Ladine
James R. Ladine, Uxbridge, MA US
Patent application number | Description | Published |
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20110046910 | Method and System for Sample Testing - The invention provides a system and method for testing samples and, in one embodiment, a system for directing and coordinating the operations of hardware components and performance of tasks of laboratory personnel. The system includes a user interface for receiving requests from one or more users. Each request comprises a list of one or more samples to be tested and specifies one or more tests to be conducted on each sample. The system also includes a sample preparation station for maintaining a library of all received samples and creating a sublibrary of samples based on the test(s) to be conducted. The system directs hardware components and laboratory personnel (collectively, laboratory resources) to conduct the requested tests and reports test results to the user(s) who have requested the test(s). | 02-24-2011 |
James R. Ladine, Whitinsville, MA US
Patent application number | Description | Published |
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20100173359 | ENHANCED BIOTHERAPEUTIC PRODUCTION USING INHIBITORY RNA - Compositions, kits, systems, equipment, and protocols utilize synthetic siRNA having a delivery facilitating moiety in improved bioprocesses that enhance the production of biomaterials. The siRNA can target genes associated with the following: 1) deleterious vector derived genes; 2) genes that confer non-optimal growth or differentiation properties to the cells; 3) genes that can influence heterogeneity or post-translational modification pattern of the desirable gene product; 4) genes that highly express non-desired proteins; 5) genes that express proteins which interfere with purification of the desired protein; and 6) other genes that can interfere with the bioprocess. | 07-08-2010 |
James Robert Ladine, Uxbridge, MA US
Patent application number | Description | Published |
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20090247417 | METHOD AND SYSTEM FOR DRUG SCREENING - The invention provides a system and method for screening drugs from candidate compounds selected from a library. The system includes multiple hardware components and a computer software system for scheduling and coordinating the operations of the hardware components. A user of the system requests a series of assays to be performed on the candidate compounds. Each assay is associated with a test acceptance criteria. Interdependencies of these assays may be specified. The software system schedules the hardware components to run each assay with minimum hardware idle time possible based on the assays requested and the interdependencies of these assays specified. The software system coordinates and directs the flow of samples and data through the system. A decision whether a sample can proceed to the next assay as scheduled may be made automatically based on test acceptance criteria, or manually modified by the user. All assays can be performed in an automated fashion once the samples are provided to the system. | 10-01-2009 |