Patent application number | Description | Published |
20110033384 | CHIMERIC POLYPEPTIDES AND THEIR USE - The presented invention concerns chimeric molecules that contain a preferential polypeptidic region, consisting of a specific affinity for the binding to specific DNA sequences, of a preferential polypeptidic region consisting of a DNA modifying activity, and this chimeric molecule is capable to cross biological membranes due to the presence of a region that contains delivery activity. The invention contains further the isolated polynucleotides that code for the chimeric molecules of the invention if they are as such entirely or partially of polypeptide nature. | 02-10-2011 |
20150018409 | CHIMERIC POLYPEPTIDES AND THEIR USE - The presented invention concerns chimeric molecules that contain a preferential polypeptidic region, consisting of a specific affinity for the binding to specific DNA sequences, of a preferential polypeptidic region consisting of a DNA modifying activity, and this chimeric molecule is capable to cross biological membranes due to the presence of a region that contains delivery activity. The invention contains further the isolated polynucleotides that code for the chimeric molecules of the invention if they are as such entirely or partially of polypeptide nature. | 01-15-2015 |
20150023979 | Antibodies Against E7 Protein of Human Papilloma Virus (HPV) - The invention discloses a method for preparing Human Papilloma Virus protein E7 antigen (HPV E7 antigen) comprising the following steps: —providing a purified preparation of HPV protein E7; —phosphorylating the HPV protein E7 in the preparation; —purifying the phosphorylated E7 protein with an anion exchange chromatography, wherein the phosphorylated E7 protein is separated from the non-phosphorylated E7 protein by a step wherein the non-phosphorylated E7 protein stays bound to an anion exchanger during the anion exchange chromatography whereas the phosphorylated E7 protein is obtained in the eluate of the anion exchange chromatography, thereby—obtaining a purified preparation of a phosphorylated HPV protein E7 antigen. The invention further discloses antibodies specific to this antigen, a kit and method for using such antibodies in clinical diagnostics and methods for generation of such antibodies. | 01-22-2015 |
Patent application number | Description | Published |
20100104508 | HUMAN ANTIBODIES THAT BIND CXCR4 AND USES THEREOF - The present disclosure provides isolated monoclonal antibodies that specifically bind to CXCR4 with high affinity, particularly human monoclonal antibodies. Nucleic acid molecules encoding the antibodies of this disclosure, expression vectors, host cells and methods for expressing the antibodies of this disclosure are also provided. Immunoconjugates, bispecific molecules and pharmaceutical compositions comprising the antibodies of this disclosure are also provided. This disclosure also provides methods for detecting CXCR4, as well as methods for treating various cancers, inflammatory disorders and HIV infection using an anti-CXCR4 antibody of this disclosure. | 04-29-2010 |
20130251729 | HUMAN MONOCLONAL ANTIBODIES THAT BIND CXCR4 AND USES THEREOF - The present disclosure provides isolated monoclonal antibodies that specifically bind to CXCR4 with high affinity, particularly human monoclonal antibodies. Nucleic acid molecules encoding the antibodies of this disclosure, expression vectors, host cells and methods for expressing the antibodies of this disclosure are also provided. Immunoconjugates, bispecific molecules and pharmaceutical compositions comprising the antibodies of this disclosure are also provided. This disclosure also provides methods for detecting CXCR4, as well as methods for treating various cancers, inflammatory disorders and HIV infection using an anti-CXCR4 antibody of this disclosure. | 09-26-2013 |
Patent application number | Description | Published |
20120062566 | Methods And Systems For Stylized Map Generation - Systems, methods and articles of manufacture for stylized map generation are described herein. An embodiment includes enabling a user to provide a geographical region of interest, retrieving a multi-dimensional data set associated with the region of interest, determining an area outline of the region of interest based on an intersection of the data set with the region of interest, and generating a graphical representation of the region of interest and the area outline based on the data set. The embodiment further comprises instantiating a shader to generate the area outline and obtaining a shader algorithm to configure the shader. An embodiment includes applying a style package to the generated representation and modifying the style package using the shader algorithm. In this way, embodiments of the invention enable creation of stylized maps to visualize information associated with a geographical region. | 03-15-2012 |
20120120104 | Simplified Creation of Customized Maps - Embodiments of the present invention relate to providing a method for creating customized labeled maps that include displaying a map using a presentation device based on a selectable elevation value, where the map contains geocoded information and the user selects at least one position on the displayed map. The method continues by automatically creating and displaying at least one label located in proximity to the selected position, where at least one label is based on reverse geocoded information associated with the selected position. | 05-17-2012 |
