated along a principal axis. The housing is conformed to include a handle and a head with a staple discharge opening spaced apart from the handle along the principal axis. A generally planar knife is within the head and oriented in parallel to a plane defined by an intersection of the principal axis and a normal axis. A magazine includes a sole at the staple discharge opening. The sole receives at least one first strip of staples. The first strip of staples is aligned such that the bight of a first staple within the strip of staples is parallel to the principal axis and the first strip is aligned with a lateral axis orthogonal to both of the principal and normal axes. | 10-22-2009 |
Brock Laporte, San Carlos, CA US
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20120243416 | APPARATUS AND METHOD FOR DATA COMMUNICATION IN AN ENERGY DISTRIBUTION NETWORK - A system for communicating information on an energy distribution network is disclosed. In one embodiment, the system includes a local supervisor on a communication network, wherein the local supervisor can collect data from one or more energy generation/monitoring devices. The system also includes a command center on the communication network, wherein the command center can generate one or more commands for controlling the one or more energy generation devices. The local supervisor can periodically transmit a data signal indicative of the data to the command center via a first channel of the communication network at a first interval. The local supervisor can also periodically transmit a request for a command to the command center via a second channel of the communication network at a second interval shorter than the first interval. This channel configuration provides effective data communication without a significant increase in the use of network resources. | 09-27-2012 |
20140258824 | ENHANCED FAVORITES SERVICE FOR WEB BROWSERS AND WEB APPLICATIONS - The invention provides two enhancements for the use of favorites during a Web browsing session. A first enhancement identifies when a user is adding a favorite to his favorites list and auto-suggests a category under which the favorite could be stored. A second enhancement allows a user to review his favorites list and see a summary of feed content (RSS or other standard) on each feed enabled page on his favorites list, without requiring the user to link to the page in question. | 09-11-2014 |
Brock D. Laporte, San Carlos, CA US
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20080209350 | ACTIVE AND PASSIVE PERSONALIZATION TECHNIQUES - A method for personalizing content for a particular user in a computing system comprising a user interface configured to display content. The method comprises identifying a long term profile having one or more features in a feature set and a long term level of importance associated with each term in the feature set, identifying a short term profile having one or more features in the feature set and a short term level of importance associated with each term in the feature set, identifying input related to the display of the one or more content items on the user interface, and using the input to modify the short term level of importance and the long term level of importance associated with each term in the feature set to form a modified user interest set. | 08-28-2008 |
20120089623 | ACTIVE AND PASSIVE PERSONALIZATION TECHNIQUES - A method for personalizing content for a particular user in a computing system comprising a user interface configured to display content. The method comprises identifying a long term profile having one or more features in a feature set and a long term level of importance associated with each term in the feature set, identifying a short term profile having one or more features in the feature set and a short term level of importance associated with each term in the feature set, identifying input related to the display of the one or more content items on the user interface, and using the input to modify the short term level of importance and the long term level of importance associated with each term in the feature set to form a modified user interest set. | 04-12-2012 |
Brock Daniel Laporte, San Carlos, CA US
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20080209340 | PEER-TO-PEER ACCESS OF PERSONALIZED PROFILES USING CONTENT INTERMEDIARY - A method for personalizing content for a particular user in a computing system comprising a user interface configured to display content. The method comprises identifying a content item accessed by a user, identifying features associated with the content item; using the features of the content item to identify one or more third party profiles that substantially match a content profile of the content item, and displaying a list of the identified third party profiles. | 08-28-2008 |
