Lader
Alan Lader, Stoughton, MA US
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20100292313 | COMPOSITIONS AND METHODS FOR TREATING ISCHEMIA AND ISCHEMIA-REPERFUSION INJURY - The present invention relates to compositions comprising a substantially pure compound represented by Structural Formula II: | 11-18-2010 |
20110160294 | COMPOSITIONS AND METHODS FOR TREATING ISCHEMIA AND ISCHEMIA-REPERFUSION INJURY - The present invention relates to compositions comprising a substantially pure compound represented by Structural Formula I: | 06-30-2011 |
Alan S. Lader, Stoughton, MA US
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20120135932 | Compositions And Methods For Treating Ischemia And Ischemia-Reperfusion Injury - The present invention relates, in some embodiments, to compositions comprising a substantially pure compound represented by Structural Formula (I) and methods of using such compounds to activate cytoprotective kinases. In additional embodiments, the invention relates to methods for treating an ischemia or an ischemia-reperfusion injury in a subject, comprising administering to the subject an effective amount of a compound of the invention (e.g., in multiple doses). The values and preferred values of the variables in Structural Formula (I) are defined herein. | 05-31-2012 |
20130237483 | Lipoyl Compounds And Their Use for Treating Ischemic Injury - The present invention relates, in various embodiments, to a compound represented by Structural Formula (I), pharmaceutically acceptable salts or prodrugs thereof, and compositions comprising said compounds, or pharmaceutically acceptable salts or prodrugs thereof. Methods of using compounds of Structural Formulas (I) and (la) or compositions comprising compounds of Structural Formulas (I) and (la), or pharmaceutically acceptable salts or prodrugs thereof, to treat ischemia or ischemia-reperfusion injury are also disclosed. | 09-12-2013 |
20140274917 | Compositions and Methods for Treating Ischemia and Ischemia-Reperfusion Injury - The present invention relates to compositions comprising a substantially pure compound represented by Structural Formula I: | 09-18-2014 |
20150065564 | LIPOYL COMPOUNDS AND METHODS FOR TREATING ISCHEMIC INJURY - The present invention relates, in various embodiments, to a compound represented by Structural Formula (I), pharmaceutically acceptable salts or prodrugs thereof, and compositions comprising said compounds, or pharmaceutically acceptable salts or prodrugs thereof. Methods of using compounds of Structural Formulas (I) and (Ia) or compositions comprising compounds of Structural Formulas (I) and (Ia), or pharmaceutically acceptable salts or prodrugs thereof, to treat ischemia or ischemia-reperfusion injury are also disclosed. | 03-05-2015 |
Eric Lader, Boyds, MD US
Patent application number | Description | Published |
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20100285484 | APOPTOSIS INDUCING POSITIVE CONTROL FOR EXPRESSION MODULATION EXPERIMENTS - The invention pertains to a method for performing an expression modulating analysis or assay, wherein an apoptosis inducing expression modulating compound targeting a repetitive element present in the untranslated region, in particular the 3′ UTRs of protein coding gene transcripts is introduced into cells to induce apoptosis in the cells as a positive control. Also provided are suitable kits and compositions. | 11-11-2010 |
20140295411 | METHODS AND REAGENTS FOR PRESERVING RNA IN CELL AND TISSUE SAMPLES - This specification relates to the field of molecular biology and provides novel methods and reagents for preserving and protecting the ribonucleic acid (RNA) content of samples from degradation prior to RNA isolation. This preservation may be accomplished without ultra-low temperature storage or disruption of the tissue. | 10-02-2014 |
Eric Fat Lader, Boyds, MD US
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20120142011 | Modified siNA - The present invention pertains to the use of at least one abasic modification within the first 8 nucleotide positions of the 5′ region of the antisense strand of a small interfering nucleic acid (siNA) molecule for reducing off-target effects. Provided are suitable modified siNAs, compositions and methods for producing respective siNAs, as well as kits comprising respective siNAs. | 06-07-2012 |
Eric S. Lader, Boyds, MD US
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20100028852 | METHODS AND REAGENTS FOR PRESERVING RNA IN CELL AND TISSUE SAMPLES - This specification relates to the field of molecular biology and provides novel methods and reagents for preserving and protecting the ribonucleic acid (RNA) content of samples from degradation prior to RNA isolation. This preservation may be accomplished without ultra-low temperature storage or disruption of the tissue. | 02-04-2010 |
20120270316 | METHODS AND REAGENTS FOR PRESERVING RNA IN CELL AND TISSUE S AMPLES - This specification relates to the field of molecular biology and provides novel methods and reagents for preserving and protecting the ribonucleic acid (RNA) content of samples from degradation prior to RNA isolation. This preservation may be accomplished without ultra-low temperature storage or disruption of the tissue. | 10-25-2012 |
Reinhold Lader, Altenmunster DE
Patent application number | Description | Published |
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20120006769 | CROCKERY BASKET AND CROCKERY BASKET SYSTEM - A crockery basket of a dishwasher to accommodate items to be washed includes a basket base piece having at least one open lateral edge area, and at least one separate end piece which is connected to the basket base piece to close the lateral edge area and thereby bound a base area. The end piece can be configured to form a part-surface of the base area or to form no part-surface of the base area. | 01-12-2012 |