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Kucera, US

Bradley K. Kucera, Lakeville, MN US

Patent application numberDescriptionPublished
20120121238APPARATUS AND METHODS FOR DELIVERING A HEATED FLUID - Herein are disclosed apparatus and methods for delivering a heated fluid. The apparatus comprises at least a preheat zone, an expansion zone, and an expanded zone comprising a plurality of trim heaters, at least one fluid flow-distribution sheet, and an outlet.05-17-2012

Curtis C. Kucera, Temecula, CA US

Patent application numberDescriptionPublished
20120125959MONITOR-MOUNTING SYSTEM FOR A LAND VEHICLE HEADREST - A monitor-mounting system for a headrest of a land vehicle includes a bushing subsystem constructed to be coupled to the headrest; and a monitor-mounting plate constructed to be coupled to the bushing subsystem. The monitor-mounting region extends outwardly of the headrest and is constructed for fixedly receiving a monitor. The headrest is constructed with dual posts and dual post guides, and the bushing system is constructed with dual bushings, each being constructed to couple to a corresponding one of the dual post guides, or to a corresponding one of the posts.05-24-2012

David Kucera, Del Mar, CA US

Patent application numberDescriptionPublished
20090105473PYRRO[1,2-b]PYRIDAZINONE COMPOUNDS - The invention is directed to pyrro[1,2-b]pyridazinone compounds and pharmaceutical compositions containing such compounds that are useful in treating infections by hepatitis C virus.04-23-2009
20090197826P-Toluene Sulfonic Acid Salt of 5-Amino-3-(2'-O-Acetyl-3'-Deoxy-Beta-D-Ribofuranosyl)-3H-Thiazole[4,5-d]p- yrimidine-2-one and Methods for Preparation - The present disclosure relates to p-toluene sulfonic acid salt of 5-amino-3-(2′-O-acetyl-3′-deoxy-beta-D-ribofuranosyl)-3H-thiazolo[4,5-d]pyrimidin-2-one and to its use in treating conditions such as viral infections, tumors, and cancer.08-06-2009
20090312570PYRRO[1,2-b]PYRIDAZINONE COMPOUNDS - The invention is directed to pyrro[1,2-b]pyridazinone compounds and pharmaceutical compositions containing such compounds that are useful in treating infections by hepatitis C virus.12-17-2009
201000347735,6-DIHYDRO-1H-PYRIDIN-2-ONE COMPOUNDS - The invention is directed to 5,6-dihydro-1H-pyridin-2-one compounds and pharmaceutical compositions containing such compounds that are useful in treating infections by hepatitis C virus.02-11-2010
201101663445,6-DIHYDRO-1H-PYRIDIN-2-ONE COMPOUNDS - The invention is directed to 5,6-dihydro-1H-pyridin-2-one compounds of Formula I07-07-2011
20110172447METHOD FOR PREPARING FURANOSE COMPOUNDS - The present disclosure relates to p-toluene sulfonic acid salt of 5-amino-3-(2′-O-acetyl-3′-deoxy-beta-D-ribofuranosyl)-3H-thiazolo[4,5-d]pyrimidin-2-one and to its use in treating conditions such as viral infections, tumors, and cancer.07-14-2011

Patent applications by David Kucera, Del Mar, CA US

Gregory L. Kucera, Winston-Salem, NC US

Patent application numberDescriptionPublished
20100184718Compositions and Methods for Double-Targeting Virus Infections and Targeting Cancer Cells - The invention includes compositions and methods useful for treatment of a virus infection in a mammal by double-targeting the virus (i.e. targeting the virus at more than one stage of the virus life cycle) and thereby inhibiting virus replication. The compositions of the invention include compounds which comprise a phosphocholine moiety covalently conjugated with one or more antiviral agents (e.g. nucleoside analogue, protease inhibitor, etc.) to a lipid backbone. The invention also includes pharmaceutical compositions and kits for use in treatment of a virus infection in mammals. The methods of the invention comprise administering a compound of the invention, a pharmaceutically acceptable salt thereof, or a pharmaceutical composition of the invention, in an amount effective to treat the infection, to a mammal infected with a virus. Additionally, the invention includes compositions and methods useful for combating a cancer in a mammal and for facilitating delivery of a therapeutic agent to a mammalian cell. The compositions of the invention include compounds which comprise an alkyl lipid or phospholipid moiety covalently conjugated with an anticancer agent (e.g. a nucleoside analogue). The invention also includes pharmaceutical compositions and kits for combating a cancer and for facilitating delivery of a therapeutic agent to a mammalian cell. The methods of the invention comprise administering a compound of the invention, a pharmaceutically acceptable salt thereof, or a pharmaceutical composition of the invention, in an amount effective to combat a cancer or to facilitate delivery of a therapeutic agent to a mammalian cell.07-22-2010

