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Kretzschmar, DE

Andreas Kretzschmar, Cunewalde DE

Patent application numberDescriptionPublished
20100173762TOOL CHANGER FOR MACHINE TOOLS - A tool changer for machine tools, the tool changer having at least one rotatable tool gripper, a supporting column for the tool gripper which can be lifted and lowered and rotated about a rotational axis, a mechanical cam gear for generating the lifting and rotating movements of the tool gripper, all driven by a drive motor connected to a cam barrel and intermediate gearing. The cam barrel has a tappet for the rotational drive of the tool gripper on its upper front and a cam curve or groove on its peripheral surface for the lifting movement of the tool gripper. The tappet drives a Maltese wheel supported on a shaft parallel to the rotational axis of the tool gripper. The Maltese wheel, the cam barrel, and the supporting column of the tool gripper are successively supported in a manner parallel to the axis.07-08-2010
20110251035TOOL CHAIN MAGAZINE - A tool chain magazine, in particular for program-controlled milling machines and machining centers, comprising a stationary supporting structure to which linear guiding devices, chain wheels, and a drive assembly as a rotary drive for at least one of the chain wheels are mounted. The tool chain comprises an endless magazine chain consisting of a series of chain links connected in an articulate manner to one another, wherein supporting and guiding elements are provided on each chain link, and each chain link has a respective socket as a holder for a tool taper. The base bodies of the chain links of the magazine chain are formed by the tool stations centrally disposed therein, and the front and rear connecting joints of the chain links are arranged in the longitudinal center axis of the magazine chain.10-13-2011

Bernd Kretzschmar, Radebeul DE

Patent application numberDescriptionPublished
20110272641METHOD OF INCORPORATING AN ADDITIVE INTO A POLYMER COMPOSITION AND DISPERSION USED THEREIN - A method of incorporating an additive into a polymer composition includes the step of melt blending a polymer with a dispersion comprising a liquid carrier, an unmodified clay, and an additive. Using the dispersion rather than a polymer-based additive masterbatch saves energy. Like a polymer-based masterbatch, the dispersion provides the additive in a diluted form and therefore preserves the masterbatch's advantages of providing more uniform distribution additive in the plastic and avoiding direct handling of additives in the final compounding step. The dispersion is also described.11-10-2011
20120070598POLYOLEFIN COMPOSITION - A polyolefin composition having an increased modulus of elasticity as well as increased heat resistance, wherein the polymer composition has high melt viscosity, and wherein the composition contains a carbon material as a filler, wherein the filler is present in the form of a carbon nanofiber.03-22-2012

Christel Kretzschmar, Dohna DE

Patent application numberDescriptionPublished
20110005831CONNECTION PIN AND ELECTRICAL CONNECTION - A hookup stem (01-13-2011

Eike Kretzschmar, Zwingenberg DE

Patent application numberDescriptionPublished
20090324918Preparation of transparent high density polyethylene sheets - A transparent high density polyethylene (HDPE) sheet is disclosed. The sheet has a thickness greater than or equal to 0.05 mm and a bulk haze less than 2%. The HDPE resin is converted into a sheet by thermal processing and the sheet is then uniaxially oriented at a temperature above the melting point of the HDPE resin. The transparent HDPE sheet of the invention can be used for windows and plastic containers.12-31-2009

Eva Kretzschmar, Mannheim DE

Patent application numberDescriptionPublished
20110124905PROCESS FOR PREPARING PLASTICS USING 1,6-HEXANEDIOL HAVING AN ALDEHYDE CONTENT OF LESS THAN 500 PPM - The present invention relates to a process for preparing plastics using 1,6-hexanediol having an aldehyde content of less than 500 ppm, a process for preparing 1,6-hexanediol having an aldehyde content of less than 500 ppm and also 1,6-hexanediol having an aldehyde content of less than 500 ppm.05-26-2011
20120059174PROCESS FOR PREPARING EPSILON-CAPROLACTONE AND 1,6-HEXANEDIOL - The invention relates to processes for preparing 1,6-hexanediol and very pure ε-caprolactone from a dicarboxylic acid solution (DCS), comprising the steps of (a) esterification of the DCS with alcohols, (b) partial catalytic hydrogenation of the esters, (c) distillative removal of 1,6-hexanediol and low boilers as the top product, and (d) cyclization of the 6-hydroxycaproic ester present in the bottoms fraction in the presence of a higher-boiling alcohol than caprolactone.03-08-2012

Gerhard Kretzschmar, Frankfurt DE

Patent application numberDescriptionPublished
20110230669PROCESS FOR THE PRODUCTION OF ARTEMISININ INTERMEDIATES - This application relates to a process for the production of (2R)-dihydroartemisinic acid or (2R)-dihydroartemisinic acid esters from artemisinic acid or artemisinic acid esters, respectively, by diimine hydrogenation of the exocyclic CC-double bond, and use of said process in the production of the antimalarial drug artemisinin.09-22-2011

