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Kronenberg, US
David Kronenberg, Sherborn, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20100078962 | Systems for Positioning and Linking Motor Vehicles to Reduce Aerodynamic Drag - A system for linking two or more vehicles to achieve reduced aerodynamic drag while the vehicles are travelling on the road is disclosed. The disclosed system not only physically connects the vehicles but also allows the driver of the leading vehicle to monitor and control essential functions of the trailing vehicles. Preferably, the driving mechanisms of the trailing vehicles, such as throttles, brakes, and gears, are fully operational so as not to put excessive burden on the driving mechanisms of the leading vehicle. Methods for linking individual vehicles as well as streamlining the operation of a fleet of vehicles are also disclosed. | 04-01-2010 |
| 20100082179 | Methods for Linking Motor Vehicles to Reduce Aerodynamic Drag and Improve Fuel Economy - Methods for linking two or more vehicles to achieve reduced aerodynamic drag while the vehicles are travelling on the road are disclosed. The disclosed methods utilize a dynamic linking system that not only physically connects the vehicles but also allows the driver of the leading vehicle to monitor and control essential functions of the trailing vehicles. Preferably, the driving mechanisms of the trailing vehicles, such as throttles, brakes, and gears, are fully operational so as not to put excessive burden on the driving mechanisms of the leading vehicle. Methods for linking individual vehicles as well as streamlining the operation of a fleet of vehicles are also disclosed. | 04-01-2010 |
Douglas M. Kronenberg, Prospect, KY US
| Patent application number | Description | Published |
|---|---|---|
| 20080300916 | HEALTH INCENTIVE MANAGEMENT FOR GROUPS - A method of presenting information to an administrator. The method includes the steps of accessing a library of actual expenditures on health care by an organization, generating a baseline based on the actual expenditures, enabling an administrator to reconfigure a health benefit plan and generating a display with impact information resulting from the administrator reconfiguring the health benefit plan. A method of optimizing a set of health incentives for an organization is also provided. | 12-04-2008 |
Harry Kronenberg, Fallbrook, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20110097966 | SELF-STANDING DISPLAY FIGURE - In accordance with one embodiment, a self-standing toy skeleton display includes a skeleton body that has a human form and is made of a plurality of connectable body parts that are each formed of bone structures. The connectable body parts at least includes a torso part that extends from a pelvic bone to a bottom end of a femur bone and a lower body part that extends from a top end of a tibia bone to foot bones. The skeleton toy display also includes an inner frame for supporting the skeleton in a standing manner. The inner frame passes through the femur bone and the tibia bone and is formed of separate upper and lower frame members that interlockingly mate with one another at an interface between the femur bones and the tibia bones. The lower frame member includes a pair of ground contacting portions that are mounted to an underside of the feet of the skeleton body with at least a portion of the ground contacting portion being located behind a heel portion of the foot to allow the assembled body parts of the skeleton to stand upright in a self-supporting manner, while permitting lower extremities thereof to move and be adjusted. | 04-28-2011 |
Henry Kronenberg, Belmont, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20090092625 | PARATHYROID HORMONE RECEPTOR ACTIVATION AND HEMATOPOIETIC PROGENITOR CELL EXPANSION - The invention relates to methods for manipulating hematopoietic progenitor cells and related products In one aspect the invention relates to the use of agents that activate a PTH/PTHrP receptor to enhance the growth and maintenance of hematopoietic progenitor cells in vivo and in vitro, to enhance mobilization of hematopoietic stem cells, to improve the efficiency of targeting cells to the bone marrow, and/or to modulate hematopoietic progenitor cell function. | 04-09-2009 |
| 20100113360 | PARATHYROID HORMONE RECEPTOR ACTIVATION AND STEM AND PROGENITOR CELL EXPANSION - The invention relates to methods for manipulating hematopoietic stem or progenitor cells, mesenchymal stem cells, epithelial stem cells, neural stem cells and related products through activation of the PTH/PTHrP receptor in neighboring cells. | 05-06-2010 |
Henry M. Kronenberg, Belmont, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20090264365 | CONFORMATIONALLY CONSTRAINED PARATHYROID HORMONE (PTH) ANALOGS - The present invention relates to conformationally constrained parathyroid hormone (PTH) analogs, and methods of preparing and using the PTH analogs. The invention provides novel PTH polypeptide derivatives containing amino acid substitutions at selected positions in the polypeptides. The invention provides derivatives of PTH(1-34), PTH(1-21), PTH(1-20), PTH(1-19), PTH(1-18), PTH(1-17), PTH(1-16), PTH(1-15), PTH(1-14), PTH(1-13), PTH(1-12), PTH(1-11), and PTH(1-10) polypeptides, wherein at least one residue in each polypeptide is a helix, preferably an α-helix, stabilizing residue. The invention also provides methods of making such peptides. Further, the invention encompasses compositions and methods for use in limiting undesired bone loss in a vertebrate at risk of such bone loss, in treating conditions that are characterized by undesired bone loss or by the need for bone growth, e.g., in treating fractures or cartilage disorders and for raising cAMP levels in cells where deemed necessary. | 10-22-2009 |
| 20100081612 | POLYPEPTIDE DERIVATIVES OF PARATHYROID HORMONE (PTH) - The present invention is related to novel parathyroid hormone polypeptide derivatives, and to pharmaceutical composition containing the polypeptides, as well as synthetic and recombinant methods for producing the polypeptides. Also disclosed are methods for treating mammalian conditions characterized by decreases in bone mass using therapeutically effective pharmaceutical compositions containing the polypeptides of the present invention. The present invention further provides diagnostic and therapeutic methods using the polypeptide derivatives. | 04-01-2010 |
