Lacko
Andras G. Lacko, Fort Worth, TX US
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20090110739 | Targeted cancer chemotherapy using synthetic nanoparticles - Compositions and methods for delivery of a pharmaceutical to an individual. Delivery vehicles are provided in a formulation of a pharmaceutical that is encapsulated in a synthetic self assembled nanoparticle that includes a lipid binding protein and a lipid monolayer. The interior of the particle represents a hydrophobic core region where lipophilic highly-water insoluble drug molecules may be incorporated. In contrast to liposomes, that include an aqueous interior core surrounded by phospholipid bilayer, the drug carrier nanoparticle described here is composed of a monolayer and a hydrophobic interior. | 04-30-2009 |
20140045950 | DRUG DELIVERY VEHICLE - The invention provide herein provides for a targeted drug delivery vehicle compositions, methods of manufacture, and methods of treatment for therapeutic applications. | 02-13-2014 |
20150343069 | DRUG DELIVERY VEHICLE - The invention provide herein provides for a targeted drug delivery vehicle compositions, methods of manufacture, and methods of treatment for therapeutic applications. | 12-03-2015 |
Andras G. Lacko, Ft. Worth, TX US
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20110312899 | HDL Particles for Delivery of Nucleic Acids - Disclosed are high density lipoprotein-nucleic acid particles, wherein the particles include (a) an apolipoprotein; (b) a nucleic acid component comprising a therapeutic nucleic acid segment; and (c) a polypeptide comprising a positively charged region, wherein the positively-charged region of the polypeptide associates with the nucleic acid component. Also disclosed are pharmaceutical compositions that include a) an apolipoprotein; (b) a nucleic acid component comprising a therapeutic nucleic acid segment; and (c) a polypeptide comprising a positively charged region. Methods that concern the particles and pharmaceutical compositions of the present invention are also set forth, as well as kits. | 12-22-2011 |
Anthony Lacko, San Diego, CA US
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20150056070 | MULTI SURFACE BLOCKER DOOR SYSTEM AND APPARATUS - A multi-surface blocker door system for a thrust reverser of an aircraft is provided. The system may comprise one or more first blocker doors coupled to the inner fixed structure. The first blocker doors may be configured to obstruct a fan duct area adjacent the engine. The system may also comprise one or more second blocker doors coupled to a translating sleeve. The second blocker doors may be configured to obstruct a fan duct area adjacent to an inlet of the nacelle. | 02-26-2015 |
20150136875 | SYSTEM AND METHOD FOR MOUNTING OF THRUST REVERSER TO PYLON - A propulsion system of an aircraft is described herein. In this system, the inner fixed structure (IFS) and the outer sleeve may be separately coupled to the pylon. For instance, the inner fixed structure and the outer sleeve may be hinged separately and attached to different locations of the pylon. Thus, portions of the pylon are exposed to the fan duct air flow path. | 05-21-2015 |
20150143796 | SYSTEM AND METHOD FOR CAPTURED INNER FIXED STRUCTURE - A propulsion system of an aircraft includes an inner fixed structure (IFS) and the outer sleeve that may be separately coupled to the pylon. For instance, the inner fixed structure and the outer sleeve may move independently with respect to each other. A single latch of the latching system disclosed herein, may be configured to latch all 4 panels, (e.g. both halves of the IFS and both doors of the outer sleeve) together and/or in a closed and retained position. | 05-28-2015 |
Ivan Lacko, Cana SK
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20130218374 | DISPLAY SYSTEM AND METHOD FOR GENERATING A DISPLAY - A flight display system and method for generating a flight display. A method for generating a flight display includes determining a position of an aircraft with reference to an airport, calculating a distance required for the aircraft to decelerate and descend for entering a final approach gate of the airport in a stabilized configuration, comparing the position of the aircraft with the distance required for the aircraft to decelerate and descend, and generating a flight display comprising an advisory based on a result of the comparing. A flight display system includes a database, an electronic display device, and a computer processor. The database and the electronic display device are in operable communication with the computer processor for displaying the flight display on the electronic display device. | 08-22-2013 |
20150081138 | AIRCRAFT SYSTEMS AND METHODS FOR DETECTING NON-COMPLIANT PILOT ACTION - Aircraft systems and methods for detecting non-compliant pilot action are provided. The method comprises analyzing an outbound communication from an aircraft to recognize a word or phrase corresponding to a parameter associated with a prior request for pilot action. If the word or phrase is recognized, the method further comprises storing data corresponding to the outbound communication in a data storage device. The stored data and pilot action taken are compared to determine if there is a discrepancy between the pilot action and the stored data. A discrepancy alert is outputted if the discrepancy is determined to exist. A predetermined time interval is timed from the outbound communication. A timeout alert is outputted at a timeout of the predetermined time interval unless the requested pilot action is taken within the predetermined time interval. | 03-19-2015 |
Mark Lacko, Garrison, NY US
