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Krylov
Aleksandr Aleksandrovich Krylov, Moscow RU
Dmitriy Krylov, Red Bank, NJ US
| Patent application number | Description | Published |
|---|---|---|
| 20080259438 | BIDIRECTIONAL OPTICAL AMPLIFIER - A bidirectional amplification system and method are disclosed. A single optical line amplifier and isolation loss filters are used to amplify signals in both the east and west directions with sufficient gain along a fiber. | 10-23-2008 |
Evgeny Krylov, Franklin, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20110101214 | COUPLING DIFFERENTIAL MOBILITY BASED AMBIENT PRESSURE ION PREFILTERING AND ION FOCUSING AT LOW FLOW RATES FOR A PORTABLE MASS SPECTROMETER - A sample analysis apparatus and system including an ion inlet, an ion detector and an ion focusing assembly for converging a plurality of ion streams from the ion inlet into at least one focused ion stream. | 05-05-2011 |
Evgeny Krylov, Billerica, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20120025070 | METHOD AND APPARATUS FOR ENHANCED ION MOBILITY BASED SAMPLE ANALYSIS USING VARIOUS ANALYZER CONFIGURATIONS - A ion mobility-based analyzer system including a first ion mobility-based filter for passing selected ions through a time-varying field where the time-varying field being compensated by an adjustable compensation setting. The analyzer also includes a second ion mobility-based filter for receiving a first portion of ions from the first ion mobility-based filter. The second ion mobility-based filter includes a voltage gradient for separating ions of the first portion of ions where the ions have associated retention times based on their times of flight through the voltage gradient. The second ion mobility-based filter includes a detector for detecting the ions at their retention times. The analyzer system further includes a display that displays the detected ions in a plot relating the retention times of the ions in the second ion mobility-based filter with compensation settings of the first ion mobility-based filter. | 02-02-2012 |
Ivan S. Krylov, Los Angeles, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20110263535 | TYROSINE-BASED PRODRUGS OF ANTIVIRAL AGENTS - A tyrosine-based (phosphonylmethoxyalkyl)purine or -pyrimidine conjugate is provided. In some embodiments, the conjugate includes tyrosine based amino acid or dipeptide moieties of (S)-9-(3-hydroxy-2-phosphonyl-methoxypropyl)adenine or its cytosine analogue. A method of synthesizing such conjugates based on Boc-protected amino acid or dipeptides is also provided. In addition, a method of isomerizing an (S,S)-diastereoisomer to an (S,R)-diastereoisomer of an amino acid-based or dipeptide-based conjugate by a process including transesterification is provided. A method of inhibiting viral infection and a method of treating viral infection based on (phosphonylmethoxyalkyl)purine or -pyrimidine conjugates is also provided. | 10-27-2011 |
Sergey Krylov, Toronto CA
| Patent application number | Description | Published |
|---|---|---|
| 20100243450 | NON-EQUILIBRIUM CAPILLARY ELECTROPHORESIS OF EQUILIBRIUM MIXTURES (NECEEM)-BASED METHODS FOR DRUG AND DIAGNOSTIC DEVELOPMENT - The invention discloses a Non-Equilibrium Capillary Electrophoresis of Equilibrium Mixtures (NECEEM) method and NECEEM-based practical applications. The NECEEM method is a homogeneous technique, which, in contrast to heterogeneous methods, does not require affixing molecules to a solid substrate. The method of the invention facilitates 3 practical applications. In the first application, the method allows the finding of kinetic and thermodynamic parameters of complex formation. It advantageously allows for revealing two parameters, the equilibrium dissociation constant, K | 09-30-2010 |
Sergey Krylov, Concord CA
| Patent application number | Description | Published |
|---|---|---|
| 20090306461 | SPERM CELL SEPARATION METHODS AND COMPOSITIONS CONTAINING APTAMERS OR NUCLEIC ACID SEQUENCES FOR USE THEREIN - The present invention provides an aptamer or pool of aptamers (nucleic acid sequences) that bind(s) to a target molecule on the surface, accessible from the surface or inside of a mammalian sperm cell and a method for producing the aptamers. The method comprises contacting a collection of different nucleic acid molecules with the target molecule under conditions favorable for binding between at least one of the nucleic acid molecules and the target molecule, to form at least one complex comprising the nucleic acid molecule bound to the target molecule, wherein each of the nucleic acid molecules comprises at least one segment of randomized nucleotide sequences. The complexes are then separated from the unbound nucleic acid molecules and unbound target molecules, and the bound nucleic acid molecule is recovered from the separated complex. The aptamers are used to separate sperm cells based upon sperm cell qualities, such as whether the cells contain X chromosomes or Y chromosomes. | 12-10-2009 |