20140108954 | PEER-TO-PEER ACCESS OF PERSONALIZED PROFILES USING CONTENT INTERMEDIARY - A method for personalizing content for a particular user in a computing system comprising a user interface configured to display content. The method comprises identifying a content item accessed by a user, identifying features associated with the content item; using the features of the content item to identify one or more third party profiles that substantially match a content profile of the content item, and displaying a list of the identified third party profiles. | 04-17-2014 |
David A. Laporte, Livonia, MI US
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20080300898 | Document processing services - A document processing device is provided. A device service is configured to generate information concerning a document processed by the document processing device. A client interface is included in the device service and is configured to perform at least one of (a) publishing an event to a plurality of clients based on at least one of a status of the document processing device and the information and (b) providing an instruction to the document processing device based on a message from one of the plurality of clients. One or more application services are in selective communication with the device service and at least one of the clients. | 12-04-2008 |
John-Paul Laporte, Farmington Hills, MI US
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20130234462 | VEHICLE BODY STRUCTURE - A vehicle body structure includes a roof ditch and an elongated molding member that convers the roof ditch. Each of a plurality of fastening members extends upward from a recessed support surface of the roof ditch to a level that is below upper edges of first and second wall surfaces of the roof ditch. The molding member includes a main section and a plurality of attachment structures. The main section and the attachment structures are formed unitarily as a single monolithic element. The main section is located between upper edges of the first and second wall surfaces and laterally conceals the roof ditch. The attachment structures extending from the main section into the roof ditch and including a bottom wall defining an opening fixedly receiving a corresponding one of the fastening members. | 09-12-2013 |
20130234474 | VEHICLE BODY STRUCTURE - A vehicle body structure includes a roof ditch that is defined by a recessed support surface, first and second wall surfaces that extend longitudinally along sides of the recessed support surface. A cover includes a top portion that spans a width of the roof ditch between respective top edges thereof. The cover includes a cover attachment section and a molding attachment section. The cover attachment section couples the cover at a fixed position relative to the vehicle body panel. A molding member extends in a lengthwise direction along the roof ditch between the first and second wall surfaces. The molding member includes an attachment member mating with the molding attachment section of the cover to form a lengthwise movement connection that retains the cover to the molding member with a predetermined amount of movement along the lengthwise direction of the roof ditch. | 09-12-2013 |
Karla Laporte, Redmond, WA US
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20110300080 | ACIDIFIED CHLORITE DISINFECTANT COMPOSITIONS WITH OLEFIN STABILIZERS - A two-part disinfecting systems, as well as disinfecting compositions and methods for making and using the same. The two-part disinfecting system contains a first part and a second part adapted to be mixed to yield an aqueous disinfecting composition, wherein the first part comprises a chlorite and the second part comprises an acid, and wherein the first part, the second part, or both the first and second parts comprise an olefin compound. | 12-08-2011 |
Laurent H. Laporte, Lynnwood, WA US
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20090292505 | Machine vibration baseline synthesizer - Machine vibration baselines are synthesized without averaging historical vibration data. Instead machinery configuration information is used, including data about the machine train, the machine's rotating components, and the machine speeds. For each component being considered, a plurality of parameters is identified for deriving baseline portions. The parameters for one component are used to identify baseline vibration amplitude floor values, vibration amplitudes at frequencies corresponding to various harmonics of a rotational speed, and vibration amplitudes corresponding to forcing frequencies and their harmonics/sidebands. Parameters for other components also may be used to identify amplitudes at harmonic frequencies and forcing frequencies. | 11-26-2009 |
Matthew G. Laporte, Honeybrook, PA US
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20090048183 | IAP BINDING COMPOUNDS - IAP binding molecules and compositions including these are disclosed. The IAP binding molecules interact with IAPs (inhibitor of apoptosis proteins) in cells and may be used to modify apoptosis in cells treated with such molecules. Embodiments of these compounds have a K | 02-19-2009 |
20110003877 | SMAC Mimetic - A SMAC mimetic and pharmaceutical compositions thereof and methods of use. | 01-06-2011 |