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20080202957 | Paperboard CD or DVD tray with paper hub - A CD or DVD tray made from paperboard is provided. The tray may be made from 100% recycled paperboard and can be 100% recyclable. The design of the tray or holder (used interchangeably throughout) uses the structural geometry of facets, central hole and radial slits to form a hub that achieves the function of securing the CD to the tray. Non-structural paper stock is formed into an effective fastening device whereby the fit of the hub is determined by the geometry of the folded paper. The paper tray of the present invention duplicates the functionality of plastic trays and is compatible with industry auto-loading, while providing the environmental benefits of paper. | 08-28-2008 |
Michal Lacko, Puchov SK
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20160129731 | PNEUMATIC VEHICLE TIRE - A pneumatic vehicle tire for commercial vehicles includes a belt having five belt plies having respective sets of reinforcements. The five plies are identified as first, second, third, fourth and fifth plies. The third ply is a 0° ply and the second and fourth belt are working belt plies. The sets of reinforcements of the first and second plies lying adjacent one side of the 0° ply run upward at respective positive slopes and the sets of reinforcements of the fourth and fifth plies lying adjacent the other side of the 0° ply run upward at respective negative slopes. The reinforcements of the fifth ply and the peripheral direction (A-A) of the tire conjointly define an angle φ between 35°≦φ≦70°. The reinforcements in the second and fourth plies having an elongation of ≧0.2% at 10% breaking load. The elongation is measured using reinforcements taken from a fully vulcanized tire. | 05-12-2016 |
Miroslav Lacko, Prievidza SK
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20150082540 | BLANKET AND BLANKET COVER - Blanket with protective effect against cold of dorsal parts of human body during sleep, with composition of two textile layers ( | 03-26-2015 |
Robert A. Lacko, Oxford, CT US
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20120199292 | PLY LOCKING FOR HONEYCOMB PANELS - A tool for forming a panel including a core area, at which plies sandwich a core, and a trim area surrounding the core, at which the plies are bonded together, is provided and includes a body having a surface on which the panel is formable, the surface including core and trim portions for respective correspondence with locations of the core and trim areas of the panel, a border between the core and trim portions defining a surface feature displaced from a plane of the core portion, a lock disposable proximate to the surface feature to increase a pre-bonding friction between the plies at the surface feature and an assembly to apply bonding pressure to the plies and the lock at least at the core and trim areas. | 08-09-2012 |
20120204741 | CO-CURING REUSABLE ELASTOMERIC CAUL PLATE - A caul plate system for a laminate structure includes a plurality of layers of curable caul plies disposed over a laminate structure and substantially conforming to a surface of the laminate structure. A resin is applied to the plurality of layers of caul plies. Co-curing of the plurality of layers of caul plies with the laminate structure hardens the plurality of layers of caul plies such that a normal pressure is applied to the laminate structure during cure of the laminate structure. | 08-16-2012 |
20120255676 | EXTERNAL TO BAGGING MECHANICAL CLAMP - A tool for forming a panel including a core area, at which plies sandwich a core, and a trim area surrounding the core, at which the plies are bonded together, is provided and includes a body having a surface on which the panel is formable, an assembly to apply bonding pressure to the plies at least at the core and trim areas and a clamping device external to the assembly to apply a clamping force to the vacuum bag and the plies. | 10-11-2012 |
20130062808 | CONFORMAL DELTOID NOODLE FOR A COMPOSITE STRUCTURE - A method of fabricating a conformal deltoid noodle includes providing a composite prepreg material having a predetermined length and a width, the predetermined length being aligned along a longitudinal axis; subjecting the composite prepreg material to a cutting process to form a notched section coextensive along the predetermined length; and rolling the composite prepreg material along its width to create the conformal deltoid noodle. | 03-14-2013 |
20150093541 | COMPOSITE STAPLE - A laminate design is provided and includes a substrate formed to define through-holes, an initially uncured pre-preg laminate disposed proximate to the substrate and an initially uncured pre-preg staple. The staple includes a main member and legs extending from the main member and being disposable with the legs extending through the through-holes to pierce the laminate. The staple is co-curable with the laminate. | 04-02-2015 |
20150133016 | IMPACT RESISTANT COMPOSITE PANEL AND METHOD OF FORMING A COMPOSITE PANEL - A composite panel includes a support layer including a first plurality of prepreg plies wrapped around at least one mandrel; a mid-plane impact layer including a second plurality of prepreg plies, the mid-plane impact layer adjacent to the support layer; a upper skin layer including a third plurality of prepreg plies, the upper skin layer adjacent to the mid-place impact layer; and a lower skin layer including a fourth plurality of prepreg plies, the lower skin layer adjacent to the support layer; whereby each of the first, second, third, and fourth plurality of prepreg plies are co-cured to form the composite panel. | 05-14-2015 |