20140071063 | INTERACTING WITH RADIAL MENUS FOR TOUCHSCREENS - The subject technology discloses configurations for providing a radial menu on one or more computing devices with a touch-sensitive screen. In one example, a user activates the radial menu after touching a first finger at a first or anchor point on a touchscreen that serves as a center of the radial menu. While the first finger is disposed, the user then touches a second finger at a second point some distance from the anchor point corresponding to the first finger on the touchscreen. The radial menu is generated based on a distance calculated between the anchor point and the second finger at the second point. The radial menu is not a complete circle and instead displayed as a partial circle, and the radial menu is generated so that the display area is bisected from the anchor point to the second point in some configurations. | 03-13-2014 |
20140075388 | PROVIDING RADIAL MENUS WITH TOUCHSCREENS - The subject technology discloses configurations for providing a radial menu on one or more computing devices with a touch-sensitive screen. In one example, a user activates the radial menu after touching a first finger at a first or anchor point on a touchscreen that serves as a center of the radial menu. While the first finger is disposed, the user then touches a second finger at a second point some distance from the anchor point corresponding to the first finger on the touchscreen. The radial menu is generated based on a distance calculated between the anchor point and the second finger at the second point. The radial menu is not a complete circle and instead displayed as a partial circle, and the radial menu is generated so that the display area is bisected from the anchor point to the second point in some configurations. | 03-13-2014 |
20140164989 | DISPLAYING WINDOWS ON A TOUCHSCREEN DEVICE - A system and machine-implemented method for displaying windows on a touchscreen device. Plural graphical objects are displayed on a touchscreen of the touchscreen device, each graphical object being associated with an application. Multiple touch presses that are at least partially overlapping in time are detected on the touchscreen, each touch press corresponding to a respective one of the plural graphical objects. The applications associated with the graphical objects corresponding to the multiple touch presses are identified. A release of the multiple touch presses is detected. In response to detecting the release, a display arrangement to reduce overlapping of windows for the identified applications is determined. The windows for the identified applications are displayed on the touchscreen based on the determined display arrangement. | 06-12-2014 |
20140237421 | INTELLIGENT WINDOW PLACEMENT WITH MULTIPLE WINDOWS USING HIGH DPI SCREENS - The subject technology discloses configurations for determining a minimum dots per inch (DPI) setting for displaying graphical content in a window based on a native pixel density of a display. Respective graphical content is scaled for displaying in a first window based on the minimum DPI setting to fit a horizontal dimension of the first window. The subject technology then scales respective graphical content for displaying in a second window based on the minimum DPI setting to fit a horizontal dimension of the second window. In some configurations, the graphical content in the first window is scaled at a different DPI setting than the graphical content in the second window. | 08-21-2014 |
20150205425 | SYSTEM AND METHOD FOR PROCESSING TOUCH ACTIONS - A system and method for processing touch actions are provided. A plurality of sequentially performed touch actions including a first touch action and a second touch action are determined on a touch interface of an electronic device. An initiation location and a completion location of each of the first and second touch actions are determined on the touch interface. A command is selected based on the determined completion location of the first touch action, the second touch action, and the determined initiation location of the second touch action. The selected command is executed on the electronic device. | 07-23-2015 |
20150205516 | SYSTEM AND METHOD FOR PROCESSING TOUCH INPUT - A system and method for processing a touch input are provided. An initial press action that is associated with a number of simultaneous touches is detected on a touch interface. One or more commands that are mapped to one or more sequences of user interaction is determined based on the number of simultaneous touches, where each of the one or more sequences of user interaction is initiated by the initial press action. One or more graphical interface components, where each of the one or more graphical interface components correspond to a different one of the one or more sequences of user interaction are provided for display. Each of the one or more graphical interface components indicate at least part of the corresponding sequence of user interaction and indicates respective command mapped to the corresponding sequence of user interaction. | 07-23-2015 |
Patent application number | Description | Published |
20090156981 | Flexible Catheter for High-Frequency Therapy of Biological Tissue and Method of Using Same - A catheter for the high-frequency therapy of body lumens has a flexible shaft tube ( | 06-18-2009 |
