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Kydonieus

Agis Kydonieus, Kendall Park, NJ US

Patent application numberDescriptionPublished
20090214634COMPOSITIONS AND METHODS FOR THE TREATMENT OF BLADDER CANCER - Compositions and methods for the treatment of bladder cancer include intravesical dosage forms of a neoplastic agent and a permeation enhancer. The neoplastic agent may be valrubicin. Pharmaceutical compositions include intravesical dosage forms of a neoplastic agent complexed liposomes. Tight junction openers may be used for the effective delivery of the neoplastic agent.08-27-2009
20100178323Dermal Delivery Device - A transdermal drug delivery device is disclosed. Over an extended wear period, the device causes cumulative moderate irritation plus significant irritation of less than 5% and/or achieves a meaningful degree of detachment over a seven day period of less than 20%.07-15-2010
20110046599Multi-Day Delivery Of Biologically Active Substances - Compositions and methods for modifying biologically active substances to achieve multi-day delivery of such substances, particularly through oral or parenteral administration, are disclosed. The compositions include the biologically active substance conjugated to a carrier having a suitably long half life, typically more than one day, wherein the conjugate optionally contains a spacer linking the carrier to the biologically active substance. Pharmaceutical formulations of the conjugates are also disclosed, as are methods of extending delivery of a single dose of a biologically active substance for more than one day.02-24-2011

Patent applications by Agis Kydonieus, Kendall Park, NJ US

Agis Kydonieus, Princeton, NJ US

Patent application numberDescriptionPublished
20100255072DERMAL DELIVERY DEVICE WITH IN SITU SEAL - This invention relates to a transdermal drug delivery device that comprises an active ingredient (Al) layer, having a skin contacting surface and a non-skin contacting surface and comprising a volatile component, a release liner impermeable to the volatile component adjacent the skin contacting surface of the Al layer having a peπmeter that extends beyond the perimeter of the Al layer in all directions, and an overlay comprising a pressure sensitive adhesive (PSA) that does not absorb the volatile component adjacent the non-skin contacting surface of the Al layer having a peπmeter of which extends beyond the penmeter of the Al layer in all directions, wherein the release liner and the PSA of the overlay are in contact with and adhered to each other around the peπmeter of the Al layer to form a seal that reduces or prevents volatile component loss.10-07-2010
20100292660DERMAL DELIVERY DEVICE WITH ULTRASONIC WELD - A method of enclosing an active ingredient layer between a release liner and a backing layer of a dermal patch by ultrasonically welding a seal between the backing layer and the release liner. A pressure sensitive layer is further provided between the backing layer and release liner.11-18-2010

Agis Kydonieus, Kendell Park, NJ US

Patent application numberDescriptionPublished
20090203803N-acylated chitinous polymers and methods of use thereof - The invention pertains to N-acetylated, N, O-carboxyalkylchitosans and methods for using the chitosans to treat disorders, such as cancer, nervous system disorders, urinary tract disorders, and reproductive tract disorders.08-13-2009
20100190743Method and Composition for Treatment of a Mucosal Tissue Disorder - Methods of treating a subject suffering from a disorder in a mucosal tissue, such as interstitial cystitis; cancer in a mucous membrane such as bladder or vaginal cancer; Crohn's disease; inflammatory bowel disease or colitis, by administering a medicament containing a sulfated chitinous polymer administered topically are described. Pharmaceutical compositions containing the sulfate chitinous polymer are also disclosed.07-29-2010

Patent applications by Agis Kydonieus, Kendell Park, NJ US