| Patent application number | Description | Published |
|---|
| 20090062339 | COMPOSITIONS AND METHODS FOR SELECTIVE INHIBITION OF NICOTINE ACETYLCHOLINE RECEPTORS - The present invention concerns methods for treating or preventing neurological disorders characterized by dysfunction of nicotinic acetylcholine receptors by administering 2,2,6,6-tetramethylpiperidin-4-yl heptanoate (TMPH), or a pharmaceutically acceptable salt thereof, to the patient. In another aspect, the present invention pertains to pharmaceutical compositions containing TMPH, or a pharmaceutically acceptable salt thereof, and a pharmaceutically acceptable carrier. In another aspect, the present invention pertains to methods for selectively inhibiting nicotinic acetylcholine receptors that lack an α5, α6, or β3 subunit by contacting an effective amount of TMPH, or a pharmaceutically acceptable salt thereof, to the receptor. The method for selectively inhibiting nicotinic acethylcholine receptors that lack an α5 subunit can be carried out in vivo or in vitro. | 03-05-2009 |
| 20090325979 | NOVEL IMIDAZOLYLALKYLCARBONYL DERIVATIVES AS CALCIUM CHANNEL MODULATORS AND PREPARATION METHOD THEREOF - Disclosed are novel imidazolylalkylcarbonyl derivatives useful as calcium channel modulators and a preparation method of the same. Also disclosed is a method for the treatment of diseases by administering the above compounds based on their inhibitory activity against calcium channel. | 12-31-2009 |
| 20100004286 | NOVEL ISOINDOLINONE DERIVATIVES HAVING INHIBITORY ACTIVITY AGAINST T-TYPE CALCIUM CHANNEL AND METHOD FOR PREPARATION THEREOF - Disclosed are isoindolinone derivatives, represented by Chemical Formula 1, having inhibitory activity against T-type calcium channels, pharmaceutically acceptable salts thereof, a preparation method thereof, and a pharmaceutical composition comprising the same as an active ingredient. | 01-07-2010 |
| 20100056545 | NOVEL PHENYLACETATE DERIVATIVES OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF, PREPARATION METHOD THEREOF AND COMPOSITION FOR PREVENTION OR TREATMENT OF DISEASES INDUCED BY ACTIVATION OF T-TYPE CALCIUM ION CHANNEL CONTAINING THE SAME AS AN ACTIVE INGREDIENT - Disclosed herein are a new phenylacetate derivative represented by Chemical Formula 1 or pharmaceutically acceptable salt thereof, a preparation method thereof, and a composition for prevention or treatment of diseases induced by the activation of T-type calcium ion channels containing the same. The composition containing the phenylacetate derivative according to the present invention effectively inhibits the activation of T-type calcium ion channels and may be useful in the prevention or treatment of diseases such as hypertension, cancer, epilepsy, and neurogenic pains induced by the activation of T-type calcium ion channels. | 03-04-2010 |
| 20100094006 | NOVEL PYRAZOLYLMETHYLAMINE COMPOUNDS AS CALCIUM CHANNEL MODULATORS AND PREPARATION METHOD THEREOF - The present invention relates to pyrazolylmethylamine-piperazine derivatives and their pharmaceutically acceptable salts effective as calcium channel modulators and a method of manufacturing the same. The present invention also relates to the medicinal use of the above compounds as therapeutic treatment of diseases due to their effect as calcium channel modulators. | 04-15-2010 |
| 20110319619 | NOVEL 1,6-DISUBSTITUTED-3-AMINO-4,5,6,7-TETRAHYDRO-1H-PYRAZOLO[3,4-C]PYRID- IN-7-ONE COMPOUNDS AND PREPARATION THEREOF - Provided are a novel 1,6-disubstituted-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridin-7-one compound, a pharmaceutically acceptable salt compound thereof, a method for preparing the compound, and an anticancer pharmaceutical composition including the compound as an effective ingredient. | 12-29-2011 |
| 20120329783 | COMPOSITIONS AND METHODS FOR SELECTIVE INHIBITION OF NICOTINE ACETYLCHOLINE RECEPTORS - The present invention concerns methods for treating or preventing neurological disorders characterized by dysfunction of nicotinic acetylcholine receptors by administering 2,2,6,6-tetramethylpiperidin-4-yl heptanoate (TMPH), or a pharmaceutically acceptable salt thereof, to the patient. In another aspect, the present invention pertains to pharmaceutical compositions containing TMPH, or a pharmaceutically acceptable salt thereof, and a pharmaceutically acceptable carrier. In another aspect, the present invention pertains to methods for selectively inhibiting nicotinic acetylcholine receptors that lack an α5, α6, or β3 subunit by contacting an effective amount of TMPH, or a pharmaceutically acceptable salt thereof, to the receptor. The method for selectively inhibiting nicotinic acethylcholine receptors that lack an α5 subunit can be carried out in vivo or in vitro. | 12-27-2012 |
| Patent application number | Description | Published |
|---|
| 20110114596 | BOTTLE - Disclosed herein is a bottle having a neck portion and a body portion for containing liquid contents therein. The body portion includes a plurality of guides which are formed around at least a partial area or an entire area of the body portion in a spiral pattern. The guides protrude inwards from the inner surface of the body portion to have convex shapes, so that the liquid contents are guided towards an opening of the neck portion while spirally revolving inside the body portion, and the body portion is able to be compressed by compression force with respect to a longitudinal direction. A cross-section of each of the plurality of guides has an angled shape of “>” or “<”, and an outermost midpoint (c) of a horizontal medial line of the guide has a round shape, a pointed shape or a vertically angled shape. An upper bent point (a) is formed in an upper portion extending upwards from the outermost midpoint (c) of each of the guides, and a lower bent point (c) is formed in a lower portion extending downwards from the outermost midpoint (c), so that an upright strength of the body portion is maintained even when the liquid contents contained in the body portion move. | 05-19-2011 |
