Patent application number | Description | Published |
20080312337 | Anticancer Composition Comprising Obovatol or Obovatal - Disclosed herein is an anticancer composition, comprising obovatol, represented by the following Chemical Formula 1, obovatal, represented by the following Chemical Formula 2, and/or pharmaceutical salts thereof. The composition exhibits the activity of inhibiting the growth of cancer cells and suppressing the expression and activity of matrix metalloproteinases (MMPs), and thus can be useful for the prophylaxis and treatment of cancer as well as for the inhibition of cancer metastasis. | 12-18-2008 |
20090317374 | COMPOSITION CONTAINING ARAZYME FOR THE PREVENTION AND TREATMENT OF CANCER - The present invention relates to a pharmaceutical composition for the prevention and treatment of cancer comprising arazyme as an active ingredient. More precisely, when arazyme produced by | 12-24-2009 |
20090318376 | High Throughput Screening Method of Binding Inhibitor Between caspase3 and XIAP and Binding Inhibitor Screened Thereby - The present invention relates to a high throughput screening method of a binding inhibitor between caspase3 and xIAP and chromomycin screened using the same, and more specifically, the present invention provides a method for screening anticancer substance, the method comprising the steps of reacting caspase3 or xIAP and candidate inhibitors of the binding between caspase3 and xIAP on a biochip for detecting caspase3:xIAP interaction, and selecting a candidate substance inhibiting the binding of caspase3 to xIAP as an anticancer substance, and an anticancer agent inhibiting caspase3:xIAP binding, which is screened by the above method. According to present invention, it is possible to develop a target-oriented anticancer agent focused on xIAP and caspase3, apoptosis-related proteins and thus it can be applied to tailored medication and combination therapy. Moreover, glycoside antibiotic chromomycin, screened by the present invention has inhibitory activity of the binding between xIAP and caspase3 involved in apoptosis, so that it can be used as a therapeutic agent for myelogenous leukemia and solid tumors. | 12-24-2009 |
20100278806 | Composition Containing Arazyme for the Prevention and Treatment of Arthritis - Disclosed herein is a composition containing arazyme as an active ingredient for prevention and treatment of arthritis. More specifically, arazyme produced from | 11-04-2010 |
20100322917 | PHARMACEUTICAL COMPOSITION CONTAINING ARAZYME FOR THE PREVENTION OF LIVER DYSFUNCTION - The present invention relates to a pharmaceutical composition for the prevention of liver dysfunction which contains arazyme as an active ingredient, more precisely a pharmaceutical composition for the prevention of liver dysfunction which contains arazyme produced by | 12-23-2010 |
20120003204 | COMPOSITION CONTAINING ARAZYME FOR THE PREVENTION AND TREATMENT OF CANDER - The present invention relates to a pharmaceutical composition for the prevention and treatment of cancer comprising arazyme as an active ingredient. More precisely, when arazyme produced by | 01-05-2012 |
20120003205 | PHARMACEUTICAL COMPOSITION CONTAINING ARAZYME FOR THE PREVENTION OF LIVER DYSFUNCTION - The present invention relates to a pharmaceutical composition for the prevention of liver dysfunction which contains arazyme as an active ingredient, more precisely a pharmaceutical composition for treating liver dysfunction which contains arazyme produced by | 01-05-2012 |
20120309074 | NOVEL XYLANASE PRODUCED FROM CELLULOSIMICROBIUM FUNKEI HY-13 - There are provided a novel xylanase and a use of the same. In detail, there are provided a xylanase separated from a | 12-06-2012 |
20130165635 | CLONING AND BASE SEQUENCE DETERMINATION OF NOVEL ITURIN BIOSYNTHESIS GENE FROM ANTAGONISTIC MICROORGANISM BACILLUS SUBTILIS AND CHARACTERISTICS OF THE GENE - The present invention relates to novel iturin biosynthesis genes, and uses thereof. More specifically, the present invention provides novel iturin biosynthesis genes, wherein the iturin biosynthesis genes were cloned from | 06-27-2013 |