Gerhard Kretzschmar, Frankfurt Am Main DE

Patent application numberDescriptionPublished
20120065411PROCESS FOR THE PRODUCTION OF BENZOFURANS - A process for the production of 2-alkyl-3-aroyl-5-nitrobenzofurans by acylation of 2-(2-hydroxy-5-nitrophenyl)-1-aryl-ethanones and subsequent treatment of the esters with combinations of bases and proton acids or Lewis acids. This process can be used for the production of Dronedarone. Furthermore, novel intermediates for the manufacture of Dronedarone are provided.03-15-2012
20120077995PROCESS FOR THE PRODUCTION OF DRONEDARONE INTERMEDIATES - A process for the production of Dronedarone intermediates of the formula (I), by acylation of 2-(2-hydroxy-5-nitrophenyl)-1-(4-methoxyphenyl)-ethanone, subsequent treatment of the ester with bases and a zeolite (alumosilicate) catalyst and optional subsequent demethylation. This process can be used for the production of Dronedarone.03-29-2012

Hans Kretzschmar, Wolfratshausen DE

Patent application numberDescriptionPublished
20100029773Systematic identification of new anti-prion drugs by high-throughput screening based on scanning for intensely fluorescent targets (sift) - The present invention relates to a method of identifying a compound for inhibiting aggregation of proteins involved in diseases linked to protein aggregation and/or neurodegenerative diseases, comprising the steps of: (a) bringing into contact a labeled monomeric protein and a differently labeled aggregate of said protein in the (1) presence and (2) absence of a candidate inhibitor of aggregation, (b) determining the amount of co-localized labels, representing the extent of binding of the monomeric proteins to the aggregates of said protein; and (c) comparing the result obtained in the presence and absence of said compound, wherein a decrease of co-localized labels in the presence of said compound is indicative of the compound's ability to inhibit aggregation of said protein. Moreover, the present invention relates to a pharmaceutical composition containing said inhibitor of aggregation as well as to a kit.02-04-2010
20110293520NEW DRUG FOR INHIBITING AGGREGATION OF PROTEINS INVOLVED IN DISEASES LINKED TO PROTEIN AGGREGATION AND/OR NEURODEGENERATIVE DISEASES - The present invention relates to a compound represented by formula (E). The present invention also relates to a compound represented by the formula (E) for use in the treatment or prevention of diseases linked to protein aggregation and/or neurodegenerative diseases. Moreover, the present invention relates to pharmaceutical and diagnostic compositions comprising the compound of the invention as well as to a kit. Furthermore, the present invention relates to a method of imaging deposits of aggregated protein. A kit for preparing a detectably labelled compound of the present invention is also disclosed. Formula (E) wherein X, Y and L are independently nondirectionally selected from —C(R12-01-2011

Jan Kretzschmar, Stuttgart DE

Patent application numberDescriptionPublished
20110148136MOTOR VEHICLE - A motor vehicle has a storage compartment which contains a housing and a lid which closes the housing. The storage compartment further has a locking mechanism which has a housing-side closing bar and a lid-side bolt which interacts with the latter and which engages behind the closing bar in the locked state and releases from the closing bar through rotation. The storage compartment is arranged essentially vertically between two rear seats of the motor vehicle, wherein the lid can be adjusted between a closed position which abuts against the housing and an open position which is moved forward. An arrestor hook, which is formed as an emergency securing device, is arranged on an inner side of the lid. If force is suddenly applied to the housing in the direction of the lid, in particular in the event of a crash, the arrestor hook engages behind the closing bar and as a result prevents undesired opening of the lid.06-23-2011

