| Patent application number | Description | Published |
|---|
| 20090181090 | Protein-Based Carrier System for Overcoming Resistance in Tumour Cells - Nanoparticles, the particle matrix of which is based on at least one protein and has at least one active agent embedded therein and methods of producing the nanoparticles with at least one active agent embedded in the protein matrix are disclosed. The use of the nanoparticles for the treatment of tumours, in particular for the treatment of tumours which are resistant to chemical medicaments is also disclosed. | 07-16-2009 |
| 20090263491 | Polylactide Nanoparticles - A drug targeting system for administering a pharmacologically active substance to the central nervous system of a mammal across the animal's blood brain barrier. The drug targeting system comprises nanoparticles made of poly(DL-lactide) and/or poly(DL-lactide-co-glycolide), a pharmacologically active substance which is absorbed to, adsorbed to, and/or incorporated into the nanoparticles, and either contains TPGS or comprises a pluronic 188 surfactant coating deposited on the drug-loaded nanoparticles. | 10-22-2009 |
| 20100028446 | TRANSPORT OF DRUGS VIA THE BLOOD-BRAIN BARRIER BY MEANS OF APOLIPOPROTEINS - Combination preparations comprising at least one apolipoprotein as one component, and a medicinal agent to be transported via the blood-brain barrier to the central nervous system as a further component. The components are administered simultaneously, separately or sequentially. A method for administering a medicinal agent to the central nervous system is also provided. | 02-04-2010 |
| Patent application number | Description | Published |
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| 20090136166 | Combined Roller- and Slide Bearing - A combined roller- and slide bearing comprises at least one roller bearing having roller elements disposed between inner and outer bushings thereof and a slide bearing having a lubricating gap defined between inner and outer bushings thereof. The roller bearing and the slide bearing are disposed axially adjacent to each other and have the same rotational axis. The roller bearing and the slide bearing are configured such that the roller bearings elastically deform in response to a radially-acting load, thereby reducing the radial thickness of the lubricating gap in a circumferential portion thereof, because the outer bushing of the slide bearing radially shifts relative to the inner bushing of the slide bearing. In this state, the circumferential portion of the slide bearing having the reduced radial thickness undertakes a load-supporting and bearing function. | 05-28-2009 |
| 20100162979 | SWITCHABLE VALVE ACTUATING MECHANISM - A valve actuation device may comprise a camshaft including first and second cams, the second cam having a larger lobe than the first cam. A valve lever includes a first follower component or surface adapted to follow the first cam and a second follower component or surface adapted to follow the second cam. The second follower component or surface may be mounted on or defined by an eccentrically-disposed device, which is rotatable relative to the first follower component or surface. When the rotatability of the second follower component or surface is locked by a latching device, the second follower surface translates the contour of the second cam into actuation of an engine valve and, when the second follower component or surface is freely rotatable, the first follower surface translates the contour of the first cam into actuation of the engine valve. | 07-01-2010 |
| 20100269806 | Method for Operating an Internal Combustion Engine and an Internal Combustion Engine - An engine comprises a power cylinder having a power chamber, a compression cylinder having a compression chamber and a flow-through chamber connected with the compression chamber when a flow-through valve is open and connected with the power chamber when an intake valve is open. The engine is operated by flowing-in fresh charge into the compression chamber while increasing the volume of the compression chamber, compressing the fresh charge while decreasing the volume of the compression chamber, pushing-over the compressed fresh charge into the flow-through chamber, pushing-out the fresh charge into the power chamber, combusting the fresh charge while increasing the volume of the power chamber and discharging the combusted charge while decreasing the volume of the power chamber. The flow-through chamber volume increases during at least a part of the pushing-over step and, at the end thereof, the volume is less than 15% of its maximum volume. | 10-28-2010 |
| 20110083631 | METHOD AND DEVICE FOR REDUCING ROTATIONAL NON-UNIFORMITIES OF THE CRANKSHAFT OF AN INTERNAL COMBUSTION PISTON ENGINE - In a method for reducing rotational non-uniformities of the crankshaft of a piston internal combustion engine, a movable balancing mass component is coupled to the crankshaft in such a way that the kinetic energy of the mass component increases in phases in which the angular speed of the crankshaft would increase if said crankshaft were not coupled to the balancing mass part, and decreases in phases in which the angular speed of the crankshaft would decrease if said crankshaft were not coupled to the balancing mass component. | 04-14-2011 |