20100087814 | DEVICE FOR CUTTING AND COAGULATING TISSUE - The invention concerns an application device for electrosurgical cutting and coagulation of body tissue, wherein the instrument is in the form of a gripping instrument having two gripping arms which are movable relative to each other and which each have at their distal end at least two respective electrodes, namely at least one coagulation electrode and at least one cutting electrode. | 04-08-2010 |
20100093226 | MEDICAL TECHNOLOGY DEVICE AND MEDICAL TECHNOLOGY DEVICE ARRANGEMENT - The invention concerns a medical technology device for treatment of the human or animal body, comprising at least one electrical plug connector which is adapted to be connected to a complementary counterpart plug connector of a further medical technology device and which in an active position is arranged projecting upwardly at the top side of the device. To provide a medical technology device which can be used both as an individual device and also in conjunction with a second device as a device arrangement and which in that respect satisfies existing safety and aesthetic demands, it is provided in accordance with the invention that the plug connector is adapted to be movable from the active position into a passive position, wherein in the passive position the plug connector is removed from the top side of the device and the top side is closed in substantially fluid-tight relationship. | 04-15-2010 |
20100233913 | HIGH FREQUENCY SURGICAL DEVICE - The invention relates to a high frequency surgical device for generating high frequency energy for separating and/or coagulating of biological tissue, comprising at least one energy source and at least one output socket, into which a longitudinally extending electrically conductive plug contact of an electrosurgical instrument can be inserted, and which output socket comprises a catch for engaging an opposite catch configured in the plug contact, wherein a socket contact is electrically insulated from the catch, which socket contact is electrically connected to the energy source. | 09-16-2010 |
20120316588 | MEDICAL TECHNOLOGY DEVICE AND MEDICAL TECHNOLOGY DEVICE ARRANGEMENT - The invention concerns a medical technology device for treatment of the human or animal body, comprising at least one electrical plug connector which is adapted to be connected to a complementary counterpart plug connector of a further medical technology device and which in an active position is arranged projecting upwardly at the top side of the device. To provide a medical technology device which can be used both as an individual device and also in conjunction with a second device as a device arrangement and which in that respect satisfies existing safety and aesthetic demands, it is provided in accordance with the invention that the plug connector is adapted to be movable from the active position into a passive position, wherein in the passive position the plug connector is removed from the top side of the device and the top side is closed in substantially fluid-tight relationship. | 12-13-2012 |
Patent application number | Description | Published |
20100087814 | DEVICE FOR CUTTING AND COAGULATING TISSUE - The invention concerns an application device for electrosurgical cutting and coagulation of body tissue, wherein the instrument is in the form of a gripping instrument having two gripping arms which are movable relative to each other and which each have at their distal end at least two respective electrodes, namely at least one coagulation electrode and at least one cutting electrode. | 04-08-2010 |
20100093226 | MEDICAL TECHNOLOGY DEVICE AND MEDICAL TECHNOLOGY DEVICE ARRANGEMENT - The invention concerns a medical technology device for treatment of the human or animal body, comprising at least one electrical plug connector which is adapted to be connected to a complementary counterpart plug connector of a further medical technology device and which in an active position is arranged projecting upwardly at the top side of the device. To provide a medical technology device which can be used both as an individual device and also in conjunction with a second device as a device arrangement and which in that respect satisfies existing safety and aesthetic demands, it is provided in accordance with the invention that the plug connector is adapted to be movable from the active position into a passive position, wherein in the passive position the plug connector is removed from the top side of the device and the top side is closed in substantially fluid-tight relationship. | 04-15-2010 |
20120316588 | MEDICAL TECHNOLOGY DEVICE AND MEDICAL TECHNOLOGY DEVICE ARRANGEMENT - The invention concerns a medical technology device for treatment of the human or animal body, comprising at least one electrical plug connector which is adapted to be connected to a complementary counterpart plug connector of a further medical technology device and which in an active position is arranged projecting upwardly at the top side of the device. To provide a medical technology device which can be used both as an individual device and also in conjunction with a second device as a device arrangement and which in that respect satisfies existing safety and aesthetic demands, it is provided in accordance with the invention that the plug connector is adapted to be movable from the active position into a passive position, wherein in the passive position the plug connector is removed from the top side of the device and the top side is closed in substantially fluid-tight relationship. | 12-13-2012 |