| 20110009328 | Polypeptide Derivatives of Parathyroid Hormone (PTH) - Novel parathyroid hormone (PTH) polypeptide derivatives are disclosed, as are pharmaceutical compositions containing said polypeptides, and synthetic and recombinant methods for producing said polypeptides. Also disclosed are methods for treating mammalian conditions characterized by decreases in bone mass using therapeutically effective pharmaceutical compositions containing said polypeptides. Also disclosed are methods for screening candidate compounds of the invention for antagonistic or agonistic effects on parathyroid hormone receptor action. Also disclosed are diagnostic and therapeutic methods of said compounds. | 01-13-2011 |
Ira A. Kronenberg, New Orleans, LA US
| Patent application number | Description | Published |
|---|---|---|
| 20090018695 | VENDING MACHINE SERVICE SYSTEM AND METHOD THEREFORE - A mono-directional data transmission and receiving system between vending equipment and service vehicles is provided so as to allow service personnel the ability to retrieve information about the vending equipment prior to entering facilities and arriving at the equipment's location. The preferred embodiment of the present invention teaches a monitoring module configured to interface with a communications port or existing DEX/UCS port in a vending machine, the monitoring module configured to periodically poll the equipment to receive operational and/or inventory data, and/or cash data, along with an identifier for identifying the particular equipment, is transmitted to a reception area wherein a mobile service vehicle may be situated to receive said data via a receiver unit, which receiver unit is configured to interface with a portable computer so as to transfer said operational and/or inventory data. | 01-15-2009 |
Marc Kronenberg, San Diego, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20100048321 | MOVABLE WEIGHTS FOR A GOLF CLUB HEAD - Embodiments of movable weights, such as weight assemblies and weight screws, for a golf club head are disclosed herein. One embodiment for a weight assembly, for example, comprises a mass element having a first end, a second end and a sidewall extending between the first end and the send end. The sidewall of the mass element defines a first bore extending through the mass element and at least a portion of the sidewall of mass element tapers in a direction from the first end to the second end. This embodiment further includes a retaining element configured to engage the first bore adjacent the first end of the mass element and defining a second bore. The weight assembly further includes an elongate fastener having a first end configured to be received within the second bore of the retaining element and a second end extending through the first bore and beyond the second end of the mass element when the mass element, retaining element and fastener are assembled together. | 02-25-2010 |
Mark S. Kronenberg, Metairie, LA US
| Patent application number | Description | Published |
|---|---|---|
| 20090018695 | VENDING MACHINE SERVICE SYSTEM AND METHOD THEREFORE - A mono-directional data transmission and receiving system between vending equipment and service vehicles is provided so as to allow service personnel the ability to retrieve information about the vending equipment prior to entering facilities and arriving at the equipment's location. The preferred embodiment of the present invention teaches a monitoring module configured to interface with a communications port or existing DEX/UCS port in a vending machine, the monitoring module configured to periodically poll the equipment to receive operational and/or inventory data, and/or cash data, along with an identifier for identifying the particular equipment, is transmitted to a reception area wherein a mobile service vehicle may be situated to receive said data via a receiver unit, which receiver unit is configured to interface with a portable computer so as to transfer said operational and/or inventory data. | 01-15-2009 |
Mitchell Kronenberg, Del Mar, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20090311280 | NOVEL TNF RECEPTOR REGULATORY DOMAIN - Herpesvirus entry mediator (HVEM) is a member of the tumor necrosis factor receptor superfamily (TNFRSF) and acts as a molecular switch that modulates T cell activation by propagating positive signals from the TNF related ligand, LIGHT (p30, TNFSF14), or inhibitory signals through the immunoglobulin superfamily member, B and T lymphocyte attenuator (BTLA). A novel binding site for BTLA is disclosed, located in cysteine-rich domain-1 of HVEM. BTLA binding site on HVEM overlaps with the binding site for the Herpes Simplex virus-1 envelope glycoprotein D (gD), but is distinct from where LIGHT binds, yet gD inhibits the binding of both ligands. A BTLA activating protein present in human cytomegalovirus is identified as UL144. UL144 binds BTLA, but not LIGHT, and inhibits T cell proliferation. | 12-17-2009 |
| 20100104559 | US CIP-COMPOSITIONS AND METHODS FOR MODULATING RESPONSES MEDIATED OR ASSOCIATED WITH BTLA ACTIVITY - Herpesvirus entry mediator (HVEM) is a member of the tumor necrosis factor receptor superfamily (TNFRSF) and acts as a molecular switch that modulates T cell activation by propagating positive signals from the TNF related ligand, LIGHT (p30, TNFSF14), or inhibitory signals through the immunoglobulin superfamily member, B and T lymphocyte attenuator (BTLA). A novel binding site for BTLA is disclosed, located in cysteine-rich domain-1 of HVEM. BTLA binding site on HVEM overlaps with the binding site for the Herpes Simplex virus-1 envelope glycoprotein D (gD), but is distinct from where LIGHT binds, yet gD inhibits the binding of both ligands. A BTLA activating protein present in human cytomegalovirus is identified as UL144. UL144 binds BTLA, but not LIGHT, and inhibits T cell proliferation. | 04-29-2010 |
Sandy Craig Kronenberg, West Bloomfield, MI US
| Patent application number | Description | Published |
|---|---|---|
| 20090106421 | Network Monitoring System - Methods and systems consistent with the present invention solve the limitations of current monitoring systems by automatically and completely monitoring various networks devices and services. Specifically, a network monitoring system monitors all services and conditions on various networks. Moreover, the network monitoring system may provide an advance warning of potential failures and may diagnose an problems that may surface. | 04-23-2009 |