Patent application number | Description | Published |
20090258795 | Gene expression markers for prediction of patient response to chemotherapy - A method of predicting clinical outcome in a subject diagnosed with cancer and treated with chemotherapy comprising determining evidence of the expression of one or more predictive RNA transcripts or their expression products in a biological sample comprising cancer cells obtained from the subject. | 10-15-2009 |
20090305277 | GENE EXPRESSION MARKERS FOR PREDICTION OF PATIENT RESPONSE TO CHEMOTHERAPY - The present invention relates to gene sets useful in assessing prognosis and/or predicting the response of cancer, e.g. colorectal cancer to chemotherapy. In addition, the invention relates to a clinically validated cancer test, e.g. colorectal test, for assessment of prognosis and/or prediction of patient response to chemotherapy, using expression analysis. The present invention accommodates the use of archived paraffin embedded biopsy material for assay of all markers in the relevant gene sets and therefore is compatible with the most widely available type of biopsy material. | 12-10-2009 |
20100285980 | GENE EXPRESSION PROFILE ALGORITHM AND TEST FOR LIKELIHOOD OF RECURRENCE OF COLORECTAL CANCER AND RESPONSE TO CHEMOTHERAPY - Algorithm-based molecular assays that involve measurement of expression levels of prognostic and/or predictive genes, or co-expressed genes thereof, from a biological sample obtained from a cancer patient, and analysis of the measured expression levels to provide information concerning the likelihood of recurrence of colorectal cancer and/or the likelihood of a beneficial response to chemotherapy for the patient are provided herein. Methods of analysis of gene expression values of prognostic and/or predictive genes, as well as methods of identifying gene expression-tumor region ratios, tumor-associated stromal surface area, and gene cliques, i.e. genes that co-express with a validated biomarker and thus may be substituted for that biomarker in an assay, are also provided. | 11-11-2010 |
20120040842 | Gene Expression Markers for Prediction of Patient Response to Chemotherapy - The present invention relates to gene sets useful in assessing prognosis and/or predicting the response of cancer, e.g. colorectal cancer to chemotherapy. In addition, the invention relates to a clinically validated cancer test, e.g. colorectal test, for assessment of prognosis and/or prediction of patient response to chemotherapy, using expression analysis. The present invention accommodates the use of archived paraffin embedded biopsy material for assay of all markers in the relevant gene sets and therefore is compatible with the most widely available type of biopsy material. | 02-16-2012 |
Patent application number | Description | Published |
20120063050 | METHODS FOR FORMING A STRUCTURE HAVING A LIGHTNING STRIKE PROTECTION - A method for forming a structure having lightning strike protection includes receiving at least one structural layer, receiving at least one lightning strike protection strip disposed on at least one reinforcement layer, automatically applying the at least one lightning strike protection strip disposed on the at least one reinforcement layer onto the at least one structural layer, and forming the at least one structural layer, the at least one lightning strike protection strip, and the at least one reinforcement layer, into the structure. The at least one lightning strike protection strip comprises a first material, and the at least one reinforcement layer comprises a second material different from the first material. The automatically applying may include using at least one of fiber placement equipment, tape laying equipment, and similar automated equipment. | 03-15-2012 |
20130000838 | FLUID MEDIUM NON-CONTACT CONSOLIDATION - A pressure head for use in a fiber placement system for thermoplastic composite materials is disclosed. Plies of thermoplastic composite tape are placed onto a mandrel to form a shaped object. The pressure head includes a nozzle and at least one delivery tube for providing fluid medium mixture to the nozzle body, wherein the nozzle directs the fluid medium onto a surface of the shaped object thereby providing a pressure on the surface without direct physical contact of the nozzle with the plies of thermoplastic composite tape. | 01-03-2013 |
20130164498 | THERMOPLASTIC COMPOSITE PREPREG FOR AUTOMATED FIBER PLACEMENT - An improved thermoplastic composite prepreg tape is disclosed. The prepreg tape is optimized for high-speed, high quality in-situ consolidation during automated fiber placement. Embodiments of the prepreg tape have uniform dimensions (cross section, width, and thickness), uniform energy absorption, uniform surface roughness, and sufficient resin at the surface to affect a bond between layers. | 06-27-2013 |
20130180194 | ULTRA LIGHT FIBER PLACED TRUSS - A novel composite beam is disclosed. The composite beam may comprise variations in the surface that can be used to create open and closed surfaces for the modulation of natural light. The composite beam may also be optimized for the applied loads by placing the fibers in the direction of the applied loads and/or increasing the fiber density in the regions of higher loads. | 07-18-2013 |