20110237517 | IAP INHIBITORS - The present invention describes compounds, processes for their preparation, pharmaceutical compositions containing them, and their use in therapy. | 09-29-2011 |
20110294827 | IAP BINDING COMPOUNDS - IAP binding molecules and compositions including these are disclosed. The IAP binding molecules interact with IAPs (inhibitor of apoptosis proteins) in cells and may be used to modify apoptosis in cells treated with such molecules. Embodiments of these compounds have a K | 12-01-2011 |
20110305777 | DIMERIC IAP ANTAGONISTS - Smac mimetics that inhibit IAPs. | 12-15-2011 |
20120115922 | SMAC MIMETEC - A SMAC mimetic and pharmaceutical compositions thereof and methods of use. | 05-10-2012 |
20120157390 | IAP Inhibitors - Smac mimetics that inhibit IAPs. | 06-21-2012 |
20130012564 | SMAC Mimetic - A SMAC mimetic and pharmaceutical compositions thereof and methods of use. | 01-10-2013 |
20130289075 | IAP BINDING COMPOUNDS - IAP binding molecules and compositions including these are disclosed. The IAP binding molecules interact with IAPB (inhibitor of apoptosis proteins) in cells and may be used to modify apoptosis in cells treated with such molecules. Embodiments of these compounds have a K | 10-31-2013 |
20140073579 | SMAC Mimetic - A SMAC mimetic and pharmaceutical compositions thereof and methods of use. | 03-13-2014 |
Matthew G. Laporte, Honey Brook, PA US
Patent application number | Description | Published |
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20100075911 | DIMERIC IAP INHIBITORS - Molecular mimics of Smac are capable of modulating apoptosis through their interaction with cellular IAPs (inhibitor of apoptosis proteins). The mimetics are based on a monomer or dimer of the N-terminal tetrapeptide of IAP-binding proteins, such as Smac/DIABLO, Hid, Grim and Reaper, which interact with a specific surface groove of IAP. Also disclosed are methods of using these peptidomimetics for therapeutic purposes. In various embodiments of the invention the Smac mimetics of the invention are combined with chemotherapeutic agents, including, but not limited to topoisomerase inhibitors, kinase inhibitors, NSAIDs, taxanes and platinum containing compounds use broader language | 03-25-2010 |
20110301151 | DIMERIC IAP INHIBITORS - Molecular mimics of Smac are capable of modulating apoptosis through their interaction with cellular IAPs (inhibitor of apoptosis proteins). The mimetics are based on a monomer or dimer of the N-terminal tetrapeptide of IAP-binding proteins, such as Smac/DIABLO, Hid, Grim and Reaper, which interact with a specific surface groove of IAP. Also disclosed are methods of using these peptidomimetics for therapeutic purposes. In various embodiments of the invention the Smac mimetics of the invention are combined with chemotherapeutic agents, including, but not limited to topoisomerase inhibitors, kinase inhibitors, NSAIDs, taxanes and platinum containing compounds use broader language | 12-08-2011 |
20130289042 | DIMERIC IAP INHIBITORS - Molecular mimics of Smac are capable of modulating apoptosis through their interaction with cellular IAPs (inhibitor of apoptosis proteins). The mimetics are based on a monomer or dimer of the N-terminal tetrapeptide of IAP-binding proteins, such as Smac/DIABLO, Hid, Grim and Reaper, which interact with a specific surface groove of IAP. Also disclosed are methods of using these peptidomimetics for therapeutic purposes. In various embodiments of the invention the Smac mimetics of the invention are combined with chemotherapeutic agents, including, but not limited to topoisomerase inhibitors, kinase inhibitors, NSAIDs, taxanes and platinum containing compounds use broader language | 10-31-2013 |
20140329823 | Dimeric IAP Inhibitors - Molecular mimics of Smac are capable of modulating apoptosis through their interaction with cellular IAPs (inhibitor of apoptosis proteins). The mimetics are based on a monomer or dimer of the N-terminal tetrapeptide of IAP-binding proteins, such as Smac/DIABLO, Hid, Grim and Reaper, which interact with a specific surface groove of IAP. Also disclosed are methods of using these peptidomimetics for therapeutic purposes. In various embodiments of the invention the Smac mimetics of the invention are combined with chemotherapeutic agents, including, but not limited to topoisomerase inhibitors, kinase inhibitors, NSAIDs, taxanes and platinum containing compounds use broader language | 11-06-2014 |
Matthew G. Laporte, Malvern, PA US
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20110288116 | IAP INHIBITORS - The present invention describes compounds of the following formula: processes for their preparation, pharmaceutical compositions containing them, and their use in therapy. The compounds of the present invention inhibit IAPs (inhibitors of apoptosis proteins) and thus are useful in the treatment of cancer, autoimmune diseases and other disorders where a defect in apoptosis is implicated. | 11-24-2011 |
