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Kuhara, JP

Motoki Kuhara, Nagano JP

Patent application numberDescriptionPublished
20080248011Methods for Isolating Monocytes - The present invention provides HIDE1 as novel monocyte markers. Since HIDE1 are membrane proteins, monocytes can be specifically detected by using antibodies that bind to HIDE1. Further, HIDE1-positive monocytes can also be collected from peripheral blood or the like using a cell sorter, magnet, or such. Monocytes that can be prepared based on the present invention are useful in cell immunotherapy.10-09-2008

Satoru Kuhara, Fukuoka JP

Patent application numberDescriptionPublished
20090263888KOJI MOLD-ORIGIN PHOSPHOLIPASE A2 - It is intended to provide koji mold-origin phospholipase A10-22-2009

Patent applications by Satoru Kuhara, Fukuoka JP

Shigehide Kuhara, Otawara-Shi JP

Patent application numberDescriptionPublished
20080200800RESPIRATION SUPPRESSING MAT AND MAGNETIC RESONANCE IMAGING APPARATUS AND METHOD - A respiration suppressing member includes a main body of an elastic material which is formed into a shape having a pressurizing portion for pressurizing that portion of the abdomen of a subject under imaging diagnosis by a medical modality which is located below the sternum and between the right and left ribs of the subject.08-21-2008
20080231271Magnetic resonance imaging apparatus and magnetic resonance imaging method - An MRI apparatus includes an imaging signal acquisition unit, a motion signal acquisition unit, a motion amount determination unit, a motion correction unit and an image reconstruction unit. The imaging signal acquisition unit acquires MR signals as imaging signals. The motion signal acquisition unit repetitively acquires MR signals having PE amount less than that of the imaging signals as motion signals. The motion amount determination unit obtains a motion amount using the motion signals. The motion correction unit performs correction processing of the imaging signals in accordance with the motion amount. The image reconstruction unit reconstructs an image using the imaging signals after the correction processing.09-25-2008
20080281186Magnetic resonance imaging apparatus and control method thereof - A magnetic resonance imaging apparatus includes a collection unit which applies a uniform static magnetic field to a subject and also applies a radio-frequency magnetic field and a gradient magnetic field to the subject in accordance with a predetermined pulse sequence to collect a magnetic resonance signal from the subject, a imaging unit which images the subject based on the magnetic resonance signal collected by the collection unit, a detection unit which detects a respiratory level of the subject, an informing unit which informs the subject of whether the detected respiratory level falls within an allowable range, and a unit which controls the collection unit and the imaging unit in such a manner that the magnetic resonance signal for imaging is collected and the subject is imaged based on the thus collected magnetic resonance signal for imaging when the detected respiratory level falls within the allowable range.11-13-2008
20100094121MAGNETIC RESONANCE IMAGING APPARATUS AND MAGNETIC RESONANCE IMAGING METHOD - A magnetic resonance imaging apparatus includes a collection unit which collects a magnetic resonance signal from the subject by applying a uniform static magnetic field to a subject and also applies a radio-frequency magnetic field and a gradient magnetic field to the subject in accordance with a predetermined pulse sequence, a reconstruction unit which reconstructs an image concerning the subject based on the magnetic resonance signal collected by the collection unit, a detection unit which detects a respiration level of the subject, a control unit which controls the reconstruction unit to reconstruct the image based on the magnetic resonance signal collected by the collection unit in a state wherein a peak of the detected respiration level falls within an allowable range, and a change unit which changes the allowable range based on a change in a plurality of peak values of a plurality detected respiration levels.04-15-2010
20110071382MAGNETIC RESONANCE IMAGING APPARATUS AND MAGNETIC RESONANCE IMAGING METHOD - According to one of the aspects of an MRI apparatus of the present invention, the MRI apparatus includes an imaging data acquiring unit and a blood flow information generating unit. The imaging data acquiring unit acquires imaging data from an imaging region including myocardium, without using a contrast medium, by applying a spatial selective excitation pulse to a region including at least a part of an ascending aorta for distinguishably displaying inflowing blood flowing into the imaging region. The blood flow information generating unit generates blood flow image data based on the imaging data.03-24-2011

Patent applications by Shigehide Kuhara, Otawara-Shi JP

Tetsuya Kuhara, Kanagawa JP

Patent application numberDescriptionPublished
20100221745ABNORMAL PRION PROTEIN BINDER, AND METHOD FOR DETECTION OF ABNORMAL PRION PROTEIN - Disclosed are: a method for detecting pathogenic isoform of prion protein as distinguished from normal prion protein in a simple manner, rapidly, with a high degree of sensitivity and quantitatively without the need of the enzymatic treatment with protease K; and a reagent for use in the method. Specifically disclosed are: a pathogenic isoform of prion protein binder which comprises lactoferrin; and a method for detecting pathogenic isoform of prion protein by using the pathogenic isoform of prion protein binder.09-02-2010

Tetsuya Kuhara, Zama-Shi JP

Patent application numberDescriptionPublished
20080287365DRUG AND METHOD FOR PROLIFERATING NATURAL KILLER CELLS - Natural Killer (NK) cells are obtained by administering a Toll-like receptor ligand such as polyinosinic-polycytidylic acid into the peritoneal cavity of an animal to which lactoferrin has been administered to proliferate NK cells in the peritoneal cavity and collecting NK cells from the peritoneal cavity.11-20-2008