| 20100121135 | SPERM CELL SEPARATION METHODS AND COMPOSITIONS - The present invention provides an aptamer or pool of aptamers that bind(s) to a target molecule on the surface of a mammalian sperm cell and a method for producing the aptamers. The method comprises contacting a collection of different nucleic acid molecules with the target molecule under conditions favorable for binding between at least one of the nucleic acid molecules and the target molecule, to form at least one complex comprising the nucleic acid molecule bound to the target molecule, wherein each of the nucleic acid molecules comprises at least one segment of randomized nucleotide sequences. The complexes are then separated from the unbound nucleic acid molecules and unbound target molecules, and the bound nucleic acid molecule is recovered from the separated complex. The aptamers are used to separate sperm cells based upon sperm cell qualities, such as whether the cells contain X chromosomes or Y chromosomes. | 05-13-2010 |
S. Konstantin Krylov, Magnitogoskaya RU
| Patent application number | Description | Published |
|---|---|---|
| 20090289860 | ACTIVE MAGNETIC ANTENNA WITH FERRITE CORE - An active magnetic antenna with a ferrite core having a winding is provided, forming a frame magnetic antenna which is connected with a low-noise transistor, to amplify a signal of the frame magnetic antenna. A base of the transistor is connected directly to one contact of the winding, and a second contact of the winding is capable of shifting a voltage of the base of the transistor. The impedance of the frame magnetic antenna is adjusted as a complex conjugate with an impedance of the base of the transistor of the low-noise amplifier, and the winding eliminates its own resonances. | 11-26-2009 |
Slava Krylov, Holon IL
| Patent application number | Description | Published |
|---|---|---|
| 20100006958 | Tilting Actuator with Close-Gap Electrodes - An electromechanical tilting device including a first and a second electrode structures, shaped, positioned and oriented to define at least partially interdigitated electrodes, and a suspension defining a tilt-containing motion path for the second structure with respect to the first structure. The motion path is selected to cause changes in overlapping regions and overlapping regions' gaps of the interdigitated electrodes. The device is configured such that an increase in one or more voltage bias applied to interdigitated driving electrodes makes a decrease in a total area of overlapping regions of the driving electrodes electrically energetically favorable. | 01-14-2010 |
Viacheslav Krylov, Holon IL
| Patent application number | Description | Published |
|---|---|---|
| 20110048130 | Micro Scale Mechanical Rate Sensors - An angular rate sensor device is presented. The sensor device comprises a disk-shaped structure having a proof mass region and a flexible portion. The disk-like structure is coupled to a substrate in a manner enabling a wave type precession motion such that during the wave type precession motion each material point of the proof mass performs elliptic motion. | 03-03-2011 |
Vladimir G. Krylov, Brookline, NH US
| Patent application number | Description | Published |
|---|---|---|
| 20110157707 | System and Method for Adjusting a Projected Image - In accordance with one embodiment of the present disclosure, a system comprises a projection system. The system further includes an image generator disposed in the projection system. The image generator is operable to generate a plurality of rays. The system further includes an objective lens disposed in the projection system. The objective lens is operable to refract the plurality of rays. The system further includes a component operable to reflect the refracted rays onto a target in order to form an image. The image is operable to be moved in relation to the target. The movement of the image is independent of any displacement of the projection system in relation to the target. | 06-30-2011 |
Vladimir Vladimirovich Krylov, Nizhny Novgorod RU
| Patent application number | Description | Published |
|---|---|---|
| 20100223262 | METHOD AND SYSTEM FOR STORING, SEARCHING AND RETRIEVING INFORMATION BASED ON SEMISTRUCTURED AND DE-CENTRALIZED DATA SETS - A system for storage and methods for search and retrieval of information presentable as a plurality of tree-structured information objects of an arbitrary application domain are disclosed. The system comprises a distributed computer system consisting of computing devices, interconnected with each other by physical communication lines, and a connected logical storage network, every node of which is an active unit of storage (AUS), incorporating an information object, a program agent and a list of links of said AUS to a plurality of other AUS on the network, wherein the links form connections among the nodes of the logical storage network. Links of an AUS pointing at a plurality of other AUS are created based on a metric calculated taking into account the intrinsic structure of stored and retrieved information objects, and enabling determination and use of the degree of relevance between search information attributes and respective attributes of a search query. Methods for storing and retrieving information in the disclosed system are provided. The system and methods enable efficient storage, searching and retrieving information. | 09-02-2010 |