20120094917 | IAP INHIBITORS - The present invention describes compounds, processes for their preparation, pharmaceutical compositions containing them, and their use in therapy. | 04-19-2012 |
20120135990 | IAP INHIBITORS - The present invention describes compounds, processes for their preparation, pharmaceutical compositions containing them, and their use in therapy. | 05-31-2012 |
20130274278 | IAP INHIBITORS - The present invention describes compounds, processes for their preparation, pharmaceutical compositions containing them, and their use in therapy. | 10-17-2013 |
Regent Laporte, San Diego, CA US
Patent application number | Description | Published |
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20090054309 | Peptidic vasopressin receptor agonists - The present invention relates to novel compounds, pharmaceutical compositions comprising the same, use of said compounds for the manufacture of a medicament for treatment of inter alia shock conditions as well as to a method for treatment of said conditions, wherein said compounds are administered. The compounds are represented by the general formula (I), as further defined in the specification. | 02-26-2009 |
20090305959 | Use of Peptidic Vasopressin Receptor Agonists - The present invention relates to the use of novel compounds for the manufacture of a medicament for treatment of, inter alia, conditions associated with critical care as well as to a method for treatment of said conditions, wherein said compounds are administered. The compounds utilised are represented by the general formula (I), as further defined in the specification. | 12-10-2009 |
20110237494 | USE OF PEPTIDIC VASOPRESSION RECEPTOR AGONISTS - The present invention relates to the use of novel compounds for the manufacture of a medicament for treatment of inter alia conditions associated with critical care as well as to a method for treatment of said conditions, wherein said compounds are administered. The compounds utilised are represented by the general formula (I), as further defined in the specification. | 09-29-2011 |
20120196808 | Peptidic Vasopressin Receptor Agonists - The present application relates to novel compounds, pharmaceutical compositions comprising the same, use of said compounds for the manufacture of a medicament for treatment of inter alia shock conditions as well as to a method for treatment of said conditions, wherein said compounds are administered. The compounds are represented by the general formula (I), as further defined in the specification. | 08-02-2012 |
Richard Laporte, Collierville, TN US
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20090025957 | Extruded wire duct end cap - The present invention provides a wiring duct assembly including a duct base, a cover, and an end cap. The end cap is attached to the open end of the duct base with a friction fit to prevent any objects from accidentally entering the inside of the wiring duct. The cover attaches to the duct base forming an enclosure for holding the wiring therein. The end cap is designed to fit on the inside of the duct base so that the end cap does not interfere and add to the overall size of the wiring duct. | 01-29-2009 |
20090172922 | CABLE TIE HAVING DETACHABLE TAIL - A one-piece cable tie includes a tail which is configured with a plurality of slits or notches therein. These slits are in alignment with the recesses in the tail and extend no deeper than the depth of the recesses. Such slits are designed to aid the use in removing the excess tail from the cable tie once the tie has been tensioned around a bundle. The user first bends the tail so as to close the slits in one side of the tie and then twists the tie about its longitudinal axis so as to separate the excess tail from the tie. | 07-09-2009 |
Richard B. Laporte, Collierville, TN US
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20130098007 | Combination Liquid-Cooled Exhaust Manifold Assembly and Catalytic Converter Assembly For A Marine Engine - An exhaust system for a in e engine comprising liquid-cooled manifold and catalytic converter assemblies. Each assembly uses a separate cooling system to cool either the exhaust manifold or a shell inside which resides the catalytic converter. The housing or shell containing the catalytic converter uses water to cool an exterior surface of a water jacket to an acceptable temperature conforming to federal regulations. The liquid-cooled manifold assembly may use either water or glycol to cool outer cooling tubes surrounding exhaust tubes extending from the engine block to the catalytic converter assembly. | 04-25-2013 |
Robert J. Laporte, Tucson, AZ US
