Inventors list |
Assignees list |
Classification tree browser |
Top 100 Inventors |
Top 100 Assignees |
Kridel
Michael D Kridel, Wooster, OH US
| Patent application number | Description | Published |
|---|---|---|
| 20090107623 | Continuous venting of a covering sheet for an in-situ lamination process - A method of venting a rear facer sheet for lamination is accomplished by continuously drawing the rear facer sheet through a perforating device which creates conical apertures in the rear facer. Two metal rails affixed to opposing edges of a front facer are continuously drawn into a laminator after first having an expanding foam material continuously deposited onto the upper surface of the front facer. The perforated rear facer is continuously drawn into the laminator and affixed to the two metal rails, creating an enclosed volume in which the expanding foam is located. The apertures in the rear facer allow for the escape of gasses and air during lamination, promoting even flow and uniform density of the foam material. The perforating device has an upper and a lower rotating cylinder, the lower cylinder being equipped with piercing elements and the upper cylinder being equipped with grooves corresponding to the piercing elements. | 04-30-2009 |
| 20090272069 | Movable barriers having transverse stiffeners and methods of making the same - A movable door panel having a front facer with opposed longitudinal edge profiles, rails secured to the longitudinal edge profiles, a rear facer secured to the rails, and foam disposed within an inner volume defined by the front facer, the rails and the rear facer is disclosed. Transverse stiffeners are disposed within the inner volume and the foam, and extend between the opposed rails. The door panel may be made by continuously providing the front facer with a rail secured thereto, continuously positioning transverse stiffeners on the front facer and extending between the metal rails, and continuously applying a foaming material on the front facer and the transverse stiffeners. The method concludes by bringing a rear facer into contact with the metal rails, and drawing the panel through a laminator. Hardware may then be attached to one or both of the facers and the stiffener. | 11-05-2009 |
| 20110108212 | MOVABLE BARRIERS HAVING TRANSVERSE STIFFENERS AND METHODS OF MAKING THE SAME - A movable door panel having a front facer with opposed longitudinal edge profiles, rails secured to the longitudinal edge profiles, a rear facer secured to the rails, and foam disposed within an inner volume defined by the front facer, the rails and the rear facer is disclosed. Transverse stiffeners are disposed within the inner volume and the foam, and extend between the opposed rails. The door panel may be made by continuously providing the front facer with a rail secured thereto, continuously positioning transverse stiffeners on the front facer and extending between the metal rails, and continuously applying a foaming material on the front facer and the transverse stiffeners. The method concludes by bringing a rear facer into contact with the metal rails, and drawing the panel through a laminator. Hardware may then be attached to one or both of the facers and the stiffener. | 05-12-2011 |
Steven Kridel, Clemmons, NC US
| Patent application number | Description | Published |
|---|---|---|
| 20110190400 | Novel Compounds for Treatment of Malignant Tumors - The present invention comprises compounds, compositions and methods of use for sensitizing cancer cells, tumors, neoplasms, and malignancies to the effects of ionizing radiation used in the treatment of cancer. The invention further comprises a method of identifying novel radiosensitizing compounds. | 08-04-2011 |
Steven J. Kridel, La Jolla, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20090155828 | METHODS OF DETECTING PROSTATE CANCER - Proteins specific for prostate epithelial cells, normal or neoplastic, are identified and used for diagnosis, development of antibodies, and for evaluating drugs that react with the neoplastic specific proteins. Affinity based probes are used that react specifically with the active site to provide a measure of the enzyme activity of the cells. Prostate epithelial neoplastic cells can be used in screening candidate drugs for their effect in changing the proteome profile as to the serine-threonine hydrolase enzymes, using the affinity based probes for determining the profile. | 06-18-2009 |
| 20100173982 | NOVEL METHOD FOR THE ASYMMETRIC SYNTHESIS OF BETA-LACTONE COMPOUNDS - The present invention features methods of treating a cancer in a subject by administering an effective amount of a beta-lactone to the subject. The invention also features methods of inhibiting angiogenesis in a subject by administering an effective amount of an inhibitor of fatty acid synthase to the subject. These methods can be used to treat a variety of cancers and other diseases and conditions. The invention also features methods of identifying beta-lactones and other compounds that can be used in the methods of the invention for the treatment of tumors, inhibition of angiogenesis, and the treatment of diseases and conditions that involve pathological angiogenesis. The invention also features methods of synthesizing beta-lactones and features novel beta-lactone compounds. | 07-08-2010 |
Steven J. Kridel, Clemmons, NC US
| Patent application number | Description | Published |
|---|---|---|
| 20090253896 | SELECTIVE SUBSTRATES FOR MATRIX METALLOPROTEINASES - The invention provides isolated MMP-2, MMP-9 and MT1-MMP selective substrate polypeptides or functional peptidomimetics. The selective substrate polypeptides contain the following sequences: MMP-2 selective substrate polypeptides contain SEQ ID NOS:1-27, MMP-9 selective substrate polypeptides contain SEQ ID NOS:28-35, and MT1-MMP selective substrate polypeptide contain SEQ ID NOS:36-40. In addition, the invention provides a method of preferentially directing a moiety to a site of MMP-2 activity by administering to a subject an effective amount of an isolated MMP-2 selective substrate polypeptide containing SEQ ID NOS:45-47 linked to a moiety. Also provided is a method of preferentially directing a moiety to a site of MMP-9 activity by administering to a subject an effective amount of an isolated MMP-9 selective substrate polypeptide containing SEQ ID NO:44 linked to a moiety, and preferentially directing a moiety to a site of MT1-MMP activity by administering to a subject an effective amount of an isolated MT1-MMP selective substrate polypeptide containing SEQ ID NOS:36-40 linked to a moiety. | 10-08-2009 |