James P. Kucera, Spokane, WA US

Patent application numberDescriptionPublished
20080233795Electrical connector enclosure - An electrical connector enclosure which includes a framework having at least one wall, and which at least partly defines an internal cavity; and a moveable panel mounted on the framework, the panel being moveable between an open position and a closed position relative to the internal cavity, and wherein the at least one wall and the moveable panel cooperate to define a conductor aperture when the moveable panel is located in the closed position relative to the internal cavity.09-25-2008

Jeffrey R. Kucera, Parma Heights, OH US

Patent application numberDescriptionPublished
20080307762Bagging Lawn Mower with Selective Mulch or Discharge Options - A multi-use lawn mower capable of operating as a mulching, side-discharge, or a bagging mower. The lawn mower (12-18-2008

Jiri Kucera, Cupertino, CA US

Patent application numberDescriptionPublished
20090007846DIFFUSER GRAVITY SUPPORT - An apparatus and method for supporting a substantial center portion of a gas distribution plate is disclosed. At least one support member is capable of engaging and disengaging the diffuser with a mating connection without prohibiting flow of a gas or gases through the diffuser and is designed to provide vertical suspension to a diffuser that is supported at its perimeter, or capable of supporting the diffuser without a perimeter support. In one aspect, the at least one support member is a portion of a gas delivery conduit and in another embodiment is a plurality of support members separated from the gas delivery conduit. The at least one support member is capable of translating vertical lift, or vertical compression to a center area of the diffuser. A method and apparatus for controlling gas flow from the gas delivery conduit to the gas distribution plate is also disclosed.01-08-2009

John Kucera, San Francisco, CA US

Patent application numberDescriptionPublished
20110302222SYSTEM, METHOD AND COMPUTER PROGRAM PRODUCT FOR CREATING A CHILD DATABASE OBJECT USING A CHILD DATABASE OBJECT TYPE IDENTIFIED FROM A PARENT DATABASE OBJECT - In accordance with embodiments, there are provided mechanisms and methods for creating a child database object using a child database object type identified from a parent database object. These mechanisms and methods for creating a child database object using a child database object type identified from a parent database object can enable embodiments to provide creation of a child database object according to a type configured with respect to an associated parent database object. The ability of embodiments to provide such configuration in the parent database object can enable any associated child database objects to be created according to the type configured with respect to the parent database object.12-08-2011
20120096046Methods and Apparatus for Discontinuing the Following of Records in an On-Demand Database Service Environment - Disclosed are systems, apparatus, methods, and computer readable media for discontinuing the following of records in an on-demand database service environment. In one embodiment, one or more records are identified according to one or more designated criteria. The records are stored in a database. The records are being followed by one or more users in an on-demand database service environment such that updates to the records are capable of being stored as feed items in one or more feed tables in the database. The feed items are capable of being published in an information feed displayed on one or more devices associated with the one or more users. The following of the identified one or more records by the one or more users is discontinued.04-19-2012

Louis S. Kucera, Pfaffown, NC US

Patent application numberDescriptionPublished
20100273740Phospholipids for the Treatment of Infection by Togaviruses, Herpes Viruses and Coronaviruses - Provided are compounds, methods and pharmaceutical compositions for treating a host, especially a human, infected with a togavirus, herpes virus and/or coronavirus, and in particular SARS-CoV, cytomegalovirus or varicella-zoster virus. The method in one embodiment comprises administering to that host an effective amount of an anti-togavirus, anti-herpes virus and/or anti-coronavirus phospholipid or a pharmaceutically acceptable salt or prodrug thereof. The phospholipid compound is, e.g., a 3-alkylamido-2-alkoxypropylphosphocholine compound or salt thereof. The compound may be administered alone or in combination and/or alternation with one or more other anti-viral agents.10-28-2010

Louis S. Kucera, Pfafftown, NC US

Patent application numberDescriptionPublished
20080293667Lipid analogs for combating tumors - The invention relates to methods of treating viral infections, and in particular hepatitis B virus. The method comprises administering to a subject in need of such treatment an infection-controlling amount of a phospholipid or phospholipid derivative to inhibit the activity of the viral infection.11-27-2008
20100184718Compositions and Methods for Double-Targeting Virus Infections and Targeting Cancer Cells - The invention includes compositions and methods useful for treatment of a virus infection in a mammal by double-targeting the virus (i.e. targeting the virus at more than one stage of the virus life cycle) and thereby inhibiting virus replication. The compositions of the invention include compounds which comprise a phosphocholine moiety covalently conjugated with one or more antiviral agents (e.g. nucleoside analogue, protease inhibitor, etc.) to a lipid backbone. The invention also includes pharmaceutical compositions and kits for use in treatment of a virus infection in mammals. The methods of the invention comprise administering a compound of the invention, a pharmaceutically acceptable salt thereof, or a pharmaceutical composition of the invention, in an amount effective to treat the infection, to a mammal infected with a virus. Additionally, the invention includes compositions and methods useful for combating a cancer in a mammal and for facilitating delivery of a therapeutic agent to a mammalian cell. The compositions of the invention include compounds which comprise an alkyl lipid or phospholipid moiety covalently conjugated with an anticancer agent (e.g. a nucleoside analogue). The invention also includes pharmaceutical compositions and kits for combating a cancer and for facilitating delivery of a therapeutic agent to a mammalian cell. The methods of the invention comprise administering a compound of the invention, a pharmaceutically acceptable salt thereof, or a pharmaceutical composition of the invention, in an amount effective to combat a cancer or to facilitate delivery of a therapeutic agent to a mammalian cell.07-22-2010