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20130181086 | MITIGATION OF DRIFT EFFECTS IN SECONDARY INERTIAL MEASUREMENTS OF AN ISOLATED DETECTOR ASSEMBLY - The 6-axis position and attitude of an imaging vehicle's detector assembly is measured by mounting the detector assembly on a compliant isolator and separating the main 6-axis IMU on the vehicle from a secondary IMU comprising at least inertial rate sensors for pitch and yaw on the detector assembly. The compliant isolator couples low-frequency rigid body motion of the vehicle below a resonant frequency to the isolated detector assembly while isolating the detector assembly from high-frequency attitude noise above the resonant frequency. A computer processes measurements of the 6-axis rigid body motion and the angular rate of change in yaw and pitch of the isolated detector assembly to mitigate the drift and noise error effects of the secondary inertial rate sensors and estimate the 6-axis position and attitude of the detector assembly. | 07-18-2013 |
Steve R. Laporte, San Antonio, TX US
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20140222101 | DETERMINATION OF SLEEP QUALITY FOR NEUROLOGICAL DISORDERS - A device determines values for one or more metrics that indicate the quality of a patient's sleep based on sensed physiological parameter values. Sleep efficiency, sleep latency, and time spent in deeper sleep states are example sleep quality metrics for which values may be determined. The sleep quality metric values may be used, for example, to evaluate the effectiveness of a therapy delivered to the patient by a medical device. In some embodiments, determined sleep quality metric values are automatically associated with the therapy parameter sets according to which the medical device delivered the therapy when the physiological parameter values were sensed, and used to evaluate the effectiveness of the various therapy parameter sets. The medical device may deliver the therapy to treat a non-respiratory neurological disorder, such as epilepsy, a movement disorder, or a psychological disorder. The therapy may be, for example, deep brain stimulation (DBS) therapy. | 08-07-2014 |
Steve R. Laporte, Arden Hills, MN US
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20120022340 | DETECTING SLEEP TO EVALUATE THERAPY - A system includes one or more sensors and a processor. Each of the sensors generates a signal as a function of at least one physiological parameter of a patient that may discernibly change when the patient is asleep. The processor monitors the physiological parameters, and determines whether the patient is asleep based on the parameters. In some embodiments, the processor determines plurality of sleep metric values, each of which indicates a probability of the patient being asleep, based on each of a plurality of physiological parameters. The processor may average or otherwise combine the plurality of sleep metric values to provide an overall sleep metric value that is compared to a threshold value in order to determine whether the patient is asleep. In addition, an electroencephalogram signal may be used to identify sleep states of the patient. | 01-26-2012 |
Tedd Laporte, Canton, MI US
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20080202472 | Fuel rail support bracket - A fuel rail mounting bracket for use in a fuel charging assembly of a vehicle engine is disclosed. The fuel rail mounting bracket may include a bolt support portion mounted to the vehicle engine; a transition zone extending from the bolt support portion; and a support hoop portion extending from the transition zone and supportably mounted around the fuel rail, the support hoop portion having a main wall thickness and including an upper fracture recess adjacent to the transition zone that has an upper fracture wall thickness that is less than the main wall thickness, and a lower fracture recess, adjacent to the transition zone and spaced from the upper fracture recess, having a lower fracture wall thickness that is less than the main wall thickness. | 08-28-2008 |
Wesley David Laporte, Provo, UT US
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20140264075 | PORTABLE ELECTRONIC DEVICE SANITIZER - A personal electronic device (PED) sanitization device comprises a compartment configured to receive a plurality of PEDs and one or more emitters configured to emit electro-optical (EO) radiation into the interior of the compartment. The compartment may comprise a support member configured to maintain the plurality of PEDs such that substantially an entire surface of each of the plurality of PEDs is exposed to EO radiation emitted by the one or more emitters. | 09-18-2014 |
Zachary Laporte, Franklin, WI US
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20140250695 | UTILITY KNIFE - A utility knife includes a first handle portion and a second handle portion removably coupled to the first handle portion to define a housing. The first handle portion includes a first bore and the second handle portion includes a second bore. The utility knife also includes a blade carrier slidably received within housing and a blade removable coupled to the blade carrier for movement with the blade carrier relative to the housing. The utility knife also includes a double-lead fastener including a head, an unthreaded portion received within the first bore, and a double-lead threaded portion received within the second bore to couple the first handle portion and the second handle portion. | 09-11-2014 |