| 20120274043 | APPARATUS FOR ADJUSTING THE HEIGHT OF A SADDLE FOR A BICYCLE - Disclosed herein is an apparatus for adjusting the height of a saddle for a bicycle. The apparatus includes a saddle lift device that moves the saddle upwards or downwards to adjust the height of the saddle, and a controller that controls the operation of the saddle lift device. In the present invention, even when a bicycle is traveling, the height of the saddle can be automatically adjusted to an appropriate height depending on the travel conditions, thus enhancing the safety of a rider and providing convenience. Moreover, the present invention stores information about the body type of the rider and automatically adjusts the height of the saddle to a height suitable for the body type, thus making it markedly easy to adjust the height of the saddle, and enhancing the safety of the rider while riding the bicycle. | 11-01-2012 |
| 20120283057 | AUTOMATIC TRANSMISSION FOR A BICYCLE - The present invention relates to an automatic transmission for a bicycle, including: a front sprocket unit coupled to pedals; a rear sprocket unit mounted to a rear wheel; and a drive chain, extremities of which are wound around one sprocket of the front sprocket unit and around one sprocket of the rear sprocket unit, respectively, whereby the torque and speed of the bicycle can be changed in accordance with the combination of the diameters of the sprockets. The front sprocket unit receives a rotating force, and rotates in a direction that propels a bicycle body having pedals forward, but does not receive a rotating force in a direction opposite the rotating direction. The automatic transmission of the present invention can automatically perform a gear-shifting operation without forcing a rider to work the pedals while riding, yet changing the torque and speed of the bicycle. | 11-08-2012 |
| Patent application number | Description | Published |
|---|
| 20110057541 | HIGH POWER ULTRASONIC TRANSDUCER - A high power ultrasonic transducer includes a first ultrasonic transducer cell and at least one second ultrasonic transducer cell disposed on the first ultrasonic transducer cell. The at least one second ultrasonic transducer cell oscillates together with the first ultrasonic transducer cell. | 03-10-2011 |
| 20120112602 | ULTRASONIC TRANSDUCER CELL AND ULTRASONIC TRANSDUCER CHANNEL AND ULTRASONIC TRANSDUCER INCLUDING THE ULTRASONIC TRANSDUCER CHANNEL - An ultrasonic transducer cell, an ultrasonic transducer channel, and an ultrasonic transducer including the ultrasonic transducer channel are provided. The ultrasonic transducer cell includes a substrate, at least three columns arranged on the substrate at regular intervals, and a thin film arranged on the at least three columns. | 05-10-2012 |
| 20120179043 | SUBJECT DIAGNOSIS SYSTEM, MEDICAL IMAGE SYSTEM FOR PROVIDING DIAGNOSIS IMAGE OF SUBJECT, AND METHOD OF DISPLAYING DIAGNOSIS IMAGE OF SUBJECT - A diagnosis system, a medical image system, and a method of displaying a diagnosis image are provided. The diagnosis system includes a probe including a plurality of sub-arrays, each of the sub-arrays including at least one line of array transducers, the array transducers being configured to transmit and receive signals to and from a subject being diagnosed, and a hybrid beamformer configured to perform analog beamforming in a direction in which the sub-arrays are arranged, and perform digital beamforming in a direction perpendicular to the direction in which the sub-arrays are arranged. | 07-12-2012 |
| 20120277590 | BEAMFORMING METHOD AND APPARATUS, AND MEDICAL IMAGING SYSTEM - A beamforming method includes generating a control signal for implementing a delay time for each of a plurality of transducers of each of a plurality of two-dimensional (2D) transducer-arrays, transmitting the control signal to a plurality of driving units respectively corresponding to the plurality of 2D transducer-arrays via an interposer that electrically connects the plurality of 2D transducer-arrays to each other, and driving each 2D transducer-array of the plurality of 2D transducer-arrays with a corresponding driving unit of the plurality of driving units according to the control signal transmitted via the interposer. | 11-01-2012 |
| 20120316437 | APPARATUS FOR DRIVING TWO-DIMENSIONAL TRANSDUCER ARRAY, MEDICAL IMAGING SYSTEM, AND METHOD OF DRIVING TWO-DIMENSIONAL TRANSDUCER ARRAY - An apparatus for driving a two-dimensional transducer array, a medical imaging system and a method of driving a two-dimensional transducer array are provided. An apparatus for driving a two-dimensional (2D) transducer array including one or more transducers includes one or more drivers configured to respectively drive the transducers, each of the drivers including a register, a comparator, a pulse frequency setter, a multi-pulse controller, a transmission signal generator, a signal transceiver, a transmission and reception switch, and a reception signal amplifier, and a driving controller configured to control the drivers. | 12-13-2012 |