Patent applications by Louis S. Kucera, Pfafftown, NC US

Mark Kucera, Howell, MI US

Patent application numberDescriptionPublished
20090026752Tabbed divider making apparatus and method - An improved tabbed divider making apparatus is disclosed. The machine preferably improves upon existing tabbed divider making machines in its ease of use and efficiency. Among other elements, the machine may include a paper feeder, a processing section, and an output tray. An improved film delivery system is also disclosed, as well as methods relating to manufacturing of tabbed dividers.01-29-2009
20090270237CUSTOMIZED TAB MACHINE - Disclosed is a tabbed divider making apparatus preferably adapted for use with smaller, more individualized jobs in an office or the like. The apparatus preferably includes a paper feeder, a film provider, a knife package for shearing a portion of the paper to create a tab, at least one strut, a pivotable arm, at least one spring, and a cam having an oblong shape. The rotation of the cam preferably causes movement between loaded and unloaded positions of the spring, which causes the knife package to shear the paper. Also disclosed is a removable film cartridge for use with the apparatus. The cartridge preferably includes a housing, a roll of film, one or more rollers, a creasing finger for creasing the film, and two or more opposed extensions for folding the film along the crease. Further disclosed is a method of producing a tabbed divider utilizing the above-mentioned apparatus.10-29-2009
20110065562CUSTOMIZED TAB MACHINE - Disclosed is a tabbed divider making apparatus preferably adapted for use with smaller, more individualized jobs in an office or the like. The apparatus preferably includes a paper feeder, a film provider, a knife package for shearing a portion of the paper to create a tab, at least one strut, a pivotable arm, at least one spring, and a cam having an oblong shape. The rotation of the cam preferably causes movement between loaded and unloaded positions of the spring, which causes the knife package to shear the paper. Also disclosed is a removable film cartridge for use with the apparatus. The cartridge preferably includes a housing, a roll of film, one or more rollers, a creasing finger for creasing the film, and two or more opposed extensions for folding the film along the crease. Further disclosed is a method of producing a tabbed divider utilizing the above-mentioned apparatus.03-17-2011

Paul Robert Kucera, Valrico, FL US

Patent application numberDescriptionPublished
20100028226EXTRACTION OF URANIUM FROM WET-PROCESS PHOSPHORIC ACID - A process for the extraction of uranium compounds from wet-process phosphoric acid includes lowering the iron concentration of the wet-process phosphoric acid and reducing the valency of any remaining ferric iron in the wet-process phosphoric acid to ferrous iron, and then extracting uranium compounds from the wet-process phosphoric acid. The process can include separating a side stream from a feed stream of wet-process phosphoric acid, wherein the side stream has a greater concentration of the uranium compounds than the feed stream by filtration. Extracting uranium compounds from the wet-process phosphoric acid can be by ion exchange process or by solvent extraction.02-04-2010

Rebecca Kucera, Hamilton, MA US

Patent application numberDescriptionPublished
20100173364Repair of Nucleic Acids for Improved Amplification - Methods and compositions are provided for repairing a polynucleotide so that it can be copied with improved fidelity and/o yield in, for example, an amplification reaction. This involves the use of a reaction mixture that includes a DNA ligase and an effective amount of at least one endonuclease as well as a cofactor selected from NAD07-08-2010
20110065182Modified DNA Cleavage and Methods for Use - Compositions and methods are provided that relate to a modified DNA cleaving enzyme having at least 35% amino acid sequence identity with T7 Endo I. The modified enzyme includes two catalytic centers separated by a β-bridge where the β-bridge contains at least one mutation having an effect of altering enzyme cleavage activity compared to the unmodified enzyme. Activities associated with the modified DNA cleaving enzyme that can be modulated in different reaction conditions include at least one of: (a) non-sequence specific nicking activity; (b) cleaving the second strand of a duplex DNA at a preexisting nick site to produce a linear duplex with a single strand overhang; (c) non-sequence specific DNA cleavage; (d) cleaving DNA flanking a mismatch; and (e) cleavage at a cruciform structure in a DNA duplex.03-17-2011

Patent applications by Rebecca Kucera, Hamilton, MA US