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Krzyzanowski

David Krzyzanowski, Lexington, KY US

Patent application numberDescriptionPublished
20090285603Toner Distribution Device For An Image Forming Apparatus - The present application is directed to devices to move toner within a toner reservoir of an image forming apparatus. The devices may include an elongated auger with a helical blade to move the toner. A gutter may be positioned adjacent to the auger and include a bottom section positioned vertically below the auger and a sidewall that extends upward along a lateral side of the auger. Apertures may be positioned along the bottom section of the gutter. The apertures may be sized to allow toner that is moved by the auger to fall through the gutter and into the reservoir11-19-2009

Gary D. Krzyzanowski, Omaha, NE US

Patent application numberDescriptionPublished
20120122073CIS DI-AHL MODIFIED CONTROLS FOR GLYCATED HEMOGLOBIN S-A1C DERIVED FROM HEALTHY BLOOD CELLS - The invention is composition comprising red blood cells in an aqueous suspension medium and one or more cis di-ahls; wherein more than 6 percent by weight of the hemoglobin in the red blood cells is S-Alc glycated hemoglobin. In another embodiment, the invention is a method comprising contacting red blood cells in a suspension medium having a concentration of S-Alc glycated hemoglobin of greater than 6 percent by weight of the hemoglobin in the red blood cells with a sufficient amount of one or more cis di-ahls such that the concentration of S-Alc glycated hemoglobin in resulting composition as measured by high pressure liquid chromatography, immunoassay and boronate affinity methods is consistent.05-17-2012

Jacek Krzyzanowski, Etobicoke CA

Patent application numberDescriptionPublished
20110092892Body passage cleansing device - The present invention provides a body passage cleansing device suitable for being passed through an internal channel of an endoscope, comprising a distal plug having a proximal end and a distal end, wherein said plug comprises channels, apertures and/or nozzles which are capable of allowing the passage of a fluid therethrough from said proximal end to said distal end, wherein said plug is connected to the distal end of a wire or other actuating means; wherein at least an outer portion of said distal plug is capable of being elastically deformed such that the external diameter and/or outline thereof may be reduced in response to inwardly-directed compression forces exerted thereon; and wherein said channels, apertures and/or nozzles are in a closed conformation when said distal plug is subject to said compression forces, and in an open conformation when said plug is not subject to said compression forces.04-21-2011
20110276085END EFFECTOR ASSEMBLY WITH INCREASED CLAMPING FORCE FOR A SURGICAL INSTRUMENT - An end effector assembly with increased clamping force for a surgical instrument including a hollow shaft having a proximal end and a distal end, a clevis coupled to the distal end of the hollow shaft, a flat support coupled to the clevis, a deflection member, a procedural member assembly rotatably coupled to the flat support and a pair of actuation means attached to the procedural member assembly and slidable relative to the hollow shaft for rotationally moving the procedural member assembly between a closed and an open position wherein the deflection member engaged the actuation means. The deflection member may be integral with the clevis, coupled to the clevis and the flat support, coupled to just the flat support, may be adjustable or rotatable or coupled to hollow shaft.11-10-2011

Mariusz Krzyzanowski, Skorcz PL

Patent application numberDescriptionPublished
20100069641PROCESS FOR THE PREPARATION OF SODIUM SALT OF 1-(((1(R)-(3-(2-(7-CHLORO-2-QUINOLINYL)-ETHENYL)PHENYL)-3-(2-(1-HYDROXY-1- -METHYLETHYL)PHENYL)PROPYL)SULFANYL)METHYL)CYCLOPROPANEACETIC ACID - A novel process for the preparation of a sodium salt of 1-(((1(R)-(3-(2-(7-chloro-2-quinolinyl)-ethenyl)phenyl)-3-(2-(1-hydroxy-1-methyl-ethyl)phenyl)propyl)sulfanyl)methyl)cyclopropaneacetic acid, comprising: a) reacting a compound of Formula 1 with methanesulfonyl chloride in the presence of a tertiary amine to yield a crude solution of a compound of Formula 2; b) filtering the crude solution of compound of Formula 2 obtained in a) to remove solid amine hydrochloride, reacting the filtrate without isolation or further purification with a compound of Formula 3, and isolating 1-(((1(R)-(3-(2-(7-chloro-2-quinolinyl)-ethenyl)phenyl)-3-(2-(1-hydroxy-1-methylethyl)phenyl)propyl)sulfanyl)methyl)cyclopropaneacetic acid; c) reacting the 1-(((1(R)-(3-(2-(7-chloro-2-quinolinyl)-ethenyl)phenyl)-3-(2-(1-hydroxy-1-methylethyl)phenyl)propyl)sulfanyl)methyl)cyclopropaneacetic acid isolated in b) with tert-butylamine to yield a compound of formula 4; d) isolating and purifying the compound of formula 4; and e) converting the compound of formula 4 to a compound of formula 5.03-18-2010
20120116092PROCESS FOR THE PREPARATION OF [1-HYDROXY-2-(1H-IMIDAZOL-1-YL)- ETHYLIDENE] BISPHOSPHONIC ACID - A process for the preparation of [1-hydroxy-2-(1H-imidazol-1-yl)-ethylidene]bisphosphonic acid consists of the reaction of aqueous solution of 1H-imidazole-1-acetic acid hydrochloride with phosphorus trichloride followed by removal of the excess of phosphorus trichloride, addition of water and hydrolysis of the reaction products. In order to isolate the product the post-reaction mixture is filtered and the anti-solvent is added to the aqueous filtrate in order to crystallize out [1-hydroxy-2-(1H-imidazol-1-yl)-ethylidene]bisphosphonic acid monohydrate.05-10-2012