Klaus Kretzschmar, Angelbachtal DE

Patent application numberDescriptionPublished
20100153167INCORPORATING WORKFLOW PROCESS MODIFICATIONS - Apparatus, systems, and methods are disclosed that operate to create and access electronic content comprising document files that comprise workflow definitions having information about a plurality of activities in the workflow process chain, including prior activities, the current activity, and subsequent activities. Such documents also contain instructions as part of the workflow definition which, when executed, cause modifications to the workflow definition to be recorded in the document file. Execution of the instructions may also result in identifying a subsequent processing entity to process the document file during subsequent activities in the workflow process chain, based on the embedded information. Additional apparatus, systems, and methods are disclosed.06-17-2010
20100299378SORTABLE FLOATING POINT NUMBERS - The invention comprises methods for manipulating floating point numbers on a microprocessor where the numbers are sortable. That is, the numbers obey lexicographical ordering. Hence, the numbers may be quickly compared using bit-wise comparison functions such as memcmp( ). Conversion may result in a sortable floating point number in the form of a sign, leading bits of the exponent, and sets of digit triples in the form of declets (sets of 10 bits). In a variable-length version, numbers may be compressed by storing the number of trailing zero declets in lieu of storing the zero declets themselves.11-25-2010
20100306289SORTABLE FLOATING POINT NUMBERS - The invention comprises methods for manipulating floating point numbers on a microprocessor where the numbers are sortable. That is, the numbers obey lexicographical ordering. Hence, the numbers may be quickly compared using bit-wise comparison functions such as memcmp( ). Conversion may result in a sortable floating point number in the form of a sign, leading bits of the exponent, and sets of digit triples in the form of declets (sets of 10 bits). In a variable-length version, numbers may be compressed by storing the number of trailing zero declets in lieu of storing the zero declets themselves.12-02-2010

Markus Kretzschmar, Altrip DE

Patent application numberDescriptionPublished
20100071593MATTING AGENT - A matting agent useful for the preparation of matted coatings comprising, inorganic oxide particulates and wax coated on the inorganic oxide particulates, wherein the wax possesses a crystallinity of about 50% or more.03-25-2010

Michael Kretzschmar, Hamburg DE

Patent application numberDescriptionPublished
20110039473Construction Kit - Construction kit with two- and/or three-dimensional construction elements (02-17-2011

Patent applications by Michael Kretzschmar, Hamburg DE

Ralf Kretzschmar, Dresden DE

Patent application numberDescriptionPublished
20080299336Calcinated or Sintered Hollow Body Comprising a Spherically Curved Surface - A method is for producing calcinated or sintered hollow bodies comprising a spherical surface, to hollow bodies produced using the method, and to the uses thereof. Calcinated or sintered hollow bodies comprising a spherically curved surface, an enlarged, freely accessible surface and/or a structured surface. An organic spherical carrier is coated with a powder which forms the shell of a hollow body, and a binding agent, both contained in suspension. A heat treatment is then carried out, leading to the expulsion of organic constituents and to the sintering process. At least one elevation is arranged on the surface of the carrier or embodied thereon, the projection past the surface corresponding at least to the thickness of the shell of the finished sintered hollow body, taking into account the degree of shrinkage of the powder material during the sintering process. The elevation(s) is/are then removed by conversion into the gas phase of the respective material from which they are formed and/or mechanically, during the heat treatment.12-04-2008
20100130805METHOD AND DEVICE FOR INACTIVATING A MICROBIOLOGICALLY CONTAMINATED MASS CONTAINING SOLID PARTICLES WITH ACCELERATED ELECTRONS - Method and device for inactivating a microbiologically contaminated mass containing solid particles. The method includes mixing the mass containing solid particles with a gelatinizing agent, transporting the mixed mass of solid particles and gelatinizing agent through a shaping device structured so that the mixed mass, at least in one area, is shaped to form a lamellar volume with a layer thickness of between 1 mm and 3 mm, and impinging the formed lamellar volume of the mixed mass with accelerated electrons.05-27-2010

Patent applications by Ralf Kretzschmar, Dresden DE

Titus Kretzschmar, Hurlach DE

Patent application numberDescriptionPublished
20100172907Anti-Abeta antibodies and their use - The present invention relates to antibody molecules capable of specifically recognizing two regions of the β-A4 peptide, wherein the first region comprises the amino acid sequence AEFRHDSGY as shown in SEQ ID NO: 1 or a fragment thereof and wherein the second region comprises the amino acid sequence VHHQKLVFFAEDVG as shown in SEQ ID NO: 2 or a fragment thereof. Furthermore, nucleic acid molecules encoding the inventive antibody molecules and vectors and hosts comprising said nucleic acid molecules are disclosed. In addition, the present invention provides for compositions, preferably pharmaceutical or diagnostic compositions, comprising the compounds of the invention as well as for specific uses of the antibody molecules, nucleic acid molecules, vectors or hosts of the invention.07-08-2010

Wolfram Kretzschmar, Chemnitz DE

Patent application numberDescriptionPublished
20120111162DEVICE AND METHOD FOR PRODUCING MONOAXIAL OR MULTIAXIAL SCRIMS - Device and method for producing scrims of fiber bands. The device includes a dispensing arrangement structured and arranged for dispensing fiber bands, a severing device structured and arranged for cutting the fiber bands to a cut length and comprising a knife with a cutting edge displaceable in a direction of an extension of the cutting edge, a conveyor device structured and arranged for conveying at least one layer of fiber bands to a bonding device, and a transport device structured and arranged to deposit the cut length fiber bands onto the conveyor device.05-10-2012